UniProtKB - P12857 (ADT2_MAIZE)
Protein
ADP,ATP carrier protein 2, mitochondrial
Gene
ANT2
Organism
Zea mays (Maize)
Status
Functioni
Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 160 | ADPBy similarity | 1 | |
Binding sitei | 172 | ADPBy similarity | 1 | |
Binding sitei | 317 | ADPBy similarity | 1 |
GO - Molecular functioni
- ATP:ADP antiporter activity Source: GO_Central
GO - Biological processi
- mitochondrial ADP transmembrane transport Source: InterPro
- mitochondrial ATP transmembrane transport Source: InterPro
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: ADP,ATP carrier protein 2, mitochondrialAlternative name(s): ADP/ATP translocase 2 Adenine nucleotide translocator 2 Short name: ANT 2 |
Gene namesi | Name:ANT2 Synonyms:ANT-G2 |
Organismi | Zea mays (Maize) |
Taxonomic identifieri | 4577 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogonodae › Andropogoneae › Tripsacinae › Zea |
Proteomesi |
|
Organism-specific databases
MaizeGDBi | 17145 |
Subcellular locationi
Mitochondrion
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 87 – 114 | Helical; Name=1By similarityAdd BLAST | 28 | |
Transmembranei | 155 – 179 | Helical; Name=2By similarityAdd BLAST | 25 | |
Transmembranei | 188 – 208 | Helical; Name=3By similarityAdd BLAST | 21 | |
Transmembranei | 258 – 279 | Helical; Name=4By similarityAdd BLAST | 22 | |
Transmembranei | 293 – 313 | Helical; Name=5By similarityAdd BLAST | 21 | |
Transmembranei | 353 – 373 | Helical; Name=6By similarityAdd BLAST | 21 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 77 | MitochondrionSequence analysisAdd BLAST | 77 | |
ChainiPRO_0000019249 | 78 – 387 | ADP,ATP carrier protein 2, mitochondrialAdd BLAST | 310 |
Proteomic databases
PaxDbi | P12857 |
PRIDEi | P12857 |
Expressioni
Gene expression databases
ExpressionAtlasi | P12857, baseline and differential |
Genevisiblei | P12857, ZM |
Interactioni
Subunit structurei
Homodimer.
Protein-protein interaction databases
STRINGi | 4577.GRMZM2G135186_P03 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 85 – 178 | Solcar 1Add BLAST | 94 | |
Repeati | 190 – 282 | Solcar 2Add BLAST | 93 | |
Repeati | 290 – 376 | Solcar 3Add BLAST | 87 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 317 – 322 | Important for transport activityBy similarity | 6 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 317 – 322 | Nucleotide carrier signature motifBy similarity | 6 |
Domaini
The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. At least 2 of the odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.By similarity
Sequence similaritiesi
Keywords - Domaini
Repeat, Transit peptide, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0749, Eukaryota |
HOGENOMi | CLU_015166_12_1_1 |
OMAi | CWATIYK |
OrthoDBi | 870903at2759 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002113, ADT_euk_type IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
PANTHERi | PTHR45635, PTHR45635, 1 hit |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00927, ADPTRNSLCASE PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
P12857-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADQANQPTV LHKLGGQFHL SSSFSEGVRA RNICPSFSPY ERRFATRNYM
60 70 80 90 100
TQSLWGPSMS VSGGINVPVM PTPLFANAPA EKGGKNFMID FMMGGVSAAV
110 120 130 140 150
SKTAAAPIER VKLLIQNQDE MIKSGRLSEP YKGIADCFKR TIKDEGFSSL
160 170 180 190 200
WRGNTANVIR YFPTQALNFA FKDYFKRLFN FKKDRDGYWK WFAGNLASGG
210 220 230 240 250
AAGASSLFFV YSLDYARTRL ANDAKAAKGG GDRQFNGLVD VYRKTLKSDG
260 270 280 290 300
IAGLYRGFNI SCVGIIVYRG LYFGLYDSIK PVVLTGSLQD NFFASFALGW
310 320 330 340 350
LITNGAGLAS YPIDTVRRRM MMTSGEAVKY KSSLDAFQQI LKKEGPKSLF
360 370 380
KGAGANILRA IAGAGVLSGY DQLQILFFGK KYGSGGA
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1D6Q9C5 | A0A1D6Q9C5_MAIZE | ADP,ATP carrier protein 2, mitochon... | 542389 ZEAMMB73_Zm00001d051685 | 166 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 242 | Y → I in CAA33743 (PubMed:2547608).Curated | 1 | |
Sequence conflicti | 327 | A → G in CAA33743 (PubMed:2547608).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X59086 mRNA Translation: CAA41812.1 X15712 Genomic DNA Translation: CAA33743.1 |
PIRi | S16568 |
RefSeqi | NP_001105434.1, NM_001111964.1 XP_008677791.1, XM_008679569.1 |
Genome annotation databases
EnsemblPlantsi | Zm00001d051685_T001; Zm00001d051685_P001; Zm00001d051685 Zm00001d051685_T002; Zm00001d051685_P002; Zm00001d051685 |
GeneIDi | 542389 |
Gramenei | Zm00001d051685_T001; Zm00001d051685_P001; Zm00001d051685 Zm00001d051685_T002; Zm00001d051685_P002; Zm00001d051685 |
KEGGi | zma:542389 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X59086 mRNA Translation: CAA41812.1 X15712 Genomic DNA Translation: CAA33743.1 |
PIRi | S16568 |
RefSeqi | NP_001105434.1, NM_001111964.1 XP_008677791.1, XM_008679569.1 |
3D structure databases
SMRi | P12857 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4577.GRMZM2G135186_P03 |
Proteomic databases
PaxDbi | P12857 |
PRIDEi | P12857 |
Genome annotation databases
EnsemblPlantsi | Zm00001d051685_T001; Zm00001d051685_P001; Zm00001d051685 Zm00001d051685_T002; Zm00001d051685_P002; Zm00001d051685 |
GeneIDi | 542389 |
Gramenei | Zm00001d051685_T001; Zm00001d051685_P001; Zm00001d051685 Zm00001d051685_T002; Zm00001d051685_P002; Zm00001d051685 |
KEGGi | zma:542389 |
Organism-specific databases
MaizeGDBi | 17145 |
Phylogenomic databases
eggNOGi | KOG0749, Eukaryota |
HOGENOMi | CLU_015166_12_1_1 |
OMAi | CWATIYK |
OrthoDBi | 870903at2759 |
Gene expression databases
ExpressionAtlasi | P12857, baseline and differential |
Genevisiblei | P12857, ZM |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002113, ADT_euk_type IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
PANTHERi | PTHR45635, PTHR45635, 1 hit |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00927, ADPTRNSLCASE PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ADT2_MAIZE | |
Accessioni | P12857Primary (citable) accession number: P12857 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1989 |
Last sequence update: | August 1, 1992 | |
Last modified: | December 2, 2020 | |
This is version 138 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families