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Entry version 112 (11 Dec 2019)
Sequence version 2 (28 Nov 2002)
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Protein

Levansucrase

Gene

ftf

Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei245SubstrateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei246NucleophileBy similarity1
Binding sitei315SubstrateBy similarity1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei400Transition state stabilizerBy similarity1
Active sitei499Proton donor/acceptorBy similarity1
Binding sitei517SubstrateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
SMUT210007:G1FZX-1915-MONOMER

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GH68 Glycoside Hydrolase Family 68

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Levansucrase (EC:2.4.1.10)
Alternative name(s):
Beta-D-fructofuranosyl transferase
Sucrose 6-fructosyl transferase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ftf
Synonyms:sacB
Ordered Locus Names:SMU_2028
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptococcus mutans serotype c (strain ATCC 700610 / UA159)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri210007 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002512 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 34Add BLAST34
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001225035 – 795LevansucraseAdd BLAST761

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P11701

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
210007.SMU_2028

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P11701

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni399 – 400Substrate bindingBy similarity2
Regioni497 – 499Substrate bindingBy similarity3

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 68 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105EDQ Bacteria
ENOG410XR0E LUCA

KEGG Orthology (KO)

More...
KOi
K00692

Identification of Orthologs from Complete Genome Data

More...
OMAi
WIWDESS

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08997 GH68, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.115.10.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003469 Glyco_hydro_68
IPR023296 Glyco_hydro_beta-prop_sf
IPR022263 KxYKxGKxW

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02435 Glyco_hydro_68, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF75005 SSF75005, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03715 KxYKxGKxW, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P11701-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METKVRKKMY KKGKFWVVAT ITTAMLTGIG LSSVQADEAN STQVSSELAE
60 70 80 90 100
RSQVQENTTA SSSAAENQDK TEVKETPSTN PAAATVENTD QTTKVITDNA
110 120 130 140 150
AVESKASKTK DQAATVTKTS ASTPEVGQTN EKAKATKEAD ITTPKNTIDE
160 170 180 190 200
YGLTEQARKI ATEAGINLSS LTQKQVEALN KVKLTSDAQT GHQMTYQEFD
210 220 230 240 250
KIAQTLIAQD ERYAIPYFNA KAIKNMKAAT TRDAQTGQIA DLDVWDSWPV
260 270 280 290 300
QDAKTGEVIN WNGYQLVVAM MGIPNTNDNH IYLLYNKYGD NNFDHWKNAG
310 320 330 340 350
SIFGYNETPL TQEWSGSATV NEDGSLQLFY TKVDTSDKNS NNQRLATATV
360 370 380 390 400
NLGFDDQDVR ILSVENDKVL TPEGGDGYHY QSYQQWRSTF TGADNIAMRD
410 420 430 440 450
PHVIEDENGD RYLVFEASTG TENYQGEDQI YNFTNYGGSS AYNVKSLFRF
460 470 480 490 500
LDDQDMYNRA SWANAAIGIL KLKGDKKTPE VDQFYTPLLS STMVSDELER
510 520 530 540 550
PNVVKLGDKY YLFTASRLNH GSNNDAWNKA NEVVGDNVVM LGYVSDQLTN
560 570 580 590 600
GYKPLNNSGV VLTASVPADW RTATYSYYAV PVAGSSDTLL MTAYMTNRNE
610 620 630 640 650
VAGKGKNSTW APSFLIQVLP DGTTKVLAEM TQQGDWIWDE SSRTTDTVGT
660 670 680 690 700
LDTAYLPGEN DGYIDWNVIG GYGLKPHTPG QYQPTVPSTP IHTDDIISFE
710 720 730 740 750
VSFDGHLVIK PVKVNNDSAG RIDQSRNSGG SLNVAFNVYA GGNISVKPSQ
760 770 780 790
KSINNTKETK KAHHVSTEKK QKKGNSFFAA LLALFSAFCV SIGFK
Length:795
Mass (Da):87,385
Last modified:November 28, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4012469148B34914
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti69D → A in AAA88584 (PubMed:2828325).Curated1
Sequence conflicti74K → Q in AAA88584 (PubMed:2828325).Curated1
Sequence conflicti120S → A in AAA88584 (PubMed:2828325).Curated1
Sequence conflicti131E → EKD in AAA88584 (PubMed:2828325).Curated1
Sequence conflicti375 – 377GDG → VMA in AAA88584 (PubMed:2828325).Curated3
Sequence conflicti641S → P in AAA88584 (PubMed:2828325).Curated1
Sequence conflicti739Y → S in AAA88584 (PubMed:2828325).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M18954 Genomic DNA Translation: AAA88584.1
AE014133 Genomic DNA Translation: AAN59631.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B28551

NCBI Reference Sequences

More...
RefSeqi
NP_722325.1, NC_004350.2
WP_002262343.1, NC_004350.2

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAN59631; AAN59631; SMU_2028

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1029219

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
smu:SMU_2028

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|210007.7.peg.1808

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M18954 Genomic DNA Translation: AAA88584.1
AE014133 Genomic DNA Translation: AAN59631.1
PIRiB28551
RefSeqiNP_722325.1, NC_004350.2
WP_002262343.1, NC_004350.2

3D structure databases

SMRiP11701
ModBaseiSearch...

Protein-protein interaction databases

STRINGi210007.SMU_2028

Protein family/group databases

CAZyiGH68 Glycoside Hydrolase Family 68

Proteomic databases

PRIDEiP11701

Genome annotation databases

EnsemblBacteriaiAAN59631; AAN59631; SMU_2028
GeneIDi1029219
KEGGismu:SMU_2028
PATRICifig|210007.7.peg.1808

Phylogenomic databases

eggNOGiENOG4105EDQ Bacteria
ENOG410XR0E LUCA
KOiK00692
OMAiWIWDESS

Enzyme and pathway databases

BioCyciSMUT210007:G1FZX-1915-MONOMER

Family and domain databases

CDDicd08997 GH68, 1 hit
Gene3Di2.115.10.20, 1 hit
InterProiView protein in InterPro
IPR003469 Glyco_hydro_68
IPR023296 Glyco_hydro_beta-prop_sf
IPR022263 KxYKxGKxW
PfamiView protein in Pfam
PF02435 Glyco_hydro_68, 1 hit
SUPFAMiSSF75005 SSF75005, 1 hit
TIGRFAMsiTIGR03715 KxYKxGKxW, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSACB_STRMU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P11701
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: November 28, 2002
Last modified: December 11, 2019
This is version 112 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
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