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Entry version 47 (25 May 2022)
Sequence version 1 (01 Jan 1990)
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Protein

Glutamic acid-rich protein

Gene

GARP

Organism
Plasmodium falciparum (isolate FC27 / Papua New Guinea)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glutamic acid-rich protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GARP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate FC27 / Papua New Guinea)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5837 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaSarAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Diseasei

Malaria

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Add BLAST25
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002453826 – 678Glutamic acid-rich proteinAdd BLAST653

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P13816

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...
AlphaFoldDBi
P13816

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati120 – 1221-13
Repeati123 – 1251-23
Repeati126 – 1281-33
Repeati129 – 1311-43
Repeati132 – 1341-53
Repeati135 – 1371-63
Repeati138 – 1401-73
Repeati141 – 1431-83
Repeati144 – 1461-93
Repeati147 – 1491-103
Repeati150 – 1521-113
Repeati153 – 1551-123
Repeati156 – 1581-133
Repeati159 – 1611-143
Repeati162 – 1641-153
Repeati372 – 3762-15
Repeati377 – 3812-25
Repeati382 – 3862-35
Repeati387 – 3912-45
Repeati392 – 3962-55
Repeati397 – 4012-65
Repeati402 – 4062-75
Repeati407 – 4112-85
Repeati412 – 4162-95
Repeati417 – 4213-15
Repeati422 – 4263-25
Repeati427 – 4313-35
Repeati432 – 4363-45
Repeati437 – 4413-55

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni56 – 194DisorderedSequence analysisAdd BLAST139
Regioni120 – 16415 X 3 AA tandem repeats of K-K-[DEHK]Add BLAST45
Regioni225 – 445DisorderedSequence analysisAdd BLAST221
Regioni372 – 4169 X 5 AA tandem repeats of [EGK]-E-H-K-[EKS]Add BLAST45
Regioni417 – 4415 X 5 AA tandem repeats of K-[GAV]-K-[KH]-[DKEH]Add BLAST25
Regioni520 – 678DisorderedSequence analysisAdd BLAST159

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi56 – 82Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi83 – 111Polar residuesSequence analysisAdd BLAST29
Compositional biasi145 – 161Basic residuesSequence analysisAdd BLAST17
Compositional biasi232 – 344Basic and acidic residuesSequence analysisAdd BLAST113
Compositional biasi346 – 360Polar residuesSequence analysisAdd BLAST15
Compositional biasi369 – 410Basic and acidic residuesSequence analysisAdd BLAST42
Compositional biasi411 – 440Basic residuesSequence analysisAdd BLAST30
Compositional biasi528 – 562Basic and acidic residuesSequence analysisAdd BLAST35
Compositional biasi563 – 662Acidic residuesSequence analysisAdd BLAST100

Keywords - Domaini

Repeat, Signal

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P13816-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNVLFLSYNI CILFFVVCTL NFSTKCFSNG LLKNQNILNK SFDSITGRLL
60 70 80 90 100
NETELEKNKD DNSKSETLLK EEKDEKDDVP TTSNDNLKNA HNNNEISSST
110 120 130 140 150
DPTNIINVND KDNENSVDKK KDKKEKKHKK DKKEKKEKKD KKEKKDKKEK
160 170 180 190 200
KHKKEKKHKK DKKKKENSEV MSLYKTGQHK PKNATEHGEE NLDEEMVSEI
210 220 230 240 250
NNNAQGGLLL SSPYQYREQG GCGIISSVHE TSNDTKDNDK ENISEDKKED
260 270 280 290 300
HQQEEMLKTL DKKERKQKEK EMKEQEKIEK KKKKQEEKEK KKQEKERKKQ
310 320 330 340 350
EKKERKQKEK EMKKQKKIEK ERKKKEEKEK KKKKHDKENE ETMQQPDQTS
360 370 380 390 400
EETNNEIMVP LPSPLTDVTT PEEHKEGEHK EEEHKEGEHK EGEHKEEEHK
410 420 430 440 450
EEEHKKEEHK SKEHKSKGKK DKGKKDKGKH KKAKKEKVKK HVVKNVIEDE
460 470 480 490 500
DKDGVEIINL EDKEACEEQH ITVESRPLSQ PQCKLIDEPE QLTLMDKSKV
510 520 530 540 550
EEKNLSIQEQ LIGTIGRVNV VPRRDNHKKK MAKIEEAELQ KQKHVDKEED
560 570 580 590 600
KKEESKEVQE ESKEVQEDEE EVEEDEEEEE EEEEEEEEEE EEEEEEEEEE
610 620 630 640 650
EEEEEDEDEE DEDDAEEDED DAEEDEDDAE EDDDEEDDDE EDDDEDEDED
660 670
EEDEEEEEEE EEESEKKIKR NLRKNAKI
Length:678
Mass (Da):80,551
Last modified:January 1, 1990 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2A8F85606496EA9E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J03998 Genomic DNA Translation: AAA29605.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A54514

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03998 Genomic DNA Translation: AAA29605.1
PIRiA54514

3D structure databases

AlphaFoldDBiP13816
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Proteomic databases

PRIDEiP13816

Family and domain databases

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGARP_PLAFF
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P13816
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: May 25, 2022
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
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