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Entry version 193 (23 Feb 2022)
Sequence version 1 (01 Oct 1989)
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Protein

Regulatory protein SIR4

Gene

SIR4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR (PubMed:18039933).

The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure (PubMed:18039933).

Involves the compaction of chromatin fiber into a more condensed form (PubMed:18039933).

2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Regulatory protein SIR4
Alternative name(s):
Silent information regulator 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SIR4
Synonyms:ASD1, STE9, UTH2
Ordered Locus Names:YDR227W
ORF Names:YD9934.12
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000002635, SIR4

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YDR227W

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000977691 – 1358Regulatory protein SIR4Add BLAST1358

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei692PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki1128Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)1 Publication

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P11978

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P11978

PRoteomics IDEntifications database

More...
PRIDEi
P11978

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P11978

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer (PubMed:12791253).

Interacts with MPS3 (PubMed:18039933).

Interacts with RIS1 (PubMed:9271422).

Interacts with SIR1, SIR2 and SIR3 (PubMed:11722841).

Interacts with YKU80 (PubMed:14551211).

Interacts with UBP10 (PubMed:10490600, PubMed:26149687).

1 Publication5 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
32279, 132 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1811, Sir2-3-4 silent chromatin complex

Database of interacting proteins

More...
DIPi
DIP-33N

Protein interaction database and analysis system

More...
IntActi
P11978, 36 interactors

Molecular INTeraction database

More...
MINTi
P11978

STRING: functional protein association networks

More...
STRINGi
4932.YDR227W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P11978, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11358
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P11978

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P11978

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 98DisorderedSequence analysisAdd BLAST98
Regioni252 – 277DisorderedSequence analysisAdd BLAST26
Regioni356 – 466DisorderedSequence analysisAdd BLAST111
Regioni498 – 544DisorderedSequence analysisAdd BLAST47
Regioni677 – 726DisorderedSequence analysisAdd BLAST50
Regioni752 – 787DisorderedSequence analysisAdd BLAST36
Regioni913 – 970DisorderedSequence analysisAdd BLAST58

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1271 – 1347Add BLAST77

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 19Polar residuesSequence analysisAdd BLAST19
Compositional biasi22 – 38Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi50 – 98Polar residuesSequence analysisAdd BLAST49
Compositional biasi370 – 389Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi397 – 420Basic and acidic residuesSequence analysisAdd BLAST24
Compositional biasi427 – 442Polar residuesSequence analysisAdd BLAST16
Compositional biasi501 – 519Polar residuesSequence analysisAdd BLAST19
Compositional biasi688 – 717Polar residuesSequence analysisAdd BLAST30
Compositional biasi753 – 783Polar residuesSequence analysisAdd BLAST31
Compositional biasi913 – 953Polar residuesSequence analysisAdd BLAST41

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S6NU, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_257187_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P11978

Identification of Orthologs from Complete Genome Data

More...
OMAi
ETERNAM

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13746, Sir4p-SID_like, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031556, SIR4_SID

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16991, SIR4_SID, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P11978-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPNDNKTPNR SSTPKFTKKP VTPNDKIPER EEKSNEVKTP KIPLFTFAKS
60 70 80 90 100
KNYSRPSTAI HTSPHQPSDV KPTSHKQLQQ PKSSPLKKNN YNSFPHSNLE
110 120 130 140 150
KISNSKLLSL LRSKTSAGRI ESNNPSHDAS RSLASFEQTA FSRHAQQQTS
160 170 180 190 200
TFNSKPVRTI VPISTSQTNN SFLSGVKSLL SEEKIRDYSK EILGINLANE
210 220 230 240 250
QPVLEKPLKK GSADIGASVI SLTKDKSIRK DTVEEKKEEK LNIGKNFAHS
260 270 280 290 300
DSLSVPKVSA GDSGISPEES KARSPGIAKP NAIQTEVYGI NEESTNERLE
310 320 330 340 350
INQEKPVKLD ENSANSTVAS ALDTNGTSAT TETLTSKKIV PSPKKVAIDQ
360 370 380 390 400
DKITLHDEKT LAPSKHQPIT SEQKMKEDAD LKRMEILKSP HLSKSPADRP
410 420 430 440 450
QGRRNSRNFS TRDEETTKLA FLVEYEGQEN NYNSTSRSTE KKNDMNTSAK
460 470 480 490 500
NKNGENKKIG KRPPEIMSTE AHVNKVTEET TKQIQSVRID GRKVLQKVQG
510 520 530 540 550
ESHIDSRNNT LNVTPSKRPQ LGEIPNPMKK HKPNEGRTPN ISNGTINIQK
560 570 580 590 600
KLEPKEIVRD ILHTKESSNE AKKTIQNPLN KSQNTALPST HKVTQKKDIK
610 620 630 640 650
IGTNDLFQVE SAPKISSEID RENVKSKDEP VSKAVESKSL LNLFSNVLKA
660 670 680 690 700
PFIKSESKPF SSDALSKEKA NFLETIASTE KPENKTDKVS LSQPVSASKH
710 720 730 740 750
EYSDNFPVSL SQPSKKSFAN HTEDEQIEKK KICRGRMNTI ITHPGKMELV
760 770 780 790 800
YVSDSDDSSS DNDSLTDLES LSSGESNEIK VTNDLDTSAE KDQIQAGKWF
810 820 830 840 850
DPVLDWRKSD RELTKNILWR IADKTTYDKE TITDLIEQGI PKHSYLSGNP
860 870 880 890 900
LTSVTNDICS VENYETSSAF FYQQVHKKDR LQYLPLYAVS TFENTNNTEK
910 920 930 940 950
NDVTNKNINI GKHSQEQNSS SAKPSQIPTV SSPLGFEETK LSTTPTKSNR
960 970 980 990 1000
RVSHSDTNSS KPKNTKENLS KSSWRQEWLA NLKLISVSLV DEFPSELSDS
1010 1020 1030 1040 1050
DRQIINEKMQ LLKDIFANNL KSAISNNFRE SDIIILKGEI EDYPMSSEIK
1060 1070 1080 1090 1100
IYYNELQNKP DAKKARFWSF MKTQRFVSNM GFDIQKSCEP VSISTSVKPH
1110 1120 1130 1140 1150
VVEPEHMADA KIMPKDILQI TKKPLMVKNV KPSSPPDVKS LVQLSTMETK
1160 1170 1180 1190 1200
TLPEKKQFDS IFNSNKAKII PGNGKHASEN ISLSFSRPAS YGYFSVGKRV
1210 1220 1230 1240 1250
PIVEDRRVKQ LDDITDSNTT EILTSVDVLG THSQTGTQQS NMYTSTQKTE
1260 1270 1280 1290 1300
LEIDNKDSVT ECSKDMKEDG LSFVDIVLSK AASALDEKEK QLAVANEIIR
1310 1320 1330 1340 1350
SLSDEVMRNE IRITSLQGDL TFTKKCLENA RSQISEKDAK INKLMEKDFQ

VNKEIKPY
Length:1,358
Mass (Da):152,062
Last modified:October 1, 1989 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9C698765964F094E
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti994P → L. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M37249 Genomic DNA Translation: AAA20881.1
U13239 Genomic DNA Translation: AAC33144.1
Z48612 Genomic DNA Translation: CAA88507.1
BK006938 Genomic DNA Translation: DAA12069.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A29360

NCBI Reference Sequences

More...
RefSeqi
NP_010513.1, NM_001180535.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YDR227W_mRNA; YDR227W; YDR227W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
851813

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YDR227W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37249 Genomic DNA Translation: AAA20881.1
U13239 Genomic DNA Translation: AAC33144.1
Z48612 Genomic DNA Translation: CAA88507.1
BK006938 Genomic DNA Translation: DAA12069.1
PIRiA29360
RefSeqiNP_010513.1, NM_001180535.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NYHX-ray3.10A1198-1358[»]
1PL5X-ray2.50A/S1217-1358[»]
4IAOX-ray2.90C/D737-893[»]
6QSZX-ray2.50A/C/E/G/I/K/M/O961-1085[»]
6QTMX-ray3.00A/B/C961-1085[»]
6RR0X-ray2.18A/B/C/D/E/F/G961-1085[»]
6RRVX-ray1.10A961-1085[»]
SMRiP11978
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi32279, 132 interactors
ComplexPortaliCPX-1811, Sir2-3-4 silent chromatin complex
DIPiDIP-33N
IntActiP11978, 36 interactors
MINTiP11978
STRINGi4932.YDR227W

PTM databases

iPTMnetiP11978

Proteomic databases

MaxQBiP11978
PaxDbiP11978
PRIDEiP11978

Genome annotation databases

EnsemblFungiiYDR227W_mRNA; YDR227W; YDR227W
GeneIDi851813
KEGGisce:YDR227W

Organism-specific databases

SGDiS000002635, SIR4
VEuPathDBiFungiDB:YDR227W

Phylogenomic databases

eggNOGiENOG502S6NU, Eukaryota
HOGENOMiCLU_257187_0_0_1
InParanoidiP11978
OMAiETERNAM

Miscellaneous databases

EvolutionaryTraceiP11978

Protein Ontology

More...
PROi
PR:P11978
RNActiP11978, protein

Family and domain databases

CDDicd13746, Sir4p-SID_like, 1 hit
InterProiView protein in InterPro
IPR031556, SIR4_SID
PfamiView protein in Pfam
PF16991, SIR4_SID, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSIR4_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P11978
Secondary accession number(s): D6VSK9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: February 23, 2022
This is version 193 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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