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Entry version 185 (02 Jun 2021)
Sequence version 3 (24 Oct 2003)
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Protein

Protein grainyhead

Gene

grh

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds a CNS-specific regulatory element of the Dopa decarboxylase (Ddc) gene. Also interacts with sequences adjacent to other transcription units, including Ultrabithorax (Ubx) and engrailed (en). Activity in vivo may be required only at high levels transiently to activate the expression of Ddc in the CNS.

2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
P13002

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein grainyhead
Alternative name(s):
DNA-binding protein ELF-1
Element I-binding activity
Protein grainy-head
Transcription factor NTF-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:grh
Synonyms:elf1
ORF Names:CG5058
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0259211, grh

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000869521 – 1333Protein grainyheadAdd BLAST1333

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P13002

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Restricted, during embryogenesis, to tissues derived from ectoderm, predominantly the central nervous system (CNS) and the epidermis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0259211, Expressed in embryo and 47 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P13002, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P13002, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
62723, 38 interactors

Database of interacting proteins

More...
DIPi
DIP-59591N

Protein interaction database and analysis system

More...
IntActi
P13002, 12 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0288984

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P13002

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini899 – 1125Grh/CP2 DBPROSITE-ProRule annotationAdd BLAST227

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni52 – 93DisorderedSequence analysisAdd BLAST42
Regioni439 – 598DisorderedSequence analysisAdd BLAST160
Regioni617 – 655DisorderedSequence analysisAdd BLAST39
Regioni727 – 784DisorderedSequence analysisAdd BLAST58
Regioni853 – 885DisorderedSequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi439 – 491Polar residuesSequence analysisAdd BLAST53
Compositional biasi499 – 520Polar residuesSequence analysisAdd BLAST22
Compositional biasi564 – 598Polar residuesSequence analysisAdd BLAST35
Compositional biasi735 – 781Polar residuesSequence analysisAdd BLAST47
Compositional biasi853 – 880Polar residuesSequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the grh/CP2 family. Grainyhead subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4091, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P13002

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P13002

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007604, CP2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04516, CP2, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51968, GRH_CP2_DB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (7+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 7 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: Additional isoforms seem to exist.

This entry has 7 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform JImported (identifier: P13002-6) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSTSTATTSV ITSNELSLSG HAHGHGHAHQ LHQHTHSRLG VGVGVGILSD
60 70 80 90 100
ASLSPIQQGS GGHSGGGNTN SSPLAPNGVP LLTTMHRSPD SPQPELATMT
110 120 130 140 150
NVNVLDLHTD NSKLYDKEAV FIYETPKVVM PADGGGGNNS DEGHAIDARI
160 170 180 190 200
AAQMGNQAQQ QQQQQQQTEH QPLAKIEFDE NQIIRVVGPN GEQQQIISRE
210 220 230 240 250
IINGEHHILS RNEAGEHILT RIVSDPSKLM PNDNAVATAM YNQAQKMNND
260 270 280 290 300
HGQAVYQTSP LPLDASVLHY SGGNDSNVIK TEADIYEDHK KHAAAAAAAA
310 320 330 340 350
GGGSIIYTTS DPNGVNVKQL PHLTVPQKLD PDLYQADKHI DLIYNDGSKT
360 370 380 390 400
VIYSTTDQKS LEIYSGGDIG SLVSDGQVVV QAGLPYATTT GAGGQPVYIV
410 420 430 440 450
ADGALPAGVE EHLQSGKLNG QTTPIDVSGL SQNEIQGFLL GSHPSSSATV
460 470 480 490 500
STTGVVSTTT ISHHQQQQQQ QQQQQQQQQQ QHQQQQQHPG DIVSAAGVGS
510 520 530 540 550
TGSIVSSAAQ QQQQQQLISI KREPEDLRKD PKNGNIAGAA TANGPGSVIT
560 570 580 590 600
QKILHVDAPT ASEADRPSTP SSSINSTENT ESDSQSVSGS ESGSPGARTT
610 620 630 640 650
ATLEMYATTG GTQIYLQTSH PSTASGAGGG AGPAGAAGGG GVSMQAQSPS
660 670 680 690 700
PGPYITANDY GMYTASRLPP GPPPTSTTTF IAEPSYYREY FAPDGQGGYV
710 720 730 740 750
PASTRSLYGD VDVSVSQPGG VVTYEGRFAG SVPPPATTTV LTSVHHHQQQ
760 770 780 790 800
QQQQQQHQQQ QQQQQHHQQQ QHHSQDGKSN GGATPLYAKA ITAAGLTVDL
810 820 830 840 850
PSPDSGIGTD AITPRDQTNI QQSFDYTELC QPGTLIDANG SIPVSVNSIQ
860 870 880 890 900
QRTAVHGSQN SPTTSLVDTS TNGSTRSRPW HDFGRQNDAD KIQIPKIFTN
910 920 930 940 950
VGFRYHLESP ISSSQRREDD RITYINKGQF YGITLEYVHD AEKPIKNTTV
960 970 980 990 1000
KSVIMLMFRE EKSPEDEIKA WQFWHSRQHS VKQRILDADT KNSVGLVGCI
1010 1020 1030 1040 1050
EEVSHNAIAV YWNPLESSAK INIAVQCLST DFSSQKGVKG LPLHVQIDTF
1060 1070 1080 1090 1100
EDPRDTAVFH RGYCQIKVFC DKGAERKTRD EERRAAKRKM TATGRKKLDE
1110 1120 1130 1140 1150
LYHPVTDRSE FYGMQDFAKP PVLFSPAEDM EKVGQLGIGA ATGMTFNPLS
1160 1170 1180 1190 1200
NGNSNSNSHS SLQSFYGHET DSPDLKGASP FLLHGQKVAT PTLKFHNHFP
1210 1220 1230 1240 1250
PDMQTDKKDH ILDQNMLTST PLTDFGPPMK RGRMTPPTSE RVMLYVRQEN
1260 1270 1280 1290 1300
EEVYTPLHVV PPTTIGLLNA IENKYKISTT SINNIYRTNK KGITAKIDDD
1310 1320 1330
MISFYCNEDI FLLEVQQIED DLYDVTLTEL PNQ
Length:1,333
Mass (Da):143,915
Last modified:October 24, 2003 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i71EBE69DAE6D071C
GO
Isoform I (identifier: P13002-1) [UniParc]FASTAAdd to basket
Also known as: AImported

The sequence of this isoform differs from the canonical sequence as follows:
     553-822: Missing.

Show »
Length:1,063
Mass (Da):116,069
Checksum:iB9D2E6B869C9CC16
GO
Isoform HImported (identifier: P13002-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     553-822: Missing.
     1133-1163: Missing.

Show »
Length:1,032
Mass (Da):113,026
Checksum:iD668D1B82CD0D6A3
GO
Isoform LImported (identifier: P13002-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1133-1163: Missing.

Show »
Length:1,302
Mass (Da):140,871
Checksum:iF46825F30B9A84A7
GO
Isoform OImported (identifier: P13002-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-604: Missing.
     1133-1163: Missing.

Show »
Length:698
Mass (Da):77,376
Checksum:i27A80C6307FC7FF1
GO
Isoform NImported (identifier: P13002-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-604: Missing.

Show »
Length:729
Mass (Da):80,419
Checksum:i688F2D219E33EDB6
GO
Isoform KImported (identifier: P13002-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2-414: STSTATTSVI...LPAGVEEHLQ → QEATSTTNYA...NGSPGADLPW
     553-822: Missing.

Show »
Length:784
Mass (Da):87,559
Checksum:iC307F1AA5A9521B4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4LFT7A0A0B4LFT7_DROME
Grainy head, isoform P
grh BcDNA:LD38807, CG30111, CG5058, Dmel\CG42311, DREB
1,063Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4K7F6A0A0B4K7F6_DROME
Grainy head, isoform O
grh BcDNA:LD38807, CG30111, CG5058, Dmel\CG42311, DREB
698Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti262P → R in CAA33692 (PubMed:2792757).Curated1
Sequence conflicti415S → R in CAA22954 (PubMed:10731137).Curated1
Sequence conflicti504I → V in AAR99118 (Ref. 5) Curated1
Sequence conflicti610G → C in AAK93490 (PubMed:12537569).Curated1
Sequence conflicti969K → R in AAR99118 (Ref. 5) Curated1
Sequence conflicti999C → V in CAA33692 (PubMed:2792757).Curated1
Sequence conflicti1006 – 1007NA → KS in CAA33692 (PubMed:2792757).Curated2
Sequence conflicti1089K → E in AAR99118 (Ref. 5) Curated1
Sequence conflicti1233R → S in AAK93490 (PubMed:12537569).Curated1
Sequence conflicti1322L → R in AAO24937 (PubMed:12537569).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0086091 – 604Missing in isoform O and isoform N. 1 PublicationAdd BLAST604
Alternative sequenceiVSP_0581602 – 414STSTA…EEHLQ → QEATSTTNYALSYTDWMSEP RRGFSLDSLHAGHVESDPQQ QQHHQQLLHHYYSPGDQVKD QGLVLPLNHQQDHHGHHLTA AGLMQAVAAEIQLNEDQDQL HPNANQNSPYPIYSYYRSEG ERANNGSPGADLPW in isoform K. CuratedAdd BLAST413
Alternative sequenceiVSP_008611553 – 822Missing in isoform H, isoform I and isoform K. 3 PublicationsAdd BLAST270
Alternative sequenceiVSP_0086121133 – 1163Missing in isoform H, isoform L and isoform O. 2 PublicationsAdd BLAST31

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X15657 mRNA Translation: CAA33692.1
AE013599 Genomic DNA Translation: AAF57782.3
AE013599 Genomic DNA Translation: AAF57784.3
AE013599 Genomic DNA Translation: AAM68467.2
AE013599 Genomic DNA Translation: AAM68468.2
AE013599 Genomic DNA Translation: AAM68470.2
AE013599 Genomic DNA Translation: AAM68472.2
AY052066 mRNA Translation: AAK93490.1
BT001414 mRNA Translation: AAN71169.1
BT003182 mRNA Translation: AAO24937.1
BT029431 mRNA Translation: ABK57088.1
AL035312 Genomic DNA Translation: CAA22954.1
BT011460 mRNA Translation: AAR99118.1

Protein sequence database of the Protein Information Resource

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PIRi
S06206

NCBI Reference Sequences

More...
RefSeqi
NP_001286551.1, NM_001299622.1 [P13002-1]
NP_476842.2, NM_057494.4 [P13002-1]
NP_476843.2, NM_057495.4 [P13002-2]
NP_476844.2, NM_057496.5 [P13002-3]
NP_476845.2, NM_057497.4 [P13002-6]
NP_725723.2, NM_166250.4 [P13002-8]
NP_725725.1, NM_166252.3 [P13002-4]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0299705; FBpp0288983; FBgn0259211 [P13002-1]
FBtr0299706; FBpp0288984; FBgn0259211 [P13002-6]
FBtr0299707; FBpp0288985; FBgn0259211 [P13002-8]
FBtr0300538; FBpp0289765; FBgn0259211 [P13002-2]
FBtr0300539; FBpp0289766; FBgn0259211 [P13002-3]
FBtr0300541; FBpp0289768; FBgn0259211 [P13002-4]
FBtr0306625; FBpp0297580; FBgn0259211 [P13002-5]
FBtr0345791; FBpp0311781; FBgn0259211 [P13002-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
37038

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG42311

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15657 mRNA Translation: CAA33692.1
AE013599 Genomic DNA Translation: AAF57782.3
AE013599 Genomic DNA Translation: AAF57784.3
AE013599 Genomic DNA Translation: AAM68467.2
AE013599 Genomic DNA Translation: AAM68468.2
AE013599 Genomic DNA Translation: AAM68470.2
AE013599 Genomic DNA Translation: AAM68472.2
AY052066 mRNA Translation: AAK93490.1
BT001414 mRNA Translation: AAN71169.1
BT003182 mRNA Translation: AAO24937.1
BT029431 mRNA Translation: ABK57088.1
AL035312 Genomic DNA Translation: CAA22954.1
BT011460 mRNA Translation: AAR99118.1
PIRiS06206
RefSeqiNP_001286551.1, NM_001299622.1 [P13002-1]
NP_476842.2, NM_057494.4 [P13002-1]
NP_476843.2, NM_057495.4 [P13002-2]
NP_476844.2, NM_057496.5 [P13002-3]
NP_476845.2, NM_057497.4 [P13002-6]
NP_725723.2, NM_166250.4 [P13002-8]
NP_725725.1, NM_166252.3 [P13002-4]

3D structure databases

SMRiP13002
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi62723, 38 interactors
DIPiDIP-59591N
IntActiP13002, 12 interactors
STRINGi7227.FBpp0288984

Proteomic databases

PaxDbiP13002

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
37038

Genome annotation databases

EnsemblMetazoaiFBtr0299705; FBpp0288983; FBgn0259211 [P13002-1]
FBtr0299706; FBpp0288984; FBgn0259211 [P13002-6]
FBtr0299707; FBpp0288985; FBgn0259211 [P13002-8]
FBtr0300538; FBpp0289765; FBgn0259211 [P13002-2]
FBtr0300539; FBpp0289766; FBgn0259211 [P13002-3]
FBtr0300541; FBpp0289768; FBgn0259211 [P13002-4]
FBtr0306625; FBpp0297580; FBgn0259211 [P13002-5]
FBtr0345791; FBpp0311781; FBgn0259211 [P13002-1]
GeneIDi37038
KEGGidme:Dmel_CG42311

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
37038
FlyBaseiFBgn0259211, grh

Phylogenomic databases

eggNOGiKOG4091, Eukaryota
InParanoidiP13002
PhylomeDBiP13002

Enzyme and pathway databases

SignaLinkiP13002

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
37038, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
37038

Protein Ontology

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PROi
PR:P13002

Gene expression databases

BgeeiFBgn0259211, Expressed in embryo and 47 other tissues
ExpressionAtlasiP13002, baseline and differential
GenevisibleiP13002, DM

Family and domain databases

InterProiView protein in InterPro
IPR007604, CP2
PfamiView protein in Pfam
PF04516, CP2, 1 hit
PROSITEiView protein in PROSITE
PS51968, GRH_CP2_DB, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiELF1_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P13002
Secondary accession number(s): A0JQ61
, A1ZB05, Q6NN37, Q86PE1, Q8MMA8, Q8MMB0, Q8MMB1, Q960H2, Q9TYG4, Q9V889, Q9V890, Q9V891
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: October 24, 2003
Last modified: June 2, 2021
This is version 185 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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