UniProtKB - P10835 (MTC3_PBCVC)
Protein
Modification methylase CviBIII
Gene
CVIBIIIM
Organism
Paramecium bursaria Chlorella virus NC1A (PBCV-NC1A)
Status
Functioni
This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands.
Catalytic activityi
- a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N6-methyl-2'-deoxyadenosine in DNA + H+ + S-adenosyl-L-homocysteineEC:2.1.1.72
GO - Molecular functioni
- DNA binding Source: InterPro
- N-methyltransferase activity Source: InterPro
- site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC
Keywordsi
Molecular function | Methyltransferase, Transferase |
Ligand | S-adenosyl-L-methionine |
Protein family/group databases
REBASEi | 752, M.CviBIII |
Names & Taxonomyi
Protein namesi | Recommended name: Modification methylase CviBIII (EC:2.1.1.72)Short name: M.CviBIII Alternative name(s): Adenine-specific methyltransferase CviBIII |
Gene namesi | Name:CVIBIIIM |
Organismi | Paramecium bursaria Chlorella virus NC1A (PBCV-NC1A) |
Taxonomic identifieri | 46020 [NCBI] |
Taxonomic lineagei | Viruses › Varidnaviria › Bamfordvirae › Nucleocytoviricota › Megaviricetes › Algavirales › Phycodnaviridae › Chlorovirus |
Virus hosti | Chlorella [TaxID: 3071] |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000087948 | 1 – 377 | Modification methylase CviBIIIAdd BLAST | 377 |
Family & Domainsi
Sequence similaritiesi
Belongs to the N(4)/N(6)-methyltransferase family.Curated
Family and domain databases
InterProi | View protein in InterPro IPR003356, DNA_methylase_A-5 IPR002052, DNA_methylase_N6_adenine_CS IPR029063, SAM-dependent_MTases |
Pfami | View protein in Pfam PF02384, N6_Mtase, 1 hit |
SUPFAMi | SSF53335, SSF53335, 1 hit |
PROSITEi | View protein in PROSITE PS00092, N6_MTASE, 1 hit |
i Sequence
Sequence statusi: Complete.
P10835-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNVEQYTQVT TDFEKTLTKE KKSKQGIFFT PKTVREKLFG FTEHFQNTPG
60 70 80 90 100
FSILEPSCGT GEIISECVER FPLASIKGVE LDNDMSTICS KKYAEYNVDI
110 120 130 140 150
VNEDFLLWKG GKFDFIVGNP PYVVRPSGYK NDNRIAKGRS NLYVEFLYKC
160 170 180 190 200
ITEHLKEDGI LAFIIPSTIG NSSFYEPIRK LIITLDILSF EILDKHDFCD
210 220 230 240 250
TNTRLCSIVI KNSPGTGKYT YRDYICDKDI PHHGNSYIGS LDLKFKTGFA
260 270 280 290 300
WANVNKFFTD KSEIPFFTSS NIKLNEIHIG DKMKYLTQDT TKFFTGKALL
310 320 330 340 350
IKTASAGKRG GRFEFGFSLY ENDKWAVDND IIVIQGPDTV LSIVQDVLMK
360 370
DVTNEFINIL VNNGHISMKL LKSIPLF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X06618 Genomic DNA Translation: CAA29835.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X06618 Genomic DNA Translation: CAA29835.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
REBASEi | 752, M.CviBIII |
Family and domain databases
InterProi | View protein in InterPro IPR003356, DNA_methylase_A-5 IPR002052, DNA_methylase_N6_adenine_CS IPR029063, SAM-dependent_MTases |
Pfami | View protein in Pfam PF02384, N6_Mtase, 1 hit |
SUPFAMi | SSF53335, SSF53335, 1 hit |
PROSITEi | View protein in PROSITE PS00092, N6_MTASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MTC3_PBCVC | |
Accessioni | P10835Primary (citable) accession number: P10835 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1989 |
Last sequence update: | July 1, 1989 | |
Last modified: | August 12, 2020 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |
Miscellaneousi
Documents
- Restriction enzymes and methylases
Classification of restriction enzymes and methylases and list of entries - SIMILARITY comments
Index of protein domains and families