UniProtKB - P11229 (ACM1_HUMAN)
Muscarinic acetylcholine receptor M1
CHRM1
Functioni
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 170 | Subtype-specific residue that binds to snake venom muscarinic toxin 71 Publication | 1 | |
Sitei | 172 | Binds to snake venom muscarinic toxin 71 Publication | 1 | |
Sitei | 174 | Subtype-specific residue that binds to snake venom muscarinic toxin 71 Publication | 1 | |
Sitei | 397 | Subtype-specific residue that binds to snake venom muscarinic toxin 71 Publication | 1 | |
Sitei | 401 | Subtype-specific residue that binds to snake venom muscarinic toxin 71 Publication | 1 |
GO - Molecular functioni
- G protein-coupled acetylcholine receptor activity Source: GO_Central
- G protein-coupled serotonin receptor activity Source: GO_Central
- neurotransmitter receptor activity Source: GO_Central
- neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Source: Ensembl
- phosphatidylinositol phospholipase C activity Source: ProtInc
GO - Biological processi
- adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway Source: GO_Central
- chemical synaptic transmission Source: GO_Central
- cognition Source: InterPro
- G protein-coupled acetylcholine receptor signaling pathway Source: ProtInc
- G protein-coupled receptor signaling pathway Source: ProtInc
- G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Source: GO_Central
- nervous system development Source: ProtInc
- neuromuscular synaptic transmission Source: Ensembl
- phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway Source: ProtInc
- positive regulation of intracellular protein transport Source: Ensembl
- positive regulation of ion transport Source: MGI
- protein kinase C-activating G protein-coupled receptor signaling pathway Source: ProtInc
- regulation of glial cell proliferation Source: GO_Central
- regulation of locomotion Source: Ensembl
- saliva secretion Source: InterPro
- signal transduction Source: GO_Central
Keywordsi
Molecular function | G-protein coupled receptor, Receptor, Transducer |
Enzyme and pathway databases
PathwayCommonsi | P11229 |
Reactomei | R-HSA-390648, Muscarinic acetylcholine receptors R-HSA-416476, G alpha (q) signalling events |
SignaLinki | P11229 |
SIGNORi | P11229 |
Names & Taxonomyi
Protein namesi | Recommended name: Muscarinic acetylcholine receptor M1 |
Gene namesi | Name:CHRM1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:1950, CHRM1 |
MIMi | 118510, gene |
neXtProti | NX_P11229 |
VEuPathDBi | HostDB:ENSG00000168539 |
Subcellular locationi
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
- integral component of postsynaptic density membrane Source: Ensembl
- integral component of presynaptic membrane Source: Ensembl
- plasma membrane Source: Reactome
Other locations
- axon terminus Source: Ensembl
- cholinergic synapse Source: Ensembl
- dendrite Source: GO_Central
- glutamatergic synapse Source: Ensembl
- membrane Source: ProtInc
- Schaffer collateral - CA1 synapse Source: Ensembl
- synapse Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 22 | ExtracellularCombined sources1 PublicationAdd BLAST | 22 | |
Transmembranei | 23 – 48 | Helical; Name=1Combined sources1 PublicationAdd BLAST | 26 | |
Topological domaini | 49 – 62 | CytoplasmicCombined sources1 PublicationAdd BLAST | 14 | |
Transmembranei | 63 – 84 | Helical; Name=2Combined sources1 PublicationAdd BLAST | 22 | |
Topological domaini | 85 – 95 | ExtracellularCombined sources1 PublicationAdd BLAST | 11 | |
Transmembranei | 96 – 121 | Helical; Name=3Combined sources1 PublicationAdd BLAST | 26 | |
Topological domaini | 122 – 142 | CytoplasmicCombined sources1 PublicationAdd BLAST | 21 | |
Transmembranei | 143 – 164 | Helical; Name=4Combined sources1 PublicationAdd BLAST | 22 | |
Topological domaini | 165 – 185 | ExtracellularCombined sources1 PublicationAdd BLAST | 21 | |
Transmembranei | 186 – 209 | Helical; Name=5Combined sources1 PublicationAdd BLAST | 24 | |
Topological domaini | 210 – 366 | CytoplasmicCombined sources1 PublicationAdd BLAST | 157 | |
Transmembranei | 367 – 390 | Helical; Name=6Combined sources1 PublicationAdd BLAST | 24 | |
Topological domaini | 391 – 397 | ExtracellularCombined sources1 Publication | 7 | |
Transmembranei | 398 – 420 | Helical; Name=7Combined sources1 PublicationAdd BLAST | 23 | |
Topological domaini | 421 – 460 | CytoplasmicCombined sources1 PublicationAdd BLAST | 40 |
Keywords - Cellular componenti
Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, SynapsePathology & Biotechi
Organism-specific databases
DisGeNETi | 1128 |
OpenTargetsi | ENSG00000168539 |
PharmGKBi | PA26484 |
Miscellaneous databases
Pharosi | P11229, Tclin |
Chemistry databases
ChEMBLi | CHEMBL216 |
DrugBanki | DB03128, Acetylcholine DB08897, Aclidinium DB05766, ACP-104 DB05752, ALKS 27 DB00321, Amitriptyline DB00543, Amoxapine DB00517, Anisotropine methylbromide DB04365, Arecoline DB01238, Aripiprazole DB14185, Aripiprazole lauroxil DB00572, Atropine DB00245, Benzatropine DB00767, Benzquinamide DB01019, Bethanechol DB00810, Biperiden DB00835, Brompheniramine DB00354, Buclizine DB00411, Carbamoylcholine DB00185, Cevimeline DB00477, Chlorpromazine DB01239, Chlorprothixene DB00568, Cinnarizine DB00771, Clidinium DB00363, Clozapine DB00907, Cocaine DB00979, Cyclopentolate DB00942, Cycrimine DB00434, Cyproheptadine DB00496, Darifenacin DB01151, Desipramine DB00804, Dicyclomine DB01231, Diphenidol DB00280, Disopyramide DB09167, Dosulepin DB01142, Doxepin DB00366, Doxylamine DB01175, Escitalopram DB09194, Etoperidone DB06702, Fesoterodine DB01148, Flavoxate DB00875, Flupentixol DB00483, Gallamine triethiodide DB00986, Glycopyrronium DB06787, Hexocyclium DB11181, Homatropine DB00725, Homatropine methylbromide DB00424, Hyoscyamine DB09262, Imidafenacin DB00458, Imipramine DB00332, Ipratropium DB01221, Ketamine DB00408, Loxapine DB00934, Maprotiline DB04843, Mepenzolate DB00454, Meperidine DB06709, Methacholine DB00940, Methantheline DB01403, Methotrimeprazine DB00462, Methscopolamine bromide DB00340, Metixene DB01233, Metoclopramide DB00805, Minaprine DB01618, Molindone DB05152, NGX267 DB00622, Nicardipine DB00540, Nortriptyline DB00334, Olanzapine DB01062, Oxybutynin DB00383, Oxyphencyclimine DB00219, Oxyphenonium DB00715, Paroxetine DB01085, Pilocarpine DB00670, Pirenzepine DB06153, Pizotifen DB00387, Procyclidine DB00392, Profenamine DB00420, Promazine DB01069, Promethazine DB00782, Propantheline DB00777, Propiomazine DB12278, Propiverine DB11156, Pyrantel DB01224, Quetiapine DB11855, Revefenacin DB13581, Rociverine DB00747, Scopolamine DB01591, Solifenacin DB02010, Staurosporine DB00342, Terfenadine DB11235, Thonzylamine DB01409, Tiotropium DB01036, Tolterodine DB00193, Tramadol DB00505, Tridihexethyl DB00508, Triflupromazine DB00376, Trihexyphenidyl DB09089, Trimebutine DB00726, Trimipramine DB00809, Tropicamide DB00209, Trospium DB09076, Umeclidinium DB00246, Ziprasidone |
DrugCentrali | P11229 |
GuidetoPHARMACOLOGYi | 13 |
Genetic variation databases
BioMutai | CHRM1 |
DMDMi | 113118 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000069015 | 1 – 460 | Muscarinic acetylcholine receptor M1Add BLAST | 460 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 2 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 12 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Disulfide bondi | 98 ↔ 178 | PROSITE-ProRule annotation | ||
Modified residuei | 230 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 428 | PhosphothreonineSequence analysis | 1 | |
Modified residuei | 451 | PhosphoserineSequence analysis | 1 | |
Modified residuei | 455 | PhosphothreonineSequence analysis | 1 | |
Modified residuei | 457 | PhosphoserineSequence analysis | 1 |
Keywords - PTMi
Disulfide bond, Glycoprotein, PhosphoproteinProteomic databases
MassIVEi | P11229 |
PaxDbi | P11229 |
PeptideAtlasi | P11229 |
PRIDEi | P11229 |
ProteomicsDBi | 52724 [P11229-1] 77961 |
PTM databases
GlyGeni | P11229, 2 sites |
iPTMneti | P11229 |
PhosphoSitePlusi | P11229 |
Expressioni
Gene expression databases
Bgeei | ENSG00000168539, Expressed in anterior cingulate cortex and 100 other tissues |
ExpressionAtlasi | P11229, baseline and differential |
Genevisiblei | P11229, HS |
Organism-specific databases
HPAi | ENSG00000168539, Group enriched (brain, prostate, salivary gland) |
Interactioni
Subunit structurei
Protein-protein interaction databases
BioGRIDi | 107550, 4 interactors |
IntActi | P11229, 5 interactors |
MINTi | P11229 |
STRINGi | 9606.ENSP00000306490 |
Chemistry databases
BindingDBi | P11229 |
Miscellaneous databases
RNActi | P11229, protein |
Structurei
Secondary structure
3D structure databases
AlphaFoldDBi | P11229 |
SMRi | P11229 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 225 – 256 | DisorderedSequence analysisAdd BLAST | 32 | |
Regioni | 274 – 297 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 310 – 351 | DisorderedSequence analysisAdd BLAST | 42 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 231 – 248 | Polar residuesSequence analysisAdd BLAST | 18 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG4220, Eukaryota |
GeneTreei | ENSGT00940000162301 |
HOGENOMi | CLU_009579_11_2_1 |
InParanoidi | P11229 |
OMAi | RCCRTPR |
PhylomeDBi | P11229 |
TreeFami | TF320495 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR002228, Musac_Ach_M1_rcpt IPR000995, Musac_Ach_rcpt |
PANTHERi | PTHR24248:SF155, PTHR24248:SF155, 1 hit |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN PR00243, MUSCARINICR PR00538, MUSCRINICM1R |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MNTSAPPAVS PNITVLAPGK GPWQVAFIGI TTGLLSLATV TGNLLVLISF
60 70 80 90 100
KVNTELKTVN NYFLLSLACA DLIIGTFSMN LYTTYLLMGH WALGTLACDL
110 120 130 140 150
WLALDYVASN ASVMNLLLIS FDRYFSVTRP LSYRAKRTPR RAALMIGLAW
160 170 180 190 200
LVSFVLWAPA ILFWQYLVGE RTVLAGQCYI QFLSQPIITF GTAMAAFYLP
210 220 230 240 250
VTVMCTLYWR IYRETENRAR ELAALQGSET PGKGGGSSSS SERSQPGAEG
260 270 280 290 300
SPETPPGRCC RCCRAPRLLQ AYSWKEEEEE DEGSMESLTS SEGEEPGSEV
310 320 330 340 350
VIKMPMVDPE AQAPTKQPPR SSPNTVKRPT KKGRDRAGKG QKPRGKEQLA
360 370 380 390 400
KRKTFSLVKE KKAARTLSAI LLAFILTWTP YNIMVLVSTF CKDCVPETLW
410 420 430 440 450
ELGYWLCYVN STINPMCYAL CNKAFRDTFR LLLLCRWDKR RWRKIPKRPG
460
SVHRTPSRQC
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF5GZF8 | F5GZF8_HUMAN | Muscarinic acetylcholine receptor | CHRM1 | 134 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 173 | V → M in CAA33334 (PubMed:3443095).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_056651 | 455 – 460 | Missing in isoform 2. 1 Publication | 6 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y00508 Genomic DNA Translation: CAA68560.1 X52068 Genomic DNA Translation: CAA36291.1 X15263 Genomic DNA Translation: CAA33334.1 AF385587 mRNA Translation: AAK68112.1 AF498915 mRNA Translation: AAM18938.1 AP000438 Genomic DNA No translation available. BC007740 mRNA Translation: AAH07740.1 BC022984 mRNA Translation: AAH22984.1 |
CCDSi | CCDS8040.1 [P11229-1] |
PIRi | S09508 |
RefSeqi | NP_000729.2, NM_000738.2 [P11229-1] XP_011543044.1, XM_011544742.2 [P11229-1] |
Genome annotation databases
Ensembli | ENST00000306960.4; ENSP00000306490.3; ENSG00000168539.4 ENST00000543973.1; ENSP00000441188.1; ENSG00000168539.4 [P11229-2] |
GeneIDi | 1128 |
KEGGi | hsa:1128 |
MANE-Selecti | ENST00000306960.4; ENSP00000306490.3; NM_000738.3; NP_000729.2 |
UCSCi | uc058cqg.1, human [P11229-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y00508 Genomic DNA Translation: CAA68560.1 X52068 Genomic DNA Translation: CAA36291.1 X15263 Genomic DNA Translation: CAA33334.1 AF385587 mRNA Translation: AAK68112.1 AF498915 mRNA Translation: AAM18938.1 AP000438 Genomic DNA No translation available. BC007740 mRNA Translation: AAH07740.1 BC022984 mRNA Translation: AAH22984.1 |
CCDSi | CCDS8040.1 [P11229-1] |
PIRi | S09508 |
RefSeqi | NP_000729.2, NM_000738.2 [P11229-1] XP_011543044.1, XM_011544742.2 [P11229-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5CXV | X-ray | 2.70 | A | 2-218 | [»] | |
A | 355-460 | [»] | ||||
6OIJ | electron microscopy | 3.30 | R | 2-460 | [»] | |
6WJC | X-ray | 2.55 | A | 2-218 | [»] | |
A | 355-460 | [»] | ||||
6ZFZ | X-ray | 2.17 | A | 27-219 | [»] | |
A | 355-438 | [»] | ||||
6ZG4 | X-ray | 2.33 | A | 27-219 | [»] | |
A | 355-438 | [»] | ||||
6ZG9 | X-ray | 2.50 | A | 27-219 | [»] | |
A | 355-438 | [»] | ||||
AlphaFoldDBi | P11229 | |||||
SMRi | P11229 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 107550, 4 interactors |
IntActi | P11229, 5 interactors |
MINTi | P11229 |
STRINGi | 9606.ENSP00000306490 |
Chemistry databases
BindingDBi | P11229 |
ChEMBLi | CHEMBL216 |
DrugBanki | DB03128, Acetylcholine DB08897, Aclidinium DB05766, ACP-104 DB05752, ALKS 27 DB00321, Amitriptyline DB00543, Amoxapine DB00517, Anisotropine methylbromide DB04365, Arecoline DB01238, Aripiprazole DB14185, Aripiprazole lauroxil DB00572, Atropine DB00245, Benzatropine DB00767, Benzquinamide DB01019, Bethanechol DB00810, Biperiden DB00835, Brompheniramine DB00354, Buclizine DB00411, Carbamoylcholine DB00185, Cevimeline DB00477, Chlorpromazine DB01239, Chlorprothixene DB00568, Cinnarizine DB00771, Clidinium DB00363, Clozapine DB00907, Cocaine DB00979, Cyclopentolate DB00942, Cycrimine DB00434, Cyproheptadine DB00496, Darifenacin DB01151, Desipramine DB00804, Dicyclomine DB01231, Diphenidol DB00280, Disopyramide DB09167, Dosulepin DB01142, Doxepin DB00366, Doxylamine DB01175, Escitalopram DB09194, Etoperidone DB06702, Fesoterodine DB01148, Flavoxate DB00875, Flupentixol DB00483, Gallamine triethiodide DB00986, Glycopyrronium DB06787, Hexocyclium DB11181, Homatropine DB00725, Homatropine methylbromide DB00424, Hyoscyamine DB09262, Imidafenacin DB00458, Imipramine DB00332, Ipratropium DB01221, Ketamine DB00408, Loxapine DB00934, Maprotiline DB04843, Mepenzolate DB00454, Meperidine DB06709, Methacholine DB00940, Methantheline DB01403, Methotrimeprazine DB00462, Methscopolamine bromide DB00340, Metixene DB01233, Metoclopramide DB00805, Minaprine DB01618, Molindone DB05152, NGX267 DB00622, Nicardipine DB00540, Nortriptyline DB00334, Olanzapine DB01062, Oxybutynin DB00383, Oxyphencyclimine DB00219, Oxyphenonium DB00715, Paroxetine DB01085, Pilocarpine DB00670, Pirenzepine DB06153, Pizotifen DB00387, Procyclidine DB00392, Profenamine DB00420, Promazine DB01069, Promethazine DB00782, Propantheline DB00777, Propiomazine DB12278, Propiverine DB11156, Pyrantel DB01224, Quetiapine DB11855, Revefenacin DB13581, Rociverine DB00747, Scopolamine DB01591, Solifenacin DB02010, Staurosporine DB00342, Terfenadine DB11235, Thonzylamine DB01409, Tiotropium DB01036, Tolterodine DB00193, Tramadol DB00505, Tridihexethyl DB00508, Triflupromazine DB00376, Trihexyphenidyl DB09089, Trimebutine DB00726, Trimipramine DB00809, Tropicamide DB00209, Trospium DB09076, Umeclidinium DB00246, Ziprasidone |
DrugCentrali | P11229 |
GuidetoPHARMACOLOGYi | 13 |
Protein family/group databases
GPCRDBi | Search... |
PTM databases
GlyGeni | P11229, 2 sites |
iPTMneti | P11229 |
PhosphoSitePlusi | P11229 |
Genetic variation databases
BioMutai | CHRM1 |
DMDMi | 113118 |
Proteomic databases
MassIVEi | P11229 |
PaxDbi | P11229 |
PeptideAtlasi | P11229 |
PRIDEi | P11229 |
ProteomicsDBi | 52724 [P11229-1] 77961 |
Protocols and materials databases
ABCDi | P11229, 12 sequenced antibodies |
Antibodypediai | 2948, 325 antibodies from 37 providers |
DNASUi | 1128 |
Genome annotation databases
Ensembli | ENST00000306960.4; ENSP00000306490.3; ENSG00000168539.4 ENST00000543973.1; ENSP00000441188.1; ENSG00000168539.4 [P11229-2] |
GeneIDi | 1128 |
KEGGi | hsa:1128 |
MANE-Selecti | ENST00000306960.4; ENSP00000306490.3; NM_000738.3; NP_000729.2 |
UCSCi | uc058cqg.1, human [P11229-1] |
Organism-specific databases
CTDi | 1128 |
DisGeNETi | 1128 |
GeneCardsi | CHRM1 |
HGNCi | HGNC:1950, CHRM1 |
HPAi | ENSG00000168539, Group enriched (brain, prostate, salivary gland) |
MIMi | 118510, gene |
neXtProti | NX_P11229 |
OpenTargetsi | ENSG00000168539 |
PharmGKBi | PA26484 |
VEuPathDBi | HostDB:ENSG00000168539 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG4220, Eukaryota |
GeneTreei | ENSGT00940000162301 |
HOGENOMi | CLU_009579_11_2_1 |
InParanoidi | P11229 |
OMAi | RCCRTPR |
PhylomeDBi | P11229 |
TreeFami | TF320495 |
Enzyme and pathway databases
PathwayCommonsi | P11229 |
Reactomei | R-HSA-390648, Muscarinic acetylcholine receptors R-HSA-416476, G alpha (q) signalling events |
SignaLinki | P11229 |
SIGNORi | P11229 |
Miscellaneous databases
BioGRID-ORCSi | 1128, 15 hits in 1073 CRISPR screens |
ChiTaRSi | CHRM1, human |
GeneWikii | Muscarinic_acetylcholine_receptor_M1 |
GenomeRNAii | 1128 |
Pharosi | P11229, Tclin |
PROi | PR:P11229 |
RNActi | P11229, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000168539, Expressed in anterior cingulate cortex and 100 other tissues |
ExpressionAtlasi | P11229, baseline and differential |
Genevisiblei | P11229, HS |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR002228, Musac_Ach_M1_rcpt IPR000995, Musac_Ach_rcpt |
PANTHERi | PTHR24248:SF155, PTHR24248:SF155, 1 hit |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN PR00243, MUSCARINICR PR00538, MUSCRINICM1R |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ACM1_HUMAN | |
Accessioni | P11229Primary (citable) accession number: P11229 Secondary accession number(s): Q96RH1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1989 |
Last sequence update: | November 1, 1990 | |
Last modified: | May 25, 2022 | |
This is version 214 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- 7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries - Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families