UniProtKB - P11609 (CD1D1_MOUSE)

BLAST

>sp|P11609|CD1D1_MOUSE Antigen-presenting glycoprotein CD1d1 OS=Mus musculus OX=10090 GN=Cd1d1 PE=1 SV=3
MRYLPWLLLWAFLQVWGQSEAQQKNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSN
DSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSA
GCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQM
LLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSADGHRQLVCHVSGFYPKPVWVMW
MRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYWDAR
QAPVGLIVFIVLIMLVVVGAVVYYIWRRRSAYQDIR

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History
Entry version 176 (07 Nov 2018)
Sequence version 3 (15 Dec 1998)
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Protein

Antigen-presenting glycoprotein CD1d1

Gene

Cd1d1

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.3 Publications

Miscellaneous

During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface.

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Binding siteⁱ	98	GlycolipidCombined sources3 Publications		1

GO - Molecular functionⁱ

cell adhesion molecule binding Source: MGI
endogenous lipid antigen binding
Source: MGI
Inferred from direct assayⁱ
- 14722359
exogenous lipid antigen binding Source: MGI
histone binding Source: MGI
lipid antigen binding Source: MGI
lipopeptide binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
T cell receptor binding
Source: MGI
Inferred from direct assayⁱ
- 22065767

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

antigen processing and presentation
Source: MGI
Inferred from direct assayⁱ
- 11754812
antigen processing and presentation, endogenous lipid antigen via MHC class Ib Source: MGI
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
Source: MGI
Inferred from direct assayⁱ
- 14557411
immune response
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
innate immune response Source: UniProtKB-KW
NK T cell differentiation
Source: CACAO
Inferred from mutant phenotypeⁱ
- 9133426
positive regulation of interferon-gamma biosynthetic process
Source: MGI
Inferred from mutant phenotypeⁱ
- 9133426
positive regulation of interleukin-2 biosynthetic process
Source: MGI
Inferred from direct assayⁱ
positive regulation of interleukin-4 biosynthetic process
Source: MGI
Inferred from direct assayⁱ
- 11754812
- 7538697
positive regulation of macrophage activation
Source: MGI
Inferred from direct assayⁱ
- 21460847
positive regulation of NK T cell activation
Source: MGI
Inferred from direct assayⁱ
positive regulation of NK T cell differentiation
Source: MGI
Inferred from mutant phenotypeⁱ
- 10201995
- 9133426
positive regulation of T cell mediated cytotoxicity
Source: MGI
Inferred from direct assayⁱ
- 10201995
positive regulation of T cell proliferation Source: MGI
positive thymic T cell selection
Source: MGI
Inferred from mutant phenotypeⁱ
- 9133426
regulation of immature T cell proliferation in thymus
Source: CACAO
Inferred from mutant phenotypeⁱ
- 11550008
regulation of immune response
Source: MGI
Inferred from mutant phenotypeⁱ
- 9133426

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Immunity, Innate immunity

Biological process

Immunity, Innate immunity

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Antigen-presenting glycoprotein CD1d1 Alternative name(s): CD_antigen: CD1d.1
Gene namesⁱ	Name:Cd1d1 Synonyms:Cd1.1
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Unplaced

Organism-specific databases

MGIⁱ	MGI:107674 Cd1d1

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	22 – 305	ExtracellularSequence analysisAdd BLAST	284
Transmembraneⁱ	306 – 326	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	327 – 336	CytoplasmicSequence analysis	10

Keywords - Cellular componentⁱ

Cell membrane, Endosome, Lysosome, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 21	Sequence analysisAdd BLAST		21
ChainⁱPRO_0000014591	22 – 336	Antigen-presenting glycoprotein CD1d1Add BLAST		315

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	25	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	38	N-linked (GlcNAc...) asparagine3 Publications	1
Glycosylationⁱ	60	N-linked (GlcNAc...) asparagine3 Publications	1
Disulfide bondⁱ	122 ↔ 186	Combined sources5 Publications
Glycosylationⁱ	128	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	183	N-linked (GlcNAc...) asparagine3 Publications	1
Disulfide bondⁱ	226 ↔ 281	Combined sources5 Publications

Post-translational modificationⁱ

N-glycosylated.5 Publications

Keywords - PTMⁱ

Disulfide bond, Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P11609
PaxDbⁱ	P11609
PeptideAtlas More...PeptideAtlasⁱ	P11609
PRIDEⁱ	P11609

PTM databases

iPTMnetⁱ	P11609
PhosphoSitePlusⁱ	P11609
SwissPalmⁱ	P11609

Expressionⁱ

Tissue specificityⁱ

Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

Gene expression databases

CleanExⁱ	MM_CD1D1

CleanExⁱ

MM_CD1D1

Interactionⁱ

Subunit structureⁱ

Heterodimer with B2M (beta-2-microglobulin). Interacts with MHC II and CD74.6 Publications

GO - Molecular functionⁱ

cell adhesion molecule binding Source: MGI
histone binding Source: MGI
T cell receptor binding
Source: MGI
Inferred from direct assayⁱ
- 22065767

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-6127N
IntActⁱ	P11609, 1 interactor
STRINGⁱ	10090.ENSMUSP00000029717

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	26 – 38	Combined sources	13
Beta strandⁱ	41 – 50	Combined sources	10
Beta strandⁱ	53 – 58	Combined sources	6
Beta strandⁱ	66 – 69	Combined sources	4
Turnⁱ	70 – 75	Combined sources	6
Helixⁱ	78 – 105	Combined sources	28
Turnⁱ	107 – 109	Combined sources	3
Beta strandⁱ	112 – 124	Combined sources	13
Beta strandⁱ	126 – 128	Combined sources	3
Beta strandⁱ	130 – 138	Combined sources	9
Beta strandⁱ	141 – 147	Combined sources	7
Beta strandⁱ	150 – 153	Combined sources	4
Helixⁱ	159 – 161	Combined sources	3
Helixⁱ	162 – 170	Combined sources	9
Helixⁱ	172 – 183	Combined sources	12
Helixⁱ	185 – 196	Combined sources	12
Helixⁱ	198 – 201	Combined sources	4
Beta strandⁱ	208 – 214	Combined sources	7
Beta strandⁱ	217 – 220	Combined sources	4
Beta strandⁱ	222 – 234	Combined sources	13
Beta strandⁱ	237 – 242	Combined sources	6
Beta strandⁱ	250 – 252	Combined sources	3
Beta strandⁱ	256 – 258	Combined sources	3
Turnⁱ	259 – 261	Combined sources	3
Beta strandⁱ	263 – 271	Combined sources	9
Turnⁱ	273 – 278	Combined sources	6
Beta strandⁱ	279 – 284	Combined sources	6
Helixⁱ	286 – 288	Combined sources	3
Beta strandⁱ	293 – 296	Combined sources	4

Show more details

3D structure databases

ProteinModelPortalⁱ	P11609
SMRⁱ	P11609
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ

P11609

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	207 – 297	Ig-likeAdd BLAST		91

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	171 – 174	Glycolipid bindingCombined sources4 Publications		4

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	332 – 335	Internalization signal		4

Keywords - Domainⁱ

Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410ITUC Eukaryota ENOG4111EG6 LUCA
HOGENOMⁱ	HOG000111666
HOVERGENⁱ	HBG004453
InParanoidⁱ	P11609
KEGG Orthology (KO) More...KOⁱ	K06448
PhylomeDBⁱ	P11609
TreeFamⁱ	TF336723

Family and domain databases

Gene3Dⁱ	2.60.40.10, 1 hit 3.30.500.10, 1 hit
InterProⁱ	View protein in InterPro IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR003597 Ig_C1-set IPR011161 MHC_I-like_Ag-recog IPR037055 MHC_I-like_Ag-recog_sf IPR011162 MHC_I/II-like_Ag-recog
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07654 C1-set, 1 hit PF16497 MHC_I_3, 1 hit
SMARTⁱ	View protein in SMART SM00407 IGc1, 1 hit
SUPFAMⁱ	SSF48726 SSF48726, 1 hit SSF54452 SSF54452, 1 hit
PROSITEⁱ	View protein in PROSITE PS50835 IG_LIKE, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show all Align All

P11609-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRYLPWLLLW AFLQVWGQSE AQQKNYTFRC LQMSSFANRS WSRTDSVVWL 
        60         70         80         90        100
GDLQTHRWSN DSATISFTKP WSQGKLSNQQ WEKLQHMFQV YRVSFTRDIQ 
       110        120        130        140        150
ELVKMMSPKE DYPIEIQLSA GCEMYPGNAS ESFLHVAFQG KYVVRFWGTS 
       160        170        180        190        200
WQTVPGAPSW LDLPIKVLNA DQGTSATVQM LLNDTCPLFV RGLLEAGKSD 
       210        220        230        240        250
LEKQEKPVAW LSSVPSSADG HRQLVCHVSG FYPKPVWVMW MRGDQEQQGT 
       260        270        280        290        300
HRGDFLPNAD ETWYLQATLD VEAGEEAGLA CRVKHSSLGG QDIILYWDAR 
       310        320        330 
QAPVGLIVFI VLIMLVVVGA VVYYIWRRRS AYQDIR

Length:336

Mass (Da):38,554

Last modified:December 15, 1998 - v3

Checksum:ⁱE4A666E1942E0114

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

E9Q395	E9Q395_MOUSE	Antigen-presenting glycoprotein CD1... Antigen-presenting glycoprotein CD1d1	Cd1d1	205	Annotation score:
A0A0R4J090	A0A0R4J090_MOUSE	Antigen-presenting glycoprotein CD1... Antigen-presenting glycoprotein CD1d1 (MCG3074, isoform CRA_a)	Cd1d1 mCG_3074	336	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	219	D → H in BAB22206 (PubMed:16141072).Curated	1
Sequence conflictⁱ	219	D → H in CAA31568 (PubMed:2460336).Curated	1
Sequence conflictⁱ	240	W → C in AAA37391 (PubMed:1702817).Curated	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M63695 mRNA Translation: AAA37391.1 AK002582 mRNA Translation: BAB22206.1 X13170 Genomic DNA Translation: CAA31568.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS17449.1
PIRⁱ	I49581 S01297
NCBI Reference Sequences More...RefSeqⁱ	NP_031665.2, NM_007639.3
UniGeneⁱ	Mm.1894

Genome annotation databases

GeneIDⁱ	12479
KEGGⁱ	mmu:12479
UCSC genome browser More...UCSCⁱ	uc012cre.1 mouse

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P11609	Antigen-presenting glycoprotein CD1d2	)	MOUSE		336	UniRef90_P11609
CD1d1		MUSSP		336
CD1d1		MUSMC		335
UPI000A3191AD		MUSCR		336
Antigen-presenting glycoprotein CD1d1		MOUSE		336
+7

Protein	Similar proteins		Species	Score	Length	Source
P11609	Antigen-presenting glycoprotein CD1d2	)	MOUSE		336	UniRef50_P11609
CD1d1		MUSSP		336
CD1d1		MUSMC		335
CD1d molecule		AILME		336
antigen-presenting glycoprotein CD1d		URSMA		246
+25

Cross-referencesⁱ

Web resourcesⁱ

Functional Glycomics Gateway - Glycan Binding

CD1d1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M63695 mRNA Translation: AAA37391.1 AK002582 mRNA Translation: BAB22206.1 X13170 Genomic DNA Translation: CAA31568.1
CCDSⁱ	CCDS17449.1
PIRⁱ	I49581 S01297
RefSeqⁱ	NP_031665.2, NM_007639.3
UniGeneⁱ	Mm.1894

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1CD1	X-ray	2.67	A/C	22-336	[»]
	1Z5L	X-ray	2.20	A/C	19-297	[»]
	1ZHN	X-ray	2.80	A	25-297	[»]
	2AKR	X-ray	1.90	A/C	19-297	[»]
	2FIK	X-ray	1.80	A	19-297	[»]
	2GAZ	X-ray	2.61	A	19-297	[»]
	2Q7Y	X-ray	1.95	A/C	19-297	[»]
	3ARB	X-ray	2.70	A	19-297	[»]
	3ARD	X-ray	3.01	A	19-297	[»]
	3ARE	X-ray	2.80	A	19-297	[»]
	3ARF	X-ray	2.90	A	19-297	[»]
	3ARG	X-ray	3.00	A	19-297	[»]
	3AU1	X-ray	2.50	A	19-297	[»]
	3G08	X-ray	1.60	A	19-297	[»]
	3GML	X-ray	1.70	A	19-297	[»]
	3GMM	X-ray	1.80	A	19-297	[»]
	3GMN	X-ray	1.70	A	19-297	[»]
	3GMO	X-ray	1.60	A	19-297	[»]
	3GMP	X-ray	1.70	A	19-297	[»]
	3GMQ	X-ray	1.80	A	19-297	[»]
	3GMR	X-ray	1.90	A	19-297	[»]
	3HE6	X-ray	2.90	A	19-297	[»]
	3HE7	X-ray	2.80	A	19-297	[»]
	3ILP	X-ray	1.85	A	19-297	[»]
	3ILQ	X-ray	2.05	C	19-297	[»]
	3MA7	X-ray	2.29	A/C	19-297	[»]
	3O8X	X-ray	2.74	A	19-297	[»]
	3O9W	X-ray	2.80	A	19-297	[»]
	3QI9	X-ray	2.30	A	19-297	[»]
	3QUX	X-ray	2.91	A	19-297	[»]
	3QUY	X-ray	2.25	A	19-297	[»]
	3QUZ	X-ray	2.30	A	19-297	[»]
	3RTQ	X-ray	2.80	A	19-297	[»]
	3RUG	X-ray	2.20	A/C	19-297	[»]
	3RZC	X-ray	2.80	A	19-297	[»]
	3SCM	X-ray	2.50	A	19-297	[»]
	3SDA	X-ray	2.80	A	19-297	[»]
	3SDC	X-ray	3.10	A	19-297	[»]
	3SDD	X-ray	3.00	A	19-297	[»]
	3T1F	X-ray	1.70	A	19-297	[»]
	3TA3	X-ray	2.70	A	19-297	[»]
	3TN0	X-ray	3.20	A	19-297	[»]
	3TO4	X-ray	3.10	A	19-297	[»]
	3TVM	X-ray	2.80	A/E	19-297	[»]
	3UBX	X-ray	3.10	A/D	19-297	[»]
	4APQ	X-ray	3.00	A	19-297	[»]
	4EI5	X-ray	3.10	A/E	19-297	[»]
	4ELM	X-ray	3.48	A/C	19-297	[»]
	4IRJ	X-ray	3.00	A	19-297	[»]
	4IRS	X-ray	2.80	A	19-297	[»]
	4MNG	X-ray	3.01	A/C	204-297	[»]
	4MQ7	X-ray	2.60	A	205-297	[»]
	4MX7	X-ray	2.24	A	19-297	[»]
	4Y16	X-ray	2.60	A	19-297	[»]
	4Y2D	X-ray	3.05	A/E	19-297	[»]
	4Y4F	X-ray	3.19	A/E	19-297	[»]
	4Y4H	X-ray	3.10	A/E	19-297	[»]
	4Y4K	X-ray	2.90	A	19-297	[»]
	4ZAK	X-ray	2.82	A	19-297	[»]
	5EFI	X-ray	1.80	A	19-297	[»]
	5FKP	X-ray	1.80	A	19-297	[»]
	5TW2	X-ray	1.75	A	19-297	[»]
	5TW5	X-ray	1.85	A	19-297	[»]
5VCJ	X-ray	3.16	A	19-297	[»]
ProteinModelPortalⁱ	P11609
SMRⁱ	P11609
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

DIPⁱ	DIP-6127N
IntActⁱ	P11609, 1 interactor
STRINGⁱ	10090.ENSMUSP00000029717

PTM databases

iPTMnetⁱ	P11609
PhosphoSitePlusⁱ	P11609
SwissPalmⁱ	P11609

Proteomic databases

MaxQBⁱ	P11609
PaxDbⁱ	P11609
PeptideAtlasⁱ	P11609
PRIDEⁱ	P11609

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	12479
KEGGⁱ	mmu:12479
UCSCⁱ	uc012cre.1 mouse

Organism-specific databases

CTDⁱ	12479
MGIⁱ	MGI:107674 Cd1d1

Phylogenomic databases

eggNOGⁱ	ENOG410ITUC Eukaryota ENOG4111EG6 LUCA
HOGENOMⁱ	HOG000111666
HOVERGENⁱ	HBG004453
InParanoidⁱ	P11609
KOⁱ	K06448
PhylomeDBⁱ	P11609
TreeFamⁱ	TF336723

Miscellaneous databases

EvolutionaryTraceⁱ	P11609
Protein Ontology More...PROⁱ	PR:P11609
SOURCEⁱ	Search...

Gene expression databases

CleanExⁱ	MM_CD1D1

CleanExⁱ

MM_CD1D1

Family and domain databases

Gene3Dⁱ	2.60.40.10, 1 hit 3.30.500.10, 1 hit
InterProⁱ	View protein in InterPro IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR003597 Ig_C1-set IPR011161 MHC_I-like_Ag-recog IPR037055 MHC_I-like_Ag-recog_sf IPR011162 MHC_I/II-like_Ag-recog
Pfamⁱ	View protein in Pfam PF07654 C1-set, 1 hit PF16497 MHC_I_3, 1 hit
SMARTⁱ	View protein in SMART SM00407 IGc1, 1 hit
SUPFAMⁱ	SSF48726 SSF48726, 1 hit SSF54452 SSF54452, 1 hit
PROSITEⁱ	View protein in PROSITE PS50835 IG_LIKE, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CD1D1_MOUSE
Accessionⁱ	P11609Primary (citable) accession number: P11609 Secondary accession number(s): Q91XK9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
	Last sequence update:	December 15, 1998
	Last modified:	November 7, 2018
	This is version 176 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P11609 (CD1D1_MOUSE)

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Antigen-presenting glycoprotein CD1d1

Cd1d1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Lysosome

Plasma membrane

Endosome

Endoplasmic reticulum

Endosome

Lysosome

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

Motif

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

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<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ