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Protein

50S ribosomal protein L18

Gene

rpl18

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, where it forms part of the central protuberance and stabilizes the orientation of adjacent RNA domains.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L18
Alternative name(s):
Hl12
Hmal18
Gene namesi
Name:rpl18
Ordered Locus Names:rrnAC1593
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHaloarculaceaeHaloarcula
Proteomesi
  • UP000001169 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001314002 – 18750S ribosomal protein L18Add BLAST186

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Interacts with proteins L5 and L21e, and attaches the 5S rRNA to the 23S rRNA. Has been cross-linked to L21e.2 Publications

Protein-protein interaction databases

STRINGi272569.rrnAC1593

Structurei

Secondary structure

1187
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 6Combined sources3
Helixi12 – 15Combined sources4
Helixi21 – 28Combined sources8
Beta strandi34 – 39Combined sources6
Beta strandi44 – 50Combined sources7
Beta strandi53 – 55Combined sources3
Beta strandi57 – 64Combined sources8
Helixi65 – 70Combined sources6
Beta strandi76 – 78Combined sources3
Helixi79 – 95Combined sources17
Beta strandi102 – 104Combined sources3
Helixi115 – 125Combined sources11
Helixi134 – 136Combined sources3
Helixi140 – 144Combined sources5
Helixi146 – 153Combined sources8
Beta strandi159 – 162Combined sources4
Helixi170 – 181Combined sources12
Beta strandi182 – 185Combined sources4

3D structure databases

ProteinModelPortaliP14123
SMRiP14123
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP14123

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG04088 Archaea
COG0256 LUCA
HOGENOMiHOG000105947
KOiK02881
OMAiMAHGPRY
OrthoDBiPOG093Z0CXG

Family and domain databases

HAMAPiMF_01337_A Ribosomal_L18_A, 1 hit
InterProiView protein in InterPro
IPR005485 Rbsml_L5_euk/L18_arc
PANTHERiPTHR23410 PTHR23410, 2 hits
PfamiView protein in Pfam
PF17144 Ribosomal_L5e, 2 hits
PRINTSiPR00058 RIBOSOMALL5

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14123-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATGPRYKVP MRRRREARTD YHQRLRLLKS GKPRLVARKS NKHVRAQLVT
60 70 80 90 100
LGPNGDDTLA SAHSSDLAEY GWEAPTGNMP SAYLTGLLAG LRAQEAGVEE
110 120 130 140 150
AVLDIGLNSP TPGSKVFAIQ EGAIDAGLDI PHNDDVLADW QRTRGAHIAE
160 170 180
YDEQLEEPLY SGDFDAADLP EHFDELRETL LDGDIEL
Length:187
Mass (Da):20,614
Last modified:January 23, 2007 - v3
Checksum:i60E9AF3CB64E7CA5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti18R → A AA sequence (PubMed:3196689).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X58395 Genomic DNA Translation: CAA41290.1
AY596297 Genomic DNA Translation: AAV46511.1
PIRiS16541 R5HS18
RefSeqiWP_011223738.1, NC_006396.1

Genome annotation databases

EnsemblBacteriaiAAV46511; AAV46511; rrnAC1593
GeneIDi3127918
KEGGihma:rrnAC1593
PATRICifig|272569.17.peg.2282

Similar proteinsi

Entry informationi

Entry nameiRL18_HALMA
AccessioniPrimary (citable) accession number: P14123
Secondary accession number(s): Q5V1U1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 137 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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