Plat

Functionⁱ

Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events.

Catalytic activityⁱ

Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.

Activity regulationⁱ

Inhibited by SERPINA5.By similarity

Sites

Feature key	Position(s)	DescriptionActions	Length
Siteⁱ	99	Important for binding to LRP1By similarity	1
Active siteⁱ	355	Charge relay system	1
Active siteⁱ	404	Charge relay system	1
Siteⁱ	462	Important for single-chain activityBy similarity	1
Siteⁱ	509	Important for single-chain activityBy similarity	1
Active siteⁱ	510	Charge relay system	1

GO - Molecular functionⁱ

phosphoprotein binding Source: MGI
serine-type endopeptidase activity
Source: MGI
Inferred from direct assayⁱ
- 15372073
signaling receptor binding Source: MGI

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of proteolysis Source: MGI
plasminogen activation Source: MGI
platelet-derived growth factor receptor signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 15372073
positive regulation of ovulation Source: MGI
proteolysis
Source: MGI
Inferred from direct assayⁱ
- 15372073
response to hypoxia
Source: MGI
Inferred from mutant phenotypeⁱ
- 17382917
smooth muscle cell migration
Source: MGI
Inferred from mutant phenotypeⁱ
- 17382917
synaptic transmission, glutamatergic Source: MGI
trans-synaptic signaling by BDNF, modulating synaptic transmission
Source: SynGO
Inferred from mutant phenotypeⁱ
- 15486301

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Hydrolase, Protease, Serine protease
Biological process	Plasminogen activation

Enzyme and pathway databases

BRENDAⁱ	3.4.21.68 3474
Reactomeⁱ	R-MMU-186797 Signaling by PDGF R-MMU-75205 Dissolution of Fibrin Clot

Protein family/group databases

MEROPS protease database More...MEROPSⁱ	S01.232

MEROPSⁱ

S01.232

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Tissue-type plasminogen activator (EC:3.4.21.68) Short name: t-PA Short name: t-plasminogen activator Short name: tPA Cleaved into the following 2 chains: Tissue-type plasminogen activator chain A Tissue-type plasminogen activator chain B
Gene namesⁱ	Name:Plat
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 8

Organism-specific databases

MGIⁱ	MGI:97610 Plat

Keywords - Cellular componentⁱ

Secreted

Pathology & Biotechⁱ

Chemistry databases

ChEMBLⁱ	CHEMBL3259492

ChEMBLⁱ

CHEMBL3259492

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Length
Signal peptideⁱ	1 – 17	Sequence analysisAdd BLAST	17
PropeptideⁱPRO_0000028353	18 – 29	By similarityAdd BLAST	12
PropeptideⁱPRO_0000285906	30 – 32	Removed by plasmin1 Publication	3
ChainⁱPRO_0000028354	33 – 559	Tissue-type plasminogen activatorAdd BLAST	527
ChainⁱPRO_0000028355	33 – 308	Tissue-type plasminogen activator chain AAdd BLAST	276
ChainⁱPRO_0000028356	309 – 559	Tissue-type plasminogen activator chain BAdd BLAST	251

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Disulfide bondⁱ	38 ↔ 68	By similarity
Disulfide bondⁱ	66 ↔ 75	By similarity
Disulfide bondⁱ	83 ↔ 94	By similarity
Disulfide bondⁱ	88 ↔ 105	By similarity
Disulfide bondⁱ	107 ↔ 116	By similarity
Disulfide bondⁱ	124 ↔ 205	By similarity
Disulfide bondⁱ	145 ↔ 187	By similarity
Glycosylationⁱ	149	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	176 ↔ 200	By similarity
Disulfide bondⁱ	213 ↔ 294	By similarity
Disulfide bondⁱ	234 ↔ 276	By similarity
Disulfide bondⁱ	265 ↔ 289	By similarity
Disulfide bondⁱ	297 ↔ 428	Interchain (between A and B chains)PROSITE-ProRule annotation
Disulfide bondⁱ	340 ↔ 356	By similarity
Disulfide bondⁱ	348 ↔ 417	By similarity
Disulfide bondⁱ	442 ↔ 516	By similarity
Disulfide bondⁱ	474 ↔ 490	By similarity
Glycosylationⁱ	481	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	506 ↔ 534	By similarity

Post-translational modificationⁱ

The single chain, almost fully active enzyme, can be further processed into a two-chain fully active form by a cleavage after Arg-308 catalyzed by plasmin, tissue kallikrein or factor Xa.

Keywords - PTMⁱ

Cleavage on pair of basic residues, Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P11214
PaxDbⁱ	P11214
PeptideAtlas More...PeptideAtlasⁱ	P11214
PRIDEⁱ	P11214

PTM databases

iPTMnetⁱ	P11214
PhosphoSitePlusⁱ	P11214

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000031538 Expressed in 287 organ(s), highest expression level in primary oocyte
CleanExⁱ	MM_PLAT
Genevisibleⁱ	P11214 MM

Interactionⁱ

Subunit structureⁱ

Heterodimer of chain A and chain B held by a disulfide bond. Binds to fibrin with high affinity. This interaction leads to an increase in the catalytic efficiency of the enzyme due to an increase in affinity for plasminogen. Similarly, binding to heparin increases the activation of plasminogen. Binds to annexin A2, cytokeratin-8, fibronectin and laminin. Binds to mannose receptor and the low-density lipoprotein receptor-related protein (LRP1); these proteins are involved in TPA clearance. Binds LRP1B; binding is followed by internalization and degradation. Forms heterodimer with SERPINA5 (By similarity).By similarity

GO - Molecular functionⁱ

phosphoprotein binding Source: MGI
signaling receptor binding Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

ComplexPortalⁱ	CPX-518 tPA-PAI-1 complex
IntActⁱ	P11214, 2 interactors
Molecular INTeraction database More...MINTⁱ	P11214
STRINGⁱ	10090.ENSMUSP00000033941

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P11214
SMRⁱ	P11214
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	36 – 78	Fibronectin type-IPROSITE-ProRule annotationAdd BLAST	43
Domainⁱ	79 – 117	EGF-likePROSITE-ProRule annotationAdd BLAST	39
Domainⁱ	124 – 205	Kringle 1PROSITE-ProRule annotationAdd BLAST	82
Domainⁱ	213 – 294	Kringle 2PROSITE-ProRule annotationAdd BLAST	82
Domainⁱ	309 – 558	Peptidase S1PROSITE-ProRule annotationAdd BLAST	250

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	39 – 49	Important for binding to annexin A2By similarityAdd BLAST		11

Domainⁱ

Both FN1 and one of the kringle domains are required for binding to fibrin.By similarity

Both FN1 and EGF-like domains are important for binding to LRP1.By similarity

The FN1 domain mediates binding to annexin A2.By similarity

The second kringle domain is implicated in binding to cytokeratin-8 and to the endothelial cell surface binding site.By similarity

Sequence similaritiesⁱ

Belongs to the peptidase S1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

EGF-like domain, Kringle, Repeat, Signal

Phylogenomic databases

eggNOGⁱ	KOG3627 Eukaryota COG5640 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119133
HOGENOMⁱ	HOG000237314
HOVERGENⁱ	HBG008633
InParanoidⁱ	P11214
KEGG Orthology (KO) More...KOⁱ	K01343
OMAⁱ	PLVCMKD
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AH5
PhylomeDBⁱ	P11214
TreeFamⁱ	TF329901

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00061 FN1, 1 hit cd00108 KR, 2 hits cd00190 Tryp_SPc, 1 hit
Gene3Dⁱ	2.40.20.10, 2 hits
InterProⁱ	View protein in InterPro IPR013032 EGF-like_CS IPR000742 EGF-like_dom IPR000083 Fibronectin_type1 IPR000001 Kringle IPR013806 Kringle-like IPR018056 Kringle_CS IPR038178 Kringle_sf IPR009003 Peptidase_S1_PA IPR001314 Peptidase_S1A IPR026280 Tissue_plasm_act IPR034811 tPA IPR001254 Trypsin_dom IPR018114 TRYPSIN_HIS IPR033116 TRYPSIN_SER
PANTHERⁱ	PTHR44617 PTHR44617, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00008 EGF, 1 hit PF00039 fn1, 1 hit PF00051 Kringle, 2 hits PF00089 Trypsin, 1 hit
PIRSFⁱ	PIRSF001145 Tissue_plasm_act, 1 hit
PRINTSⁱ	PR00722 CHYMOTRYPSIN
SMARTⁱ	View protein in SMART SM00181 EGF, 1 hit SM00058 FN1, 1 hit SM00130 KR, 2 hits SM00020 Tryp_SPc, 1 hit
SUPFAMⁱ	SSF50494 SSF50494, 1 hit SSF57440 SSF57440, 2 hits
PROSITEⁱ	View protein in PROSITE PS00022 EGF_1, 1 hit PS01186 EGF_2, 1 hit PS50026 EGF_3, 1 hit PS01253 FN1_1, 1 hit PS51091 FN1_2, 1 hit PS00021 KRINGLE_1, 2 hits PS50070 KRINGLE_2, 2 hits PS50240 TRYPSIN_DOM, 1 hit PS00134 TRYPSIN_HIS, 1 hit PS00135 TRYPSIN_SER, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P11214-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKRELLCVLL LCGLAFPLPD QGIHGRFRRG ARSYRATCRD EPTQTTYQQH 
        60         70         80         90        100
QSWLRPMLRS SRVEYCRCNS GLVQCHSVPV RSCSEPRCFN GGTCQQALYF 
       110        120        130        140        150
SDFVCQCPDG FVGKRCDIDT RATCFEEQGI TYRGTWSTAE SGAECINWNS 
       160        170        180        190        200
SVLSLKPYNA RRPNAIKLGL GNHNYCRNPD RDLKPWCYVF KAGKYTTEFC 
       210        220        230        240        250
STPACPKGKS EDCYVGKGVT YRGTHSLTTS QASCLPWNSI VLMGKSYTAW 
       260        270        280        290        300
RTNSQALGLG RHNYCRNPDG DARPWCHVMK DRKLTWEYCD MSPCSTCGLR 
       310        320        330        340        350
QYKRPQFRIK GGLYTDITSH PWQAAIFVKN KRSPGERFLC GGVLISSCWV 
       360        370        380        390        400
LSAAHCFLER FPPNHLKVVL GRTYRVVPGE EEQTFEIEKY IVHEEFDDDT 
       410        420        430        440        450
YDNDIALLQL RSQSKQCAQE SSSVGTACLP DPNLQLPDWT ECELSGYGKH 
       460        470        480        490        500
EASSPFFSDR LKEAHVRLYP SSRCTSQHLF NKTVTNNMLC AGDTRSGGNQ 
       510        520        530        540        550
DLHDACQGDS GGPLVCMINK QMTLTGIISW GLGCGQKDVP GVYTKVTNYL 

DWIHDNMKQ

Length:559

Mass (Da):63,097

Last modified:October 2, 2007 - v3

Checksum:ⁱ0A158A5A273CFAA0

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	260	G → A in AAA40470 (PubMed:2826484).Curated		1
Sequence conflictⁱ	325	A → P in AAH11256 (PubMed:15489334).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	J03520 mRNA Translation: AAA40470.1 AK135857 mRNA Translation: BAE22698.1 AK135965 mRNA Translation: BAE22749.1 BC011256 mRNA Translation: AAH11256.1 BC057967 mRNA Translation: AAH57967.1 BC061508 mRNA Translation: AAH61508.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS22183.1
PIRⁱ	A29941
NCBI Reference Sequences More...RefSeqⁱ	NP_032898.2, NM_008872.3
UniGeneⁱ	Mm.154660

Genome annotation databases

Ensemblⁱ	ENSMUST00000033941; ENSMUSP00000033941; ENSMUSG00000031538
GeneIDⁱ	18791
KEGGⁱ	mmu:18791
UCSC genome browser More...UCSCⁱ	uc009ldx.2 mouse

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P11214	Tissue-type plasminogen activator		RAT		559	UniRef90_P11214
UPI000A30B2BC		MUSPA		563
UPI0003D0B9AF		RAT		596

Protein	Similar proteins		Species	Score	Length	Source
P11214	Isoform 3 of Tissue-type plasminogen activator		HUMAN		516	UniRef50_P00750-3
Tissue-type plasminogen activator		PIG		562
Tissue-type plasminogen activator		BOVIN		566
Tissue-type plasminogen activator		RAT		559
Plasminogen activator		SAIBB		517
+115

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	J03520 mRNA Translation: AAA40470.1 AK135857 mRNA Translation: BAE22698.1 AK135965 mRNA Translation: BAE22749.1 BC011256 mRNA Translation: AAH11256.1 BC057967 mRNA Translation: AAH57967.1 BC061508 mRNA Translation: AAH61508.1
CCDSⁱ	CCDS22183.1
PIRⁱ	A29941
RefSeqⁱ	NP_032898.2, NM_008872.3
UniGeneⁱ	Mm.154660

3D structure databases

ProteinModelPortalⁱ	P11214
SMRⁱ	P11214
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

ComplexPortalⁱ	CPX-518 tPA-PAI-1 complex
IntActⁱ	P11214, 2 interactors
MINTⁱ	P11214
STRINGⁱ	10090.ENSMUSP00000033941

Chemistry databases

ChEMBLⁱ	CHEMBL3259492

ChEMBLⁱ

CHEMBL3259492

Protein family/group databases

MEROPSⁱ	S01.232

MEROPSⁱ

S01.232

PTM databases

iPTMnetⁱ	P11214
PhosphoSitePlusⁱ	P11214

Proteomic databases

MaxQBⁱ	P11214
PaxDbⁱ	P11214
PeptideAtlasⁱ	P11214
PRIDEⁱ	P11214

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000033941; ENSMUSP00000033941; ENSMUSG00000031538
GeneIDⁱ	18791
KEGGⁱ	mmu:18791
UCSCⁱ	uc009ldx.2 mouse

Organism-specific databases

CTDⁱ	5327
MGIⁱ	MGI:97610 Plat

Phylogenomic databases

eggNOGⁱ	KOG3627 Eukaryota COG5640 LUCA
GeneTreeⁱ	ENSGT00760000119133
HOGENOMⁱ	HOG000237314
HOVERGENⁱ	HBG008633
InParanoidⁱ	P11214
KOⁱ	K01343
OMAⁱ	PLVCMKD
OrthoDBⁱ	EOG091G0AH5
PhylomeDBⁱ	P11214
TreeFamⁱ	TF329901

Enzyme and pathway databases

BRENDAⁱ	3.4.21.68 3474
Reactomeⁱ	R-MMU-186797 Signaling by PDGF R-MMU-75205 Dissolution of Fibrin Clot

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P11214
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000031538 Expressed in 287 organ(s), highest expression level in primary oocyte
CleanExⁱ	MM_PLAT
Genevisibleⁱ	P11214 MM

Family and domain databases

CDDⁱ	cd00061 FN1, 1 hit cd00108 KR, 2 hits cd00190 Tryp_SPc, 1 hit
Gene3Dⁱ	2.40.20.10, 2 hits
InterProⁱ	View protein in InterPro IPR013032 EGF-like_CS IPR000742 EGF-like_dom IPR000083 Fibronectin_type1 IPR000001 Kringle IPR013806 Kringle-like IPR018056 Kringle_CS IPR038178 Kringle_sf IPR009003 Peptidase_S1_PA IPR001314 Peptidase_S1A IPR026280 Tissue_plasm_act IPR034811 tPA IPR001254 Trypsin_dom IPR018114 TRYPSIN_HIS IPR033116 TRYPSIN_SER
PANTHERⁱ	PTHR44617 PTHR44617, 1 hit
Pfamⁱ	View protein in Pfam PF00008 EGF, 1 hit PF00039 fn1, 1 hit PF00051 Kringle, 2 hits PF00089 Trypsin, 1 hit
PIRSFⁱ	PIRSF001145 Tissue_plasm_act, 1 hit
PRINTSⁱ	PR00722 CHYMOTRYPSIN
SMARTⁱ	View protein in SMART SM00181 EGF, 1 hit SM00058 FN1, 1 hit SM00130 KR, 2 hits SM00020 Tryp_SPc, 1 hit
SUPFAMⁱ	SSF50494 SSF50494, 1 hit SSF57440 SSF57440, 2 hits
PROSITEⁱ	View protein in PROSITE PS00022 EGF_1, 1 hit PS01186 EGF_2, 1 hit PS50026 EGF_3, 1 hit PS01253 FN1_1, 1 hit PS51091 FN1_2, 1 hit PS00021 KRINGLE_1, 2 hits PS50070 KRINGLE_2, 2 hits PS50240 TRYPSIN_DOM, 1 hit PS00134 TRYPSIN_HIS, 1 hit PS00135 TRYPSIN_SER, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	TPA_MOUSE
Accessionⁱ	P11214Primary (citable) accession number: P11214 Secondary accession number(s): Q6P7U0, Q91VP2
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
	Last sequence update:	October 2, 2007
	Last modified:	November 7, 2018
	This is version 182 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Peptidase families
Classification of peptidase families and list of entries
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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UniRef

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Supporting data

UniProtKB - P11214 (TPA_MOUSE)

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Tissue-type plasminogen activator

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ