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UniProtKB - P14046 (A1I3_RAT)

Entry version 147 (12 Aug 2020)
Sequence version 1 (01 Apr 1990)
Previous versions | rss
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Protein

Alpha-1-inhibitor 3

Gene

A1i3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protease inhibitor with a wide spectrum of protein targets, which attaches through its thioester function.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Alpha-1-inhibitor 3
Alternative name(s):
Alpha-1-inhibitor 3 variant II
Short name:
Alpha-1-inhibitor III
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:A1i3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...RGDi		1584999, LOC297568

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Add BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000006125 – 1477Alpha-1-inhibitor 3Add BLAST1453

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi48 ↔ 86By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi55N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi247N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi251 ↔ 295By similarity
Disulfide bondi269 ↔ 283By similarity
Glycosylationi301N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi321N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi393N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi468 ↔ 563By similarity
Glycosylationi508N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi595 ↔ 774By similarity
Disulfide bondi643 ↔ 678By similarity
Glycosylationi750N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi777N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi850 ↔ 886By similarity
Glycosylationi872N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi924 ↔ 1324By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki975 ↔ 978Isoglutamyl cysteine thioester (Cys-Gln)
Glycosylationi994N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1082 ↔ 1130By similarity
Glycosylationi1143N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1314N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1355 ↔ 1470By similarity
Glycosylationi1427N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein, Thioester bond

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P14046

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P14046

PRoteomics IDEntifications database

More...PRIDEi		P14046

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		P14046, 13 sites, 2 N-linked glycans (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P14046

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P14046

UniCarbKB; an annotated and curated database of glycan structures

More...UniCarbKBi		P14046

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		P14046, 1 interactor

STRING: functional protein association networks

More...STRINGi		10116.ENSRNOP00000040516

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni601 – 750Bait region (approximate)Add BLAST150

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. [View classification]Curated

Keywords - Domaini

Bait region, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1366, Eukaryota

Database for complete collections of gene phylogenies

More...PhylomeDBi		P14046

Family and domain databases

Conserved Domains Database

More...CDDi		cd02897, A2M_2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 2 hits
2.60.40.690, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR009048, A-macroglobulin_rcpt-bd
IPR036595, A-macroglobulin_rcpt-bd_sf
IPR011625, A2M_N_BRD
IPR041813, A2M_TED
IPR011626, Alpha-macroglobulin_TED
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR001599, Macroglobln_a2
IPR019742, MacrogloblnA2_CS
IPR002890, MG2
IPR041555, MG3
IPR040839, MG4
IPR008930, Terpenoid_cyclase/PrenylTrfase
IPR010916, TonB_box_CS

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00207, A2M, 1 hit
PF07703, A2M_BRD, 1 hit
PF07677, A2M_recep, 1 hit
PF01835, MG2, 1 hit
PF17791, MG3, 1 hit
PF17789, MG4, 1 hit
PF07678, TED_complement, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01360, A2M, 1 hit
SM01359, A2M_N_2, 1 hit
SM01361, A2M_recep, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48239, SSF48239, 1 hit
SSF49410, SSF49410, 1 hit
SSF81296, SSF81296, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00477, ALPHA_2_MACROGLOBULIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

P14046-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKDREAQLC LFSALLAFLP FASLLNGNSK YMVLVPSQLY TETPEKICLH 
        60         70         80         90        100
LYHLNETVTV TASLISQRGT RKLFDELVVD KDLFHCVSFT IPRLPSSEEE 
       110        120        130        140        150
ESLDINIEGA KHKFSERRVV LVKNKESVVF VQTDKPMYKP GQSVKFRVVS 
       160        170        180        190        200
MDKNLHPLNE LFPLAYIEDP KMNRIMQWQD VKTENGLKQL SFSLSAEPIQ 
       210        220        230        240        250
GPYKIVILKQ SGVKEEHSFT VMEFVLPRFG VDVKVPNAIS VYDEIINVTA 
       260        270        280        290        300
CATYTYGKPV PGHVKISLCH GNPTFSSETK SGCKEEDSRL DNNGCSTQEV 
       310        320        330        340        350
NITEFQLKEN YLKMHQAFHV NATVTEEGTG SEFSGSGRIE VERTRNKFLF 
       360        370        380        390        400
LKADSHFRHG IPFFVKVRLV DIKGDPIPNE QVLIKARDAG YTNATTTDQH 
       410        420        430        440        450
GLAKFSIDTN GISDYSLNIK VYHKEESSCI HSSCTAERHA EAHHTAYAVY 
       460        470        480        490        500
SLSKSYIYLD TEAGVLPCNQ IHTVQAHFIL KGQVLGVLQQ IVFHYLVMAQ 
       510        520        530        540        550
GSILQTGNHT HQVEPGESQV QGNFALEIPV EFSMVPVAKM LIYTILPDGE 
       560        570        580        590        600
VIADSVKFQV EKCLRNKVHL SFSPSQSLPA SQTHMRVTAS PQSLCGLRAV 
       610        620        630        640        650
DQSVLLQKPE AELSPSLIYD LPGMQDSNFI ASSNDPFEDE DYCLMYQPIA 
       660        670        680        690        700
REKDVYRYVR ETGLMAFTNL KIKLPTYCNT DYDMVPLAVP AVALDSSTDR 
       710        720        730        740        750
GMYESLPVVA VKSPLPQEPP RKDPPPKDPV IETIRNYFPE TWIWDLVTVN 
       760        770        780        790        800
SSGVTELEMT VPDTITEWKA GALCLSNDTG LGLSSVASFQ AFQPFFVELT 
       810        820        830        840        850
MPYSVIRGEA FTLKATVLNY LPTSLPMAVL LEASPDFTAV PVENNQDSYC 
       860        870        880        890        900
LGANGRHTSS WLVTPKSLGN VNFSVSAEAR QSPGPCGSEV ATVPETGRKD 
       910        920        930        940        950
TVVKVLIVEP EGIKKEHTFS SLLCASDAEL SETLSLLLPP TVVKDSARAH 
       960        970        980        990       1000
FSVMGDILSS AIKNTQNLIQ MPYGCGEQNM VLFAPNIYVL KYLNETQQLT 
      1010       1020       1030       1040       1050
EKIKSKALGY LRAGYQRELN YKHKDGSYSA FGDHNGQGQG NTWLTAFVLK 
      1060       1070       1080       1090       1100
SFAQARAFIF IDESHITDAF TWLSKQQKDS GCFRSSGSLL NNAMKGGVDD 
      1110       1120       1130       1140       1150
EITLSAYITM ALLESSLPDT DPVVSKALSC LESSWENIEQ GGNGSFVYTK 
      1160       1170       1180       1190       1200
ALMAYAFALA GNQEKRNEIL KSLDKEAIKE DNSIHWERPQ KPTKSEGYLY 
      1210       1220       1230       1240       1250
TPQASSAEVE MSAYVVLARL TAQPAPSPED LALSMGTIKW LTKQQNSYGG 
      1260       1270       1280       1290       1300
FSSTQDTVVA LDALSKYGAA TFSKSQKTPS VTVQSSGSFS QKFQVDKSNR 
      1310       1320       1330       1340       1350
LLLQQVSLPY IPGNYTVSVS GEGCVYAQTT LRYNVPLEKQ QPAFALKVQT 
      1360       1370       1380       1390       1400
VPLTCNNPKG QNSFQISLEI SYMGSRPASN MVIADVKMLS GFIPLKPTVK 
      1410       1420       1430       1440       1450
KLERLGHVSR TEVTTNNVLL YLDQVTNQTL SFSFIIQQDI PVKNLQPAIV 
      1460       1470 
KVYDYYETDE VAFAEYSSPC SSDDQNV
Length:1,477
Mass (Da):163,773
Last modified:April 1, 1990 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4DC05367C8385D2B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JUP5A0A0G2JUP5_RAT
Murinoglobulin-1
Mug1 LOC297568
1,450Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2K926A0A0G2K926_RAT
Murinoglobulin-1
LOC297568 Mug1, rCG_29619
1,477Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D4AA52D4AA52_RAT
Murinoglobulin-1
LOC297568 Mug1
1,477Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JUW7A0A0G2JUW7_RAT
Murinoglobulin-1
Mug1 LOC297568
1,487Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D4A6E3D4A6E3_RAT
Murinoglobulin-1
Mug1
1,487Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti677Y → T AA sequence (PubMed:2472396).Curated1
Sequence conflicti1373M → T in AAH98768 (PubMed:2436907).Curated1
Sequence conflicti1406G → E in AAA63494 (PubMed:2436907).Curated1
Sequence conflicti1474D → N in AAA63494 (PubMed:2436907).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
J03552 mRNA Translation: AAA40628.1
M22993 Genomic DNA Translation: AAA79025.1
BC098768 mRNA Translation: AAH98768.1
M28297 mRNA Translation: AAA63493.1
M28298 mRNA Translation: AAA63494.1

Protein sequence database of the Protein Information Resource

More...PIRi		A29952

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03552 mRNA Translation: AAA40628.1
M22993 Genomic DNA Translation: AAA79025.1
BC098768 mRNA Translation: AAH98768.1
M28297 mRNA Translation: AAA63493.1
M28298 mRNA Translation: AAA63494.1
PIRiA29952

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

IntActiP14046, 1 interactor
STRINGi10116.ENSRNOP00000040516

PTM databases

GlyGeniP14046, 13 sites, 2 N-linked glycans (1 site)
iPTMnetiP14046
PhosphoSitePlusiP14046
UniCarbKBiP14046

Proteomic databases

jPOSTiP14046
PaxDbiP14046
PRIDEiP14046

Organism-specific databases

RGDi1584999, LOC297568

Phylogenomic databases

eggNOGiKOG1366, Eukaryota
PhylomeDBiP14046

Miscellaneous databases

Protein Ontology

More...PROi		PR:P14046

Family and domain databases

CDDicd02897, A2M_2, 1 hit
Gene3Di2.60.40.10, 2 hits
2.60.40.690, 1 hit
InterProiView protein in InterPro
IPR009048, A-macroglobulin_rcpt-bd
IPR036595, A-macroglobulin_rcpt-bd_sf
IPR011625, A2M_N_BRD
IPR041813, A2M_TED
IPR011626, Alpha-macroglobulin_TED
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR001599, Macroglobln_a2
IPR019742, MacrogloblnA2_CS
IPR002890, MG2
IPR041555, MG3
IPR040839, MG4
IPR008930, Terpenoid_cyclase/PrenylTrfase
IPR010916, TonB_box_CS
PfamiView protein in Pfam
PF00207, A2M, 1 hit
PF07703, A2M_BRD, 1 hit
PF07677, A2M_recep, 1 hit
PF01835, MG2, 1 hit
PF17791, MG3, 1 hit
PF17789, MG4, 1 hit
PF07678, TED_complement, 1 hit
SMARTiView protein in SMART
SM01360, A2M, 1 hit
SM01359, A2M_N_2, 1 hit
SM01361, A2M_recep, 1 hit
SUPFAMiSSF48239, SSF48239, 1 hit
SSF49410, SSF49410, 1 hit
SSF81296, SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00477, ALPHA_2_MACROGLOBULIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA1I3_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P14046
Secondary accession number(s): Q4G042
, Q63266, Q6LDP2, Q6LDR8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: August 12, 2020
This is version 147 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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