UniProtKB - P10928 (BP10_BPT4)
Baseplate wedge protein gp10
10
Functioni
Peripheral baseplate protein that is part of the tail fiber network. Connects the short tail fibers to the baseplate (PubMed:16554069).
During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors. Involved in the tail assembly.
1 Publication2 PublicationsGO - Biological processi
- viral release from host cell Source: InterPro
- viral tail assembly Source: UniProtKB-KW
Keywordsi
Biological process | Viral release from host cell, Viral tail assembly |
Protein family/group databases
TCDBi | 1.K.1.1.1, the gp27/5 t4-baseplate (t4-bp) family |
Names & Taxonomyi
Protein namesi | Recommended name: Baseplate wedge protein gp10UniRule annotationCuratedAlternative name(s): Gene product 10Curated Short name: gp10 |
Gene namesi | Name:10 |
Organismi | Enterobacteria phage T4 (Bacteriophage T4) |
Taxonomic identifieri | 10665 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes › Caudovirales › Myoviridae › Tevenvirinae › Tequatrovirus |
Virus hosti | Escherichia coli [TaxID: 562] |
Proteomesi |
|
Subcellular locationi
- Virion UniRule annotation3 Publications Note: Present in 18 copies in the baseplate.1 Publication
Keywords - Cellular componenti
Viral baseplate protein, Viral tail protein, VirionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000165000 | 1 – 602 | Baseplate wedge protein gp10Add BLAST | 602 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 555 | Interchain (with C-187 in GP7); alternate1 Publication | ||
Disulfide bondi | 555 | Interchain; alternateUniRule annotation1 Publication |
Keywords - PTMi
Disulfide bondExpressioni
Inductioni
Keywords - Developmental stagei
Late proteinInteractioni
Subunit structurei
Homotrimer; disulfide-linked (PubMed:19896486, PubMed:27193680). Heteromultimer with gp7 (PubMed:19896486, PubMed:27193680); a gp10 molecule is disulfide-linked to gp7 and the other two remaining gp10 molecules form a disulfide bond (PubMed:27193680). The gp10 trimer interacts with gp11 trimer and with the short tail fiber (STF) composed of the gp12 trimer (PubMed:27193680). Part of the baseplate macromolecular complex which consists of gp5, gp5.4, gp27 (central spike complex); gp6, gp25, gp53 (inner baseplate); gp7, gp8 (intermediate baseplate); gp9, gp10, gp11, gp12 (peripheral); gp48 and gp54 (proximal region of the tail tube) (PubMed:27193680).
UniRule annotation2 PublicationsStructurei
Secondary structure
3D structure databases
SMRi | P10928 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P10928 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 501 – 523 | DisorderedSequence analysisAdd BLAST | 23 |
Sequence similaritiesi
Family and domain databases
Gene3Di | 2.60.120.640, 1 hit |
HAMAPi | MF_04106, BP10_T4, 1 hit |
InterProi | View protein in InterPro IPR008987, Baseplate_struct_prot_Gp9/10 IPR034695, BP10_T4 IPR036240, Gp9-like_sf IPR027411, Gp9/Gp10_mid_dom_sf |
Pfami | View protein in Pfam PF07880, T4_gp9_10, 1 hit |
SUPFAMi | SSF50017, SSF50017, 1 hit |
i Sequence
Sequence statusi: Complete.
10 20 30 40 50
MKQNINIGNV VDDGTGDYLR KGGIKINENF DELYYELGDG DVPYSAGAWK
60 70 80 90 100
TYNASSGQTL TAEWGKSYAI NTSSGRVTIN LPKGTVNDYN KVIRARDVFA
110 120 130 140 150
TWNVNPVTLV AASGDTIKGS AVPVEINVRF SDLELVYCAP GRWEYVKNKQ
160 170 180 190 200
IDKITSSDIS NVARKEFLVE VQGQTDFLDV FRGTSYNVNN IRVKHRGNEL
210 220 230 240 250
YYGDVFSENS DFGSPGENEG ELVPLDGFNI RLRQPCNIGD TVQIETFMDG
260 270 280 290 300
VSQWRSSYTR RQIRLLDSKL TSKTSLEGSI YVTDLSTMKS IPFSAFGLIP
310 320 330 340 350
GEPINPNSLE VRFNGILQEL AGTVGMPLFH CVGADSDDEV ECSVLGGTWE
360 370 380 390 400
QSHTDYSVET DENGIPEILH FDSVFEHGDI INITWFNNDL GTLLTKDEII
410 420 430 440 450
DETDNLYVSQ GPGVDISGDV NLTDFDKIGW PNVEAVQSYQ RAFNAVSNIF
460 470 480 490 500
DTIYPIGTIY ENAVNPNNPV TYMGFGSWKL FGQGKVLVGW NEDISDPNFA
510 520 530 540 550
LNNNDLDSGG NPSHTAGGTG GSTSVTLENA NLPATETDEE VLIVDENGSV
560 570 580 590 600
IVGGCQYDPD ESGPIYTKYR EAKASTNSTH TPPTSITNIQ PYITVYRWIR
IA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X14192 Genomic DNA Translation: CAA32396.1 AF158101 Genomic DNA Translation: AAD42415.1 M26253 Genomic DNA Translation: AAA32493.1 |
PIRi | S04083, GEBPT4 |
RefSeqi | NP_049768.1, NC_000866.4 |
Genome annotation databases
GeneIDi | 1258808 |
KEGGi | vg:1258808 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X14192 Genomic DNA Translation: CAA32396.1 AF158101 Genomic DNA Translation: AAD42415.1 M26253 Genomic DNA Translation: AAA32493.1 |
PIRi | S04083, GEBPT4 |
RefSeqi | NP_049768.1, NC_000866.4 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2FKK | X-ray | 1.20 | A | 397-602 | [»] | |
2FL8 | electron microscopy | 1.20 | A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R | 1-602 | [»] | |
2FL9 | electron microscopy | 17.00 | A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R | 1-602 | [»] | |
5HX2 | electron microscopy | 3.80 | G/H/I | 1-602 | [»] | |
5IV5 | electron microscopy | 4.11 | AC/AD/AE/CF/CG/CH/EI/EJ/FA/HB/HC/HD/I/J/K/f/g/h | 1-602 | [»] | |
5IV7 | electron microscopy | 6.77 | AE/AF/AG/CG/DA/DB/FB/FC/FD/I/J/K/Y/Z/a/o/p/q | 1-602 | [»] | |
SMRi | P10928 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein family/group databases
TCDBi | 1.K.1.1.1, the gp27/5 t4-baseplate (t4-bp) family |
Genome annotation databases
GeneIDi | 1258808 |
KEGGi | vg:1258808 |
Miscellaneous databases
EvolutionaryTracei | P10928 |
Family and domain databases
Gene3Di | 2.60.120.640, 1 hit |
HAMAPi | MF_04106, BP10_T4, 1 hit |
InterProi | View protein in InterPro IPR008987, Baseplate_struct_prot_Gp9/10 IPR034695, BP10_T4 IPR036240, Gp9-like_sf IPR027411, Gp9/Gp10_mid_dom_sf |
Pfami | View protein in Pfam PF07880, T4_gp9_10, 1 hit |
SUPFAMi | SSF50017, SSF50017, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | BP10_BPT4 | |
Accessioni | P10928Primary (citable) accession number: P10928 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1989 |
Last sequence update: | July 1, 1989 | |
Last modified: | September 29, 2021 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families