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Protein

Arylamine N-acetyltransferase 2

Gene

NAT2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei68Acyl-thioester intermediate1
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei103Coenzyme A1 Publication1
Binding sitei104Coenzyme A; via amide nitrogen1 Publication1
Active sitei1071
Active sitei1221
Binding sitei208Coenzyme A1 Publication1
Binding sitei214Coenzyme A1 Publication1
Binding sitei287Coenzyme A1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • arylamine N-acetyltransferase activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.3.1.5 2681

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156582 Acetylation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Arylamine N-acetyltransferase 2 (EC:2.3.1.5)
Alternative name(s):
Arylamide acetylase 2
N-acetyltransferase type 2
Short name:
NAT-2
Polymorphic arylamine N-acetyltransferase
Short name:
PNAT
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NAT2
Synonyms:AAC2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000156006.4

Human Gene Nomenclature Database

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HGNCi
HGNC:7646 NAT2

Online Mendelian Inheritance in Man (OMIM)

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MIMi
612182 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P11245

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

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DisGeNETi
10

MalaCards human disease database

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MalaCardsi
NAT2
MIMi243400 phenotype

Orphanet; a database dedicated to information on rare diseases and orphan drugs

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Orphaneti
240887 Isoniazid toxicity

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA18

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

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ChEMBLi
CHEMBL2194

Drug and drug target database

More...
DrugBanki
DB00316 Acetaminophen
DB01068 Clonazepam
DB00250 Dapsone
DB04953 Ezogabine
DB00951 Isoniazid
DB01015 Sulfamethoxazole

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NAT2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
114238

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001079051 – 290Arylamine N-acetyltransferase 2Add BLAST290

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
P11245

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P11245

PeptideAtlas

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PeptideAtlasi
P11245

PRoteomics IDEntifications database

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PRIDEi
P11245

ProteomicsDB human proteome resource

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ProteomicsDBi
52728

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
P11245

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
P11245

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000156006 Expressed in 83 organ(s), highest expression level in liver

CleanEx database of gene expression profiles

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CleanExi
HS_NAT2

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P11245 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P11245 HS

Organism-specific databases

Human Protein Atlas

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HPAi
HPA043704

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
106528, 20 interactors

Protein interaction database and analysis system

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IntActi
P11245, 19 interactors

Molecular INTeraction database

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MINTi
P11245

STRING: functional protein association networks

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STRINGi
9606.ENSP00000286479

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1290
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PFRX-ray1.92A/B2-290[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P11245

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P11245

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P11245

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni106 – 107Substrate bindingCurated2

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IFD6 Eukaryota
COG2162 LUCA

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG000165

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P11245

KEGG Orthology (KO)

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KOi
K00622

Database of Orthologous Groups

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OrthoDBi
1545569at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
P11245

TreeFam database of animal gene trees

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TreeFami
TF106311

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR001447 Arylamine_N-AcTrfase
IPR038765 Papain_like_cys_pep_sf

The PANTHER Classification System

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PANTHERi
PTHR11786 PTHR11786, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00797 Acetyltransf_2, 1 hit

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR01543 ANATRNSFRASE

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54001 SSF54001, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P11245-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDIEAYFERI GYKNSRNKLD LETLTDILEH QIRAVPFENL NMHCGQAMEL
60 70 80 90 100
GLEAIFDHIV RRNRGGWCLQ VNQLLYWALT TIGFQTTMLG GYFYIPPVNK
110 120 130 140 150
YSTGMVHLLL QVTIDGRNYI VDAGSGSSSQ MWQPLELISG KDQPQVPCIF
160 170 180 190 200
CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE
210 220 230 240 250
DFESMNTYLQ TSPTSSFITT SFCSLQTPEG VYCLVGFILT YRKFNYKDNT
260 270 280 290
DLVEFKTLTE EEVEEVLKNI FKISLGRNLV PKPGDGSLTI
Length:290
Mass (Da):33,542
Last modified:July 1, 1989 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i63EE3BC2107F12B9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7EWF9E7EWF9_HUMAN
Arylamine N-acetyltransferase 2
NAT2
160Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK51711 differs from that shown. Reason: Frameshift at position 287.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti6Y → D in CAG28559 (Ref. 13) Curated1
Sequence conflicti30H → T AA sequence (PubMed:2924904).Curated1
Sequence conflicti286G → R in AAG34181 (Ref. 9) Curated1

<p>This subsection of the ‘Sequence’ section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

Polymorphisms in NAT2 are the cause of slow and fast acetylation phenotypes [MIMi:243400] and influence drug therapy response and susceptibility to chemical toxicity or carcinogenicity.1 Publication

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01885324L → I2 PublicationsCorresponds to variant dbSNP:rs45477599Ensembl.1
Natural variantiVAR_00460864R → Q in allele NAT2*14A, allele NAT2*14B, allele NAT2*14C, allele NAT2*14D, allele NAT2*14E, allele NAT2*14F and allele NAT2*14G; a slow acetylator. 4 PublicationsCorresponds to variant dbSNP:rs1801279EnsemblClinVar.1
Natural variantiVAR_00907564R → W in allele NAT2*19. Corresponds to variant dbSNP:rs1805158Ensembl.1
Natural variantiVAR_004609114I → T in allele NAT2*5A, allele NAT2*5B, allele NAT2*5C, allele NAT2*5D, allele NAT2*5E, allele NAT2*5F, allele NAT2*14B and allele NAT2*14E; a slow acetylator. 8 PublicationsCorresponds to variant dbSNP:rs1801280EnsemblClinVar.1
Natural variantiVAR_020385122D → N1 PublicationCorresponds to variant dbSNP:rs4986996Ensembl.1
Natural variantiVAR_046905135L → V. Corresponds to variant dbSNP:rs12720065Ensembl.1
Natural variantiVAR_020386137L → F1 PublicationCorresponds to variant dbSNP:rs4986997Ensembl.1
Natural variantiVAR_009076145Q → P in allele NAT2*17. 1 Publication1
Natural variantiVAR_028781193T → M1 Publication1
Natural variantiVAR_004610197R → Q in allele NAT2*5E, allele NAT2*6A, allele NAT2*6B, allele NAT2*6C, allele NAT2*6D and allele NAT2*14D; a slow acetylator. 5 PublicationsCorresponds to variant dbSNP:rs1799930EnsemblClinVar.1
Natural variantiVAR_028782208Y → H1 PublicationCorresponds to variant dbSNP:rs56387565Ensembl.1
Natural variantiVAR_018854228P → L1 PublicationCorresponds to variant dbSNP:rs45518335Ensembl.1
Natural variantiVAR_004611268K → R in allele NAT2*5B, allele NAT2*5C, allele NAT2*5F, allele NAT2*6C, allele NAT2*12A, allele NAT2*14B, allele NAT2*14C, allele NAT2*14E, allele NAT2*14F and allele NAT2*14G. 8 PublicationsCorresponds to variant dbSNP:rs1208Ensembl.1
Natural variantiVAR_061368280V → M. Corresponds to variant dbSNP:rs56393504Ensembl.1
Natural variantiVAR_009077282K → T in allele NAT2*18. 1 PublicationCorresponds to variant dbSNP:rs56054745Ensembl.1
Natural variantiVAR_004612286G → E in allele NAT2*7A and allele NAT2*7B; a slow acetylator. 4 PublicationsCorresponds to variant dbSNP:rs1799931EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X14672 Genomic DNA Translation: CAA32802.1
D90040 mRNA Translation: BAA14094.1
D90042 mRNA Translation: BAA14096.1
D10870 Genomic DNA Translation: BAA01640.1
D10871 Genomic DNA Translation: BAA01641.1
D10872 Genomic DNA Translation: BAA01642.1
U23052 Genomic DNA Translation: AAA64584.1
U23434 Genomic DNA Translation: AAA64585.1
DQ305496 Genomic DNA Translation: ABC26032.1
DQ305497 Genomic DNA Translation: ABC26033.1
DQ305498 Genomic DNA Translation: ABC26034.1
DQ305499 Genomic DNA Translation: ABC26035.1
DQ305500 Genomic DNA Translation: ABC26036.1
DQ305501 Genomic DNA Translation: ABC26037.1
DQ305502 Genomic DNA Translation: ABC26038.1
DQ305503 Genomic DNA Translation: ABC26039.1
DQ305504 Genomic DNA Translation: ABC26040.1
DQ305505 Genomic DNA Translation: ABC26041.1
DQ305506 Genomic DNA Translation: ABC26042.1
DQ305507 Genomic DNA Translation: ABC26043.1
DQ305508 Genomic DNA Translation: ABC26044.1
DQ305509 Genomic DNA Translation: ABC26045.1
DQ305510 Genomic DNA Translation: ABC26046.1
DQ305511 Genomic DNA Translation: ABC26047.1
DQ305512 Genomic DNA Translation: ABC26048.1
DQ305513 Genomic DNA Translation: ABC26049.1
DQ305514 Genomic DNA Translation: ABC26050.1
DQ305515 Genomic DNA Translation: ABC26051.1
DQ305516 Genomic DNA Translation: ABC26052.1
DQ305517 Genomic DNA Translation: ABC26053.1
DQ305518 Genomic DNA Translation: ABC26054.1
DQ305519 Genomic DNA Translation: ABC26055.1
DQ305520 Genomic DNA Translation: ABC26056.1
DQ305521 Genomic DNA Translation: ABC26057.1
DQ305522 Genomic DNA Translation: ABC26058.1
DQ305523 Genomic DNA Translation: ABC26059.1
DQ305524 Genomic DNA Translation: ABC26060.1
DQ305525 Genomic DNA Translation: ABC26061.1
DQ305526 Genomic DNA Translation: ABC26062.1
DQ305527 Genomic DNA Translation: ABC26063.1
DQ305528 Genomic DNA Translation: ABC26064.1
DQ305529 Genomic DNA Translation: ABC26065.1
DQ305530 Genomic DNA Translation: ABC26066.1
DQ305531 Genomic DNA Translation: ABC26067.1
DQ305532 Genomic DNA Translation: ABC26068.1
DQ305533 Genomic DNA Translation: ABC26069.1
DQ305534 Genomic DNA Translation: ABC26070.1
DQ305535 Genomic DNA Translation: ABC26071.1
DQ305536 Genomic DNA Translation: ABC26072.1
DQ305537 Genomic DNA Translation: ABC26073.1
DQ305538 Genomic DNA Translation: ABC26074.1
DQ305539 Genomic DNA Translation: ABC26075.1
DQ305540 Genomic DNA Translation: ABC26076.1
DQ305541 Genomic DNA Translation: ABC26077.1
DQ305542 Genomic DNA Translation: ABC26078.1
DQ305543 Genomic DNA Translation: ABC26079.1
DQ305544 Genomic DNA Translation: ABC26080.1
DQ305545 Genomic DNA Translation: ABC26081.1
DQ305546 Genomic DNA Translation: ABC26082.1
DQ305547 Genomic DNA Translation: ABC26083.1
DQ305548 Genomic DNA Translation: ABC26084.1
DQ305549 Genomic DNA Translation: ABC26085.1
DQ305550 Genomic DNA Translation: ABC26086.1
DQ305551 Genomic DNA Translation: ABC26087.1
DQ305552 Genomic DNA Translation: ABC26088.1
DQ305553 Genomic DNA Translation: ABC26089.1
DQ305554 Genomic DNA Translation: ABC26090.1
DQ305555 Genomic DNA Translation: ABC26091.1
DQ305556 Genomic DNA Translation: ABC26092.1
DQ305557 Genomic DNA Translation: ABC26093.1
DQ305558 Genomic DNA Translation: ABC26094.1
DQ305559 Genomic DNA Translation: ABC26095.1
DQ305560 Genomic DNA Translation: ABC26096.1
DQ305561 Genomic DNA Translation: ABC26097.1
DQ305562 Genomic DNA Translation: ABC26098.1
DQ305563 Genomic DNA Translation: ABC26099.1
DQ305564 Genomic DNA Translation: ABC26100.1
DQ305565 Genomic DNA Translation: ABC26101.1
DQ305566 Genomic DNA Translation: ABC26102.1
DQ305567 Genomic DNA Translation: ABC26103.1
DQ305568 Genomic DNA Translation: ABC26104.1
DQ305569 Genomic DNA Translation: ABC26105.1
DQ305570 Genomic DNA Translation: ABC26106.1
DQ305571 Genomic DNA Translation: ABC26107.1
DQ305572 Genomic DNA Translation: ABC26108.1
DQ305573 Genomic DNA Translation: ABC26109.1
DQ305574 Genomic DNA Translation: ABC26110.1
DQ305575 Genomic DNA Translation: ABC26111.1
DQ305576 Genomic DNA Translation: ABC26112.1
DQ305577 Genomic DNA Translation: ABC26113.1
DQ305578 Genomic DNA Translation: ABC26114.1
DQ305579 Genomic DNA Translation: ABC26115.1
DQ305580 Genomic DNA Translation: ABC26116.1
DQ305581 Genomic DNA Translation: ABC26117.1
DQ305582 Genomic DNA Translation: ABC26118.1
DQ305583 Genomic DNA Translation: ABC26119.1
DQ305584 Genomic DNA Translation: ABC26120.1
DQ305585 Genomic DNA Translation: ABC26121.1
DQ305586 Genomic DNA Translation: ABC26122.1
DQ305587 Genomic DNA Translation: ABC26123.1
DQ305588 Genomic DNA Translation: ABC26124.1
DQ305589 Genomic DNA Translation: ABC26125.1
DQ305590 Genomic DNA Translation: ABC26126.1
DQ305591 Genomic DNA Translation: ABC26127.1
DQ305592 Genomic DNA Translation: ABC26128.1
DQ305593 Genomic DNA Translation: ABC26129.1
DQ305594 Genomic DNA Translation: ABC26130.1
DQ305595 Genomic DNA Translation: ABC26131.1
DQ305596 Genomic DNA Translation: ABC26132.1
DQ305597 Genomic DNA Translation: ABC26133.1
DQ305598 Genomic DNA Translation: ABC26134.1
DQ305599 Genomic DNA Translation: ABC26135.1
DQ305600 Genomic DNA Translation: ABC26136.1
DQ305601 Genomic DNA Translation: ABC26137.1
DQ305602 Genomic DNA Translation: ABC26138.1
DQ305603 Genomic DNA Translation: ABC26139.1
DQ305604 Genomic DNA Translation: ABC26140.1
DQ305605 Genomic DNA Translation: ABC26141.1
DQ305606 Genomic DNA Translation: ABC26142.1
DQ305607 Genomic DNA Translation: ABC26143.1
DQ305608 Genomic DNA Translation: ABC26144.1
DQ305609 Genomic DNA Translation: ABC26145.1
DQ305610 Genomic DNA Translation: ABC26146.1
DQ305611 Genomic DNA Translation: ABC26147.1
DQ305612 Genomic DNA Translation: ABC26148.1
DQ305613 Genomic DNA Translation: ABC26149.1
DQ305614 Genomic DNA Translation: ABC26150.1
DQ305615 Genomic DNA Translation: ABC26151.1
DQ305616 Genomic DNA Translation: ABC26152.1
DQ305617 Genomic DNA Translation: ABC26153.1
DQ305618 Genomic DNA Translation: ABC26154.1
DQ305619 Genomic DNA Translation: ABC26155.1
DQ305620 Genomic DNA Translation: ABC26156.1
DQ305621 Genomic DNA Translation: ABC26157.1
DQ305622 Genomic DNA Translation: ABC26158.1
DQ305623 Genomic DNA Translation: ABC26159.1
DQ305624 Genomic DNA Translation: ABC26160.1
DQ305625 Genomic DNA Translation: ABC26161.1
DQ305626 Genomic DNA Translation: ABC26162.1
DQ305627 Genomic DNA Translation: ABC26163.1
DQ305628 Genomic DNA Translation: ABC26164.1
DQ305629 Genomic DNA Translation: ABC26165.1
DQ305630 Genomic DNA Translation: ABC26166.1
DQ305631 Genomic DNA Translation: ABC26167.1
DQ305632 Genomic DNA Translation: ABC26168.1
DQ305633 Genomic DNA Translation: ABC26169.1
DQ305634 Genomic DNA Translation: ABC26170.1
DQ305635 Genomic DNA Translation: ABC26171.1
DQ305636 Genomic DNA Translation: ABC26172.1
DQ305637 Genomic DNA Translation: ABC26173.1
DQ305638 Genomic DNA Translation: ABC26174.1
DQ305639 Genomic DNA Translation: ABC26175.1
DQ305640 Genomic DNA Translation: ABC26176.1
DQ305641 Genomic DNA Translation: ABC26177.1
DQ305642 Genomic DNA Translation: ABC26178.1
DQ305643 Genomic DNA Translation: ABC26179.1
DQ305644 Genomic DNA Translation: ABC26180.1
DQ305645 Genomic DNA Translation: ABC26181.1
DQ305646 Genomic DNA Translation: ABC26182.1
DQ305647 Genomic DNA Translation: ABC26183.1
DQ305648 Genomic DNA Translation: ABC26184.1
DQ305649 Genomic DNA Translation: ABC26185.1
DQ305650 Genomic DNA Translation: ABC26186.1
DQ305651 Genomic DNA Translation: ABC26187.1
DQ305652 Genomic DNA Translation: ABC26188.1
DQ305653 Genomic DNA Translation: ABC26189.1
DQ305654 Genomic DNA Translation: ABC26190.1
DQ305655 Genomic DNA Translation: ABC26191.1
U53473 Genomic DNA Translation: AAA98976.1
AF042740 Genomic DNA Translation: AAC03773.1
AF055874 Genomic DNA Translation: AAC14117.1
AF055875 Genomic DNA Translation: AAC14118.1
AF320309 Genomic DNA Translation: AAG34181.1
AF348074 Genomic DNA Translation: AAK51710.1
AF348075 Genomic DNA Translation: AAK51711.1 Frameshift.
AY230251 Genomic DNA Translation: AAO73561.1
AY230252 Genomic DNA Translation: AAO73562.1
CR407631 mRNA Translation: CAG28559.1
AY331807 Genomic DNA Translation: AAP81164.1
AC025062 Genomic DNA No translation available.
AC120051 Genomic DNA No translation available.
BC015878 mRNA Translation: AAH15878.1
BC067218 mRNA Translation: AAH67218.1
M75163 Genomic DNA Translation: AAA59906.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6008.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B34585
S02788

NCBI Reference Sequences

More...
RefSeqi
NP_000006.2, NM_000015.2
XP_016868427.1, XM_017012938.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000286479; ENSP00000286479; ENSG00000156006

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10

UCSC genome browser

More...
UCSCi
uc003wyw.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology
NAT

NAT alleles

NIEHS-SNPs
SHMPD

The Singapore human mutation and polymorphism database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14672 Genomic DNA Translation: CAA32802.1
D90040 mRNA Translation: BAA14094.1
D90042 mRNA Translation: BAA14096.1
D10870 Genomic DNA Translation: BAA01640.1
D10871 Genomic DNA Translation: BAA01641.1
D10872 Genomic DNA Translation: BAA01642.1
U23052 Genomic DNA Translation: AAA64584.1
U23434 Genomic DNA Translation: AAA64585.1
DQ305496 Genomic DNA Translation: ABC26032.1
DQ305497 Genomic DNA Translation: ABC26033.1
DQ305498 Genomic DNA Translation: ABC26034.1
DQ305499 Genomic DNA Translation: ABC26035.1
DQ305500 Genomic DNA Translation: ABC26036.1
DQ305501 Genomic DNA Translation: ABC26037.1
DQ305502 Genomic DNA Translation: ABC26038.1
DQ305503 Genomic DNA Translation: ABC26039.1
DQ305504 Genomic DNA Translation: ABC26040.1
DQ305505 Genomic DNA Translation: ABC26041.1
DQ305506 Genomic DNA Translation: ABC26042.1
DQ305507 Genomic DNA Translation: ABC26043.1
DQ305508 Genomic DNA Translation: ABC26044.1
DQ305509 Genomic DNA Translation: ABC26045.1
DQ305510 Genomic DNA Translation: ABC26046.1
DQ305511 Genomic DNA Translation: ABC26047.1
DQ305512 Genomic DNA Translation: ABC26048.1
DQ305513 Genomic DNA Translation: ABC26049.1
DQ305514 Genomic DNA Translation: ABC26050.1
DQ305515 Genomic DNA Translation: ABC26051.1
DQ305516 Genomic DNA Translation: ABC26052.1
DQ305517 Genomic DNA Translation: ABC26053.1
DQ305518 Genomic DNA Translation: ABC26054.1
DQ305519 Genomic DNA Translation: ABC26055.1
DQ305520 Genomic DNA Translation: ABC26056.1
DQ305521 Genomic DNA Translation: ABC26057.1
DQ305522 Genomic DNA Translation: ABC26058.1
DQ305523 Genomic DNA Translation: ABC26059.1
DQ305524 Genomic DNA Translation: ABC26060.1
DQ305525 Genomic DNA Translation: ABC26061.1
DQ305526 Genomic DNA Translation: ABC26062.1
DQ305527 Genomic DNA Translation: ABC26063.1
DQ305528 Genomic DNA Translation: ABC26064.1
DQ305529 Genomic DNA Translation: ABC26065.1
DQ305530 Genomic DNA Translation: ABC26066.1
DQ305531 Genomic DNA Translation: ABC26067.1
DQ305532 Genomic DNA Translation: ABC26068.1
DQ305533 Genomic DNA Translation: ABC26069.1
DQ305534 Genomic DNA Translation: ABC26070.1
DQ305535 Genomic DNA Translation: ABC26071.1
DQ305536 Genomic DNA Translation: ABC26072.1
DQ305537 Genomic DNA Translation: ABC26073.1
DQ305538 Genomic DNA Translation: ABC26074.1
DQ305539 Genomic DNA Translation: ABC26075.1
DQ305540 Genomic DNA Translation: ABC26076.1
DQ305541 Genomic DNA Translation: ABC26077.1
DQ305542 Genomic DNA Translation: ABC26078.1
DQ305543 Genomic DNA Translation: ABC26079.1
DQ305544 Genomic DNA Translation: ABC26080.1
DQ305545 Genomic DNA Translation: ABC26081.1
DQ305546 Genomic DNA Translation: ABC26082.1
DQ305547 Genomic DNA Translation: ABC26083.1
DQ305548 Genomic DNA Translation: ABC26084.1
DQ305549 Genomic DNA Translation: ABC26085.1
DQ305550 Genomic DNA Translation: ABC26086.1
DQ305551 Genomic DNA Translation: ABC26087.1
DQ305552 Genomic DNA Translation: ABC26088.1
DQ305553 Genomic DNA Translation: ABC26089.1
DQ305554 Genomic DNA Translation: ABC26090.1
DQ305555 Genomic DNA Translation: ABC26091.1
DQ305556 Genomic DNA Translation: ABC26092.1
DQ305557 Genomic DNA Translation: ABC26093.1
DQ305558 Genomic DNA Translation: ABC26094.1
DQ305559 Genomic DNA Translation: ABC26095.1
DQ305560 Genomic DNA Translation: ABC26096.1
DQ305561 Genomic DNA Translation: ABC26097.1
DQ305562 Genomic DNA Translation: ABC26098.1
DQ305563 Genomic DNA Translation: ABC26099.1
DQ305564 Genomic DNA Translation: ABC26100.1
DQ305565 Genomic DNA Translation: ABC26101.1
DQ305566 Genomic DNA Translation: ABC26102.1
DQ305567 Genomic DNA Translation: ABC26103.1
DQ305568 Genomic DNA Translation: ABC26104.1
DQ305569 Genomic DNA Translation: ABC26105.1
DQ305570 Genomic DNA Translation: ABC26106.1
DQ305571 Genomic DNA Translation: ABC26107.1
DQ305572 Genomic DNA Translation: ABC26108.1
DQ305573 Genomic DNA Translation: ABC26109.1
DQ305574 Genomic DNA Translation: ABC26110.1
DQ305575 Genomic DNA Translation: ABC26111.1
DQ305576 Genomic DNA Translation: ABC26112.1
DQ305577 Genomic DNA Translation: ABC26113.1
DQ305578 Genomic DNA Translation: ABC26114.1
DQ305579 Genomic DNA Translation: ABC26115.1
DQ305580 Genomic DNA Translation: ABC26116.1
DQ305581 Genomic DNA Translation: ABC26117.1
DQ305582 Genomic DNA Translation: ABC26118.1
DQ305583 Genomic DNA Translation: ABC26119.1
DQ305584 Genomic DNA Translation: ABC26120.1
DQ305585 Genomic DNA Translation: ABC26121.1
DQ305586 Genomic DNA Translation: ABC26122.1
DQ305587 Genomic DNA Translation: ABC26123.1
DQ305588 Genomic DNA Translation: ABC26124.1
DQ305589 Genomic DNA Translation: ABC26125.1
DQ305590 Genomic DNA Translation: ABC26126.1
DQ305591 Genomic DNA Translation: ABC26127.1
DQ305592 Genomic DNA Translation: ABC26128.1
DQ305593 Genomic DNA Translation: ABC26129.1
DQ305594 Genomic DNA Translation: ABC26130.1
DQ305595 Genomic DNA Translation: ABC26131.1
DQ305596 Genomic DNA Translation: ABC26132.1
DQ305597 Genomic DNA Translation: ABC26133.1
DQ305598 Genomic DNA Translation: ABC26134.1
DQ305599 Genomic DNA Translation: ABC26135.1
DQ305600 Genomic DNA Translation: ABC26136.1
DQ305601 Genomic DNA Translation: ABC26137.1
DQ305602 Genomic DNA Translation: ABC26138.1
DQ305603 Genomic DNA Translation: ABC26139.1
DQ305604 Genomic DNA Translation: ABC26140.1
DQ305605 Genomic DNA Translation: ABC26141.1
DQ305606 Genomic DNA Translation: ABC26142.1
DQ305607 Genomic DNA Translation: ABC26143.1
DQ305608 Genomic DNA Translation: ABC26144.1
DQ305609 Genomic DNA Translation: ABC26145.1
DQ305610 Genomic DNA Translation: ABC26146.1
DQ305611 Genomic DNA Translation: ABC26147.1
DQ305612 Genomic DNA Translation: ABC26148.1
DQ305613 Genomic DNA Translation: ABC26149.1
DQ305614 Genomic DNA Translation: ABC26150.1
DQ305615 Genomic DNA Translation: ABC26151.1
DQ305616 Genomic DNA Translation: ABC26152.1
DQ305617 Genomic DNA Translation: ABC26153.1
DQ305618 Genomic DNA Translation: ABC26154.1
DQ305619 Genomic DNA Translation: ABC26155.1
DQ305620 Genomic DNA Translation: ABC26156.1
DQ305621 Genomic DNA Translation: ABC26157.1
DQ305622 Genomic DNA Translation: ABC26158.1
DQ305623 Genomic DNA Translation: ABC26159.1
DQ305624 Genomic DNA Translation: ABC26160.1
DQ305625 Genomic DNA Translation: ABC26161.1
DQ305626 Genomic DNA Translation: ABC26162.1
DQ305627 Genomic DNA Translation: ABC26163.1
DQ305628 Genomic DNA Translation: ABC26164.1
DQ305629 Genomic DNA Translation: ABC26165.1
DQ305630 Genomic DNA Translation: ABC26166.1
DQ305631 Genomic DNA Translation: ABC26167.1
DQ305632 Genomic DNA Translation: ABC26168.1
DQ305633 Genomic DNA Translation: ABC26169.1
DQ305634 Genomic DNA Translation: ABC26170.1
DQ305635 Genomic DNA Translation: ABC26171.1
DQ305636 Genomic DNA Translation: ABC26172.1
DQ305637 Genomic DNA Translation: ABC26173.1
DQ305638 Genomic DNA Translation: ABC26174.1
DQ305639 Genomic DNA Translation: ABC26175.1
DQ305640 Genomic DNA Translation: ABC26176.1
DQ305641 Genomic DNA Translation: ABC26177.1
DQ305642 Genomic DNA Translation: ABC26178.1
DQ305643 Genomic DNA Translation: ABC26179.1
DQ305644 Genomic DNA Translation: ABC26180.1
DQ305645 Genomic DNA Translation: ABC26181.1
DQ305646 Genomic DNA Translation: ABC26182.1
DQ305647 Genomic DNA Translation: ABC26183.1
DQ305648 Genomic DNA Translation: ABC26184.1
DQ305649 Genomic DNA Translation: ABC26185.1
DQ305650 Genomic DNA Translation: ABC26186.1
DQ305651 Genomic DNA Translation: ABC26187.1
DQ305652 Genomic DNA Translation: ABC26188.1
DQ305653 Genomic DNA Translation: ABC26189.1
DQ305654 Genomic DNA Translation: ABC26190.1
DQ305655 Genomic DNA Translation: ABC26191.1
U53473 Genomic DNA Translation: AAA98976.1
AF042740 Genomic DNA Translation: AAC03773.1
AF055874 Genomic DNA Translation: AAC14117.1
AF055875 Genomic DNA Translation: AAC14118.1
AF320309 Genomic DNA Translation: AAG34181.1
AF348074 Genomic DNA Translation: AAK51710.1
AF348075 Genomic DNA Translation: AAK51711.1 Frameshift.
AY230251 Genomic DNA Translation: AAO73561.1
AY230252 Genomic DNA Translation: AAO73562.1
CR407631 mRNA Translation: CAG28559.1
AY331807 Genomic DNA Translation: AAP81164.1
AC025062 Genomic DNA No translation available.
AC120051 Genomic DNA No translation available.
BC015878 mRNA Translation: AAH15878.1
BC067218 mRNA Translation: AAH67218.1
M75163 Genomic DNA Translation: AAA59906.1
CCDSiCCDS6008.1
PIRiB34585
S02788
RefSeqiNP_000006.2, NM_000015.2
XP_016868427.1, XM_017012938.1
UniGeneiHs.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PFRX-ray1.92A/B2-290[»]
ProteinModelPortaliP11245
SMRiP11245
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi106528, 20 interactors
IntActiP11245, 19 interactors
MINTiP11245
STRINGi9606.ENSP00000286479

Chemistry databases

ChEMBLiCHEMBL2194
DrugBankiDB00316 Acetaminophen
DB01068 Clonazepam
DB00250 Dapsone
DB04953 Ezogabine
DB00951 Isoniazid
DB01015 Sulfamethoxazole

PTM databases

iPTMnetiP11245
PhosphoSitePlusiP11245

Polymorphism and mutation databases

BioMutaiNAT2
DMDMi114238

Proteomic databases

MaxQBiP11245
PaxDbiP11245
PeptideAtlasiP11245
PRIDEiP11245
ProteomicsDBi52728

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000286479; ENSP00000286479; ENSG00000156006
GeneIDi10
KEGGihsa:10
UCSCiuc003wyw.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10
DisGeNETi10
EuPathDBiHostDB:ENSG00000156006.4

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NAT2
HGNCiHGNC:7646 NAT2
HPAiHPA043704
MalaCardsiNAT2
MIMi243400 phenotype
612182 gene
neXtProtiNX_P11245
Orphaneti240887 Isoniazid toxicity
PharmGKBiPA18

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IFD6 Eukaryota
COG2162 LUCA
HOVERGENiHBG000165
InParanoidiP11245
KOiK00622
OrthoDBi1545569at2759
PhylomeDBiP11245
TreeFamiTF106311

Enzyme and pathway databases

BRENDAi2.3.1.5 2681
ReactomeiR-HSA-156582 Acetylation

Miscellaneous databases

EvolutionaryTraceiP11245

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
N-acetyltransferase_2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10

Protein Ontology

More...
PROi
PR:P11245

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000156006 Expressed in 83 organ(s), highest expression level in liver
CleanExiHS_NAT2
ExpressionAtlasiP11245 baseline and differential
GenevisibleiP11245 HS

Family and domain databases

InterProiView protein in InterPro
IPR001447 Arylamine_N-AcTrfase
IPR038765 Papain_like_cys_pep_sf
PANTHERiPTHR11786 PTHR11786, 1 hit
PfamiView protein in Pfam
PF00797 Acetyltransf_2, 1 hit
PRINTSiPR01543 ANATRNSFRASE
SUPFAMiSSF54001 SSF54001, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARY2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P11245
Secondary accession number(s): O43637
, O60654, O60655, Q13146, Q16697, Q2MLE4, Q2MLF5, Q2MLG8, Q2MLJ6, Q2MLK4, Q2MLK6, Q2MLN7, Q6LET4, Q86XS0, Q86XS1, Q96KY8, Q96T64, Q96T65, Q9H220
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: January 16, 2019
This is version 173 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
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