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UniProtKB - P14119 (RL19E_HALMA)
Protein
50S ribosomal protein L19e
Gene
rpl19e
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Functioni
Binds to the 23S rRNA. Located at the polypeptide exit tunnel on the outside of the subunit.
GO - Molecular functioni
- large ribosomal subunit rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L19eUniRule annotationAlternative name(s): Hl24 Hmal19 |
Gene namesi | Name:rpl19eUniRule annotation Ordered Locus Names:rrnAC1594 |
Organismi | Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) |
Taxonomic identifieri | 272569 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Haloarculaceae › Haloarcula › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed1 Publication | |||
ChainiPRO_0000131187 | 2 – 149 | 50S ribosomal protein L19eAdd BLAST | 148 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit.
UniRule annotation3 PublicationsProtein-protein interaction databases
IntActi | P14119, 2 interactors |
STRINGi | 272569.rrnAC1594 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P14119 |
SMRi | P14119 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P14119 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 45 – 130 | DisorderedSequence analysisAdd BLAST | 86 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 45 – 61 | Basic and acidic residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 62 – 77 | Basic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 86 – 115 | Basic and acidic residuesSequence analysisAdd BLAST | 30 |
Sequence similaritiesi
Belongs to the eukaryotic ribosomal protein eL19 family.UniRule annotation
Phylogenomic databases
eggNOGi | arCOG04089, Archaea |
HOGENOMi | CLU_083919_1_1_2 |
OMAi | NRVWIDP |
Family and domain databases
CDDi | cd01418, Ribosomal_L19e_A, 1 hit |
Gene3Di | 1.10.1200.60, 1 hit 1.10.1650.10, 1 hit 1.20.5.560, 1 hit |
HAMAPi | MF_01475, Ribosomal_L19e, 1 hit |
InterProi | View protein in InterPro IPR035970, 60S_ribosomal_L19/L19e_sf IPR000196, Ribosomal_L19/L19e IPR023638, Ribosomal_L19/L19e_CS IPR015972, Ribosomal_L19/L19e_dom1 IPR033936, Ribosomal_L19e_A IPR015973, Ribosomal_L19e_dom2 IPR015974, Ribosomal_L19e_dom3 IPR039547, RPL19 |
PANTHERi | PTHR10722, PTHR10722, 1 hit |
Pfami | View protein in Pfam PF01280, Ribosomal_L19e, 1 hit |
SMARTi | View protein in SMART SM01416, Ribosomal_L19e, 1 hit |
SUPFAMi | SSF48140, SSF48140, 1 hit |
PROSITEi | View protein in PROSITE PS00526, RIBOSOMAL_L19E, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P14119-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTDLSAQKRL AADVLDVGKN RVWFNPERQG DIADAITRED VRELVDEGAI
60 70 80 90 100
QAKDKKGNSR GRARERQKKR AYGHQKGAGS RKGKAGARQN SKEDWESRIR
110 120 130 140
AQRTKLRELR DEGTLSSSQY RDLYDKAGGG EFDSVADLER YIDANHGDA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 82 | K → G AA sequence (PubMed:2591382).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X58395 Genomic DNA Translation: CAA41289.1 AY596297 Genomic DNA Translation: AAV46512.1 |
PIRi | S16540, R5HSH4 |
RefSeqi | WP_004516953.1, NZ_CP039138.1 |
Genome annotation databases
EnsemblBacteriai | AAV46512; AAV46512; rrnAC1594 |
GeneIDi | 40152559 64821833 |
KEGGi | hma:rrnAC1594 |
PATRICi | fig|272569.17.peg.2283 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X58395 Genomic DNA Translation: CAA41289.1 AY596297 Genomic DNA Translation: AAV46512.1 |
PIRi | S16540, R5HSH4 |
RefSeqi | WP_004516953.1, NZ_CP039138.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1FFK | X-ray | 2.40 | M | 2-149 | [»] | |
1JJ2 | X-ray | 2.40 | O | 2-149 | [»] | |
1K73 | X-ray | 3.01 | Q | 2-149 | [»] | |
1K8A | X-ray | 3.00 | Q | 2-149 | [»] | |
1K9M | X-ray | 3.00 | Q | 2-149 | [»] | |
1KC8 | X-ray | 3.01 | Q | 2-149 | [»] | |
1KD1 | X-ray | 3.00 | Q | 2-149 | [»] | |
1KQS | X-ray | 3.10 | O | 2-149 | [»] | |
1M1K | X-ray | 3.20 | Q | 2-149 | [»] | |
1M90 | X-ray | 2.80 | Q | 2-149 | [»] | |
1N8R | X-ray | 3.00 | Q | 2-149 | [»] | |
1NJI | X-ray | 3.00 | Q | 2-149 | [»] | |
1Q7Y | X-ray | 3.20 | Q | 2-149 | [»] | |
1Q81 | X-ray | 2.95 | Q | 2-149 | [»] | |
1Q82 | X-ray | 2.98 | Q | 2-149 | [»] | |
1Q86 | X-ray | 3.00 | Q | 2-149 | [»] | |
1QVF | X-ray | 3.10 | O | 2-149 | [»] | |
1QVG | X-ray | 2.90 | O | 2-149 | [»] | |
1S72 | X-ray | 2.40 | P | 1-149 | [»] | |
1VQ4 | X-ray | 2.70 | P | 1-149 | [»] | |
1VQ5 | X-ray | 2.60 | P | 1-149 | [»] | |
1VQ6 | X-ray | 2.70 | P | 1-149 | [»] | |
1VQ7 | X-ray | 2.50 | P | 1-149 | [»] | |
1VQ8 | X-ray | 2.20 | P | 1-149 | [»] | |
1VQ9 | X-ray | 2.40 | P | 1-149 | [»] | |
1VQK | X-ray | 2.30 | P | 1-149 | [»] | |
1VQL | X-ray | 2.30 | P | 1-149 | [»] | |
1VQM | X-ray | 2.30 | P | 1-149 | [»] | |
1VQN | X-ray | 2.40 | P | 1-149 | [»] | |
1VQO | X-ray | 2.20 | P | 1-149 | [»] | |
1VQP | X-ray | 2.25 | P | 1-149 | [»] | |
1W2B | X-ray | 3.50 | O | 2-149 | [»] | |
1YHQ | X-ray | 2.40 | P | 1-149 | [»] | |
1YI2 | X-ray | 2.65 | P | 1-149 | [»] | |
1YIJ | X-ray | 2.60 | P | 1-149 | [»] | |
1YIT | X-ray | 2.80 | P | 1-149 | [»] | |
1YJ9 | X-ray | 2.90 | P | 1-149 | [»] | |
1YJN | X-ray | 3.00 | P | 1-149 | [»] | |
1YJW | X-ray | 2.90 | P | 1-149 | [»] | |
2OTJ | X-ray | 2.90 | P | 1-149 | [»] | |
2OTL | X-ray | 2.70 | P | 1-149 | [»] | |
2QA4 | X-ray | 3.00 | P | 1-149 | [»] | |
2QEX | X-ray | 2.90 | P | 1-149 | [»] | |
3CC2 | X-ray | 2.40 | P | 1-149 | [»] | |
3CC4 | X-ray | 2.70 | P | 1-149 | [»] | |
3CC7 | X-ray | 2.70 | P | 1-149 | [»] | |
3CCE | X-ray | 2.75 | P | 1-149 | [»] | |
3CCJ | X-ray | 2.70 | P | 1-149 | [»] | |
3CCL | X-ray | 2.90 | P | 1-149 | [»] | |
3CCM | X-ray | 2.55 | P | 1-149 | [»] | |
3CCQ | X-ray | 2.90 | P | 1-149 | [»] | |
3CCR | X-ray | 3.00 | P | 1-149 | [»] | |
3CCS | X-ray | 2.95 | P | 1-149 | [»] | |
3CCU | X-ray | 2.80 | P | 1-149 | [»] | |
3CCV | X-ray | 2.90 | P | 1-149 | [»] | |
3CD6 | X-ray | 2.75 | P | 1-149 | [»] | |
3CMA | X-ray | 2.80 | P | 1-149 | [»] | |
3CME | X-ray | 2.95 | P | 1-149 | [»] | |
3CPW | X-ray | 2.70 | O | 1-149 | [»] | |
3CXC | X-ray | 3.00 | O | 2-149 | [»] | |
3G4S | X-ray | 3.20 | P | 2-144 | [»] | |
3G6E | X-ray | 2.70 | P | 2-144 | [»] | |
3G71 | X-ray | 2.85 | P | 2-144 | [»] | |
3I55 | X-ray | 3.11 | P | 1-149 | [»] | |
3I56 | X-ray | 2.90 | P | 1-149 | [»] | |
3OW2 | X-ray | 2.70 | O | 2-144 | [»] | |
4ADX | electron microscopy | 6.60 | P | 1-149 | [»] | |
4V9F | X-ray | 2.40 | P | 1-149 | [»] | |
AlphaFoldDBi | P14119 | |||||
SMRi | P14119 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | P14119, 2 interactors |
STRINGi | 272569.rrnAC1594 |
Genome annotation databases
EnsemblBacteriai | AAV46512; AAV46512; rrnAC1594 |
GeneIDi | 40152559 64821833 |
KEGGi | hma:rrnAC1594 |
PATRICi | fig|272569.17.peg.2283 |
Phylogenomic databases
eggNOGi | arCOG04089, Archaea |
HOGENOMi | CLU_083919_1_1_2 |
OMAi | NRVWIDP |
Miscellaneous databases
EvolutionaryTracei | P14119 |
Family and domain databases
CDDi | cd01418, Ribosomal_L19e_A, 1 hit |
Gene3Di | 1.10.1200.60, 1 hit 1.10.1650.10, 1 hit 1.20.5.560, 1 hit |
HAMAPi | MF_01475, Ribosomal_L19e, 1 hit |
InterProi | View protein in InterPro IPR035970, 60S_ribosomal_L19/L19e_sf IPR000196, Ribosomal_L19/L19e IPR023638, Ribosomal_L19/L19e_CS IPR015972, Ribosomal_L19/L19e_dom1 IPR033936, Ribosomal_L19e_A IPR015973, Ribosomal_L19e_dom2 IPR015974, Ribosomal_L19e_dom3 IPR039547, RPL19 |
PANTHERi | PTHR10722, PTHR10722, 1 hit |
Pfami | View protein in Pfam PF01280, Ribosomal_L19e, 1 hit |
SMARTi | View protein in SMART SM01416, Ribosomal_L19e, 1 hit |
SUPFAMi | SSF48140, SSF48140, 1 hit |
PROSITEi | View protein in PROSITE PS00526, RIBOSOMAL_L19E, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RL19E_HALMA | |
Accessioni | P14119Primary (citable) accession number: P14119 Secondary accession number(s): Q5V1U0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1990 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 147 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families