Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 126 (02 Jun 2021)
Sequence version 1 (01 Jul 1989)
Previous versions | rss
Add a publicationFeedback
Protein

Agglutinin isolectin 3

Gene
N/A
Organism
Triticum aestivum (Wheat)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin.

Miscellaneous

The 4 sites proposed for binding to carbohydrates (N-acetyl-D-glucosamine) of receptor molecules are on the surface of the agglutinin molecule.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandChitin-binding, Lectin

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM18, Carbohydrate-Binding Module Family 18

UniLectin database of carbohydrate-binding proteins

More...
UniLectini
P10969

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Agglutinin isolectin 3
Alternative name(s):
WGA3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTriticum aestivum (Wheat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4565 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeTriticinaeTriticum
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000019116 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Protein family/group databases

Allergome; a platform for allergen knowledge

More...
Allergomei
650, Tri a 18

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000052591 – 171Agglutinin isolectin 3Add BLAST171
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_0000005260172 – 186Add BLAST15

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1Pyrrolidone carboxylic acid1 Publication1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi3 ↔ 18
Disulfide bondi12 ↔ 24
Disulfide bondi17 ↔ 31
Disulfide bondi35 ↔ 40
Disulfide bondi46 ↔ 61
Disulfide bondi55 ↔ 67
Disulfide bondi60 ↔ 74
Disulfide bondi78 ↔ 83
Disulfide bondi89 ↔ 104
Disulfide bondi98 ↔ 110
Disulfide bondi103 ↔ 117
Disulfide bondi121 ↔ 126
Disulfide bondi132 ↔ 147
Disulfide bondi141 ↔ 153
Disulfide bondi146 ↔ 160
Disulfide bondi164 ↔ 169
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi180N-linked (GlcNAc...) asparagine1

Keywords - PTMi

Disulfide bond, Glycoprotein, Pyrrolidone carboxylic acid

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P10969

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P10969, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer, u-shaped.

2 Publications

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1186
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P10969

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P10969

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 42Chitin-binding type-1 1PROSITE-ProRule annotationAdd BLAST42
Domaini43 – 85Chitin-binding type-1 2PROSITE-ProRule annotationAdd BLAST43
Domaini86 – 128Chitin-binding type-1 3PROSITE-ProRule annotationAdd BLAST43
Domaini129 – 171Chitin-binding type-1 4PROSITE-ProRule annotationAdd BLAST43

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni10 – 12Substrate bindingBy similarity3
Regioni62 – 73Substrate bindingAdd BLAST12
Regioni114 – 115Substrate binding2

Keywords - Domaini

Repeat

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
ANCGQWY

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.60.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001002, Chitin-bd_1
IPR018371, Chitin-binding_1_CS
IPR036861, Endochitinase-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00187, Chitin_bind_1, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00451, CHITINBINDNG

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00270, ChtBD1, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57016, SSF57016, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00026, CHIT_BIND_I_1, 4 hits
PS50941, CHIT_BIND_I_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P10969-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
QRCGEQGSGM ECPNNLCCSQ YGYCGMGGDY CGKGCQNGAC WTSKRCGSQA
60 70 80 90 100
GGKTCPNNHC CSQYGHCGFG AEYCGAGCQG GPCRADIKCG SQAGGKLCPN
110 120 130 140 150
NLCCSQWGYC GLGSEFCGEG CQNGACSTDK PCGKDAGGRV CTNNYCCSKW
160 170 180
GSCGIGPGYC GAGCQSGGCD GVFAEAIATN STLLAE
Length:186
Mass (Da):18,756
Last modified:July 1, 1989 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i68461A20339378FD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J02961 mRNA Translation: AAA34257.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A28401

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
TraesCAD_scaffold_137513_01G000100.1; TraesCAD_scaffold_137513_01G000100.1; TraesCAD_scaffold_137513_01G000100
TraesCLE_scaffold_122568_01G000100.1; TraesCLE_scaffold_122568_01G000100.1; TraesCLE_scaffold_122568_01G000100
TraesPAR_scaffold_127396_01G000100.1; TraesPAR_scaffold_127396_01G000100.1; TraesPAR_scaffold_127396_01G000100
TraesROB_scaffold_145157_01G000100.1; TraesROB_scaffold_145157_01G000100.1; TraesROB_scaffold_145157_01G000100
TraesWEE_scaffold_016939_01G000300.1; TraesWEE_scaffold_016939_01G000300.1; TraesWEE_scaffold_016939_01G000300

Gramene; a comparative resource for plants

More...
Gramenei
TraesCAD_scaffold_137513_01G000100.1; TraesCAD_scaffold_137513_01G000100.1; TraesCAD_scaffold_137513_01G000100
TraesCLE_scaffold_122568_01G000100.1; TraesCLE_scaffold_122568_01G000100.1; TraesCLE_scaffold_122568_01G000100
TraesPAR_scaffold_127396_01G000100.1; TraesPAR_scaffold_127396_01G000100.1; TraesPAR_scaffold_127396_01G000100
TraesROB_scaffold_145157_01G000100.1; TraesROB_scaffold_145157_01G000100.1; TraesROB_scaffold_145157_01G000100
TraesWEE_scaffold_016939_01G000300.1; TraesWEE_scaffold_016939_01G000300.1; TraesWEE_scaffold_016939_01G000300

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02961 mRNA Translation: AAA34257.1
PIRiA28401

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1K7TX-ray2.40A/B1-186[»]
1K7UX-ray2.20A/B1-186[»]
1K7VX-ray2.20A/B2-186[»]
1WGTX-ray1.90A/B2-186[»]
2X52X-ray1.70A/B2-171[»]
SMRiP10969
ModBaseiSearch...
PDBe-KBiSearch...

Protein family/group databases

Allergomei650, Tri a 18
CAZyiCBM18, Carbohydrate-Binding Module Family 18
UniLectiniP10969

Proteomic databases

PRIDEiP10969

Genome annotation databases

EnsemblPlantsiTraesCAD_scaffold_137513_01G000100.1; TraesCAD_scaffold_137513_01G000100.1; TraesCAD_scaffold_137513_01G000100
TraesCLE_scaffold_122568_01G000100.1; TraesCLE_scaffold_122568_01G000100.1; TraesCLE_scaffold_122568_01G000100
TraesPAR_scaffold_127396_01G000100.1; TraesPAR_scaffold_127396_01G000100.1; TraesPAR_scaffold_127396_01G000100
TraesROB_scaffold_145157_01G000100.1; TraesROB_scaffold_145157_01G000100.1; TraesROB_scaffold_145157_01G000100
TraesWEE_scaffold_016939_01G000300.1; TraesWEE_scaffold_016939_01G000300.1; TraesWEE_scaffold_016939_01G000300
GrameneiTraesCAD_scaffold_137513_01G000100.1; TraesCAD_scaffold_137513_01G000100.1; TraesCAD_scaffold_137513_01G000100
TraesCLE_scaffold_122568_01G000100.1; TraesCLE_scaffold_122568_01G000100.1; TraesCLE_scaffold_122568_01G000100
TraesPAR_scaffold_127396_01G000100.1; TraesPAR_scaffold_127396_01G000100.1; TraesPAR_scaffold_127396_01G000100
TraesROB_scaffold_145157_01G000100.1; TraesROB_scaffold_145157_01G000100.1; TraesROB_scaffold_145157_01G000100
TraesWEE_scaffold_016939_01G000300.1; TraesWEE_scaffold_016939_01G000300.1; TraesWEE_scaffold_016939_01G000300

Phylogenomic databases

OMAiANCGQWY

Miscellaneous databases

EvolutionaryTraceiP10969

Protein Ontology

More...
PROi
PR:P10969

Gene expression databases

ExpressionAtlasiP10969, baseline

Family and domain databases

Gene3Di3.30.60.10, 4 hits
InterProiView protein in InterPro
IPR001002, Chitin-bd_1
IPR018371, Chitin-binding_1_CS
IPR036861, Endochitinase-like_sf
PfamiView protein in Pfam
PF00187, Chitin_bind_1, 4 hits
PRINTSiPR00451, CHITINBINDNG
SMARTiView protein in SMART
SM00270, ChtBD1, 4 hits
SUPFAMiSSF57016, SSF57016, 4 hits
PROSITEiView protein in PROSITE
PS00026, CHIT_BIND_I_1, 4 hits
PS50941, CHIT_BIND_I_2, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAGI3_WHEAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P10969
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: June 2, 2021
This is version 126 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again