UniProtKB - P11495 (K1B_METSE)
Protein
U-metritoxin-Msn1a
Gene
N/A
Organism
Metridium senile (Brown sea anemone) (Frilled sea anemone)
Status
Functioni
Has hemolytic activity.1 Publication
GO - Molecular functioni
- toxin activity Source: UniProtKB-KW
GO - Biological processi
- hemolysis in other organism Source: UniProtKB-KW
Keywordsi
Molecular function | Toxin |
Biological process | Cytolysis, Hemolysis |
Names & Taxonomyi
Protein namesi | Recommended name: U-metritoxin-Msn1a1 PublicationShort name: U-MTTX-Msn1a1 Publication Alternative name(s): Metridin1 Publication |
Organismi | Metridium senile (Brown sea anemone) (Frilled sea anemone) |
Taxonomic identifieri | 6116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Cnidaria › Anthozoa › Hexacorallia › Actiniaria › Nynantheae › Metridiidae › Metridium |
Subcellular locationi
Extracellular region or secreted
- Secreted By similarity
Other locations
- Nematocyst By similarity
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Other locations
- nematocyst Source: UniProtKB-SubCell
Keywords - Cellular componenti
Nematocyst, SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
PeptideiPRO_0000044862 | 1 – 36 | U-metritoxin-Msn1a1 PublicationAdd BLAST | 36 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 4 ↔ 36 | PROSITE-ProRule annotation | ||
Disulfide bondi | 11 ↔ 28 | PROSITE-ProRule annotation | ||
Disulfide bondi | 19 ↔ 32 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 36 | ShKTPROSITE-ProRule annotationAdd BLAST | 33 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 23 – 24 | Crucial for binding to potassium channelsBy similarity | 2 |
Sequence similaritiesi
Family and domain databases
InterProi | View protein in InterPro IPR003582 ShKT_dom |
PROSITEi | View protein in PROSITE PS51670 SHKT, 1 hit |
Cross-referencesi
Sequence databases
PIRi | A27222 |
3D structure databases
ModBasei | Search... |
MobiDBi | Search... |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Family and domain databases
InterProi | View protein in InterPro IPR003582 ShKT_dom |
PROSITEi | View protein in PROSITE PS51670 SHKT, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | K1B_METSE | |
Accessioni | P11495Primary (citable) accession number: P11495 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1989 |
Last sequence update: | October 1, 1989 | |
Last modified: | November 22, 2017 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Animal Toxin Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- SIMILARITY comments
Index of protein domains and families