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Entry version 133 (02 Jun 2021)
Sequence version 2 (01 Nov 1997)
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Protein

Caldesmon

Gene

CALD1

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding, Calmodulin-binding, Muscle protein

Enzyme and pathway databases

SABIO-RK: Biochemical Reaction Kinetics Database

More...
SABIO-RKi
P12957

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Caldesmon
Short name:
CDM
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CALD1
Synonyms:CAD
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000539 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000892871 – 771CaldesmonAdd BLAST771

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei27Phosphotyrosine1 Publication1
Modified residuei597Phosphoserine; by CDK11 Publication1
Modified residuei640Phosphotyrosine1 Publication1
Modified residuei682Phosphoserine; by CDK11 Publication1
Modified residuei688Phosphothreonine; by CDK11 Publication1
Modified residuei711Phosphothreonine; by CDK11 Publication1
Modified residuei717Phosphoserine; by CDK11 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated in non-muscle cells. Phosphorylation by CDK1 during mitosis causes caldesmon to dissociate from microfilaments. Phosphorylation reduces caldesmon binding to actin, myosin, and calmodulin as well as its inhibition of actomyosin ATPase activity. Phosphorylation also occurs in both quiescent and dividing smooth muscle cells with similar effects on the interaction with actin and calmodulin and on microfilaments reorganization (By similarity).By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P12957

PRoteomics IDEntifications database

More...
PRIDEi
P12957

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P12957

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

High-molecular-weight caldesmon (h-caldesmon) is predominantly expressed in smooth muscles, whereas low-molecular-weight caldesmon (l-caldesmon) is widely distributed in non-muscle tissues and cells. Not expressed in skeletal muscle or heart.

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9031.ENSGALP00000021314

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Biological Magnetic Resonance Data Bank

More...
BMRBi
P12957

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati251 – 2651Add BLAST15
Repeati266 – 2782Add BLAST13
Repeati279 – 2913Add BLAST13
Repeati294 – 3064Add BLAST13
Repeati309 – 3215Add BLAST13
Repeati324 – 3366Add BLAST13
Repeati337 – 3497Add BLAST13
Repeati350 – 3628Add BLAST13
Repeati363 – 3759Add BLAST13
Repeati378 – 39010Add BLAST13

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni23 – 91DisorderedSequence analysisAdd BLAST69
Regioni26 – 199Myosin and calmodulin-bindingAdd BLAST174
Regioni104 – 599DisorderedSequence analysisAdd BLAST496
Regioni251 – 39010 X 13 AA approximate tandem repeatsAdd BLAST140
Regioni523 – 580Tropomyosin-bindingSequence analysisAdd BLAST58
Regioni612 – 644Strong actin-bindingAdd BLAST33
Regioni622 – 632Tropomyosin-bindingSequence analysisAdd BLAST11
Regioni674 – 680Calmodulin-binding7
Regioni676 – 771DisorderedSequence analysisAdd BLAST96
Regioni726 – 752Weak actin-bindingAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi23 – 62Basic and acidic residuesSequence analysisAdd BLAST40
Compositional biasi77 – 91Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi131 – 161Basic and acidic residuesSequence analysisAdd BLAST31
Compositional biasi169 – 217Basic and acidic residuesSequence analysisAdd BLAST49
Compositional biasi220 – 234Polar residuesSequence analysisAdd BLAST15
Compositional biasi237 – 487Basic and acidic residuesSequence analysisAdd BLAST251
Compositional biasi508 – 599Basic and acidic residuesSequence analysisAdd BLAST92
Compositional biasi742 – 761Polar residuesSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminal part seems to be a myosin/calmodulin-binding domain, and the C-terminal a tropomyosin/actin/calmodulin-binding domain. These two domains are separated by a central helical region in the muscle forms.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the caldesmon family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QSYB, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P12957

Database of Orthologous Groups

More...
OrthoDBi
273358at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P12957

Family and domain databases

Database of protein disorder

More...
DisProti
DP00120

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006017, Caldesmon
IPR006018, Caldesmon_LSP

The PANTHER Classification System

More...
PANTHERi
PTHR18949, PTHR18949, 2 hits
PTHR18949:SF0, PTHR18949:SF0, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02029, Caldesmon, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01076, CALDESMON

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform Gizzard h-cad (identifier: P12957-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDDFERRREL RRQKREEMRL EAERLSYQRN DDDEEEAARE RRRRARQERL
60 70 80 90 100
RQKEEGDVSG EVTEKSEVNA QNSVAEEETK RSTDDEAALL ERLARREERR
110 120 130 140 150
QKRLQEALER QKEFDPTITD GSLSVPSRRE VNNVEENEIT GKEEKVETRQ
160 170 180 190 200
GRCEIEETET VTKSYQRNNW RQDGEEEGKK EEKDSEEEKP KEVPTEENQV
210 220 230 240 250
DVAVEKSTDK EEVVETKTLA VNAENDTNAM LEGEQSITDA ADKEKEEAEK
260 270 280 290 300
EREKLEAEEK ERLKAEEEKK AAEEKQKAEE EKKAAEERER AKAEEEKRAA
310 320 330 340 350
EERERAKAEE ERKAAEERER AKAEEERKAA EERAKAEEER KAAEERAKAE
360 370 380 390 400
EERKAAEERA KAEKERKAAE ERERAKAEEE KRAAEEKARL EAEKLKEKKK
410 420 430 440 450
MEEKKAQEEK AQANLLRKQE EDKEAKVEAK KESLPEKLQP TSKKDQVKDN
460 470 480 490 500
KDKEKAPKEE MKSVWDRKRG VPEQKAQNGE RELTTPKLKS TENAFGRSNL
510 520 530 540 550
KGAANAEAGS EKLKEKQQEA AVELDELKKR REERRKILEE EEQKKKQEEA
560 570 580 590 600
ERKIREEEEK KRMKEEIERR RAEAAEKRQK VPEDGVSEEK KPFKCFSPKG
610 620 630 640 650
SSLKIEERAE FLNKSAQKSG MKPAHTTAVV SKIDSRLEQY TSAVVGNKAA
660 670 680 690 700
KPAKPAASDL PVPAEGVRNI KSMWEKGNVF SSPGGTGTPN KETAGLKVGV
710 720 730 740 750
SSRINEWLTK TPEGNKSPAP KPSDLRPGDV SGKRNLWEKQ SVEKPAASSS
760 770
KVTATGKKSE TNGLRQFEKE P
Length:771
Mass (Da):88,747
Last modified:November 1, 1997 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i518912418DCFC14C
GO
Isoform Brain l-cad (identifier: P12957-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-24: MDDFERRRELRRQKREEMRLEAER → MISRSYCRQNLSSLSK
     200-446: Missing.

Show »
Length:516
Mass (Da):58,804
Checksum:i712F32945E59AEF6
GO
Isoform Gizzard l-cad (identifier: P12957-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     200-446: Missing.

Show »
Length:524
Mass (Da):60,167
Checksum:i956FAE770809A9B5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti318 – 332Missing AA sequence (PubMed:2760048).CuratedAdd BLAST15
Sequence conflicti452D → V in AAA48936 (PubMed:1824698).Curated1
Sequence conflicti762N → NA (PubMed:1824698).Curated1
Sequence conflicti762N → NA (PubMed:8250919).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0041521 – 24MDDFE…LEAER → MISRSYCRQNLSSLSK in isoform Brain l-cad. CuratedAdd BLAST24
Alternative sequenceiVSP_004153200 – 446Missing in isoform Brain l-cad and isoform Gizzard l-cad. 1 PublicationAdd BLAST247

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J04968 mRNA Translation: AAA49067.1
D17648 Genomic DNA Translation: BAA04539.1
M28417 mRNA Translation: AAA48810.1
M60620 mRNA Translation: AAA48936.1
D17648 Genomic DNA Translation: BAA04538.1
D17648 Genomic DNA Translation: BAA04540.1
M59762 mRNA Translation: AAA48649.1
D17552 Genomic DNA Translation: BAA04490.1
M26684 mRNA Translation: AAA48811.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A33430
A39038

NCBI Reference Sequences

More...
RefSeqi
NP_989489.1, NM_204158.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
373965

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
gga:373965

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J04968 mRNA Translation: AAA49067.1
D17648 Genomic DNA Translation: BAA04539.1
M28417 mRNA Translation: AAA48810.1
M60620 mRNA Translation: AAA48936.1
D17648 Genomic DNA Translation: BAA04538.1
D17648 Genomic DNA Translation: BAA04540.1
M59762 mRNA Translation: AAA48649.1
D17552 Genomic DNA Translation: BAA04490.1
M26684 mRNA Translation: AAA48811.1
PIRiA33430
A39038
RefSeqiNP_989489.1, NM_204158.1

3D structure databases

BMRBiP12957
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000021314

PTM databases

iPTMnetiP12957

Proteomic databases

PaxDbiP12957
PRIDEiP12957

Genome annotation databases

GeneIDi373965
KEGGigga:373965

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
800

Phylogenomic databases

eggNOGiENOG502QSYB, Eukaryota
InParanoidiP12957
OrthoDBi273358at2759
PhylomeDBiP12957

Enzyme and pathway databases

SABIO-RKiP12957

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P12957

Family and domain databases

DisProtiDP00120
InterProiView protein in InterPro
IPR006017, Caldesmon
IPR006018, Caldesmon_LSP
PANTHERiPTHR18949, PTHR18949, 2 hits
PTHR18949:SF0, PTHR18949:SF0, 2 hits
PfamiView protein in Pfam
PF02029, Caldesmon, 2 hits
PRINTSiPR01076, CALDESMON

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCALD1_CHICK
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P12957
Secondary accession number(s): Q03698
, Q90756, Q90761, Q92018, Q99230
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: November 1, 1997
Last modified: June 2, 2021
This is version 133 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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