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Protein

Protein MAK16

Gene

MAK16

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Its role might be as part of the apparatus concerned with the nuclear events of the cell cycle.1 Publication

GO - Biological processi

  • cell cycle Source: UniProtKB-KW
  • maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD
  • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD
  • ribosomal large subunit biogenesis Source: SGD

Keywordsi

Biological processCell cycle

Enzyme and pathway databases

BioCyciYEAST:G3O-28836-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MAK16
Alternative name(s):
Maintenance of killer protein 16
Gene namesi
Name:MAK16
Ordered Locus Names:YAL025C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:YAL025C
SGDiS000000023 MAK16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002037931 – 306Protein MAK16Add BLAST306

Proteomic databases

MaxQBiP10962
PaxDbiP10962
PRIDEiP10962

PTM databases

iPTMnetiP10962

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi31741, 327 interactors
DIPiDIP-6521N
IntActiP10962, 13 interactors
MINTiP10962
STRINGi4932.YAL025C

Structurei

Secondary structure

1306
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 11Combined sources8
Beta strandi18 – 20Combined sources3
Beta strandi26 – 28Combined sources3
Beta strandi34 – 37Combined sources4
Turni40 – 42Combined sources3
Turni44 – 46Combined sources3
Beta strandi48 – 58Combined sources11
Beta strandi60 – 65Combined sources6
Helixi67 – 70Combined sources4
Beta strandi77 – 81Combined sources5
Helixi86 – 96Combined sources11
Turni97 – 99Combined sources3
Helixi102 – 116Combined sources15
Turni117 – 120Combined sources4
Helixi121 – 126Combined sources6
Helixi141 – 144Combined sources4
Turni145 – 148Combined sources4
Helixi149 – 156Combined sources8
Helixi158 – 170Combined sources13
Turni171 – 173Combined sources3

3D structure databases

ProteinModelPortaliP10962
SMRiP10962
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati213 – 22018
Repeati222 – 22928

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni213 – 2292 X 8 AA repeatsAdd BLAST17
Regioni251 – 2647 X 2 AA repeats of S-[DE]Add BLAST14

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi139 – 144Nuclear localization signalSequence analysis6
Motifi282 – 287Nuclear localization signalSequence analysis6

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi195 – 235Asp/Glu-rich (acidic)Add BLAST41

Sequence similaritiesi

Belongs to the MAK16 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

GeneTreeiENSGT00390000012859
HOGENOMiHOG000201538
InParanoidiP10962
KOiK14831
OMAiDIYNFSQ
OrthoDBiEOG092C4P58

Family and domain databases

InterProiView protein in InterPro
IPR029004 L28e/Mak16
IPR006958 Mak16
PfamiView protein in Pfam
PF04874 Mak16, 1 hit
PF01778 Ribosomal_L28e, 1 hit
PIRSFiPIRSF003352 MAK16, 1 hit

Sequencei

Sequence statusi: Complete.

P10962-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDEIVWQVI NQSFCSHRIK APNGQNFCRN EYNVTGLCTR QSCPLANSKY
60 70 80 90 100
ATVKCDNGKL YLYMKTPERA HTPAKLWERI KLSKNYTKAL QQIDEHLLHW
110 120 130 140 150
SKFFRHKCKQ RFTKLTQVMI TERRLALREE ERHYVGVAPK VKRREQNRER
160 170 180 190 200
KALVAAKIEK AIEKELMDRL KSGAYGDKPL NVDEKVWKKI MGQMEEENSQ
210 220 230 240 250
DEEEDWDEEE ESDDGEVEYV ADDGEGEYVD VDDLEKWLAD SDREASSASE
260 270 280 290 300
SESDSESESD SDSDEENKNS AKRRKKGTSA KTKRPKVEIE YEEEHEVQNA

EQEVAQ
Length:306
Mass (Da):35,696
Last modified:July 27, 2011 - v2
Checksum:i309ED6897EA24F73
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti250E → Q in AAA34752 (PubMed:3045810).Curated1
Sequence conflicti250E → Q in AAC05007 (PubMed:7731988).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03852 Genomic DNA Translation: AAA34752.1
U12980 Genomic DNA Translation: AAC05007.1
BK006935 Genomic DNA Translation: DAA06963.2
PIRiA35588 BVBYK6
RefSeqiNP_009377.2, NM_001178170.2

Genome annotation databases

EnsemblFungiiYAL025C; YAL025C; YAL025C
GeneIDi851208
KEGGisce:YAL025C

Similar proteinsi

Entry informationi

Entry nameiMAK16_YEAST
AccessioniPrimary (citable) accession number: P10962
Secondary accession number(s): D6VPJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 27, 2011
Last modified: July 18, 2018
This is version 151 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome I
    Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

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