UniProtKB - P14131 (RS16_MOUSE)
Protein
40S ribosomal protein S16
Gene
Rps16
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: MGI
- structural constituent of ribosome Source: GO_Central
GO - Biological processi
- cellular response to leukemia inhibitory factor Source: MGI
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
- ribosomal small subunit biogenesis Source: MGI
- rRNA processing Source: MGI
- translation Source: InterPro
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-MMU-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-MMU-1799339, SRP-dependent cotranslational protein targeting to membrane R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-MMU-72649, Translation initiation complex formation R-MMU-72689, Formation of a pool of free 40S subunits R-MMU-72695, Formation of the ternary complex, and subsequently, the 43S complex R-MMU-72702, Ribosomal scanning and start codon recognition R-MMU-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-MMU-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-MMU-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Names & Taxonomyi
Protein namesi | Recommended name: 40S ribosomal protein S16 |
Gene namesi | Name:Rps16 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:98118, Rps16 |
Subcellular locationi
Cytosol
- cytosolic small ribosomal subunit Source: MGI
Other locations
- small ribosomal subunit Source: UniProtKB
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000111480 | 1 – 146 | 40S ribosomal protein S16Add BLAST | 146 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 3 | PhosphoserineBy similarity | 1 | |
Modified residuei | 60 | N6-acetyllysineBy similarity | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | P14131 |
jPOSTi | P14131 |
MaxQBi | P14131 |
PaxDbi | P14131 |
PRIDEi | P14131 |
PTM databases
iPTMneti | P14131 |
PhosphoSitePlusi | P14131 |
SwissPalmi | P14131 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000037563, Expressed in liver and 53 other tissues |
Genevisiblei | P14131, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 203004, 98 interactors |
ComplexPortali | CPX-5261, 40S cytosolic small ribosomal subunit |
IntActi | P14131, 9 interactors |
MINTi | P14131 |
STRINGi | 10090.ENSMUSP00000103940 |
Miscellaneous databases
RNActi | P14131, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uS9 family.Curated
Phylogenomic databases
eggNOGi | KOG1753, Eukaryota |
GeneTreei | ENSGT00390000013067 |
HOGENOMi | CLU_046483_4_0_1 |
InParanoidi | P14131 |
OMAi | FMGQAEA |
OrthoDBi | 1347615at2759 |
TreeFami | TF300088 |
Family and domain databases
Gene3Di | 3.30.230.10, 1 hit |
InterProi | View protein in InterPro IPR020568, Ribosomal_S5_D2-typ_fold IPR014721, Ribosomal_S5_D2-typ_fold_subgr IPR000754, Ribosomal_S9 IPR020574, Ribosomal_S9_CS |
PANTHERi | PTHR21569, PTHR21569, 1 hit |
Pfami | View protein in Pfam PF00380, Ribosomal_S9, 1 hit |
SUPFAMi | SSF54211, SSF54211, 1 hit |
PROSITEi | View protein in PROSITE PS00360, RIBOSOMAL_S9, 1 hit |
i Sequence
Sequence statusi: Complete.
P14131-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPSKGPLQSV QVFGRKKTAT AVAHCKRGNG LIKVNGRPLE MIEPRTLQYK
60 70 80 90 100
LLEPVLLLGK ERFAGVDIRV RVKGGGHVAQ IYAIRQSISK ALVAYYQKYV
110 120 130 140
DEASKKEIKD ILIQYDRTLL VADPRRCESK KFGGPGARAR YQKSYR
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 19 – 20 | AT → L in AAA03646 (PubMed:3915781).Curated | 2 | |
Sequence conflicti | 46 | T → A in AAA03646 (PubMed:3915781).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M11408 Unassigned DNA Translation: AAA03646.1 AK010613 mRNA Translation: BAB27062.1 AK010641 mRNA Translation: BAB27083.1 AK011060 mRNA Translation: BAB27368.1 AK019400 mRNA Translation: BAB31702.1 AK083946 mRNA Translation: BAC39077.1 AK088413 mRNA Translation: BAC40341.1 AK088716 mRNA Translation: BAC40524.1 AK150808 mRNA Translation: BAE29871.1 AK168207 mRNA Translation: BAE40167.1 AK169328 mRNA Translation: BAE41081.1 |
CCDSi | CCDS39858.1 |
PIRi | S11623, R3MS16 |
RefSeqi | NP_038675.2, NM_013647.2 |
Genome annotation databases
Ensembli | ENSMUST00000082134; ENSMUSP00000103940; ENSMUSG00000037563 |
GeneIDi | 20055 |
KEGGi | mmu:20055 |
UCSCi | uc012fgr.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M11408 Unassigned DNA Translation: AAA03646.1 AK010613 mRNA Translation: BAB27062.1 AK010641 mRNA Translation: BAB27083.1 AK011060 mRNA Translation: BAB27368.1 AK019400 mRNA Translation: BAB31702.1 AK083946 mRNA Translation: BAC39077.1 AK088413 mRNA Translation: BAC40341.1 AK088716 mRNA Translation: BAC40524.1 AK150808 mRNA Translation: BAE29871.1 AK168207 mRNA Translation: BAE40167.1 AK169328 mRNA Translation: BAE41081.1 |
CCDSi | CCDS39858.1 |
PIRi | S11623, R3MS16 |
RefSeqi | NP_038675.2, NM_013647.2 |
3D structure databases
SMRi | P14131 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 203004, 98 interactors |
ComplexPortali | CPX-5261, 40S cytosolic small ribosomal subunit |
IntActi | P14131, 9 interactors |
MINTi | P14131 |
STRINGi | 10090.ENSMUSP00000103940 |
PTM databases
iPTMneti | P14131 |
PhosphoSitePlusi | P14131 |
SwissPalmi | P14131 |
Proteomic databases
EPDi | P14131 |
jPOSTi | P14131 |
MaxQBi | P14131 |
PaxDbi | P14131 |
PRIDEi | P14131 |
Protocols and materials databases
Antibodypediai | 30342, 194 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000082134; ENSMUSP00000103940; ENSMUSG00000037563 |
GeneIDi | 20055 |
KEGGi | mmu:20055 |
UCSCi | uc012fgr.1, mouse |
Organism-specific databases
CTDi | 6217 |
MGIi | MGI:98118, Rps16 |
Phylogenomic databases
eggNOGi | KOG1753, Eukaryota |
GeneTreei | ENSGT00390000013067 |
HOGENOMi | CLU_046483_4_0_1 |
InParanoidi | P14131 |
OMAi | FMGQAEA |
OrthoDBi | 1347615at2759 |
TreeFami | TF300088 |
Enzyme and pathway databases
Reactomei | R-MMU-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-MMU-1799339, SRP-dependent cotranslational protein targeting to membrane R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-MMU-72649, Translation initiation complex formation R-MMU-72689, Formation of a pool of free 40S subunits R-MMU-72695, Formation of the ternary complex, and subsequently, the 43S complex R-MMU-72702, Ribosomal scanning and start codon recognition R-MMU-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-MMU-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-MMU-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Miscellaneous databases
BioGRID-ORCSi | 20055, 8 hits in 18 CRISPR screens |
ChiTaRSi | Rps16, mouse |
PROi | PR:P14131 |
RNActi | P14131, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000037563, Expressed in liver and 53 other tissues |
Genevisiblei | P14131, MM |
Family and domain databases
Gene3Di | 3.30.230.10, 1 hit |
InterProi | View protein in InterPro IPR020568, Ribosomal_S5_D2-typ_fold IPR014721, Ribosomal_S5_D2-typ_fold_subgr IPR000754, Ribosomal_S9 IPR020574, Ribosomal_S9_CS |
PANTHERi | PTHR21569, PTHR21569, 1 hit |
Pfami | View protein in Pfam PF00380, Ribosomal_S9, 1 hit |
SUPFAMi | SSF54211, SSF54211, 1 hit |
PROSITEi | View protein in PROSITE PS00360, RIBOSOMAL_S9, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RS16_MOUSE | |
Accessioni | P14131Primary (citable) accession number: P14131 Secondary accession number(s): Q3THM9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1990 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 163 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries