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Protein

DNA-binding protein 7d

Gene

Saci_0064

Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature.By similarity

Miscellaneous

Sac7a and Sac7b are truncated versions of the Sac7d protein, most likely resulting from post-translational processing, or degradation during isolation.1 Publication

pH dependencei

Highly stable from pH 0 to pH 12.1 Publication

Temperature dependencei

Hyperthermostable.1 Publication

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-binding protein 7dCurated
Alternative name(s):
7 kDa DNA-binding protein d
Sac7d
Cleaved into the following 2 chains:
Alternative name(s):
7 kDa DNA-binding protein a
Sac7a
Alternative name(s):
7 kDa DNA-binding protein b
Sac7b
Gene namesi
Ordered Locus Names:Saci_0064
OrganismiSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Taxonomic identifieri330779 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001018 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved2 Publications
ChainiPRO_00000072482 – 65DNA-binding protein 7dAdd BLAST64
ChainiPRO_00000072492 – 62DNA-binding protein 7aAdd BLAST61
ChainiPRO_00000072502 – 59DNA-binding protein 7bAdd BLAST58

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei5N6-methyllysine; partial1 Publication1
Modified residuei7N6-methyllysine; partial1 Publication1

Post-translational modificationi

Lys-5 was 70% monomethylated in form 7a, 25% in form 7b, and 20% in form 7d. Lys-7 was 50% monomethylated in form 7a, 40% in form 7b, and 50% in form 7d.1 Publication

Keywords - PTMi

Methylation

PTM databases

iPTMnetiP13123

Interactioni

Subunit structurei

Monomer.1 Publication

Protein-protein interaction databases

STRINGi330779.Saci_0064

Structurei

Secondary structure

166
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP13123
SMRiP13123
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP13123

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG05888 Archaea
ENOG410YVM7 LUCA
HOGENOMiHOG000270553
KOiK16640
OMAiMATKIKF
OrthoDBiPOG093Z0NLN

Family and domain databases

InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR003212 DNA-bd_7kDa_arc
PfamiView protein in Pfam
PF02294 7kD_DNA_binding, 1 hit
PIRSFiPIRSF036912 Sac7, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD010328 7kDa_DNA_bd_arc, 1 hit
SUPFAMiSSF54160 SSF54160, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P13123-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVKVKFKYKG EEKEVDTSKI KKVWRVGKMV SFTYDDNGKT GRGAVSEKDA
60
PKELLDMLAR AEREKK
Length:66
Mass (Da):7,609
Last modified:January 23, 2007 - v3
Checksum:iBFF84F058C2DDA97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M87569 Genomic DNA Translation: AAA80315.1
CP000077 Genomic DNA Translation: AAY79492.1
PIRiA27749
RefSeqiWP_011276993.1, NC_007181.1

Genome annotation databases

EnsemblBacteriaiAAY79492; AAY79492; Saci_0064
GeneIDi3473894
KEGGisai:Saci_0064
PATRICifig|330779.12.peg.59

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M87569 Genomic DNA Translation: AAA80315.1
CP000077 Genomic DNA Translation: AAY79492.1
PIRiA27749
RefSeqiWP_011276993.1, NC_007181.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AZPX-ray1.60A1-66[»]
1AZQX-ray1.94A1-66[»]
1BF4X-ray1.60A4-66[»]
1CA5X-ray2.20A1-66[»]
1CA6X-ray2.20A1-66[»]
1SAPNMR-A1-66[»]
1WD0X-ray1.90A1-66[»]
1WD1X-ray2.20A1-66[»]
1WTOX-ray1.50A1-66[»]
1WTPX-ray1.90A/B1-66[»]
1WTQX-ray1.70A1-66[»]
1WTRX-ray1.80A1-66[»]
1WTVX-ray1.60A1-66[»]
1WTWX-ray2.20A1-66[»]
1WTXX-ray2.20A1-66[»]
1WVLX-ray2.60A/B1-66[»]
1XX8NMR-A1-66[»]
1XYIX-ray1.45A1-66[»]
2XIWX-ray1.50A/B2-66[»]
4CJ1X-ray1.63B2-62[»]
4CJ2X-ray1.50C/D2-66[»]
ProteinModelPortaliP13123
SMRiP13123
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi330779.Saci_0064

PTM databases

iPTMnetiP13123

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY79492; AAY79492; Saci_0064
GeneIDi3473894
KEGGisai:Saci_0064
PATRICifig|330779.12.peg.59

Phylogenomic databases

eggNOGiarCOG05888 Archaea
ENOG410YVM7 LUCA
HOGENOMiHOG000270553
KOiK16640
OMAiMATKIKF
OrthoDBiPOG093Z0NLN

Miscellaneous databases

EvolutionaryTraceiP13123

Family and domain databases

InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR003212 DNA-bd_7kDa_arc
PfamiView protein in Pfam
PF02294 7kD_DNA_binding, 1 hit
PIRSFiPIRSF036912 Sac7, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD010328 7kDa_DNA_bd_arc, 1 hit
SUPFAMiSSF54160 SSF54160, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDN7D_SULAC
AccessioniPrimary (citable) accession number: P13123
Secondary accession number(s): Q4JCI7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 23, 2007
Last modified: February 28, 2018
This is version 125 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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