UniProtKB - P11797 (CHIB_SERMA)
Protein
Chitinase B
Gene
chiB
Organism
Serratia marcescens
Status
Functioni
Catalytic activityi
- Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. EC:3.2.1.14
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 144 | Proton donorPROSITE-ProRule annotation | 1 | |
Binding sitei | 145 | ChitooligosaccharidePROSITE-ProRule annotation | 1 | |
Binding sitei | 403 | ChitooligosaccharidePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- carbohydrate binding Source: InterPro
- chitinase activity Source: UniProtKB-EC
- chitin binding Source: InterPro
GO - Biological processi
- chitin catabolic process Source: UniProtKB-KW
- polysaccharide catabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Glycosidase, Hydrolase |
Biological process | Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation |
Enzyme and pathway databases
BioCyci | MetaCyc:MONOMER-20051 |
BRENDAi | 3.2.1.14, 5690 |
SABIO-RKi | P11797 |
Protein family/group databases
CAZyi | CBM5, Carbohydrate-Binding Module Family 5 GH18, Glycoside Hydrolase Family 18 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:chiB |
Organismi | Serratia marcescens |
Taxonomic identifieri | 615 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Yersiniaceae › Serratia |
Pathology & Biotechi
Chemistry databases
ChEMBLi | CHEMBL5348 |
DrugBanki | DB04520, (3s,8ar)-3-(4-Hydroxybenzyl)Hexahydropyrrolo[1,2-a]Pyrazine-1,4-Dione DB02813, 2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone DB03109, 2-acetylamino-2-deoxy-b-D-allopyranose DB04628, Allosamidin DB04404, Allosamizoline DB02414, Cyclo(his-pro) DB04541, Cyclo(prolylglycyl) DB04157, N-[(Aminooxy)Carbonyl]Aniline DB04433, Verpacamide A |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 41 | Add BLAST | 41 | |
ChainiPRO_0000011909 | 42 – 499 | Chitinase BAdd BLAST | 458 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P11797 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P11797 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 42 – 425 | GH18PROSITE-ProRule annotationAdd BLAST | 384 | |
Domaini | 438 – 498 | Chitin-binding type-3Add BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 68 – 69 | Chitooligosaccharide bindingPROSITE-ProRule annotation | 2 | |
Regioni | 95 – 98 | Chitooligosaccharide bindingPROSITE-ProRule annotation | 4 | |
Regioni | 212 – 215 | Chitooligosaccharide bindingPROSITE-ProRule annotation | 4 |
Sequence similaritiesi
Keywords - Domaini
SignalFamily and domain databases
Gene3Di | 3.10.50.10, 1 hit |
InterProi | View protein in InterPro IPR003610, CBM_fam5/12 IPR036573, CBM_sf_5/12 IPR011583, Chitinase_II IPR029070, Chitinase_insertion_sf IPR001223, Glyco_hydro18_cat IPR001579, Glyco_hydro_18_chit_AS IPR017853, Glycoside_hydrolase_SF |
Pfami | View protein in Pfam PF00704, Glyco_hydro_18, 1 hit |
SMARTi | View protein in SMART SM00495, ChtBD3, 1 hit SM00636, Glyco_18, 1 hit |
SUPFAMi | SSF51055, SSF51055, 1 hit SSF51445, SSF51445, 1 hit SSF54556, SSF54556, 1 hit |
PROSITEi | View protein in PROSITE PS01095, GH18_1, 1 hit PS51910, GH18_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P11797-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTRKAVIGY YFIPTNQINN YTETDTSVVP FPVSNITPAK AKQLTHINFS
60 70 80 90 100
FLDINSNLEC AWDPATNDAK ARDVVNRLTA LKAHNPSLRI MFSIGGWYYS
110 120 130 140 150
NDLGVSHANY VNAVKTPAAR TKFAQSCVRI MKDYGFDGVD IDWEYPQAAE
160 170 180 190 200
VDGFIAALQE IRTLLNQQTI ADGRQALPYQ LTIAGAGGAF FLSRYYSKLA
210 220 230 240 250
QIVAPLDYIN LMTYDLAGPW EKITNHQAAL FGDAAGPTFY NALREANLGW
260 270 280 290 300
SWEELTRAFP SPFSLTVDAA VQQHLMMEGV PSAKIVMGVP FYGRAFKGVS
310 320 330 340 350
GGNGGQYSSH STPGEDPYPN ADYWLVGCDE CVRDKDPRIA SYRQLEQMLQ
360 370 380 390 400
GNYGYQRLWN DKTKTPYLYH AQNGLFVTYD DAESFKYKAK YIKQQQLGGV
410 420 430 440 450
MFWHLGQDNR NGDLLAALDR YFNAADYDDS QLDMGTGLRY TGVGPGNLPI
460 470 480 490
MTAPAYVPGT TYAQGALVSY QGYVWQTKWG YITSAPGSDS AWLKVGRLA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X15208 Genomic DNA Translation: CAA33278.1 AB015997 Genomic DNA Translation: BAA31568.1 |
PIRi | S04856 |
RefSeqi | WP_016926761.1, NZ_VOUW01000021.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X15208 Genomic DNA Translation: CAA33278.1 AB015997 Genomic DNA Translation: BAA31568.1 |
PIRi | S04856 |
RefSeqi | WP_016926761.1, NZ_VOUW01000021.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1E6N | X-ray | 2.25 | A/B | 1-497 | [»] | |
1GOI | X-ray | 1.45 | A/B | 1-497 | [»] | |
1H0G | X-ray | 2.00 | A/B | 1-497 | [»] | |
1H0I | X-ray | 2.00 | A/B | 1-497 | [»] | |
1O6I | X-ray | 1.70 | A/B | 1-497 | [»] | |
1OGB | X-ray | 1.85 | A/B | 1-497 | [»] | |
1OGG | X-ray | 1.97 | A/B | 1-497 | [»] | |
3WD0 | X-ray | 1.70 | A | 2-499 | [»] | |
3WD1 | X-ray | 2.30 | A | 2-499 | [»] | |
3WD2 | X-ray | 2.20 | A | 2-499 | [»] | |
3WD3 | X-ray | 2.20 | A | 2-499 | [»] | |
3WD4 | X-ray | 2.00 | A | 2-499 | [»] | |
4Z2G | X-ray | 2.60 | A | 2-499 | [»] | |
4Z2H | X-ray | 2.35 | A | 2-499 | [»] | |
4Z2I | X-ray | 2.00 | A | 2-499 | [»] | |
4Z2J | X-ray | 2.60 | A | 2-499 | [»] | |
4Z2K | X-ray | 2.30 | A | 2-499 | [»] | |
4Z2L | X-ray | 2.30 | A | 2-499 | [»] | |
6JK9 | X-ray | 2.31 | A/B | 3-498 | [»] | |
6JKF | X-ray | 1.99 | A/B | 3-499 | [»] | |
7C34 | X-ray | 1.94 | A/B | 3-498 | [»] | |
SMRi | P11797 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Chemistry databases
BindingDBi | P11797 |
ChEMBLi | CHEMBL5348 |
DrugBanki | DB04520, (3s,8ar)-3-(4-Hydroxybenzyl)Hexahydropyrrolo[1,2-a]Pyrazine-1,4-Dione DB02813, 2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone DB03109, 2-acetylamino-2-deoxy-b-D-allopyranose DB04628, Allosamidin DB04404, Allosamizoline DB02414, Cyclo(his-pro) DB04541, Cyclo(prolylglycyl) DB04157, N-[(Aminooxy)Carbonyl]Aniline DB04433, Verpacamide A |
Protein family/group databases
CAZyi | CBM5, Carbohydrate-Binding Module Family 5 GH18, Glycoside Hydrolase Family 18 |
Enzyme and pathway databases
BioCyci | MetaCyc:MONOMER-20051 |
BRENDAi | 3.2.1.14, 5690 |
SABIO-RKi | P11797 |
Miscellaneous databases
EvolutionaryTracei | P11797 |
Family and domain databases
Gene3Di | 3.10.50.10, 1 hit |
InterProi | View protein in InterPro IPR003610, CBM_fam5/12 IPR036573, CBM_sf_5/12 IPR011583, Chitinase_II IPR029070, Chitinase_insertion_sf IPR001223, Glyco_hydro18_cat IPR001579, Glyco_hydro_18_chit_AS IPR017853, Glycoside_hydrolase_SF |
Pfami | View protein in Pfam PF00704, Glyco_hydro_18, 1 hit |
SMARTi | View protein in SMART SM00495, ChtBD3, 1 hit SM00636, Glyco_18, 1 hit |
SUPFAMi | SSF51055, SSF51055, 1 hit SSF51445, SSF51445, 1 hit SSF54556, SSF54556, 1 hit |
PROSITEi | View protein in PROSITE PS01095, GH18_1, 1 hit PS51910, GH18_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CHIB_SERMA | |
Accessioni | P11797Primary (citable) accession number: P11797 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1989 |
Last sequence update: | October 1, 1989 | |
Last modified: | April 7, 2021 | |
This is version 123 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families