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Protein

50S ribosomal protein L18

Gene

rpl18

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, where it forms part of the central protuberance and stabilizes the orientation of adjacent RNA domains.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L18
Alternative name(s):
Hl12
Hmal18
Gene namesi
Name:rpl18
Ordered Locus Names:rrnAC1593
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaStenosarchaea groupHalobacteriaHalobacterialesHaloarculaceaeHaloarcula
Proteomesi
  • UP000001169 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001314002 – 18750S ribosomal protein L18Add BLAST186

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Interacts with proteins L5 and L21e, and attaches the 5S rRNA to the 23S rRNA. Has been cross-linked to L21e.2 Publications

Protein-protein interaction databases

STRINGi272569.rrnAC1593

Structurei

Secondary structure

1187
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP14123
SMRiP14123
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP14123

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG04088 Archaea
COG0256 LUCA
HOGENOMiHOG000105947
KOiK02881
OMAiMAHGPRY
OrthoDBiPOG093Z0CXG

Family and domain databases

HAMAPiMF_01337_A Ribosomal_L18_A, 1 hit
InterProiView protein in InterPro
IPR005485 Rbsml_L5_euk/L18_arc
PANTHERiPTHR23410 PTHR23410, 2 hits
PfamiView protein in Pfam
PF17144 Ribosomal_L5e, 2 hits
PRINTSiPR00058 RIBOSOMALL5

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14123-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATGPRYKVP MRRRREARTD YHQRLRLLKS GKPRLVARKS NKHVRAQLVT
60 70 80 90 100
LGPNGDDTLA SAHSSDLAEY GWEAPTGNMP SAYLTGLLAG LRAQEAGVEE
110 120 130 140 150
AVLDIGLNSP TPGSKVFAIQ EGAIDAGLDI PHNDDVLADW QRTRGAHIAE
160 170 180
YDEQLEEPLY SGDFDAADLP EHFDELRETL LDGDIEL
Length:187
Mass (Da):20,614
Last modified:January 23, 2007 - v3
Checksum:i60E9AF3CB64E7CA5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti18R → A AA sequence (PubMed:3196689).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X58395 Genomic DNA Translation: CAA41290.1
AY596297 Genomic DNA Translation: AAV46511.1
PIRiS16541 R5HS18
RefSeqiWP_011223738.1, NC_006396.1

Genome annotation databases

EnsemblBacteriaiAAV46511; AAV46511; rrnAC1593
GeneIDi3127918
KEGGihma:rrnAC1593
PATRICifig|272569.17.peg.2282

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X58395 Genomic DNA Translation: CAA41290.1
AY596297 Genomic DNA Translation: AAV46511.1
PIRiS16541 R5HS18
RefSeqiWP_011223738.1, NC_006396.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40K2-186[»]
1JJ2X-ray2.40M2-187[»]
1K73X-ray3.01O2-187[»]
1K8AX-ray3.00O2-187[»]
1K9MX-ray3.00O2-187[»]
1KC8X-ray3.01O2-187[»]
1KD1X-ray3.00O2-187[»]
1KQSX-ray3.10M2-187[»]
1M1KX-ray3.20O2-187[»]
1M90X-ray2.80O2-187[»]
1N8RX-ray3.00O2-187[»]
1NJIX-ray3.00O2-187[»]
1Q7YX-ray3.20O2-187[»]
1Q81X-ray2.95O2-187[»]
1Q82X-ray2.98O2-187[»]
1Q86X-ray3.00O2-187[»]
1QVFX-ray3.10M2-187[»]
1QVGX-ray2.90M2-187[»]
1S72X-ray2.40N1-187[»]
1VQ4X-ray2.70N1-187[»]
1VQ5X-ray2.60N1-187[»]
1VQ6X-ray2.70N1-187[»]
1VQ7X-ray2.50N1-187[»]
1VQ8X-ray2.20N1-187[»]
1VQ9X-ray2.40N1-187[»]
1VQKX-ray2.30N1-187[»]
1VQLX-ray2.30N1-187[»]
1VQMX-ray2.30N1-187[»]
1VQNX-ray2.40N1-187[»]
1VQOX-ray2.20N1-187[»]
1VQPX-ray2.25N1-187[»]
1W2BX-ray3.50M2-187[»]
1YHQX-ray2.40N1-187[»]
1YI2X-ray2.65N1-187[»]
1YIJX-ray2.60N1-187[»]
1YITX-ray2.80N1-187[»]
1YJ9X-ray2.90N1-187[»]
1YJNX-ray3.00N1-187[»]
1YJWX-ray2.90N1-187[»]
2OTJX-ray2.90N1-187[»]
2OTLX-ray2.70N1-187[»]
2QA4X-ray3.00N1-187[»]
2QEXX-ray2.90N1-187[»]
3CC2X-ray2.40N1-187[»]
3CC4X-ray2.70N1-187[»]
3CC7X-ray2.70N1-187[»]
3CCEX-ray2.75N1-187[»]
3CCJX-ray2.70N1-187[»]
3CCLX-ray2.90N1-187[»]
3CCMX-ray2.55N1-187[»]
3CCQX-ray2.90N1-187[»]
3CCRX-ray3.00N1-187[»]
3CCSX-ray2.95N1-187[»]
3CCUX-ray2.80N1-187[»]
3CCVX-ray2.90N1-187[»]
3CD6X-ray2.75N1-187[»]
3CMAX-ray2.80N1-187[»]
3CMEX-ray2.95N1-187[»]
3CPWX-ray2.70M1-187[»]
3CXCX-ray3.00M2-187[»]
3G4SX-ray3.20N2-187[»]
3G6EX-ray2.70N2-187[»]
3G71X-ray2.85N2-187[»]
3I55X-ray3.11N1-187[»]
3I56X-ray2.90N1-187[»]
3OW2X-ray2.70M2-187[»]
4ADXelectron microscopy6.60N1-187[»]
4V4RX-ray5.90S2-187[»]
4V4SX-ray6.76S2-187[»]
4V4TX-ray6.46S2-187[»]
4V9FX-ray2.40N1-187[»]
ProteinModelPortaliP14123
SMRiP14123
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272569.rrnAC1593

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV46511; AAV46511; rrnAC1593
GeneIDi3127918
KEGGihma:rrnAC1593
PATRICifig|272569.17.peg.2282

Phylogenomic databases

eggNOGiarCOG04088 Archaea
COG0256 LUCA
HOGENOMiHOG000105947
KOiK02881
OMAiMAHGPRY
OrthoDBiPOG093Z0CXG

Miscellaneous databases

EvolutionaryTraceiP14123

Family and domain databases

HAMAPiMF_01337_A Ribosomal_L18_A, 1 hit
InterProiView protein in InterPro
IPR005485 Rbsml_L5_euk/L18_arc
PANTHERiPTHR23410 PTHR23410, 2 hits
PfamiView protein in Pfam
PF17144 Ribosomal_L5e, 2 hits
PRINTSiPR00058 RIBOSOMALL5
ProtoNetiSearch...

Entry informationi

Entry nameiRL18_HALMA
AccessioniPrimary (citable) accession number: P14123
Secondary accession number(s): Q5V1U1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 23, 2007
Last modified: October 10, 2018
This is version 138 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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