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Protein

Capsid vertex component 1

Gene

CVC1

Organism
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.UniRule annotation2 Publications

GO - Biological processi

Keywordsi

Biological processViral genome packaging, Viral release from host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid vertex component 1UniRule annotation
Gene namesi
Name:CVC1UniRule annotation
Ordered Locus Names:UL17
OrganismiHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Taxonomic identifieri10299 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000009294 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001159581 – 703Capsid vertex component 1Add BLAST703

Proteomic databases

PRIDEiP10201

Expressioni

Keywords - Developmental stagei

Late protein

Interactioni

Subunit structurei

Interacts (via C-terminus) with capsid vertex component 2/CVC2.UniRule annotation1 Publication

Protein-protein interaction databases

BioGridi971425, 8 interactors
DIPiDIP-60386N
IntActiP10201, 2 interactors

Structurei

3D structure databases

SMRiP10201
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae CVC1 protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG0900002R

Family and domain databases

HAMAPiMF_04017 HSV_CVC1, 1 hit
InterProiView protein in InterPro
IPR007640 UL17-like
PfamiView protein in Pfam
PF04559 Herpes_UL17, 1 hit

Sequencei

Sequence statusi: Complete.

P10201-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNAHLANEVQ TISATARVGP RSLVHVIISS ECLAAAGIPL AALMRGRPGL
60 70 80 90 100
GTAANFQVEI QTRAHATGDC TPWCTAFAAY VPADAVGELL APVVPAHPGL
110 120 130 140 150
LPRASSAGGL FVSLPVVCDA QGVYDPYAVA ALRLAWGSGA SCARVILFSY
160 170 180 190 200
DELVPPNTRY AADSTRIMRV CRHLCRYVAL LGAAAPPAAK EAAAHLSMGL
210 220 230 240 250
GESASPRPQP LARPHAGAPA DPPIVGASDP PISPEEQLTA PGGDTTAAQD
260 270 280 290 300
VSIAQENEEI LALVQRAVQD VTRRHPVRAR TGRAACGVAS GLRQGALVHQ
310 320 330 340 350
AVSGGAMGAA DADAVLAGLE PPGGGRFVAP APHGPGGEDI LNDVLTLTPG
360 370 380 390 400
TAKPRSLVEW LDRGWEALAG GDRPDWLWSR RSISVVLRHH YGTKQRFVVV
410 420 430 440 450
SYENSVAWGG RRARPPLLSS ALATALTEAC AAERVVRPHQ LSPAGQAELL
460 470 480 490 500
LRFPALEVPL RHPRPVLPPF DIAAEVAFTA RIHLACLRAL GQAIRAALQG
510 520 530 540 550
GPRISQRLRY DFGPDQRAWL GEVTRRFPIL LENLMRAVEG TAPDAFFHTA
560 570 580 590 600
YALAVLAHLG GRGGRGRRVV PLGDDLPARF ADSDGHYVFD YYSTSGDTLR
610 620 630 640 650
LNNRPIAVAM DGDVSKREQS KCRFMEAVPS TAPRRVCEQY LPGESYAYLC
660 670 680 690 700
LGFNRRLCGI VVFPGGFAFT INIAAYLSLS DPVARAAVLR FCRKVSSGNG

RSR
Length:703
Mass (Da):74,582
Last modified:July 1, 1989 - v1
Checksum:i536DAF5421BD6B4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14112 Genomic DNA Translation: CAA32329.1
PIRiH30083 WMBET7

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14112 Genomic DNA Translation: CAA32329.1
PIRiH30083 WMBET7

3D structure databases

SMRiP10201
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi971425, 8 interactors
DIPiDIP-60386N
IntActiP10201, 2 interactors

Proteomic databases

PRIDEiP10201

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

OrthoDBiVOG0900002R

Family and domain databases

HAMAPiMF_04017 HSV_CVC1, 1 hit
InterProiView protein in InterPro
IPR007640 UL17-like
PfamiView protein in Pfam
PF04559 Herpes_UL17, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCVC1_HHV11
AccessioniPrimary (citable) accession number: P10201
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: October 10, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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