UniProtKB - P11904 (PARM_ECOLX)

BLAST

>sp|P11904|PARM_ECOLX Plasmid segregation protein ParM OS=Escherichia coli OX=562 GN=parM PE=1 SV=1
MLVFIDDGSTNIKLQWQESDGTIKQHISPNSFKREWAVSFGDKKVFNYTLNGEQYSFDPI
SPDAVVTTNIAWQYSDVNVVAVHHALLTSGLPVSEVDIVCTLPLTEYYDRNNQPNTENIE
RKKANFRKKITLNGGDTFTIKDVKVMPESIPAGYEVLQELDELDSLLIIDLGGTTLDISQ
VMGKLSGISKIYGDSSLGVSLVTSAVKDALSLARTKGSSYLADDIIIHRKDNNYLKQRIN
DENKISIVTEAMNEALRKLEQRVLNTLNEFSGYTHVMVIGGGAELICDAVKKHTQIRDER
FFKTNNSQYDLVNGMYLIGN

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History
Entry version 103 (07 Nov 2018)
Sequence version 1 (01 Oct 1989)
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Protein

Plasmid segregation protein ParM

Gene

parM

Organism

Escherichia coli

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.

GO - Molecular functionⁱ

identical protein binding
Source: IntAct
Inferred from physical interactionⁱ

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

plasmid partitioning Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Plasmid partition

Biological process

Plasmid partition

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Plasmid segregation protein ParM Alternative name(s): ParA locus 36 kDa protein Protein StbA
Gene namesⁱ	Name:parM Synonyms:stbA
Encoded onⁱ	Plasmid IncFII R100 (NR1)1 Publication Plasmid IncFII R11 Publication
Organismⁱ	Escherichia coli
Taxonomic identifierⁱ	562 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000068441	1 – 320	Plasmid segregation protein ParMAdd BLAST		320

Proteomic databases

PRIDEⁱ	P11904

PRIDEⁱ

P11904

Interactionⁱ

Subunit structureⁱ

Homopolymerizes into double helical protofilaments with a longitudinal repeat similar to filamentous actin.

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
itself		5	EBI-15658818,EBI-15658818

With

Entry

#Exp.

IntAct

Notes

itself

EBI-15658818,EBI-15658818

GO - Molecular functionⁱ

identical protein binding
Source: IntAct
Inferred from physical interactionⁱ

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-29623N

DIPⁱ

DIP-29623N

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	2 – 7	Combined sources	6
Beta strandⁱ	9 – 17	Combined sources	9
Beta strandⁱ	19 – 21	Combined sources	3
Beta strandⁱ	23 – 29	Combined sources	7
Beta strandⁱ	32 – 35	Combined sources	4
Beta strandⁱ	40 – 42	Combined sources	3
Beta strandⁱ	47 – 50	Combined sources	4
Beta strandⁱ	53 – 57	Combined sources	5
Helixⁱ	71 – 74	Combined sources	4
Helixⁱ	76 – 89	Combined sources	14
Beta strandⁱ	95 – 102	Combined sources	8
Helixⁱ	104 – 107	Combined sources	4
Beta strandⁱ	112 – 114	Combined sources	3
Helixⁱ	116 – 125	Combined sources	10
Beta strandⁱ	130 – 132	Combined sources	3
Beta strandⁱ	139 – 149	Combined sources	11
Helixⁱ	150 – 159	Combined sources	10
Beta strandⁱ	165 – 171	Combined sources	7
Beta strandⁱ	176 – 182	Combined sources	7
Helixⁱ	183 – 185	Combined sources	3
Beta strandⁱ	188 – 194	Combined sources	7
Helixⁱ	200 – 209	Combined sources	10
Helixⁱ	216 – 218	Combined sources	3
Helixⁱ	219 – 227	Combined sources	9
Turnⁱ	228 – 230	Combined sources	3
Helixⁱ	232 – 238	Combined sources	7
Beta strandⁱ	239 – 242	Combined sources	4
Helixⁱ	245 – 267	Combined sources	23
Beta strandⁱ	275 – 280	Combined sources	6
Helixⁱ	283 – 292	Combined sources	10
Helixⁱ	298 – 300	Combined sources	3
Helixⁱ	307 – 309	Combined sources	3
Helixⁱ	310 – 319	Combined sources	10

Show more details

3D structure databases

ProteinModelPortalⁱ	P11904
SMRⁱ	P11904
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	P11904

EvolutionaryTraceⁱ

P11904

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the plasmid partition ParM family.Curated

Family and domain databases

InterProⁱ	View protein in InterPro IPR009440 Plasmid_segregation_ParM/StbA
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF06406 StbA, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P11904-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLVFIDDGST NIKLQWQESD GTIKQHISPN SFKREWAVSF GDKKVFNYTL 
        60         70         80         90        100
NGEQYSFDPI SPDAVVTTNI AWQYSDVNVV AVHHALLTSG LPVSEVDIVC 
       110        120        130        140        150
TLPLTEYYDR NNQPNTENIE RKKANFRKKI TLNGGDTFTI KDVKVMPESI 
       160        170        180        190        200
PAGYEVLQEL DELDSLLIID LGGTTLDISQ VMGKLSGISK IYGDSSLGVS 
       210        220        230        240        250
LVTSAVKDAL SLARTKGSSY LADDIIIHRK DNNYLKQRIN DENKISIVTE 
       260        270        280        290        300
AMNEALRKLE QRVLNTLNEF SGYTHVMVIG GGAELICDAV KKHTQIRDER 
       310        320
FFKTNNSQYD LVNGMYLIGN

Length:320

Mass (Da):35,765

Last modified:October 1, 1989 - v1

Checksum:ⁱ52B3239C0A567312

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X12777 Genomic DNA Translation: CAA31264.1 X04268 Genomic DNA Translation: CAA27818.1
PIRⁱ	A24920
NCBI Reference Sequences More...RefSeqⁱ	NP_957570.1, NC_005327.1 WP_000959884.1, NZ_UIMW01000053.1 YP_001096425.1, NC_009133.1 YP_002456142.1, NC_011812.1 YP_003108258.1, NC_013121.1 YP_006953486.1, NC_019073.1 YP_006953911.1, NC_019090.1 YP_006954241.1, NC_019095.1 YP_006990723.1, NC_019424.1 YP_007447518.1, NC_020278.2 YP_008531404.1, NC_022333.1 YP_009068579.1, NC_025141.1

Genome annotation databases

GeneIDⁱ	13906411 13906847 13906930 13982300 14612532 16833925 20491711 2716545 4924750 7256899 8319203

GeneIDⁱ

13906411
13906847
13906930
13982300
14612532
16833925
20491711
2716545
4924750
7256899
8319203

Protein	Similar proteins		Species	Score	Length	Source
P11904	Plasmid segregation protein ParM		Klebsiella pneumoniae subsp. pneumoniae		320	UniRef100_P11904
Putative plasmid stabilazation protein		uncultured bacterium		320
Plasmid segregation protein		SHISO		320
Plasmid segregation protein		Escherichia coli O119:H6		320
Plasmid partition protein		SHIFL		320
+53

Protein	Similar proteins		Species	Score	Length	Source
P11904	Plasmid segregation protein ParM		Klebsiella pneumoniae subsp. pneumoniae		320	UniRef90_P11904
Putative plasmid stabilazation protein		uncultured bacterium		320
Plasmid segregation protein		SHISO		320
Plasmid segregation protein		Escherichia coli O119:H6		320
Plasmid partition protein		SHIFL		320
+229

Protein	Similar proteins		Species	Score	Length	Source
P11904	Plasmid segregation protein ParM		Klebsiella pneumoniae subsp. pneumoniae		320	UniRef50_P11904
Putative plasmid stabilazation protein		uncultured bacterium		320
Plasmid segregation protein		SHISO		320
Plasmid segregation protein		Escherichia coli O119:H6		320
Plasmid partition protein		SHIFL		320
+442

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X12777 Genomic DNA Translation: CAA31264.1 X04268 Genomic DNA Translation: CAA27818.1
PIRⁱ	A24920
RefSeqⁱ	NP_957570.1, NC_005327.1 WP_000959884.1, NZ_UIMW01000053.1 YP_001096425.1, NC_009133.1 YP_002456142.1, NC_011812.1 YP_003108258.1, NC_013121.1 YP_006953486.1, NC_019073.1 YP_006953911.1, NC_019090.1 YP_006954241.1, NC_019095.1 YP_006990723.1, NC_019424.1 YP_007447518.1, NC_020278.2 YP_008531404.1, NC_022333.1 YP_009068579.1, NC_025141.1

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1MWK	X-ray	2.30	A/B	1-320	[»]
	1MWM	X-ray	2.00	A/B	1-320	[»]
	2QU4	electron microscopy	16.00	A	1-320	[»]
	2ZGY	X-ray	1.90	A/B	1-320	[»]
	2ZGZ	X-ray	2.25	A/B	1-320	[»]
	2ZHC	electron microscopy	23.80	A	1-320	[»]
	3IKU	electron microscopy	-	A/B/C/D/E/F/G/H/I/J/K/L	1-320	[»]
	3IKY	electron microscopy	-	A/B/C/D/E/F/G/H/I/J/K/L	1-320	[»]
	4A61	X-ray	2.00	A	2-320	[»]
	4A62	X-ray	2.20	A/B	1-320	[»]
	4A6J	electron microscopy	7.20	A/B/C/D/E/F/G/H/I/J	1-320	[»]
	5AEY	electron microscopy	4.30	A/B/C/D/E	1-318	[»]
	5AI7	electron microscopy	-	A/B/C/D/E/F/G/H/I/J/K/L/M/N	1-318	[»]
ProteinModelPortalⁱ	P11904
SMRⁱ	P11904
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

DIPⁱ	DIP-29623N

Proteomic databases

PRIDEⁱ	P11904

PRIDEⁱ

P11904

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	13906411 13906847 13906930 13982300 14612532 16833925 20491711 2716545 4924750 7256899 8319203

GeneIDⁱ

13906411
13906847
13906930
13982300
14612532
16833925
20491711
2716545
4924750
7256899
8319203

Miscellaneous databases

EvolutionaryTraceⁱ	P11904

EvolutionaryTraceⁱ

P11904

Family and domain databases

InterProⁱ	View protein in InterPro IPR009440 Plasmid_segregation_ParM/StbA
Pfamⁱ	View protein in Pfam PF06406 StbA, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	PARM_ECOLX
Accessionⁱ	P11904Primary (citable) accession number: P11904 Secondary accession number(s): P10028
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
	Last sequence update:	October 1, 1989
	Last modified:	November 7, 2018
	This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P11904 (PARM_ECOLX)

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Plasmid segregation protein ParM

parM

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ