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Protein

Endothiapepsin

Gene

EAPA

Organism
Cryphonectria parasitica (Chestnut blight fungus) (Endothia parasitica)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Hydrolysis of proteins with specificity similar to that of pepsin A, prefers hydrophobic residues at P1 and P1', but does not cleave 14-Ala-|-Leu-15 in the B chain of insulin or Z-Glu-Tyr. Clots milk.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei1241
Active sitei2881

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl protease, Hydrolase, Protease

Enzyme and pathway databases

BRENDAi3.4.23.22 2077

Protein family/group databases

MEROPSiA01.017

Names & Taxonomyi

Protein namesi
Recommended name:
Endothiapepsin (EC:3.4.23.22)
Alternative name(s):
Aspartate protease
Gene namesi
Name:EAPA
Synonyms:EPN-1
OrganismiCryphonectria parasitica (Chestnut blight fungus) (Endothia parasitica)
Taxonomic identifieri5116 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeDiaporthalesCryphonectriaceaeCryphonectria-Endothia species complexCryphonectria

Pathology & Biotechi

Protein family/group databases

Allergomei3881 Cry p AP

Chemistry databases

ChEMBLiCHEMBL1075067

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
PropeptideiPRO_000002587921 – 89Activation peptide1 PublicationAdd BLAST69
ChainiPRO_000002588090 – 419EndothiapepsinAdd BLAST330

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi344 ↔ 379

Keywords - PTMi

Disulfide bond, Zymogen

Interactioni

Chemistry databases

BindingDBiP11838

Structurei

Secondary structure

1419
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi92 – 100Combined sources9
Beta strandi106 – 112Combined sources7
Turni113 – 116Combined sources4
Beta strandi117 – 124Combined sources8
Beta strandi130 – 132Combined sources3
Helixi139 – 141Combined sources3
Helixi150 – 152Combined sources3
Beta strandi157 – 167Combined sources11
Beta strandi173 – 185Combined sources13
Beta strandi188 – 201Combined sources14
Helixi203 – 207Combined sources5
Beta strandi213 – 216Combined sources4
Helixi220 – 222Combined sources3
Beta strandi226 – 228Combined sources3
Helixi233 – 237Combined sources5
Turni238 – 240Combined sources3
Beta strandi241 – 249Combined sources9
Beta strandi252 – 254Combined sources3
Beta strandi256 – 261Combined sources6
Beta strandi267 – 270Combined sources4
Beta strandi273 – 276Combined sources4
Beta strandi280 – 283Combined sources4
Beta strandi285 – 293Combined sources9
Beta strandi299 – 307Combined sources9
Beta strandi313 – 316Combined sources4
Helixi318 – 325Combined sources8
Beta strandi332 – 334Combined sources3
Turni335 – 338Combined sources4
Beta strandi339 – 343Combined sources5
Beta strandi351 – 355Combined sources5
Beta strandi358 – 362Combined sources5
Helixi364 – 367Combined sources4
Beta strandi368 – 373Combined sources6
Beta strandi377 – 386Combined sources10
Turni387 – 389Combined sources3
Beta strandi390 – 394Combined sources5
Helixi396 – 399Combined sources4
Beta strandi402 – 407Combined sources6
Beta strandi409 – 411Combined sources3
Beta strandi413 – 418Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1E5OX-ray2.05E90-419[»]
1E80X-ray2.05E90-419[»]
1E81X-ray2.05E90-419[»]
1E82X-ray2.05E90-419[»]
1EEDX-ray2.00P90-419[»]
1ENTX-ray1.90E90-419[»]
1EPLX-ray2.00E90-419[»]
1EPMX-ray1.60E90-419[»]
1EPNX-ray1.60E90-419[»]
1EPOX-ray2.00E90-419[»]
1EPPX-ray1.90E90-419[»]
1EPQX-ray1.90E90-419[»]
1EPRX-ray2.30E90-419[»]
1ER8X-ray2.00E90-419[»]
1GKTneutron diffraction2.10A90-419[»]
1GVTX-ray0.98A90-419[»]
1GVUX-ray0.94A90-419[»]
1GVVX-ray1.05A90-419[»]
1GVWX-ray1.00A90-419[»]
1GVXX-ray1.00A90-419[»]
1OD1X-ray1.37A90-419[»]
1OEWX-ray0.90A90-419[»]
1OEXX-ray1.10A90-419[»]
2ER0X-ray3.00E90-419[»]
2ER6X-ray2.00E90-419[»]
2ER7X-ray1.60E90-419[»]
2ER9X-ray2.20E90-419[»]
2JJIX-ray1.57A90-419[»]
2JJJX-ray1.00A90-419[»]
2V00X-ray1.55A90-419[»]
2VS2neutron diffraction2.00A90-419[»]
3ER3X-ray2.00E90-419[»]
3ER5X-ray1.80E90-419[»]
3LZYX-ray1.80A90-419[»]
3PB5X-ray1.90A90-419[»]
3PBDX-ray1.70A90-419[»]
3PBZX-ray1.48A90-419[»]
3PCWX-ray1.25A90-419[»]
3PCZX-ray1.50A90-419[»]
3PGIX-ray1.90A90-419[»]
3PI0X-ray1.64A90-419[»]
3PLDX-ray1.40A90-419[»]
3PLLX-ray1.73A90-419[»]
3PM4X-ray1.68A90-419[»]
3PMUX-ray1.43A90-419[»]
3PMYX-ray1.38A90-419[»]
3PRSX-ray1.38A90-419[»]
3PSYX-ray1.43A90-419[»]
3PWWX-ray1.22A90-419[»]
3Q6YX-ray1.35A90-419[»]
3T6IX-ray1.32A90-419[»]
3T7PX-ray1.35A90-419[»]
3T7QX-ray1.30A90-419[»]
3T7XX-ray1.27A90-419[»]
3URIX-ray2.10A90-419[»]
3URJX-ray1.90A90-419[»]
3URLX-ray2.00A90-419[»]
3WZ6X-ray1.40A90-419[»]
3WZ7X-ray1.90A90-419[»]
3WZ8X-ray1.45A90-419[»]
4APEX-ray2.10A90-419[»]
4ER1X-ray2.00E90-419[»]
4ER2X-ray2.00E90-419[»]
4ER4X-ray2.10E90-419[»]
4KUPX-ray1.31A90-419[»]
4L6BX-ray1.37A90-419[»]
4LAPX-ray1.12A90-419[»]
4LBTX-ray1.25A90-419[»]
4LHHX-ray1.73A90-419[»]
4LP9X-ray1.35A90-419[»]
4Y35X-ray1.46A90-419[»]
4Y36X-ray1.59A90-419[»]
4Y37X-ray1.69A90-419[»]
4Y38X-ray1.10A90-419[»]
4Y39X-ray1.20A90-419[»]
4Y3AX-ray1.17A90-419[»]
4Y3DX-ray1.48A90-419[»]
4Y3EX-ray1.25A90-419[»]
4Y3FX-ray1.40A90-419[»]
4Y3GX-ray1.13A90-419[»]
4Y3HX-ray1.23A90-419[»]
4Y3JX-ray1.31A90-419[»]
4Y3LX-ray1.16A90-419[»]
4Y3MX-ray1.55A90-419[»]
4Y3NX-ray1.34A90-419[»]
4Y3PX-ray1.55A90-419[»]
4Y3QX-ray1.17A90-419[»]
4Y3RX-ray1.13A90-419[»]
4Y3SX-ray1.10A90-419[»]
4Y3TX-ray1.42A90-419[»]
4Y3WX-ray1.58A90-419[»]
4Y3XX-ray1.25A90-419[»]
4Y3YX-ray1.35A90-419[»]
4Y3ZX-ray1.12A90-419[»]
4Y41X-ray1.40A90-419[»]
4Y43X-ray1.48A90-419[»]
4Y44X-ray1.24A90-419[»]
4Y45X-ray1.06A90-419[»]
4Y47X-ray1.19A90-419[»]
4Y48X-ray1.25A90-419[»]
4Y4AX-ray1.28A90-419[»]
4Y4BX-ray1.11A90-419[»]
4Y4DX-ray1.27A90-419[»]
4Y4EX-ray1.30A90-419[»]
4Y4GX-ray1.44A90-419[»]
4Y4JX-ray1.03A90-419[»]
4Y4TX-ray1.30A90-419[»]
4Y4UX-ray1.75A90-419[»]
4Y4WX-ray1.45A90-419[»]
4Y4XX-ray1.67A90-419[»]
4Y4ZX-ray1.48A90-419[»]
4Y50X-ray1.32A90-419[»]
4Y51X-ray1.60A90-419[»]
4Y53X-ray1.62A90-419[»]
4Y54X-ray1.61A90-419[»]
4Y56X-ray1.63A90-419[»]
4Y57X-ray1.49A90-419[»]
4Y58X-ray1.17A90-419[»]
4Y5AX-ray1.45A90-419[»]
4Y5BX-ray1.24A90-419[»]
4Y5CX-ray1.19A90-419[»]
4Y5EX-ray1.12A90-419[»]
4Y5GX-ray1.47A90-419[»]
4Y5KX-ray1.44A90-419[»]
4Y5LX-ray0.99A90-419[»]
4Y5MX-ray1.28A90-419[»]
4Y5NX-ray1.29A90-419[»]
4Y5PX-ray1.23A90-419[»]
4YCKX-ray1.07A90-419[»]
4YCTX-ray1.13A90-419[»]
4YCYX-ray1.70A90-419[»]
4YD3X-ray1.25A90-419[»]
4YD4X-ray1.27A90-419[»]
4YD5X-ray1.21A90-419[»]
4YD6X-ray1.30A90-419[»]
4YD7X-ray1.42A90-419[»]
4ZE6X-ray1.17A90-419[»]
4ZEAX-ray1.20A90-419[»]
5DPZX-ray1.33A90-419[»]
5DQ1X-ray1.49A90-419[»]
5DQ2X-ray1.51A90-419[»]
5DQ4X-ray1.15A90-419[»]
5DQ5X-ray1.47A90-419[»]
5DR0X-ray1.40A90-419[»]
5DR1X-ray1.45A90-419[»]
5DR3X-ray1.24A90-419[»]
5DR4X-ray1.50A90-419[»]
5DR7X-ray1.23A90-419[»]
5DR8X-ray1.47A90-419[»]
5ER1X-ray2.00E90-419[»]
5ER2X-ray1.80E90-419[»]
5HCOX-ray1.17A90-419[»]
5HCTX-ray1.36A1-419[»]
5IS4X-ray1.37A90-419[»]
5ISJX-ray1.65A90-419[»]
5ISKX-ray1.14A90-419[»]
5J25X-ray1.24A90-419[»]
5LWRX-ray1.25A90-419[»]
5LWSX-ray1.03A90-419[»]
5LWTX-ray1.07A90-419[»]
5LWUX-ray1.11A90-419[»]
5MB0X-ray1.15A90-419[»]
5MB3X-ray1.05A90-419[»]
5MB5X-ray0.98A90-419[»]
5MB6X-ray1.20A90-419[»]
5MB7X-ray1.30A90-419[»]
5OYQX-ray1.49A90-419[»]
5OYRX-ray1.49A90-419[»]
5OYSX-ray1.65A90-419[»]
5OYTX-ray1.59A90-419[»]
5OYUX-ray1.25A90-419[»]
5OYVX-ray1.44A90-419[»]
5OYWX-ray1.48A90-419[»]
5OYXX-ray1.65A90-419[»]
5OYYX-ray1.45A90-419[»]
5OYZX-ray1.49A90-419[»]
5OZ0X-ray1.45A90-419[»]
5OZ1X-ray1.48A90-419[»]
5OZ2X-ray1.61A90-419[»]
5OZ3X-ray1.75A90-419[»]
5OZ4X-ray1.48A90-419[»]
5OZ5X-ray1.49A90-419[»]
5OZ6X-ray1.55A90-419[»]
5OZ7X-ray1.61A90-419[»]
5OZ8X-ray1.56A90-419[»]
5OZ9X-ray1.61A90-419[»]
5OZAX-ray1.49A90-419[»]
5OZBX-ray1.49A90-419[»]
5OZCX-ray1.71A90-419[»]
5OZDX-ray1.37A90-419[»]
5OZEX-ray1.24A90-419[»]
5OZFX-ray1.53A90-419[»]
5OZGX-ray1.49A90-419[»]
5OZHX-ray1.49A90-419[»]
5OZIX-ray1.50A90-419[»]
5OZJX-ray1.49A90-419[»]
5OZKX-ray1.33A90-419[»]
5OZLX-ray1.74A90-419[»]
5OZMX-ray1.49A90-419[»]
5OZNX-ray1.49A90-419[»]
5OZOX-ray1.58A90-419[»]
5OZPX-ray1.49A90-419[»]
5OZQX-ray1.50A90-419[»]
5OZRX-ray1.77A90-419[»]
5OZSX-ray1.72A90-419[»]
5OZTX-ray1.80A90-419[»]
5OZUX-ray1.12A90-419[»]
5OZVX-ray1.48A90-419[»]
5OZWX-ray1.54A90-419[»]
5OZXX-ray1.48A90-419[»]
5OZYX-ray1.49A90-419[»]
5OZZX-ray1.53A90-419[»]
5P00X-ray1.51A90-419[»]
5P01X-ray1.51A90-419[»]
5P02X-ray1.49A90-419[»]
5P03X-ray1.49A90-419[»]
5P04X-ray1.67A90-419[»]
5P05X-ray1.60A90-419[»]
5P06X-ray1.32A90-419[»]
5P07X-ray1.62A90-419[»]
5P08X-ray1.60A90-419[»]
5P09X-ray1.61A90-419[»]
5P0AX-ray1.82A90-419[»]
5P0BX-ray1.63A90-419[»]
5P0CX-ray1.82A90-419[»]
5P0DX-ray1.85A90-419[»]
5P0EX-ray1.80A90-419[»]
5P0FX-ray1.25A90-419[»]
5P0GX-ray1.49A90-419[»]
5P0HX-ray1.80A90-419[»]
5P0IX-ray1.15A90-419[»]
5P0JX-ray1.15A90-419[»]
5P0KX-ray1.60A90-419[»]
5P0LX-ray1.51A90-419[»]
5P0MX-ray1.12A90-419[»]
5P0NX-ray1.14A90-419[»]
5P0OX-ray1.33A90-419[»]
5P0PX-ray1.30A90-419[»]
5P0QX-ray1.48A90-419[»]
5P0RX-ray1.25A90-419[»]
5P0SX-ray1.20A90-419[»]
5P0TX-ray1.13A90-419[»]
5P0UX-ray1.46A90-419[»]
5P0VX-ray1.40A90-419[»]
5P0WX-ray1.27A90-419[»]
5P0XX-ray1.27A90-419[»]
5P0YX-ray1.32A90-419[»]
5P0ZX-ray1.26A90-419[»]
5P10X-ray1.49A90-419[»]
5P11X-ray1.38A90-419[»]
5P12X-ray1.55A90-419[»]
5P13X-ray1.40A90-419[»]
5P14X-ray1.24A90-419[»]
5P15X-ray1.41A90-419[»]
5P16X-ray1.64A90-419[»]
5P17X-ray1.40A90-419[»]
5P18X-ray1.35A90-419[»]
5P19X-ray1.13A90-419[»]
5P1AX-ray1.40A90-419[»]
5P1BX-ray1.38A90-419[»]
5P1CX-ray1.35A90-419[»]
5P1DX-ray1.28A90-419[»]
5P1EX-ray1.59A90-419[»]
5P1FX-ray1.26A90-419[»]
5P1GX-ray1.48A90-419[»]
5P1HX-ray1.53A90-419[»]
5P1IX-ray1.34A90-419[»]
5P1JX-ray1.37A90-419[»]
5P1KX-ray1.55A90-419[»]
5P1LX-ray1.25A90-419[»]
5P1MX-ray1.60A90-419[»]
5P1NX-ray1.52A90-419[»]
5P1OX-ray1.51A90-419[»]
5P1PX-ray1.32A90-419[»]
5P1QX-ray1.17A90-419[»]
5P1RX-ray1.33A90-419[»]
5P1SX-ray1.32A90-419[»]
5P1TX-ray1.40A90-419[»]
5P1UX-ray1.50A90-419[»]
5P1VX-ray1.30A90-419[»]
5P1WX-ray1.23A90-419[»]
5P1XX-ray1.20A90-419[»]
5P1YX-ray1.52A90-419[»]
5P1ZX-ray1.46A90-419[»]
5P20X-ray1.44A90-419[»]
5P22X-ray1.31A90-419[»]
5P23X-ray1.71A90-419[»]
5P24X-ray1.71A90-419[»]
5P25X-ray1.26A90-419[»]
5P26X-ray1.41A90-419[»]
5P27X-ray1.45A90-419[»]
5P28X-ray1.34A90-419[»]
5P29X-ray1.48A90-419[»]
5P2AX-ray1.37A90-419[»]
5P2BX-ray1.70A90-419[»]
5P2CX-ray1.75A90-419[»]
5P2DX-ray1.30A90-419[»]
5P2EX-ray1.53A90-419[»]
5P2FX-ray1.80A90-419[»]
5P2GX-ray1.49A90-419[»]
5P2HX-ray1.62A90-419[»]
5P2IX-ray1.43A90-419[»]
5P2JX-ray1.56A90-419[»]
5P2KX-ray1.82A90-419[»]
5P2LX-ray1.12A90-419[»]
5P2MX-ray1.09A90-419[»]
5P2NX-ray1.55A90-419[»]
5P2OX-ray1.12A90-419[»]
5P2QX-ray1.35A90-419[»]
5P2RX-ray1.17A90-419[»]
5P2SX-ray1.08A90-419[»]
5P2TX-ray1.10A90-419[»]
5P2UX-ray1.38A90-419[»]
5P2VX-ray1.32A90-419[»]
5P2WX-ray1.52A90-419[»]
5P2XX-ray1.40A90-419[»]
5P2YX-ray1.64A90-419[»]
5P2ZX-ray1.52A90-419[»]
5P30X-ray1.84A90-419[»]
5P31X-ray1.25A90-419[»]
5P32X-ray1.12A90-419[»]
5P33X-ray1.26A90-419[»]
5P34X-ray1.21A90-419[»]
5P35X-ray1.24A90-419[»]
5P36X-ray1.37A90-419[»]
5P37X-ray1.42A90-419[»]
5P38X-ray1.29A90-419[»]
5P39X-ray1.19A90-419[»]
5P3AX-ray1.18A90-419[»]
5P3BX-ray1.24A90-419[»]
5P3CX-ray1.27A90-419[»]
5P3DX-ray1.18A90-419[»]
5P3EX-ray1.17A90-419[»]
5P3FX-ray1.26A90-419[»]
5P3GX-ray1.39A90-419[»]
5P3HX-ray1.39A90-419[»]
5P3IX-ray1.25A90-419[»]
5P3JX-ray1.34A90-419[»]
5P3KX-ray1.75A90-419[»]
5P3LX-ray1.25A90-419[»]
5P3MX-ray1.19A90-419[»]
5P3NX-ray1.44A90-419[»]
5P3OX-ray1.25A90-419[»]
5P3PX-ray1.46A90-419[»]
5P3QX-ray1.09A90-419[»]
5P3RX-ray1.37A90-419[»]
5P3SX-ray1.17A90-419[»]
5P3TX-ray1.19A90-419[»]
5P3UX-ray1.20A90-419[»]
5P3VX-ray1.47A90-419[»]
5P3WX-ray1.24A90-419[»]
5P3XX-ray1.42A90-419[»]
5P3YX-ray1.22A90-419[»]
5P3ZX-ray1.20A90-419[»]
5P40X-ray1.23A90-419[»]
5P41X-ray1.28A90-419[»]
5P42X-ray1.18A90-419[»]
5P43X-ray1.19A90-419[»]
5P44X-ray1.18A90-419[»]
5P45X-ray1.19A90-419[»]
5P46X-ray1.18A90-419[»]
5P47X-ray1.18A90-419[»]
5P48X-ray1.17A90-419[»]
5P49X-ray1.26A90-419[»]
5P4AX-ray1.35A90-419[»]
5P4BX-ray1.20A90-419[»]
5P4CX-ray1.26A90-419[»]
5P4DX-ray1.25A90-419[»]
5P4EX-ray1.40A90-419[»]
5P4FX-ray1.41A90-419[»]
5P4GX-ray1.16A90-419[»]
5P4HX-ray1.45A90-419[»]
5P4IX-ray1.42A90-419[»]
5P4JX-ray1.52A90-419[»]
5P4KX-ray1.47A90-419[»]
5P4LX-ray1.08A90-419[»]
5P4MX-ray1.07A90-419[»]
5P4NX-ray1.25A90-419[»]
5P4OX-ray1.06A90-419[»]
5P4PX-ray1.57A90-419[»]
5P4QX-ray1.59A90-419[»]
5P4RX-ray1.13A90-419[»]
5P4SX-ray1.31A90-419[»]
5P4TX-ray1.70A90-419[»]
5P4UX-ray1.32A90-419[»]
5P4VX-ray1.33A90-419[»]
5P4WX-ray1.15A90-419[»]
5P4XX-ray1.58A90-419[»]
5P4YX-ray1.41A90-419[»]
5P4ZX-ray1.25A90-419[»]
5P50X-ray1.12A90-419[»]
5P51X-ray1.12A90-419[»]
5P52X-ray1.27A90-419[»]
5P53X-ray1.12A90-419[»]
5P54X-ray1.09A90-419[»]
5P55X-ray1.30A90-419[»]
5P56X-ray1.50A90-419[»]
5P57X-ray1.42A90-419[»]
5P58X-ray1.12A90-419[»]
5P59X-ray1.18A90-419[»]
5P5AX-ray1.27A90-419[»]
5P5BX-ray1.21A90-419[»]
5P5CX-ray1.34A90-419[»]
5P5DX-ray1.58A90-419[»]
5P5EX-ray1.27A90-419[»]
5P5FX-ray1.30A90-419[»]
5P5GX-ray1.66A90-419[»]
5P5HX-ray1.09A90-419[»]
5P5IX-ray1.18A90-419[»]
5P5JX-ray1.17A90-419[»]
5P5KX-ray1.26A90-419[»]
5P5LX-ray1.73A90-419[»]
5P5MX-ray1.18A90-419[»]
5P5NX-ray1.69A90-419[»]
5P5OX-ray1.20A90-419[»]
5P5PX-ray1.09A90-419[»]
5P5QX-ray1.28A90-419[»]
5P5RX-ray1.31A90-419[»]
5P5SX-ray1.14A90-419[»]
5P5TX-ray1.18A90-419[»]
5P5UX-ray1.42A90-419[»]
5P5VX-ray1.06A90-419[»]
5P5WX-ray1.30A90-419[»]
5P5XX-ray1.07A90-419[»]
5P5YX-ray1.14A90-419[»]
5P5ZX-ray1.17A90-419[»]
5P60X-ray1.24A90-419[»]
5P61X-ray1.09A90-419[»]
5P62X-ray1.28A90-419[»]
5P63X-ray1.20A90-419[»]
5P64X-ray1.07A90-419[»]
5P65X-ray1.10A90-419[»]
5P66X-ray1.19A90-419[»]
5P67X-ray1.12A90-419[»]
5P68X-ray1.25A90-419[»]
5P69X-ray1.44A90-419[»]
5P6AX-ray1.16A90-419[»]
5P6BX-ray1.47A90-419[»]
5P6CX-ray1.34A90-419[»]
5P6DX-ray1.44A90-419[»]
5P6EX-ray1.21A90-419[»]
5P6FX-ray1.13A90-419[»]
5P6GX-ray1.09A90-419[»]
5P6HX-ray1.45A90-419[»]
5P6IX-ray1.20A90-419[»]
5P6JX-ray1.26A90-419[»]
5P6KX-ray1.61A90-419[»]
5P6LX-ray1.05A90-419[»]
5P6MX-ray1.34A90-419[»]
5P6NX-ray1.11A90-419[»]
5P6OX-ray1.13A90-419[»]
5P6PX-ray1.28A90-419[»]
5P6QX-ray1.24A90-419[»]
5P6RX-ray1.27A90-419[»]
5P6SX-ray1.34A90-419[»]
5P6TX-ray1.46A90-419[»]
5P6UX-ray1.06A90-419[»]
5P6VX-ray1.28A90-419[»]
5P6WX-ray1.61A90-419[»]
5P6XX-ray1.40A90-419[»]
5P6YX-ray1.18A90-419[»]
5P6ZX-ray1.28A90-419[»]
5P70X-ray1.02A90-419[»]
5P71X-ray1.03A90-419[»]
5P72X-ray1.05A90-419[»]
5P73X-ray1.02A90-419[»]
5P74X-ray1.04A90-419[»]
5P75X-ray1.43A90-419[»]
5P76X-ray1.04A90-419[»]
5P77X-ray1.03A90-419[»]
5P78X-ray1.69A90-419[»]
5P79X-ray1.13A90-419[»]
5P7AX-ray1.25A90-419[»]
5P7BX-ray1.41A90-419[»]
5P7CX-ray1.27A90-419[»]
5P7DX-ray1.17A90-419[»]
5P7EX-ray1.23A90-419[»]
5P7FX-ray1.08A90-419[»]
5P7GX-ray1.10A90-419[»]
5P7HX-ray1.19A90-419[»]
5P7IX-ray1.19A90-419[»]
5P7JX-ray1.31A90-419[»]
5P7KX-ray1.10A90-419[»]
5P7LX-ray1.17A90-419[»]
5P7MX-ray1.33A90-419[»]
5P7NX-ray1.65A90-419[»]
5P7OX-ray1.48A90-419[»]
5P7PX-ray1.44A90-419[»]
5P7QX-ray1.11A90-419[»]
5P7RX-ray1.48A90-419[»]
5P7SX-ray1.19A90-419[»]
5P7TX-ray1.46A90-419[»]
5P7UX-ray1.10A90-419[»]
5P7VX-ray1.28A90-419[»]
5P7WX-ray1.36A90-419[»]
5P7XX-ray1.47A90-419[»]
5P7YX-ray1.65A90-419[»]
5P7ZX-ray1.26A90-419[»]
5P80X-ray1.24A90-419[»]
5P81X-ray1.60A90-419[»]
5P82X-ray1.22A90-419[»]
5P83X-ray1.52A90-419[»]
5P84X-ray1.29A90-419[»]
5P85X-ray1.23A90-419[»]
5P86X-ray1.33A90-419[»]
5P87X-ray1.35A90-419[»]
5P88X-ray1.22A90-419[»]
5P89X-ray1.27A90-419[»]
5P8AX-ray1.27A90-419[»]
5P8BX-ray1.55A90-419[»]
5P8CX-ray1.30A90-419[»]
5P8DX-ray1.18A90-419[»]
5P8EX-ray1.22A90-419[»]
5P8FX-ray1.27A90-419[»]
5P8GX-ray1.28A90-419[»]
5P8HX-ray1.24A90-419[»]
5P8IX-ray1.22A90-419[»]
5P8JX-ray1.33A90-419[»]
5P8KX-ray1.26A90-419[»]
5P8LX-ray1.24A90-419[»]
5P8MX-ray1.20A90-419[»]
5P8NX-ray1.49A90-419[»]
5P8OX-ray1.48A90-419[»]
5P8PX-ray1.22A90-419[»]
5P8QX-ray1.14A90-419[»]
5P8RX-ray1.07A90-419[»]
5P8SX-ray1.11A90-419[»]
5P8TX-ray1.03A90-419[»]
5P8UX-ray1.44A90-419[»]
5P8VX-ray1.58A90-419[»]
ProteinModelPortaliP11838
SMRiP11838
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP11838

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini106 – 417Peptidase A1PROSITE-ProRule annotationAdd BLAST312

Sequence similaritiesi

Belongs to the peptidase A1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

KOiK20737
OMAiINYGPVT

Family and domain databases

CDDicd06097 Aspergillopepsin_like, 1 hit
Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR001969 Aspartic_peptidase_AS
IPR034163 Aspergillopepsin-like_cat_dom
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 2 hits
PS51767 PEPTIDASE_A1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P11838-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPLKNALV TAMLAGGALS SPTKQHVGIP VNASPEVGPG KYSFKQVRNP
60 70 80 90 100
NYKFNGPLSV KKTYLKYGVP IPAWLEDAVQ NSTSGLAERS TGSATTTPID
110 120 130 140 150
SLDDAYITPV QIGTPAQTLN LDFDTGSSDL WVFSSETTAS EVDGQTIYTP
160 170 180 190 200
SKSTTAKLLS GATWSISYGD GSSSSGDVYT DTVSVGGLTV TGQAVESAKK
210 220 230 240 250
VSSSFTEDST IDGLLGLAFS TLNTVSPTQQ KTFFDNAKAS LDSPVFTADL
260 270 280 290 300
GYHAPGTYNF GFIDTTAYTG SITYTAVSTK QGFWEWTSTG YAVGSGTFKS
310 320 330 340 350
TSIDGIADTG TTLLYLPATV VSAYWAQVSG AKSSSSVGGY VFPCSATLPS
360 370 380 390 400
FTFGVGSARI VIPGDYIDFG PISTGSSSCF GGIQSSAGIG INIFGDVALK
410
AAFVVFNGAT TPTLGFASK
Length:419
Mass (Da):43,255
Last modified:October 1, 1993 - v2
Checksum:i262D13F1D2F13296
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63351 Genomic DNA Translation: CAA44952.1
X53997 Genomic DNA Translation: CAA37944.1
PIRiS22136

Genome annotation databases

KEGGiag:CAA44952

Similar proteinsi

Entry informationi

Entry nameiCARP_CRYPA
AccessioniPrimary (citable) accession number: P11838
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1993
Last modified: May 23, 2018
This is version 135 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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