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Entry version 169 (12 Aug 2020)
Sequence version 3 (19 Jul 2005)
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Protein

Protein suppressor of white apricot

Gene

su(w[a])

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulator of pre-mRNA splicing (and, possibly, of other RNA processing events). Regulates its own expression at the level of RNA processing.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processmRNA processing, mRNA splicing, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein suppressor of white apricot
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:su(w[a])
Synonyms:su(wa)
ORF Names:CG3019
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0003638, su(w[a])

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000723241 – 963Protein suppressor of white apricotAdd BLAST963

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei438Phosphoserine1 Publication1
Modified residuei447Phosphoserine1 Publication1
Modified residuei448Phosphoserine1 Publication1
Modified residuei450Phosphoserine1 Publication1
Modified residuei649Phosphoserine1 Publication1
Modified residuei912Phosphoserine1 Publication1
Modified residuei914Phosphoserine1 Publication1
Modified residuei916Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P12297

PRoteomics IDEntifications database

More...
PRIDEi
P12297

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P12297

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Three mRNAs are produced during development. The smallest of these (3.5 kb RNA) is the majority species during precellular blastoderm development after which its levels drop rapidly, but persists as a minority species throughout the rest of the life of the organism. The larger two transcripts (4.4 and 5.2 kb RNAs) first appear around cellular blastoderm and levels increase substantially during next few hours and are the preponderant RNA species throughout the remainder of the life of the organism.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0003638, Expressed in male reproductive gland and 23 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P12297, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
57618, 11 interactors

Protein interaction database and analysis system

More...
IntActi
P12297, 8 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0070171

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P12297

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati234 – 276SURP motif 1Add BLAST43
Repeati483 – 523SURP motif 2Add BLAST41

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi449 – 454Poly-Glu6
Compositional biasi561 – 564Poly-Ala4
Compositional biasi747 – 750Poly-Asp4
Compositional biasi750 – 885Arg/Ser-rich (RS domain)Add BLAST136
Compositional biasi956 – 959Poly-Arg4

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

RS domain directs localization of proteins to the speckled subnuclear compartment and the purpose of this localization is to allow colocalization and co-concentration of components of the splicing and splicing regulatory machinery to permit relatively high rates and/or efficiencies of reaction and interaction.

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1847, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153892

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012240_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P12297

Identification of Orthologs from Complete Genome Data

More...
OMAi
LRAEPCQ

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P12297

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.790, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000061, Surp
IPR040397, SWAP
IPR035967, SWAP/Surp_sf
IPR019147, SWAP_N_domain

The PANTHER Classification System

More...
PANTHERi
PTHR13161, PTHR13161, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09750, DRY_EERY, 1 hit
PF01805, Surp, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01141, DRY_EERY, 1 hit
SM00648, SWAP, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109905, SSF109905, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50128, SURP, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform A (identifier: P12297-2) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLPYNVRNAG GGSVGGILRR TGQGSGTGST ILGNGNSPGA LGAGKVSSSL
60 70 80 90 100
ENHRQPPLEL LVFGYACKIF RDDEKAREMD HGKQLIPWMG DVNLKIDRYD
110 120 130 140 150
VRGALCELAP HEAPPGGYGN RLEYLSAEEQ RAEQLCEEER YLFLYNNEEE
160 170 180 190 200
LRLRQEEDLK RLQQETSGGC FSQVGFQYDG QSAASTSIGG SSTATSQLSP
210 220 230 240 250
NSEESELPFV LPYTLMMAPP LDMQLPETMK QHAIIEKTAR FIATQGAQME
260 270 280 290 300
ILIKAKQANN TQFDFLTQGG HLQPYYRHLL AAIKAAKFPP APQTPLDQQN
310 320 330 340 350
TDKEAPSADD HSEEVAGGRR NPNQVVITVP TIKYKPSANC AYTQLISKIK
360 370 380 390 400
GVPLQAVLQE DESSNPGNSQ HSGGTASPAL SCRSEGHNSQ GGEFTPVLLQ
410 420 430 440 450
YNGSTFTHEE ESSNREQQDD NDVNGGEPPQ VELLKNTSAL ALAQNYSSES
460 470 480 490 500
EEEEDQVQPE KEEEKKPEPV LTFPVPKDSL RHIIDKTATY VIKNGRQFEE
510 520 530 540 550
TLRTKSVDRF SFLLPANEYY PYYLYKVTGD VDAASKEEKT RKAAAVAAAL
560 570 580 590 600
MSKKGLSFGG AAAAVSGSNL DKAPVSFSIR ARDDQCPLQH TLPQEASDEE
610 620 630 640 650
TSSNAAGVEH VRPGMPDSVQ RAIKQVETQL LARTAGQKGN ITASPSCSSP
660 670 680 690 700
QKEQRQAEER VKDKLAQIAR EKLNGMISRE KQLQLERKRK ALAFLNQIKG
710 720 730 740 750
EGAIVGSAVP VVGPNPPESA AGAATADSGD ESGDSVRSIP ITYFGPDDDD
760 770 780 790 800
EVGEQRPEMR LIGSTQKDEE DDDEEDGGDL EKYNLLNDDS TNTFTSKPVL
810 820 830 840 850
PPTAAPPPAA VLLSDDDDVQ LVATTSTRSS SSRHLKTHRR SRSRSKNVRS
860 870 880 890 900
SDSSPSSRES SRRRRQKSSR LSREPSSNPP RKSQHSSTQR KKTPKKRRRS
910 920 930 940 950
KSRSRSKSIR RSRSISILRN NRRSRSRSPS CRNAEQRRQQ DRRRTPTKKS
960
HKRHKRRRRS SSP
Length:963
Mass (Da):106,141
Last modified:July 19, 2005 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9682B6516D9F085F
GO
Isoform B (identifier: P12297-3) [UniParc]FASTAAdd to basket
Also known as: C

The sequence of this isoform differs from the canonical sequence as follows:
     1-215: Missing.

Show »
Length:748
Mass (Da):82,693
Checksum:i4EAE7EDEC778C037
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9MS02M9MS02_DROME
Suppressor of white-apricot, isofor...
su(w[a]) Dmel\CG3019, DmSWAP, EG:BACR7A4.10, su(w), Su(w[a])
748Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A4V3U2A4V3U2_DROME
Suppressor of white-apricot, isofor...
su(w[a]) Dmel\CG3019, DmSWAP, EG:BACR7A4.10, su(w), Su(w[a])
176Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9NDH9M9NDH9_DROME
Suppressor of white-apricot, isofor...
su(w[a]) Dmel\CG3019, DmSWAP, EG:BACR7A4.10, su(w), Su(w[a])
217Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9NFQ2M9NFQ2_DROME
Suppressor of white-apricot, isofor...
su(w[a]) Dmel\CG3019, DmSWAP, EG:BACR7A4.10, su(w), Su(w[a])
186Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PDF8M9PDF8_DROME
Suppressor of white-apricot, isofor...
su(w[a]) Dmel\CG3019, DmSWAP, EG:BACR7A4.10, su(w), Su(w[a])
160Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAS65241 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAA29812 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAA29813 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB65879 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB65880 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti49S → SS in CAA29812 (PubMed:12537569).Curated1
Sequence conflicti49S → SS in CAA29813 (PubMed:12537569).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0044361 – 215Missing in isoform B. CuratedAdd BLAST215

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X06589 Genomic DNA Translation: CAA29812.1 Sequence problems.
X06589 Genomic DNA Translation: CAA29813.1 Sequence problems.
AE014298 Genomic DNA Translation: AAG22382.2
AE014298 Genomic DNA Translation: AAS65241.1 Sequence problems.
AL109630, AL132651 Genomic DNA Translation: CAB65879.1 Sequence problems.
AL132651, AL109630 Genomic DNA Translation: CAB65880.1 Sequence problems.
AY118635 mRNA Translation: AAM50004.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S06028

NCBI Reference Sequences

More...
RefSeqi
NP_476756.2, NM_057408.6 [P12297-2]
NP_996323.1, NM_206600.3
NP_996324.1, NM_206601.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0070176; FBpp0070171; FBgn0003638 [P12297-2]
FBtr0302884; FBpp0292012; FBgn0003638 [P12297-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
31054

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG3019

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X06589 Genomic DNA Translation: CAA29812.1 Sequence problems.
X06589 Genomic DNA Translation: CAA29813.1 Sequence problems.
AE014298 Genomic DNA Translation: AAG22382.2
AE014298 Genomic DNA Translation: AAS65241.1 Sequence problems.
AL109630, AL132651 Genomic DNA Translation: CAB65879.1 Sequence problems.
AL132651, AL109630 Genomic DNA Translation: CAB65880.1 Sequence problems.
AY118635 mRNA Translation: AAM50004.1
PIRiS06028
RefSeqiNP_476756.2, NM_057408.6 [P12297-2]
NP_996323.1, NM_206600.3
NP_996324.1, NM_206601.3

3D structure databases

SMRiP12297
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi57618, 11 interactors
IntActiP12297, 8 interactors
STRINGi7227.FBpp0070171

PTM databases

iPTMnetiP12297

Proteomic databases

PaxDbiP12297
PRIDEiP12297

Genome annotation databases

EnsemblMetazoaiFBtr0070176; FBpp0070171; FBgn0003638 [P12297-2]
FBtr0302884; FBpp0292012; FBgn0003638 [P12297-3]
GeneIDi31054
KEGGidme:Dmel_CG3019

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
31054
FlyBaseiFBgn0003638, su(w[a])

Phylogenomic databases

eggNOGiKOG1847, Eukaryota
GeneTreeiENSGT00940000153892
HOGENOMiCLU_012240_0_0_1
InParanoidiP12297
OMAiLRAEPCQ
PhylomeDBiP12297

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
31054, 1 hit in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
su(w[a]), fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
31054

Protein Ontology

More...
PROi
PR:P12297

Gene expression databases

BgeeiFBgn0003638, Expressed in male reproductive gland and 23 other tissues
ExpressionAtlasiP12297, baseline and differential

Family and domain databases

Gene3Di1.10.10.790, 2 hits
InterProiView protein in InterPro
IPR000061, Surp
IPR040397, SWAP
IPR035967, SWAP/Surp_sf
IPR019147, SWAP_N_domain
PANTHERiPTHR13161, PTHR13161, 1 hit
PfamiView protein in Pfam
PF09750, DRY_EERY, 1 hit
PF01805, Surp, 2 hits
SMARTiView protein in SMART
SM01141, DRY_EERY, 1 hit
SM00648, SWAP, 2 hits
SUPFAMiSSF109905, SSF109905, 2 hits
PROSITEiView protein in PROSITE
PS50128, SURP, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSUWA_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P12297
Secondary accession number(s): Q24543
, Q7KW21, Q8MSS2, Q9I7D2, Q9TVZ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: July 19, 2005
Last modified: August 12, 2020
This is version 169 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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