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Protein

Packaging protein UL32

Gene

UL32

Organism
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role in efficient localization of neo-synthesized capsids to nuclear replication compartments, thereby controlling cleavage and packaging of virus genomic DNA.2 Publications

Caution

Was originally thought to be an envelope glycoprotein.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Packaging protein UL32
Gene namesi
Name:UL32
OrganismiHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Taxonomic identifieri10299 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000009294 Componenti: Genome

Subcellular locationi

  • Host cytoplasm 1 Publication
  • Host nucleus 1 Publication
  • Note: Mainly cytoplasmic in transfected cell culture.

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm, Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001160141 – 596Packaging protein UL32Add BLAST596

Proteomic databases

PRIDEiP10216

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
UL15F8RFH02EBI-9645871,EBI-9642200From Human herpesvirus 1.

Protein-protein interaction databases

IntActiP10216, 7 interactors
MINTiP10216

Structurei

3D structure databases

SMRiP10216
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae UL32 protein family.Curated

Phylogenomic databases

OrthoDBiVOG0900008B

Family and domain databases

InterProiView protein in InterPro
IPR002597 Herpes_env
PfamiView protein in Pfam
PF01673 Herpes_env, 1 hit

Sequencei

Sequence statusi: Complete.

P10216-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATSPPGVLA SVAVCEESPG SSWKAGAFER AYVAFDPSLL ALNEALCAEL
60 70 80 90 100
LTASHVIGVP PVGTLDEDVA ADVVTAPSRA RGGAGDGGGS GGRGGPRNPP
110 120 130 140 150
PDPCGEGLLD TGPFSAAAID TFALDRPCLV CRTIELYKQT YRLSPQWVAD
160 170 180 190 200
YAFLCAKCLG APHCAASIFV AAFEFVYVMD RHFLRTKKAT LVGSFARFAL
210 220 230 240 250
TINDIHRHFF LHCCFRTDGG VPGRHAQKQP KPSPSPGAAK VQYSNYSFLA
260 270 280 290 300
QSATRALIGT LASGGEEGAG SAAGSGTQPS LTTALMNWKD CARLLDCTEG
310 320 330 340 350
RRGGGDSCCT RAAARNGEFE TVAGDREPEE SPDTWAYADL VLLLLAGTPA
360 370 380 390 400
VWESGPQLRA AAEARRATVR QSWEAHRGAR TRDVAPRFAQ FTEPDAQPDL
410 420 430 440 450
DLGPLMATVL KHGRGRGRTG GECLLCNLLL VRAYWLALRR LRASVVRYSE
460 470 480 490 500
NNTSLFDCIV PVVDQLEADP ETQPGDGGRF VSLLRAAGPE AIFKHMFCDP
510 520 530 540 550
MCAITEMEVD PWVLFGHPPA THPDELLLHK AKLACGNEFE GRVCIALRAL
560 570 580 590
IYTFKTYQVF VPKPTALATF VREAGALLRR HSISLLSLEH TLCTYV
Length:596
Mass (Da):63,950
Last modified:July 1, 1989 - v1
Checksum:i6E650D5EE9CB09B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14112 Genomic DNA Translation: CAA32307.1
PIRiE30085 WMBEH2
RefSeqiYP_009137107.1, NC_001806.2

Genome annotation databases

GeneIDi2703352
KEGGivg:2703352

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14112 Genomic DNA Translation: CAA32307.1
PIRiE30085 WMBEH2
RefSeqiYP_009137107.1, NC_001806.2

3D structure databases

SMRiP10216
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP10216, 7 interactors
MINTiP10216

Proteomic databases

PRIDEiP10216

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2703352
KEGGivg:2703352

Phylogenomic databases

OrthoDBiVOG0900008B

Family and domain databases

InterProiView protein in InterPro
IPR002597 Herpes_env
PfamiView protein in Pfam
PF01673 Herpes_env, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiUL32_HHV11
AccessioniPrimary (citable) accession number: P10216
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: July 18, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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