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Protein

Puromycin N-acetyltransferase

Gene

pac

Organism
Streptomyces alboniger
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Detoxification of puromycin.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processAntibiotic resistance

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-13983

Names & Taxonomyi

Protein namesi
Recommended name:
Puromycin N-acetyltransferase (EC:2.3.-.-)
Gene namesi
Name:pac
OrganismiStreptomyces alboniger
Taxonomic identifieri132473 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000685781 – 199Puromycin N-acetyltransferaseAdd BLAST199

Structurei

3D structure databases

ProteinModelPortaliP13249
SMRiP13249
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 198N-acetyltransferasePROSITE-ProRule annotationAdd BLAST193

Phylogenomic databases

KOiK12632

Family and domain databases

InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR000182 GNAT_dom
PfamiView protein in Pfam
PF00583 Acetyltransf_1, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
PROSITEiView protein in PROSITE
PS51186 GNAT, 1 hit

Sequencei

Sequence statusi: Complete.

P13249-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYKPTVRL ATRDDVPRAV RTLAAAFADY PATRHTVDPD RHIERVTELQ
60 70 80 90 100
ELFLTRVGLD IGKVWVADDG AAVAVWTTPE SVEAGAVFAE IGPRMAELSG
110 120 130 140 150
SRLAAQQQME GLLAPHRPKE PAWFLATVGV SPDHQGKGLG SAVVLPGVEA
160 170 180 190
AERAGVPAFL ETSAPRNLPF YERLGFTVTA DVEVPEGPRT WCMTRKPGA
Length:199
Mass (Da):21,496
Last modified:February 1, 1996 - v2
Checksum:iBEDA36E20304DA35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M25346 Genomic DNA Translation: AAA64928.1
PIRiJU0052

Genome annotation databases

KEGGiag:AAA64928

Similar proteinsi

Entry informationi

Entry nameiPUAC_STRAD
AccessioniPrimary (citable) accession number: P13249
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 74 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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