We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - P11904 (PARM_ECOLX)
Protein
Plasmid segregation protein ParM
Gene
parM
Organism
Escherichia coli
Status
Functioni
Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.
GO - Molecular functioni
- identical protein binding Source: IntAct
GO - Biological processi
- plasmid partitioning Source: UniProtKB-KW
Keywordsi
Biological process | Plasmid partition |
Names & Taxonomyi
Protein namesi | Recommended name: Plasmid segregation protein ParMAlternative name(s): ParA locus 36 kDa protein Protein StbA |
Gene namesi | Name:parM Synonyms:stbA |
Encoded oni | Plasmid IncFII R100 (NR1)1 Publication Plasmid IncFII R11 Publication |
Organismi | Escherichia coli |
Taxonomic identifieri | 562 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000068441 | 1 – 320 | Plasmid segregation protein ParMAdd BLAST | 320 |
Interactioni
Subunit structurei
Homopolymerizes into double helical protofilaments with a longitudinal repeat similar to filamentous actin.
Binary interactionsi
P11904
With | #Exp. | IntAct |
---|---|---|
itself | 5 | EBI-15658818,EBI-15658818 |
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
DIPi | DIP-29623N |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P11904 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P11904 |
Family & Domainsi
Sequence similaritiesi
Belongs to the plasmid partition ParM family.Curated
Family and domain databases
CDDi | cd10227, ParM_like, 1 hit |
InterProi | View protein in InterPro IPR043129, ATPase_NBD IPR042051, ParM-like IPR009440, Plasmid_segregation_ParM/StbA |
Pfami | View protein in Pfam PF06406, StbA, 1 hit |
SUPFAMi | SSF53067, SSF53067, 2 hits |
i Sequence
Sequence statusi: Complete.
P11904-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLVFIDDGST NIKLQWQESD GTIKQHISPN SFKREWAVSF GDKKVFNYTL
60 70 80 90 100
NGEQYSFDPI SPDAVVTTNI AWQYSDVNVV AVHHALLTSG LPVSEVDIVC
110 120 130 140 150
TLPLTEYYDR NNQPNTENIE RKKANFRKKI TLNGGDTFTI KDVKVMPESI
160 170 180 190 200
PAGYEVLQEL DELDSLLIID LGGTTLDISQ VMGKLSGISK IYGDSSLGVS
210 220 230 240 250
LVTSAVKDAL SLARTKGSSY LADDIIIHRK DNNYLKQRIN DENKISIVTE
260 270 280 290 300
AMNEALRKLE QRVLNTLNEF SGYTHVMVIG GGAELICDAV KKHTQIRDER
310 320
FFKTNNSQYD LVNGMYLIGN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X12777 Genomic DNA Translation: CAA31264.1 X04268 Genomic DNA Translation: CAA27818.1 |
PIRi | A24920 |
RefSeqi | NP_957570.1, NC_005327.1 WP_000959884.1, NZ_WVVU01000024.1 YP_001096425.1, NC_009133.1 YP_002456142.1, NC_011812.1 YP_003108258.1, NC_013121.1 YP_006953486.1, NC_019073.1 YP_006953911.1, NC_019090.1 YP_006954241.1, NC_019095.1 YP_006990723.1, NC_019424.1 YP_007447518.1, NC_020278.2 YP_008531404.1, NC_022333.1 YP_009068579.1, NC_025141.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X12777 Genomic DNA Translation: CAA31264.1 X04268 Genomic DNA Translation: CAA27818.1 |
PIRi | A24920 |
RefSeqi | NP_957570.1, NC_005327.1 WP_000959884.1, NZ_WVVU01000024.1 YP_001096425.1, NC_009133.1 YP_002456142.1, NC_011812.1 YP_003108258.1, NC_013121.1 YP_006953486.1, NC_019073.1 YP_006953911.1, NC_019090.1 YP_006954241.1, NC_019095.1 YP_006990723.1, NC_019424.1 YP_007447518.1, NC_020278.2 YP_008531404.1, NC_022333.1 YP_009068579.1, NC_025141.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1MWK | X-ray | 2.30 | A/B | 1-320 | [»] | |
1MWM | X-ray | 2.00 | A/B | 1-320 | [»] | |
2QU4 | electron microscopy | 16.00 | A | 1-320 | [»] | |
2ZGY | X-ray | 1.90 | A/B | 1-320 | [»] | |
2ZGZ | X-ray | 2.25 | A/B | 1-320 | [»] | |
2ZHC | electron microscopy | 23.80 | A | 1-320 | [»] | |
3IKU | electron microscopy | - | A/B/C/D/E/F/G/H/I/J/K/L | 1-320 | [»] | |
3IKY | electron microscopy | - | A/B/C/D/E/F/G/H/I/J/K/L | 1-320 | [»] | |
4A61 | X-ray | 2.00 | A | 2-320 | [»] | |
4A62 | X-ray | 2.20 | A/B | 1-320 | [»] | |
4A6J | electron microscopy | 7.20 | A/B/C/D/E/F/G/H/I/J | 1-320 | [»] | |
5AEY | electron microscopy | 4.30 | A/B/C/D/E | 1-318 | [»] | |
5AI7 | electron microscopy | - | A/B/C/D/E/F/G/H/I/J/K/L/M/N | 1-318 | [»] | |
SMRi | P11904 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
DIPi | DIP-29623N |
Miscellaneous databases
EvolutionaryTracei | P11904 |
Family and domain databases
CDDi | cd10227, ParM_like, 1 hit |
InterProi | View protein in InterPro IPR043129, ATPase_NBD IPR042051, ParM-like IPR009440, Plasmid_segregation_ParM/StbA |
Pfami | View protein in Pfam PF06406, StbA, 1 hit |
SUPFAMi | SSF53067, SSF53067, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | PARM_ECOLX | |
Accessioni | P11904Primary (citable) accession number: P11904 Secondary accession number(s): P10028 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1989 |
Last sequence update: | October 1, 1989 | |
Last modified: | June 2, 2021 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, PlasmidDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families