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UniProtKB - P11245 (ARY2_HUMAN)

Entry version 191 (25 May 2022)
Sequence version 2 (23 Feb 2022)
Previous versions | rss
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Protein

Arylamine N-acetyltransferase 2

Gene

NAT2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei68Acyl-thioester intermediate1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei103Coenzyme A1 Publication1
Binding sitei104Coenzyme A; via amide nitrogen1 Publication1
Active sitei1071
Active sitei1221
Binding sitei208Coenzyme A1 Publication1
Binding sitei214Coenzyme A1 Publication1
Binding sitei287Coenzyme A1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.3.1.5, 2681

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P11245

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-156582, Acetylation

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		P11245

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Arylamine N-acetyltransferase 2 (EC:2.3.1.5)
Alternative name(s):
Arylamide acetylase 2
N-acetyltransferase type 2
Short name:
NAT-2
Polymorphic arylamine N-acetyltransferase
Short name:
PNAT
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NAT2
Synonyms:AAC2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:7646, NAT2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		612182, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P11245

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000156006

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		10

MalaCards human disease database

More...MalaCardsi		NAT2
MIMi243400, phenotype

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...Orphaneti		240887, Isoniazid toxicity

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA18

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P11245, Tbio

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL2194

Drug and drug target database

More...DrugBanki		DB00316, Acetaminophen
DB00945, Acetylsalicylic acid
DB11640, Amifampridine
DB01068, Clonazepam
DB00250, Dapsone
DB04953, Ezogabine
DB00951, Isoniazid
DB12612, Ozanimod
DB09288, Propacetamol
DB01015, Sulfamethoxazole

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		NAT2

Domain mapping of disease mutations (DMDM)

More...DMDMi		114238

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001079051 – 290Arylamine N-acetyltransferase 2Add BLAST290

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P11245

MaxQB - The MaxQuant DataBase

More...MaxQBi		P11245

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P11245

PeptideAtlas

More...PeptideAtlasi		P11245

PRoteomics IDEntifications database

More...PRIDEi		P11245

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		52728

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P11245

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P11245

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000156006, Expressed in right lobe of liver and 107 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P11245, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P11245, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000156006, Group enriched (intestine, liver)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		106528, 23 interactors

Protein interaction database and analysis system

More...IntActi		P11245, 22 interactors

Molecular INTeraction database

More...MINTi		P11245

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000286479

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P11245, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1290
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		P11245

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P11245

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P11245

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni106 – 107Substrate bindingCurated2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the arylamine N-acetyltransferase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RD0D, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_049918_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P11245

Database of Orthologous Groups

More...OrthoDBi		1545569at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P11245

TreeFam database of animal gene trees

More...TreeFami		TF106311

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001447, Arylamine_N-AcTrfase
IPR038765, Papain-like_cys_pep_sf

The PANTHER Classification System

More...PANTHERi		PTHR11786, PTHR11786, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00797, Acetyltransf_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01543, ANATRNSFRASE

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54001, SSF54001, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P11245-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDIEAYFERI GYKNSRNKLD LETLTDILEH QIRAVPFENL NMHCGQAMEL 
        60         70         80         90        100
GLEAIFDHIV RRNRGGWCLQ VNQLLYWALT TIGFQTTMLG GYFYIPPVNK 
       110        120        130        140        150
YSTGMVHLLL QVTIDGRNYI VDAGSGSSSQ MWQPLELISG KDQPQVPCIF 
       160        170        180        190        200
CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE 
       210        220        230        240        250
DFESMNTYLQ TSPTSSFITT SFCSLQTPEG VYCLVGFILT YRKFNYKDNT 
       260        270        280        290
DLVEFKTLTE EEVEEVLRNI FKISLGRNLV PKPGDGSLTI
Length:290
Mass (Da):33,571
Last modified:February 23, 2022 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFAEE3BC2107F000E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7EWF9E7EWF9_HUMAN
Arylamine N-acetyltransferase
NAT2
160Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK51711 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti6Y → D in CAG28559 (Ref. 13) Curated1
Sequence conflicti30H → T AA sequence (PubMed:2924904).Curated1
Sequence conflicti286G → R in AAG34181 (Ref. 9) Curated1

<p>This subsection of the 'Sequence' section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement%5Fin%5Fdisease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

Polymorphisms in NAT2 are the cause of slow and fast acetylation phenotypes [MIMi:243400] and influence drug therapy response and susceptibility to chemical toxicity or carcinogenicity.1 Publication

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01885324L → I2 PublicationsCorresponds to variant dbSNP:rs45477599Ensembl.1
Natural variantiVAR_00460864R → Q in allele NAT2*14A, allele NAT2*14B, allele NAT2*14C, allele NAT2*14D, allele NAT2*14E, allele NAT2*14F and allele NAT2*14G; a slow acetylator. 4 PublicationsCorresponds to variant dbSNP:rs1801279EnsemblClinVar.1
Natural variantiVAR_00907564R → W in allele NAT2*19. Corresponds to variant dbSNP:rs1805158Ensembl.1
Natural variantiVAR_004609114I → T in allele NAT2*5A, allele NAT2*5B, allele NAT2*5C, allele NAT2*5D, allele NAT2*5E, allele NAT2*5F, allele NAT2*14B and allele NAT2*14E; a slow acetylator. 8 PublicationsCorresponds to variant dbSNP:rs1801280EnsemblClinVar.1
Natural variantiVAR_020385122D → N1 PublicationCorresponds to variant dbSNP:rs4986996Ensembl.1
Natural variantiVAR_046905135L → V. Corresponds to variant dbSNP:rs12720065Ensembl.1
Natural variantiVAR_020386137L → F1 PublicationCorresponds to variant dbSNP:rs4986997Ensembl.1
Natural variantiVAR_009076145Q → P in allele NAT2*17. 1 PublicationCorresponds to variant dbSNP:rs72554616Ensembl.1
Natural variantiVAR_028781193T → M1 PublicationCorresponds to variant dbSNP:rs79050330Ensembl.1
Natural variantiVAR_004610197R → Q in allele NAT2*5E, allele NAT2*6A, allele NAT2*6B, allele NAT2*6C, allele NAT2*6D and allele NAT2*14D; a slow acetylator. 5 PublicationsCorresponds to variant dbSNP:rs1799930EnsemblClinVar.1
Natural variantiVAR_028782208Y → H1 PublicationCorresponds to variant dbSNP:rs56387565Ensembl.1
Natural variantiVAR_018854228P → L1 PublicationCorresponds to variant dbSNP:rs45518335Ensembl.1
Natural variantiVAR_004611268R → K in allele NAT2*5A, allele NAT2*5D, allele NAT2*5E, allele NAT2*6A, allele NAT2*6B, allele NAT2*6D, allele NAT2*7A, allele NAT2*7B, NAT2*14A, allele NAT2*14B, allele NAT2*14D, allele NAT2*17, allele NAT2*18, allele NAT2*19. 8 PublicationsCorresponds to variant dbSNP:rs1208Ensembl.1
Natural variantiVAR_061368280V → M. Corresponds to variant dbSNP:rs56393504EnsemblClinVar.1
Natural variantiVAR_009077282K → T in allele NAT2*18. 1 PublicationCorresponds to variant dbSNP:rs56054745Ensembl.1
Natural variantiVAR_004612286G → E in allele NAT2*7A and allele NAT2*7B; a slow acetylator. 4 PublicationsCorresponds to variant dbSNP:rs1799931EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X14672 Genomic DNA Translation: CAA32802.1
D90040 mRNA Translation: BAA14094.1
D90042 mRNA Translation: BAA14096.1
D10870 Genomic DNA Translation: BAA01640.1
D10871 Genomic DNA Translation: BAA01641.1
D10872 Genomic DNA Translation: BAA01642.1
U23052 Genomic DNA Translation: AAA64584.1
U23434 Genomic DNA Translation: AAA64585.1
DQ305496 Genomic DNA Translation: ABC26032.1
DQ305497 Genomic DNA Translation: ABC26033.1
DQ305498 Genomic DNA Translation: ABC26034.1
DQ305499 Genomic DNA Translation: ABC26035.1
DQ305500 Genomic DNA Translation: ABC26036.1
DQ305501 Genomic DNA Translation: ABC26037.1
DQ305502 Genomic DNA Translation: ABC26038.1
DQ305503 Genomic DNA Translation: ABC26039.1
DQ305504 Genomic DNA Translation: ABC26040.1
DQ305505 Genomic DNA Translation: ABC26041.1
DQ305506 Genomic DNA Translation: ABC26042.1
DQ305507 Genomic DNA Translation: ABC26043.1
DQ305508 Genomic DNA Translation: ABC26044.1
DQ305509 Genomic DNA Translation: ABC26045.1
DQ305510 Genomic DNA Translation: ABC26046.1
DQ305511 Genomic DNA Translation: ABC26047.1
DQ305512 Genomic DNA Translation: ABC26048.1
DQ305513 Genomic DNA Translation: ABC26049.1
DQ305514 Genomic DNA Translation: ABC26050.1
DQ305515 Genomic DNA Translation: ABC26051.1
DQ305516 Genomic DNA Translation: ABC26052.1
DQ305517 Genomic DNA Translation: ABC26053.1
DQ305518 Genomic DNA Translation: ABC26054.1
DQ305519 Genomic DNA Translation: ABC26055.1
DQ305520 Genomic DNA Translation: ABC26056.1
DQ305521 Genomic DNA Translation: ABC26057.1
DQ305522 Genomic DNA Translation: ABC26058.1
DQ305523 Genomic DNA Translation: ABC26059.1
DQ305524 Genomic DNA Translation: ABC26060.1
DQ305525 Genomic DNA Translation: ABC26061.1
DQ305526 Genomic DNA Translation: ABC26062.1
DQ305527 Genomic DNA Translation: ABC26063.1
DQ305528 Genomic DNA Translation: ABC26064.1
DQ305529 Genomic DNA Translation: ABC26065.1
DQ305530 Genomic DNA Translation: ABC26066.1
DQ305531 Genomic DNA Translation: ABC26067.1
DQ305532 Genomic DNA Translation: ABC26068.1
DQ305533 Genomic DNA Translation: ABC26069.1
DQ305534 Genomic DNA Translation: ABC26070.1
DQ305535 Genomic DNA Translation: ABC26071.1
DQ305536 Genomic DNA Translation: ABC26072.1
DQ305537 Genomic DNA Translation: ABC26073.1
DQ305538 Genomic DNA Translation: ABC26074.1
DQ305539 Genomic DNA Translation: ABC26075.1
DQ305540 Genomic DNA Translation: ABC26076.1
DQ305541 Genomic DNA Translation: ABC26077.1
DQ305542 Genomic DNA Translation: ABC26078.1
DQ305543 Genomic DNA Translation: ABC26079.1
DQ305544 Genomic DNA Translation: ABC26080.1
DQ305545 Genomic DNA Translation: ABC26081.1
DQ305546 Genomic DNA Translation: ABC26082.1
DQ305547 Genomic DNA Translation: ABC26083.1
DQ305548 Genomic DNA Translation: ABC26084.1
DQ305549 Genomic DNA Translation: ABC26085.1
DQ305550 Genomic DNA Translation: ABC26086.1
DQ305551 Genomic DNA Translation: ABC26087.1
DQ305552 Genomic DNA Translation: ABC26088.1
DQ305553 Genomic DNA Translation: ABC26089.1
DQ305554 Genomic DNA Translation: ABC26090.1
DQ305555 Genomic DNA Translation: ABC26091.1
DQ305556 Genomic DNA Translation: ABC26092.1
DQ305557 Genomic DNA Translation: ABC26093.1
DQ305558 Genomic DNA Translation: ABC26094.1
DQ305559 Genomic DNA Translation: ABC26095.1
DQ305560 Genomic DNA Translation: ABC26096.1
DQ305561 Genomic DNA Translation: ABC26097.1
DQ305562 Genomic DNA Translation: ABC26098.1
DQ305563 Genomic DNA Translation: ABC26099.1
DQ305564 Genomic DNA Translation: ABC26100.1
DQ305565 Genomic DNA Translation: ABC26101.1
DQ305566 Genomic DNA Translation: ABC26102.1
DQ305567 Genomic DNA Translation: ABC26103.1
DQ305568 Genomic DNA Translation: ABC26104.1
DQ305569 Genomic DNA Translation: ABC26105.1
DQ305570 Genomic DNA Translation: ABC26106.1
DQ305571 Genomic DNA Translation: ABC26107.1
DQ305572 Genomic DNA Translation: ABC26108.1
DQ305573 Genomic DNA Translation: ABC26109.1
DQ305574 Genomic DNA Translation: ABC26110.1
DQ305575 Genomic DNA Translation: ABC26111.1
DQ305576 Genomic DNA Translation: ABC26112.1
DQ305577 Genomic DNA Translation: ABC26113.1
DQ305578 Genomic DNA Translation: ABC26114.1
DQ305579 Genomic DNA Translation: ABC26115.1
DQ305580 Genomic DNA Translation: ABC26116.1
DQ305581 Genomic DNA Translation: ABC26117.1
DQ305582 Genomic DNA Translation: ABC26118.1
DQ305583 Genomic DNA Translation: ABC26119.1
DQ305584 Genomic DNA Translation: ABC26120.1
DQ305585 Genomic DNA Translation: ABC26121.1
DQ305586 Genomic DNA Translation: ABC26122.1
DQ305587 Genomic DNA Translation: ABC26123.1
DQ305588 Genomic DNA Translation: ABC26124.1
DQ305589 Genomic DNA Translation: ABC26125.1
DQ305590 Genomic DNA Translation: ABC26126.1
DQ305591 Genomic DNA Translation: ABC26127.1
DQ305592 Genomic DNA Translation: ABC26128.1
DQ305593 Genomic DNA Translation: ABC26129.1
DQ305594 Genomic DNA Translation: ABC26130.1
DQ305595 Genomic DNA Translation: ABC26131.1
DQ305596 Genomic DNA Translation: ABC26132.1
DQ305597 Genomic DNA Translation: ABC26133.1
DQ305598 Genomic DNA Translation: ABC26134.1
DQ305599 Genomic DNA Translation: ABC26135.1
DQ305600 Genomic DNA Translation: ABC26136.1
DQ305601 Genomic DNA Translation: ABC26137.1
DQ305602 Genomic DNA Translation: ABC26138.1
DQ305603 Genomic DNA Translation: ABC26139.1
DQ305604 Genomic DNA Translation: ABC26140.1
DQ305605 Genomic DNA Translation: ABC26141.1
DQ305606 Genomic DNA Translation: ABC26142.1
DQ305607 Genomic DNA Translation: ABC26143.1
DQ305608 Genomic DNA Translation: ABC26144.1
DQ305609 Genomic DNA Translation: ABC26145.1
DQ305610 Genomic DNA Translation: ABC26146.1
DQ305611 Genomic DNA Translation: ABC26147.1
DQ305612 Genomic DNA Translation: ABC26148.1
DQ305613 Genomic DNA Translation: ABC26149.1
DQ305614 Genomic DNA Translation: ABC26150.1
DQ305615 Genomic DNA Translation: ABC26151.1
DQ305616 Genomic DNA Translation: ABC26152.1
DQ305617 Genomic DNA Translation: ABC26153.1
DQ305618 Genomic DNA Translation: ABC26154.1
DQ305619 Genomic DNA Translation: ABC26155.1
DQ305620 Genomic DNA Translation: ABC26156.1
DQ305621 Genomic DNA Translation: ABC26157.1
DQ305622 Genomic DNA Translation: ABC26158.1
DQ305623 Genomic DNA Translation: ABC26159.1
DQ305624 Genomic DNA Translation: ABC26160.1
DQ305625 Genomic DNA Translation: ABC26161.1
DQ305626 Genomic DNA Translation: ABC26162.1
DQ305627 Genomic DNA Translation: ABC26163.1
DQ305628 Genomic DNA Translation: ABC26164.1
DQ305629 Genomic DNA Translation: ABC26165.1
DQ305630 Genomic DNA Translation: ABC26166.1
DQ305631 Genomic DNA Translation: ABC26167.1
DQ305632 Genomic DNA Translation: ABC26168.1
DQ305633 Genomic DNA Translation: ABC26169.1
DQ305634 Genomic DNA Translation: ABC26170.1
DQ305635 Genomic DNA Translation: ABC26171.1
DQ305636 Genomic DNA Translation: ABC26172.1
DQ305637 Genomic DNA Translation: ABC26173.1
DQ305638 Genomic DNA Translation: ABC26174.1
DQ305639 Genomic DNA Translation: ABC26175.1
DQ305640 Genomic DNA Translation: ABC26176.1
DQ305641 Genomic DNA Translation: ABC26177.1
DQ305642 Genomic DNA Translation: ABC26178.1
DQ305643 Genomic DNA Translation: ABC26179.1
DQ305644 Genomic DNA Translation: ABC26180.1
DQ305645 Genomic DNA Translation: ABC26181.1
DQ305646 Genomic DNA Translation: ABC26182.1
DQ305647 Genomic DNA Translation: ABC26183.1
DQ305648 Genomic DNA Translation: ABC26184.1
DQ305649 Genomic DNA Translation: ABC26185.1
DQ305650 Genomic DNA Translation: ABC26186.1
DQ305651 Genomic DNA Translation: ABC26187.1
DQ305652 Genomic DNA Translation: ABC26188.1
DQ305653 Genomic DNA Translation: ABC26189.1
DQ305654 Genomic DNA Translation: ABC26190.1
DQ305655 Genomic DNA Translation: ABC26191.1
U53473 Genomic DNA Translation: AAA98976.1
AF042740 Genomic DNA Translation: AAC03773.1
AF055874 Genomic DNA Translation: AAC14117.1
AF055875 Genomic DNA Translation: AAC14118.1
AF320309 Genomic DNA Translation: AAG34181.1
AF348074 Genomic DNA Translation: AAK51710.1
AF348075 Genomic DNA Translation: AAK51711.1 Frameshift.
AY230251 Genomic DNA Translation: AAO73561.1
AY230252 Genomic DNA Translation: AAO73562.1
CR407631 mRNA Translation: CAG28559.1
AY331807 Genomic DNA Translation: AAP81164.1
AC025062 Genomic DNA No translation available.
AC120051 Genomic DNA No translation available.
BC015878 mRNA Translation: AAH15878.1
BC067218 mRNA Translation: AAH67218.1
M75163 Genomic DNA Translation: AAA59906.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS6008.1

Protein sequence database of the Protein Information Resource

More...PIRi		B34585
S02788

NCBI Reference Sequences

More...RefSeqi		NP_000006.2, NM_000015.2
XP_016868427.1, XM_017012938.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000286479.4; ENSP00000286479.3; ENSG00000156006.5

Database of genes from NCBI RefSeq genomes

More...GeneIDi		10

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:10

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000286479.4; ENSP00000286479.3; NM_000015.3; NP_000006.2

UCSC genome browser

More...UCSCi		uc003wyw.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology
NAT

NAT alleles

NIEHS-SNPs
SHMPD

The Singapore human mutation and polymorphism database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14672 Genomic DNA Translation: CAA32802.1
D90040 mRNA Translation: BAA14094.1
D90042 mRNA Translation: BAA14096.1
D10870 Genomic DNA Translation: BAA01640.1
D10871 Genomic DNA Translation: BAA01641.1
D10872 Genomic DNA Translation: BAA01642.1
U23052 Genomic DNA Translation: AAA64584.1
U23434 Genomic DNA Translation: AAA64585.1
DQ305496 Genomic DNA Translation: ABC26032.1
DQ305497 Genomic DNA Translation: ABC26033.1
DQ305498 Genomic DNA Translation: ABC26034.1
DQ305499 Genomic DNA Translation: ABC26035.1
DQ305500 Genomic DNA Translation: ABC26036.1
DQ305501 Genomic DNA Translation: ABC26037.1
DQ305502 Genomic DNA Translation: ABC26038.1
DQ305503 Genomic DNA Translation: ABC26039.1
DQ305504 Genomic DNA Translation: ABC26040.1
DQ305505 Genomic DNA Translation: ABC26041.1
DQ305506 Genomic DNA Translation: ABC26042.1
DQ305507 Genomic DNA Translation: ABC26043.1
DQ305508 Genomic DNA Translation: ABC26044.1
DQ305509 Genomic DNA Translation: ABC26045.1
DQ305510 Genomic DNA Translation: ABC26046.1
DQ305511 Genomic DNA Translation: ABC26047.1
DQ305512 Genomic DNA Translation: ABC26048.1
DQ305513 Genomic DNA Translation: ABC26049.1
DQ305514 Genomic DNA Translation: ABC26050.1
DQ305515 Genomic DNA Translation: ABC26051.1
DQ305516 Genomic DNA Translation: ABC26052.1
DQ305517 Genomic DNA Translation: ABC26053.1
DQ305518 Genomic DNA Translation: ABC26054.1
DQ305519 Genomic DNA Translation: ABC26055.1
DQ305520 Genomic DNA Translation: ABC26056.1
DQ305521 Genomic DNA Translation: ABC26057.1
DQ305522 Genomic DNA Translation: ABC26058.1
DQ305523 Genomic DNA Translation: ABC26059.1
DQ305524 Genomic DNA Translation: ABC26060.1
DQ305525 Genomic DNA Translation: ABC26061.1
DQ305526 Genomic DNA Translation: ABC26062.1
DQ305527 Genomic DNA Translation: ABC26063.1
DQ305528 Genomic DNA Translation: ABC26064.1
DQ305529 Genomic DNA Translation: ABC26065.1
DQ305530 Genomic DNA Translation: ABC26066.1
DQ305531 Genomic DNA Translation: ABC26067.1
DQ305532 Genomic DNA Translation: ABC26068.1
DQ305533 Genomic DNA Translation: ABC26069.1
DQ305534 Genomic DNA Translation: ABC26070.1
DQ305535 Genomic DNA Translation: ABC26071.1
DQ305536 Genomic DNA Translation: ABC26072.1
DQ305537 Genomic DNA Translation: ABC26073.1
DQ305538 Genomic DNA Translation: ABC26074.1
DQ305539 Genomic DNA Translation: ABC26075.1
DQ305540 Genomic DNA Translation: ABC26076.1
DQ305541 Genomic DNA Translation: ABC26077.1
DQ305542 Genomic DNA Translation: ABC26078.1
DQ305543 Genomic DNA Translation: ABC26079.1
DQ305544 Genomic DNA Translation: ABC26080.1
DQ305545 Genomic DNA Translation: ABC26081.1
DQ305546 Genomic DNA Translation: ABC26082.1
DQ305547 Genomic DNA Translation: ABC26083.1
DQ305548 Genomic DNA Translation: ABC26084.1
DQ305549 Genomic DNA Translation: ABC26085.1
DQ305550 Genomic DNA Translation: ABC26086.1
DQ305551 Genomic DNA Translation: ABC26087.1
DQ305552 Genomic DNA Translation: ABC26088.1
DQ305553 Genomic DNA Translation: ABC26089.1
DQ305554 Genomic DNA Translation: ABC26090.1
DQ305555 Genomic DNA Translation: ABC26091.1
DQ305556 Genomic DNA Translation: ABC26092.1
DQ305557 Genomic DNA Translation: ABC26093.1
DQ305558 Genomic DNA Translation: ABC26094.1
DQ305559 Genomic DNA Translation: ABC26095.1
DQ305560 Genomic DNA Translation: ABC26096.1
DQ305561 Genomic DNA Translation: ABC26097.1
DQ305562 Genomic DNA Translation: ABC26098.1
DQ305563 Genomic DNA Translation: ABC26099.1
DQ305564 Genomic DNA Translation: ABC26100.1
DQ305565 Genomic DNA Translation: ABC26101.1
DQ305566 Genomic DNA Translation: ABC26102.1
DQ305567 Genomic DNA Translation: ABC26103.1
DQ305568 Genomic DNA Translation: ABC26104.1
DQ305569 Genomic DNA Translation: ABC26105.1
DQ305570 Genomic DNA Translation: ABC26106.1
DQ305571 Genomic DNA Translation: ABC26107.1
DQ305572 Genomic DNA Translation: ABC26108.1
DQ305573 Genomic DNA Translation: ABC26109.1
DQ305574 Genomic DNA Translation: ABC26110.1
DQ305575 Genomic DNA Translation: ABC26111.1
DQ305576 Genomic DNA Translation: ABC26112.1
DQ305577 Genomic DNA Translation: ABC26113.1
DQ305578 Genomic DNA Translation: ABC26114.1
DQ305579 Genomic DNA Translation: ABC26115.1
DQ305580 Genomic DNA Translation: ABC26116.1
DQ305581 Genomic DNA Translation: ABC26117.1
DQ305582 Genomic DNA Translation: ABC26118.1
DQ305583 Genomic DNA Translation: ABC26119.1
DQ305584 Genomic DNA Translation: ABC26120.1
DQ305585 Genomic DNA Translation: ABC26121.1
DQ305586 Genomic DNA Translation: ABC26122.1
DQ305587 Genomic DNA Translation: ABC26123.1
DQ305588 Genomic DNA Translation: ABC26124.1
DQ305589 Genomic DNA Translation: ABC26125.1
DQ305590 Genomic DNA Translation: ABC26126.1
DQ305591 Genomic DNA Translation: ABC26127.1
DQ305592 Genomic DNA Translation: ABC26128.1
DQ305593 Genomic DNA Translation: ABC26129.1
DQ305594 Genomic DNA Translation: ABC26130.1
DQ305595 Genomic DNA Translation: ABC26131.1
DQ305596 Genomic DNA Translation: ABC26132.1
DQ305597 Genomic DNA Translation: ABC26133.1
DQ305598 Genomic DNA Translation: ABC26134.1
DQ305599 Genomic DNA Translation: ABC26135.1
DQ305600 Genomic DNA Translation: ABC26136.1
DQ305601 Genomic DNA Translation: ABC26137.1
DQ305602 Genomic DNA Translation: ABC26138.1
DQ305603 Genomic DNA Translation: ABC26139.1
DQ305604 Genomic DNA Translation: ABC26140.1
DQ305605 Genomic DNA Translation: ABC26141.1
DQ305606 Genomic DNA Translation: ABC26142.1
DQ305607 Genomic DNA Translation: ABC26143.1
DQ305608 Genomic DNA Translation: ABC26144.1
DQ305609 Genomic DNA Translation: ABC26145.1
DQ305610 Genomic DNA Translation: ABC26146.1
DQ305611 Genomic DNA Translation: ABC26147.1
DQ305612 Genomic DNA Translation: ABC26148.1
DQ305613 Genomic DNA Translation: ABC26149.1
DQ305614 Genomic DNA Translation: ABC26150.1
DQ305615 Genomic DNA Translation: ABC26151.1
DQ305616 Genomic DNA Translation: ABC26152.1
DQ305617 Genomic DNA Translation: ABC26153.1
DQ305618 Genomic DNA Translation: ABC26154.1
DQ305619 Genomic DNA Translation: ABC26155.1
DQ305620 Genomic DNA Translation: ABC26156.1
DQ305621 Genomic DNA Translation: ABC26157.1
DQ305622 Genomic DNA Translation: ABC26158.1
DQ305623 Genomic DNA Translation: ABC26159.1
DQ305624 Genomic DNA Translation: ABC26160.1
DQ305625 Genomic DNA Translation: ABC26161.1
DQ305626 Genomic DNA Translation: ABC26162.1
DQ305627 Genomic DNA Translation: ABC26163.1
DQ305628 Genomic DNA Translation: ABC26164.1
DQ305629 Genomic DNA Translation: ABC26165.1
DQ305630 Genomic DNA Translation: ABC26166.1
DQ305631 Genomic DNA Translation: ABC26167.1
DQ305632 Genomic DNA Translation: ABC26168.1
DQ305633 Genomic DNA Translation: ABC26169.1
DQ305634 Genomic DNA Translation: ABC26170.1
DQ305635 Genomic DNA Translation: ABC26171.1
DQ305636 Genomic DNA Translation: ABC26172.1
DQ305637 Genomic DNA Translation: ABC26173.1
DQ305638 Genomic DNA Translation: ABC26174.1
DQ305639 Genomic DNA Translation: ABC26175.1
DQ305640 Genomic DNA Translation: ABC26176.1
DQ305641 Genomic DNA Translation: ABC26177.1
DQ305642 Genomic DNA Translation: ABC26178.1
DQ305643 Genomic DNA Translation: ABC26179.1
DQ305644 Genomic DNA Translation: ABC26180.1
DQ305645 Genomic DNA Translation: ABC26181.1
DQ305646 Genomic DNA Translation: ABC26182.1
DQ305647 Genomic DNA Translation: ABC26183.1
DQ305648 Genomic DNA Translation: ABC26184.1
DQ305649 Genomic DNA Translation: ABC26185.1
DQ305650 Genomic DNA Translation: ABC26186.1
DQ305651 Genomic DNA Translation: ABC26187.1
DQ305652 Genomic DNA Translation: ABC26188.1
DQ305653 Genomic DNA Translation: ABC26189.1
DQ305654 Genomic DNA Translation: ABC26190.1
DQ305655 Genomic DNA Translation: ABC26191.1
U53473 Genomic DNA Translation: AAA98976.1
AF042740 Genomic DNA Translation: AAC03773.1
AF055874 Genomic DNA Translation: AAC14117.1
AF055875 Genomic DNA Translation: AAC14118.1
AF320309 Genomic DNA Translation: AAG34181.1
AF348074 Genomic DNA Translation: AAK51710.1
AF348075 Genomic DNA Translation: AAK51711.1 Frameshift.
AY230251 Genomic DNA Translation: AAO73561.1
AY230252 Genomic DNA Translation: AAO73562.1
CR407631 mRNA Translation: CAG28559.1
AY331807 Genomic DNA Translation: AAP81164.1
AC025062 Genomic DNA No translation available.
AC120051 Genomic DNA No translation available.
BC015878 mRNA Translation: AAH15878.1
BC067218 mRNA Translation: AAH67218.1
M75163 Genomic DNA Translation: AAA59906.1
CCDSiCCDS6008.1
PIRiB34585
S02788
RefSeqiNP_000006.2, NM_000015.2
XP_016868427.1, XM_017012938.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PFRX-ray1.92A/B2-290[»]
AlphaFoldDBiP11245
SMRiP11245
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi106528, 23 interactors
IntActiP11245, 22 interactors
MINTiP11245
STRINGi9606.ENSP00000286479

Chemistry databases

ChEMBLiCHEMBL2194
DrugBankiDB00316, Acetaminophen
DB00945, Acetylsalicylic acid
DB11640, Amifampridine
DB01068, Clonazepam
DB00250, Dapsone
DB04953, Ezogabine
DB00951, Isoniazid
DB12612, Ozanimod
DB09288, Propacetamol
DB01015, Sulfamethoxazole

PTM databases

iPTMnetiP11245
PhosphoSitePlusiP11245

Genetic variation databases

BioMutaiNAT2
DMDMi114238

Proteomic databases

MassIVEiP11245
MaxQBiP11245
PaxDbiP11245
PeptideAtlasiP11245
PRIDEiP11245
ProteomicsDBi52728

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		22356, 259 antibodies from 27 providers

The DNASU plasmid repository

More...DNASUi		10

Genome annotation databases

EnsembliENST00000286479.4; ENSP00000286479.3; ENSG00000156006.5
GeneIDi10
KEGGihsa:10
MANE-SelectiENST00000286479.4; ENSP00000286479.3; NM_000015.3; NP_000006.2
UCSCiuc003wyw.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		10
DisGeNETi10

GeneCards: human genes, protein and diseases

More...GeneCardsi		NAT2
HGNCiHGNC:7646, NAT2
HPAiENSG00000156006, Group enriched (intestine, liver)
MalaCardsiNAT2
MIMi243400, phenotype
612182, gene
neXtProtiNX_P11245
Orphaneti240887, Isoniazid toxicity
PharmGKBiPA18
VEuPathDBiHostDB:ENSG00000156006

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502RD0D, Eukaryota
HOGENOMiCLU_049918_3_0_1
InParanoidiP11245
OrthoDBi1545569at2759
PhylomeDBiP11245
TreeFamiTF106311

Enzyme and pathway databases

BRENDAi2.3.1.5, 2681
PathwayCommonsiP11245
ReactomeiR-HSA-156582, Acetylation
SignaLinkiP11245

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		10, 11 hits in 1064 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		NAT2, human
EvolutionaryTraceiP11245

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		N-acetyltransferase_2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		10
PharosiP11245, Tbio

Protein Ontology

More...PROi		PR:P11245
RNActiP11245, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000156006, Expressed in right lobe of liver and 107 other tissues
ExpressionAtlasiP11245, baseline and differential
GenevisibleiP11245, HS

Family and domain databases

InterProiView protein in InterPro
IPR001447, Arylamine_N-AcTrfase
IPR038765, Papain-like_cys_pep_sf
PANTHERiPTHR11786, PTHR11786, 1 hit
PfamiView protein in Pfam
PF00797, Acetyltransf_2, 1 hit
PRINTSiPR01543, ANATRNSFRASE
SUPFAMiSSF54001, SSF54001, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARY2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P11245
Secondary accession number(s): O43637
, O60654, O60655, Q13146, Q16697, Q2MLE4, Q2MLF5, Q2MLG8, Q2MLJ6, Q2MLK4, Q2MLK6, Q2MLN7, Q6LET4, Q86XS0, Q86XS1, Q96KY8, Q96T64, Q96T65, Q9H220
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: February 23, 2022
Last modified: May 25, 2022
This is version 191 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families
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