UniProtKB - P10968 (AGI1_WHEAT)
Protein
Agglutinin isolectin 1
Gene
N/A
Organism
Triticum aestivum (Wheat)
Status
Functioni
N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin.
Miscellaneous
The 4 sites proposed for binding to carbohydrates (N-acetyl-D-glucosamine) of receptor molecules are on the surface of the agglutinin molecule.
GO - Molecular functioni
- carbohydrate binding Source: UniProtKB-KW
- chitin binding Source: UniProtKB-KW
Keywordsi
Ligand | Chitin-binding, Lectin |
Protein family/group databases
CAZyi | CBM18, Carbohydrate-Binding Module Family 18 |
UniLectini | P10968 |
Names & Taxonomyi
Protein namesi | Recommended name: Agglutinin isolectin 1Alternative name(s): Isolectin A WGA1 |
Organismi | Triticum aestivum (Wheat) |
Taxonomic identifieri | 4565 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Pooideae › Triticodae › Triticeae › Triticinae › Triticum |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 26 | 1 PublicationAdd BLAST | 26 | |
ChainiPRO_0000005255 | 27 – 197 | Agglutinin isolectin 1Add BLAST | 171 | |
PropeptideiPRO_0000005256 | 198 – 212 | Add BLAST | 15 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 27 | Pyrrolidone carboxylic acid1 Publication | 1 | |
Disulfide bondi | 29 ↔ 44 | |||
Disulfide bondi | 38 ↔ 50 | |||
Disulfide bondi | 43 ↔ 57 | |||
Disulfide bondi | 61 ↔ 66 | |||
Disulfide bondi | 72 ↔ 87 | |||
Disulfide bondi | 81 ↔ 93 | |||
Disulfide bondi | 86 ↔ 100 | |||
Disulfide bondi | 104 ↔ 109 | |||
Disulfide bondi | 115 ↔ 130 | |||
Disulfide bondi | 124 ↔ 136 | |||
Disulfide bondi | 129 ↔ 143 | |||
Disulfide bondi | 147 ↔ 152 | |||
Disulfide bondi | 158 ↔ 173 | |||
Disulfide bondi | 167 ↔ 179 | |||
Disulfide bondi | 172 ↔ 186 | |||
Disulfide bondi | 190 ↔ 195 |
Keywords - PTMi
Disulfide bond, Pyrrolidone carboxylic acidProteomic databases
PRIDEi | P10968 |
Interactioni
Subunit structurei
Homodimer, u-shaped.
1 PublicationProtein-protein interaction databases
STRINGi | 4565.Traes_1AL_B8B0A092C.1 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P10968 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P10968 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 27 – 68 | Chitin-binding type-1 1PROSITE-ProRule annotationAdd BLAST | 42 | |
Domaini | 69 – 111 | Chitin-binding type-1 2PROSITE-ProRule annotationAdd BLAST | 43 | |
Domaini | 112 – 154 | Chitin-binding type-1 3PROSITE-ProRule annotationAdd BLAST | 43 | |
Domaini | 155 – 197 | Chitin-binding type-1 4PROSITE-ProRule annotationAdd BLAST | 43 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 36 – 38 | Substrate binding | 3 | |
Regioni | 88 – 99 | Substrate bindingAdd BLAST | 12 | |
Regioni | 140 – 141 | Substrate binding | 2 |
Keywords - Domaini
Repeat, SignalPhylogenomic databases
eggNOGi | ENOG502S7G0, Eukaryota |
HOGENOMi | CLU_112193_0_0_1 |
OMAi | AGNCGPQ |
Family and domain databases
Gene3Di | 3.30.60.10, 4 hits |
InterProi | View protein in InterPro IPR001002, Chitin-bd_1 IPR018371, Chitin-binding_1_CS IPR036861, Endochitinase-like_sf |
Pfami | View protein in Pfam PF00187, Chitin_bind_1, 4 hits |
PRINTSi | PR00451, CHITINBINDNG |
SMARTi | View protein in SMART SM00270, ChtBD1, 4 hits |
SUPFAMi | SSF57016, SSF57016, 4 hits |
PROSITEi | View protein in PROSITE PS00026, CHIT_BIND_I_1, 4 hits PS50941, CHIT_BIND_I_2, 4 hits |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P10968-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKMMSTRALA LGAAAVLAFA AATAQAQRCG EQGSNMECPN NLCCSQYGYC
60 70 80 90 100
GMGGDYCGKG CQNGACWTSK RCGSQAGGAT CTNNQCCSQY GYCGFGAEYC
110 120 130 140 150
GAGCQGGPCR ADIKCGSQAG GKLCPNNLCC SQWGFCGLGS EFCGGGCQSG
160 170 180 190 200
ACSTDKPCGK DAGGRVCTNN YCCSKWGSCG IGPGYCGAGC QSGGCDGVFA
210
EAITANSTLL QE
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 63 | N → D AA sequence (PubMed:2499688).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M25536 mRNA Translation: AAA34256.1 |
PIRi | S09623 |
Genome annotation databases
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M25536 mRNA Translation: AAA34256.1 |
PIRi | S09623 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1WGC | X-ray | 2.20 | A/B | 28-197 | [»] | |
2CWG | X-ray | 2.00 | A/B | 28-197 | [»] | |
2UVO | X-ray | 1.40 | A/B/E/F | 28-197 | [»] | |
2X3T | X-ray | 2.75 | A/B/C/D | 28-197 | [»] | |
4AML | X-ray | 1.60 | A/B | 28-197 | [»] | |
7WGA | X-ray | 2.00 | A/B | 28-197 | [»] | |
SMRi | P10968 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 4565.Traes_1AL_B8B0A092C.1 |
Protein family/group databases
Allergomei | 3501, Tri a 18.0101 650, Tri a 18 |
CAZyi | CBM18, Carbohydrate-Binding Module Family 18 |
UniLectini | P10968 |
Proteomic databases
PRIDEi | P10968 |
Genome annotation databases
Phylogenomic databases
eggNOGi | ENOG502S7G0, Eukaryota |
HOGENOMi | CLU_112193_0_0_1 |
OMAi | AGNCGPQ |
Miscellaneous databases
EvolutionaryTracei | P10968 |
PROi | PR:P10968 |
Family and domain databases
Gene3Di | 3.30.60.10, 4 hits |
InterProi | View protein in InterPro IPR001002, Chitin-bd_1 IPR018371, Chitin-binding_1_CS IPR036861, Endochitinase-like_sf |
Pfami | View protein in Pfam PF00187, Chitin_bind_1, 4 hits |
PRINTSi | PR00451, CHITINBINDNG |
SMARTi | View protein in SMART SM00270, ChtBD1, 4 hits |
SUPFAMi | SSF57016, SSF57016, 4 hits |
PROSITEi | View protein in PROSITE PS00026, CHIT_BIND_I_1, 4 hits PS50941, CHIT_BIND_I_2, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AGI1_WHEAT | |
Accessioni | P10968Primary (citable) accession number: P10968 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1989 |
Last sequence update: | November 1, 1990 | |
Last modified: | December 2, 2020 | |
This is version 142 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references