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UniProtKB - P10972 (RL24_HALMA)
Protein
50S ribosomal protein L24
Gene
rpl24
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Functioni
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
By similarityStabilizes the tertiary rRNA structure within the 23S rRNA domain (domain I) to which it binds. Located at the polypeptide exit tunnel on the outside of the subunit.
GO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L24Alternative name(s): Hl15 Hl16 Hmal24 |
Gene namesi | Name:rpl24 Ordered Locus Names:rrnAC1601 |
Organismi | Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) |
Taxonomic identifieri | 272569 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Haloarculaceae › Haloarcula › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed2 Publications | |||
ChainiPRO_0000130767 | 2 – 120 | 50S ribosomal protein L24Add BLAST | 119 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit.
Interacts weakly with protein L4.
2 PublicationsProtein-protein interaction databases
IntActi | P10972, 3 interactors |
STRINGi | 272569.rrnAC1601 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P10972 |
SMRi | P10972 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P10972 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 26 | DisorderedSequence analysisAdd BLAST | 26 |
Sequence similaritiesi
Belongs to the universal ribosomal protein uL24 family.Curated
Phylogenomic databases
eggNOGi | arCOG04094, Archaea |
HOGENOMi | CLU_093240_2_1_2 |
OMAi | VRIMRGD |
Family and domain databases
CDDi | cd06089, KOW_RPL26, 1 hit |
Gene3Di | 2.30.30.30, 1 hit |
HAMAPi | MF_01326_A, Ribosomal_L24_A, 1 hit |
InterProi | View protein in InterPro IPR005824, KOW IPR041988, KOW_RPL26/RPL24 IPR014722, Rib_L2_dom2 IPR005825, Ribosomal_L24/26_CS IPR005756, Ribosomal_L26/L24P_euk/arc IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR11143, PTHR11143, 1 hit |
Pfami | View protein in Pfam PF00467, KOW, 1 hit PF16906, Ribosomal_L26, 1 hit |
SMARTi | View protein in SMART SM00739, KOW, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit |
TIGRFAMsi | TIGR01080, rplX_A_E, 1 hit |
PROSITEi | View protein in PROSITE PS01108, RIBOSOMAL_L24, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P10972-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKQPDKQRK SQRRAPLHER HKQVRATLSA DLREEYGQRN VRVNAGDTVE
60 70 80 90 100
VLRGDFAGEE GEVINVDLDK AVIHVEDVTL EKTDGEEVPR PLDTSNVRVT
110 120
DLDLEDEKRE ARLESEDDSA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 21 | H → R AA sequence (PubMed:3191994).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X55311 Genomic DNA Translation: CAA39019.1 AY596297 Genomic DNA Translation: AAV46518.1 |
PIRi | S10735, R5HS24 |
RefSeqi | WP_004957398.1, NZ_CP039138.1 |
Genome annotation databases
EnsemblBacteriai | AAV46518; AAV46518; rrnAC1601 |
GeneIDi | 40152566 64821826 |
KEGGi | hma:rrnAC1601 |
PATRICi | fig|272569.17.peg.2290 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X55311 Genomic DNA Translation: CAA39019.1 AY596297 Genomic DNA Translation: AAV46518.1 |
PIRi | S10735, R5HS24 |
RefSeqi | WP_004957398.1, NZ_CP039138.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1FFK | X-ray | 2.40 | Q | 2-120 | [»] | |
1JJ2 | X-ray | 2.40 | S | 2-120 | [»] | |
1K73 | X-ray | 3.01 | U | 2-120 | [»] | |
1K8A | X-ray | 3.00 | U | 2-120 | [»] | |
1K9M | X-ray | 3.00 | U | 2-120 | [»] | |
1KC8 | X-ray | 3.01 | U | 2-120 | [»] | |
1KD1 | X-ray | 3.00 | U | 2-120 | [»] | |
1KQS | X-ray | 3.10 | S | 2-120 | [»] | |
1M1K | X-ray | 3.20 | U | 2-120 | [»] | |
1M90 | X-ray | 2.80 | U | 2-120 | [»] | |
1ML5 | electron microscopy | 14.00 | u | 2-120 | [»] | |
1N8R | X-ray | 3.00 | U | 2-120 | [»] | |
1NJI | X-ray | 3.00 | U | 2-120 | [»] | |
1Q7Y | X-ray | 3.20 | U | 2-120 | [»] | |
1Q81 | X-ray | 2.95 | U | 2-120 | [»] | |
1Q82 | X-ray | 2.98 | U | 2-120 | [»] | |
1Q86 | X-ray | 3.00 | U | 2-120 | [»] | |
1QVF | X-ray | 3.10 | S | 2-120 | [»] | |
1QVG | X-ray | 2.90 | S | 2-120 | [»] | |
1S72 | X-ray | 2.40 | T | 1-120 | [»] | |
1VQ4 | X-ray | 2.70 | T | 1-120 | [»] | |
1VQ5 | X-ray | 2.60 | T | 1-120 | [»] | |
1VQ6 | X-ray | 2.70 | T | 1-120 | [»] | |
1VQ7 | X-ray | 2.50 | T | 1-120 | [»] | |
1VQ8 | X-ray | 2.20 | T | 1-120 | [»] | |
1VQ9 | X-ray | 2.40 | T | 1-120 | [»] | |
1VQK | X-ray | 2.30 | T | 1-120 | [»] | |
1VQL | X-ray | 2.30 | T | 1-120 | [»] | |
1VQM | X-ray | 2.30 | T | 1-120 | [»] | |
1VQN | X-ray | 2.40 | T | 1-120 | [»] | |
1VQO | X-ray | 2.20 | T | 1-120 | [»] | |
1VQP | X-ray | 2.25 | T | 1-120 | [»] | |
1W2B | X-ray | 3.50 | S | 2-120 | [»] | |
1YHQ | X-ray | 2.40 | T | 1-120 | [»] | |
1YI2 | X-ray | 2.65 | T | 1-120 | [»] | |
1YIJ | X-ray | 2.60 | T | 1-120 | [»] | |
1YIT | X-ray | 2.80 | T | 1-120 | [»] | |
1YJ9 | X-ray | 2.90 | T | 1-120 | [»] | |
1YJN | X-ray | 3.00 | T | 1-120 | [»] | |
1YJW | X-ray | 2.90 | T | 1-120 | [»] | |
2OTJ | X-ray | 2.90 | T | 1-120 | [»] | |
2OTL | X-ray | 2.70 | T | 1-120 | [»] | |
2QA4 | X-ray | 3.00 | T | 1-120 | [»] | |
2QEX | X-ray | 2.90 | T | 1-120 | [»] | |
3CC2 | X-ray | 2.40 | T | 1-120 | [»] | |
3CC4 | X-ray | 2.70 | T | 1-120 | [»] | |
3CC7 | X-ray | 2.70 | T | 1-120 | [»] | |
3CCE | X-ray | 2.75 | T | 1-120 | [»] | |
3CCJ | X-ray | 2.70 | T | 1-120 | [»] | |
3CCL | X-ray | 2.90 | T | 1-120 | [»] | |
3CCM | X-ray | 2.55 | T | 1-120 | [»] | |
3CCQ | X-ray | 2.90 | T | 1-120 | [»] | |
3CCR | X-ray | 3.00 | T | 1-120 | [»] | |
3CCS | X-ray | 2.95 | T | 1-120 | [»] | |
3CCU | X-ray | 2.80 | T | 1-120 | [»] | |
3CCV | X-ray | 2.90 | T | 1-120 | [»] | |
3CD6 | X-ray | 2.75 | T | 1-120 | [»] | |
3CMA | X-ray | 2.80 | T | 1-120 | [»] | |
3CME | X-ray | 2.95 | T | 1-120 | [»] | |
3CPW | X-ray | 2.70 | S | 1-120 | [»] | |
3CXC | X-ray | 3.00 | S | 2-120 | [»] | |
3G4S | X-ray | 3.20 | T | 2-120 | [»] | |
3G6E | X-ray | 2.70 | T | 2-120 | [»] | |
3G71 | X-ray | 2.85 | T | 2-120 | [»] | |
3I55 | X-ray | 3.11 | T | 1-120 | [»] | |
3I56 | X-ray | 2.90 | T | 1-120 | [»] | |
3OW2 | X-ray | 2.70 | S | 2-120 | [»] | |
4ADX | electron microscopy | 6.60 | T | 1-120 | [»] | |
4V42 | X-ray | 5.50 | BU | 2-120 | [»] | |
4V4R | X-ray | 5.90 | Y | 2-120 | [»] | |
4V4S | X-ray | 6.76 | BY | 2-120 | [»] | |
4V4T | X-ray | 6.46 | Y | 2-120 | [»] | |
4V9F | X-ray | 2.40 | T | 1-120 | [»] | |
AlphaFoldDBi | P10972 | |||||
SMRi | P10972 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | P10972, 3 interactors |
STRINGi | 272569.rrnAC1601 |
Genome annotation databases
EnsemblBacteriai | AAV46518; AAV46518; rrnAC1601 |
GeneIDi | 40152566 64821826 |
KEGGi | hma:rrnAC1601 |
PATRICi | fig|272569.17.peg.2290 |
Phylogenomic databases
eggNOGi | arCOG04094, Archaea |
HOGENOMi | CLU_093240_2_1_2 |
OMAi | VRIMRGD |
Miscellaneous databases
EvolutionaryTracei | P10972 |
Family and domain databases
CDDi | cd06089, KOW_RPL26, 1 hit |
Gene3Di | 2.30.30.30, 1 hit |
HAMAPi | MF_01326_A, Ribosomal_L24_A, 1 hit |
InterProi | View protein in InterPro IPR005824, KOW IPR041988, KOW_RPL26/RPL24 IPR014722, Rib_L2_dom2 IPR005825, Ribosomal_L24/26_CS IPR005756, Ribosomal_L26/L24P_euk/arc IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR11143, PTHR11143, 1 hit |
Pfami | View protein in Pfam PF00467, KOW, 1 hit PF16906, Ribosomal_L26, 1 hit |
SMARTi | View protein in SMART SM00739, KOW, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit |
TIGRFAMsi | TIGR01080, rplX_A_E, 1 hit |
PROSITEi | View protein in PROSITE PS01108, RIBOSOMAL_L24, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RL24_HALMA | |
Accessioni | P10972Primary (citable) accession number: P10972 Secondary accession number(s): Q5V1T4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1989 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 155 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families