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Protein

50S ribosomal protein L7Ae

Gene

rpl7ae

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.Curated

Caution

Was originally thought to be a protein from the small subunit of the ribosome.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L7AeUniRule annotation
Alternative name(s):
Hs6
Ribosomal protein L8eUniRule annotation
Gene namesi
Name:rpl7aeUniRule annotation
Ordered Locus Names:rrnAC0103
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHaloarculaceaeHaloarcula
Proteomesi
  • UP000001169 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001367902 – 12050S ribosomal protein L7AeAdd BLAST119

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Interacts with protein L15e. Probably part of the RNase P complex.2 Publications

Protein-protein interaction databases

STRINGi272569.rrnAC0103

Structurei

Secondary structure

1120
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP12743
SMRiP12743
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP12743

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eL8 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01751 Archaea
COG1358 LUCA
HOGENOMiHOG000055225
KOiK02936
OMAiKPFYVRF
OrthoDBiPOG093Z0LB6

Family and domain databases

Gene3Di3.30.1330.30, 1 hit
HAMAPiMF_00326 Ribosomal_L7Ae_Arch, 1 hit
InterProiView protein in InterPro
IPR029064 L30e-like
IPR004038 Ribosomal_L7Ae/L30e/S12e/Gad45
IPR018492 Ribosomal_L7Ae/L8/Nhp2
IPR022481 Ribosomal_L7Ae_arc
IPR004037 Ribosomal_L7Ae_CS
IPR000948 Ribosomal_L7Ae_prok
PfamiView protein in Pfam
PF01248 Ribosomal_L7Ae, 1 hit
PRINTSiPR00881 L7ARS6FAMILY
PR00884 RIBOSOMALHS6
SUPFAMiSSF55315 SSF55315, 1 hit
TIGRFAMsiTIGR03677 eL8_ribo, 1 hit
PROSITEiView protein in PROSITE
PS01082 RIBOSOMAL_L7AE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P12743-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPVYVDFDVP ADLEDDALEA LEVARDTGAV KKGTNETTKS IERGSAELVF
60 70 80 90 100
VAEDVQPEEI VMHIPELADE KGVPFIFVEQ QDDLGHAAGL EVGSAAAAVT
110 120
DAGEADADVE DIADKVEELR
Length:120
Mass (Da):12,782
Last modified:January 23, 2007 - v4
Checksum:i96132F5CB51840A0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti104 – 111EADADVED → AAATV AA sequence (PubMed:3315748).Curated8

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA Translation: AAV45179.1
PIRiS00182 R5HSS6
RefSeqiWP_004593501.1, NC_006396.1

Genome annotation databases

EnsemblBacteriaiAAV45179; AAV45179; rrnAC0103
GeneIDi3130242
KEGGihma:rrnAC0103
PATRICifig|272569.17.peg.907

Similar proteinsi

Entry informationi

Entry nameiRL7A_HALMA
AccessioniPrimary (citable) accession number: P12743
Secondary accession number(s): Q5V5M3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: January 23, 2007
Last modified: October 25, 2017
This is version 140 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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