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Entry version 164 (12 Aug 2020)
Sequence version 3 (23 Jan 2007)
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Protein

Aspartate aminotransferase, cytoplasmic

Gene

Got1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.6 Publications

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pyridoxal 5'-phosphate

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by L-aspartate.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=22.2 mM for L-cysteine1 Publication
  2. KM=0.06 mM for 2-oxoglutarate1 Publication

    pH dependencei

    Optimum pH is 9.7.1 Publication

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei39Aspartate; via amide nitrogenBy similarity1
    Binding sitei141AspartateBy similarity1
    Binding sitei195AspartateBy similarity1
    Binding sitei387AspartateBy similarity1

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionAminotransferase, Transferase
    Biological processAmino-acid biosynthesis
    LigandPyridoxal phosphate

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    MetaCyc:MONOMER-12468

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-RNO-70263, Gluconeogenesis
    R-RNO-8963693, Aspartate and asparagine metabolism

    SABIO-RK: Biochemical Reaction Kinetics Database

    More...
    SABIO-RKi
    P13221

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Aspartate aminotransferase, cytoplasmic (EC:2.6.1.1, EC:2.6.1.3)
    Short name:
    cAspAT
    Alternative name(s):
    Cysteine aminotransferase, cytoplasmic
    Cysteine transaminase, cytoplasmic
    Short name:
    cCAT
    Glutamate oxaloacetate transaminase 1
    Transaminase A
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:Got1
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

    Organism-specific databases

    Rat genome database

    More...
    RGDi
    2721, Got1

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Cytoplasm

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001238831 – 413Aspartate aminotransferase, cytoplasmicAdd BLAST413

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei46PhosphoserineCombined sources1
    Modified residuei149PhosphoserineCombined sources1
    Modified residuei259N6-(pyridoxal phosphate)lysine1

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    jPOST - Japan Proteome Standard Repository/Database

    More...
    jPOSTi
    P13221

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    P13221

    PRoteomics IDEntifications database

    More...
    PRIDEi
    P13221

    2D gel databases

    The World-2DPAGE database

    More...
    World-2DPAGEi
    0004:P13221

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    P13221

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    P13221

    SwissPalm database of S-palmitoylation events

    More...
    SwissPalmi
    P13221

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed in liver and kidney.1 Publication

    <p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    In liver and kidney, by glucocorticod hormones. Levels in the liver also increase 2-fold on animals fed on a high protein diet or during fasting. By hypoxia during cerebral ischemia.4 Publications

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSRNOG00000016356, Expressed in heart and 21 other tissues

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    P13221, RN

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Homodimer.

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGRID)

    More...
    BioGRIDi
    246568, 1 interactor

    Protein interaction database and analysis system

    More...
    IntActi
    P13221, 1 interactor

    STRING: functional protein association networks

    More...
    STRINGi
    10116.ENSRNOP00000022309

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    P13221

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG1412, Eukaryota

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00950000183082

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_032440_1_2_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    P13221

    KEGG Orthology (KO)

    More...
    KOi
    K14454

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    IRSYHYW

    Database of Orthologous Groups

    More...
    OrthoDBi
    1104596at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    P13221

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF314089

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    3.40.640.10, 1 hit
    3.90.1150.10, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR004839, Aminotransferase_I/II
    IPR000796, Asp_trans
    IPR004838, NHTrfase_class1_PyrdxlP-BS
    IPR015424, PyrdxlP-dep_Trfase
    IPR015422, PyrdxlP-dep_Trfase_dom1
    IPR015421, PyrdxlP-dep_Trfase_major

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR11879, PTHR11879, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00155, Aminotran_1_2, 1 hit

    Protein Motif fingerprint database; a protein domain database

    More...
    PRINTSi
    PR00799, TRANSAMINASE

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF53383, SSF53383, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS00105, AA_TRANSFER_CLASS_1, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    P13221-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MAPPSFFAQV PQAPPVLVFK LIADFRDDPD PRKVNLGVGA YRTDDSQPWV
    60 70 80 90 100
    LPVVRKVEQK IANDHSLNHE YLPILGLAEF RSCASQLVLG DNSPALRENR
    110 120 130 140 150
    VGGVQSLGGT GALRIGADFL GRWYNGTDNK NTPVYVSSPT WENHNGVFSA
    160 170 180 190 200
    AGFKDIRSYR YWDAEKRGLD LQGFLNDLEN APEFSIFVLH ACAHNPTGTD
    210 220 230 240 250
    PTEEEWKQIA AVMKRRFLFP FFDSAYQGFA SGDLEKDAWA IRYFVSEGFE
    260 270 280 290 300
    LFCAQSFSKN FGLYNERVGN LTVVGKEHDS VLRVLSQMEK IVRITWSNPP
    310 320 330 340 350
    AQGARIVATT LSNPELFKEW KGNVKTMADR ILTMRSELRA RLEALKTPGT
    360 370 380 390 400
    WSHITEQIGM FSFTGLNPKQ VEYLVNEKHI YLMPSGRINM CGLTTKNLDY
    410
    VATSINEAVT KFQ
    Length:413
    Mass (Da):46,429
    Last modified:January 23, 2007 - v3
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA9425BF05AC24C08
    GO

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti55R → T in AAA40769 (PubMed:3182856).Curated1
    Sequence conflicti100R → G in AAA40769 (PubMed:3182856).Curated1
    Sequence conflicti109G → A in AAA40769 (PubMed:3182856).Curated1
    Sequence conflicti121G → A in AAA40769 (PubMed:3182856).Curated1
    Sequence conflicti125N → I in BAA00183 (PubMed:3053674).Curated1
    Sequence conflicti254A → P in AAA40769 (PubMed:3182856).Curated1
    Sequence conflicti366L → F in BAA00183 (PubMed:3053674).Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    J04171 mRNA Translation: AAA40769.1
    D00252 mRNA Translation: BAA00183.1
    BC061877 mRNA Translation: AAH61877.1
    J05263 Genomic DNA Translation: AAA40842.1

    Protein sequence database of the Protein Information Resource

    More...
    PIRi
    I55325
    JT0439

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_036703.2, NM_012571.2

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENSRNOT00000022309; ENSRNOP00000022309; ENSRNOG00000016356

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    24401

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    rno:24401

    UCSC genome browser

    More...
    UCSCi
    RGD:2721, rat

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    J04171 mRNA Translation: AAA40769.1
    D00252 mRNA Translation: BAA00183.1
    BC061877 mRNA Translation: AAH61877.1
    J05263 Genomic DNA Translation: AAA40842.1
    PIRiI55325
    JT0439
    RefSeqiNP_036703.2, NM_012571.2

    3D structure databases

    SMRiP13221
    ModBaseiSearch...

    Protein-protein interaction databases

    BioGRIDi246568, 1 interactor
    IntActiP13221, 1 interactor
    STRINGi10116.ENSRNOP00000022309

    PTM databases

    iPTMnetiP13221
    PhosphoSitePlusiP13221
    SwissPalmiP13221

    2D gel databases

    World-2DPAGEi0004:P13221

    Proteomic databases

    jPOSTiP13221
    PaxDbiP13221
    PRIDEiP13221

    Genome annotation databases

    EnsembliENSRNOT00000022309; ENSRNOP00000022309; ENSRNOG00000016356
    GeneIDi24401
    KEGGirno:24401
    UCSCiRGD:2721, rat

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    2805
    RGDi2721, Got1

    Phylogenomic databases

    eggNOGiKOG1412, Eukaryota
    GeneTreeiENSGT00950000183082
    HOGENOMiCLU_032440_1_2_1
    InParanoidiP13221
    KOiK14454
    OMAiIRSYHYW
    OrthoDBi1104596at2759
    PhylomeDBiP13221
    TreeFamiTF314089

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-12468
    ReactomeiR-RNO-70263, Gluconeogenesis
    R-RNO-8963693, Aspartate and asparagine metabolism
    SABIO-RKiP13221

    Miscellaneous databases

    Protein Ontology

    More...
    PROi
    PR:P13221

    Gene expression databases

    BgeeiENSRNOG00000016356, Expressed in heart and 21 other tissues
    GenevisibleiP13221, RN

    Family and domain databases

    Gene3Di3.40.640.10, 1 hit
    3.90.1150.10, 1 hit
    InterProiView protein in InterPro
    IPR004839, Aminotransferase_I/II
    IPR000796, Asp_trans
    IPR004838, NHTrfase_class1_PyrdxlP-BS
    IPR015424, PyrdxlP-dep_Trfase
    IPR015422, PyrdxlP-dep_Trfase_dom1
    IPR015421, PyrdxlP-dep_Trfase_major
    PANTHERiPTHR11879, PTHR11879, 1 hit
    PfamiView protein in Pfam
    PF00155, Aminotran_1_2, 1 hit
    PRINTSiPR00799, TRANSAMINASE
    SUPFAMiSSF53383, SSF53383, 1 hit
    PROSITEiView protein in PROSITE
    PS00105, AA_TRANSFER_CLASS_1, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAATC_RAT
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P13221
    Secondary accession number(s): Q64570, Q6P721
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
    Last sequence update: January 23, 2007
    Last modified: August 12, 2020
    This is version 164 of the entry and version 3 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
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