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Entry version 201 (29 Sep 2021)
Sequence version 1 (01 Jul 1989)
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Protein

Homeobox protein cut

Gene

ct

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulator of cell fate decisions in multiple lineages. Specifically, functions as a determination factor that specifies sensory organ identity in precursor cells. Probably also involved in cell type specification of Malpighian tubules. In absence of cut gene external sensory organs are transformed into chordotonal organs.

Miscellaneous

Asn-1791 may participate in regulating DNA-binding activity by promoting homo- and heterodimerization.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi877 – 964CUT 1PROSITE-ProRule annotationAdd BLAST88
DNA bindingi1330 – 1417CUT 2PROSITE-ProRule annotationAdd BLAST88
DNA bindingi1608 – 1695CUT 3PROSITE-ProRule annotationAdd BLAST88
DNA bindingi1745 – 1804HomeoboxPROSITE-ProRule annotationAdd BLAST60

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Homeobox protein cut
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ct
ORF Names:CG11387
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0004198, ct

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:FBgn0004198

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002023901 – 2175Homeobox protein cutAdd BLAST2175

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1940Phosphoserine1 Publication1
Modified residuei1944Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P10180

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P10180

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in many cells in the central nervous system, all external sensory organs, some peripheral neurons, and in the non-neural cells of the spiracles and the Malpighian tubules.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Cell-specific pattern of expression. Broadly expressed during embryonic development.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0004198, Expressed in central nervous system and 46 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P10180, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P10180, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
69119, 104 interactors

Database of interacting proteins

More...
DIPi
DIP-19788N

Protein interaction database and analysis system

More...
IntActi
P10180, 10 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0113105

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P10180

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni139 – 170DisorderedSequence analysisAdd BLAST32
Regioni249 – 432DisorderedSequence analysisAdd BLAST184
Regioni503 – 600DisorderedSequence analysisAdd BLAST98
Regioni656 – 765DisorderedSequence analysisAdd BLAST110
Regioni1001 – 1083DisorderedSequence analysisAdd BLAST83
Regioni1197 – 1289DisorderedSequence analysisAdd BLAST93
Regioni1507 – 1588DisorderedSequence analysisAdd BLAST82
Regioni1695 – 1747DisorderedSequence analysisAdd BLAST53
Regioni1803 – 1826DisorderedSequence analysisAdd BLAST24
Regioni1922 – 1955DisorderedSequence analysisAdd BLAST34
Regioni2069 – 2097DisorderedSequence analysisAdd BLAST29
Regioni2113 – 2175DisorderedSequence analysisAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili265 – 343Sequence analysisAdd BLAST79
Coiled coili433 – 499Sequence analysisAdd BLAST67
Coiled coili1056 – 1161Sequence analysisAdd BLAST106
Coiled coili1463 – 1522Sequence analysisAdd BLAST60

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi249 – 266Polar residuesSequence analysisAdd BLAST18
Compositional biasi271 – 298Acidic residuesSequence analysisAdd BLAST28
Compositional biasi299 – 326Polar residuesSequence analysisAdd BLAST28
Compositional biasi340 – 414Polar residuesSequence analysisAdd BLAST75
Compositional biasi503 – 521Polar residuesSequence analysisAdd BLAST19
Compositional biasi545 – 560Acidic residuesSequence analysisAdd BLAST16
Compositional biasi569 – 585Acidic residuesSequence analysisAdd BLAST17
Compositional biasi676 – 694Basic residuesSequence analysisAdd BLAST19
Compositional biasi695 – 710Polar residuesSequence analysisAdd BLAST16
Compositional biasi715 – 729Basic residuesSequence analysisAdd BLAST15
Compositional biasi734 – 765Polar residuesSequence analysisAdd BLAST32
Compositional biasi1008 – 1028Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi1029 – 1058Polar residuesSequence analysisAdd BLAST30
Compositional biasi1059 – 1083Basic and acidic residuesSequence analysisAdd BLAST25
Compositional biasi1209 – 1224Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi1234 – 1251Pro residuesSequence analysisAdd BLAST18
Compositional biasi1257 – 1289Polar residuesSequence analysisAdd BLAST33
Compositional biasi1507 – 1527Polar residuesSequence analysisAdd BLAST21
Compositional biasi1569 – 1583Polar residuesSequence analysisAdd BLAST15
Compositional biasi1706 – 1734Polar residuesSequence analysisAdd BLAST29
Compositional biasi1922 – 1936Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi2138 – 2165Polar residuesSequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CUT homeobox family.Curated

Keywords - Domaini

Coiled coil, Homeobox, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2252, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000172657

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001394_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P10180

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00086, homeodomain, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.260.40, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003350, CUT_dom
IPR009057, Homeobox-like_sf
IPR017970, Homeobox_CS
IPR001356, Homeobox_dom
IPR010982, Lambda_DNA-bd_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02376, CUT, 3 hits
PF00046, Homeodomain, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01109, CUT, 3 hits
SM00389, HOX, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 1 hit
SSF47413, SSF47413, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51042, CUT, 3 hits
PS00027, HOMEOBOX_1, 1 hit
PS50071, HOMEOBOX_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P10180-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQPTLPQAAG TADMDLTAVQ SINDWFFKKE QIYLLAQFWQ QRATLAEKEV
60 70 80 90 100
NTLKEQLSTG NPDSNLNSEN SDTAAAAATA AAVAAVVAGA TATNDIEDEQ
110 120 130 140 150
QQQLQQTASG GILESDSDKL LNSSIVAAAI TLQQQNGSNL LANTNTPSPS
160 170 180 190 200
PPLLSAEQQQ QLQSSLQQSG GVGGACLNPK LFFNHAQQMM MMEAAAAAAA
210 220 230 240 250
AALQQQQQQQ SPLHSPANEV AIPTEQPAAT VATGAAAAAA AAATPIATGN
260 270 280 290 300
VKSGSTTSNA NHTNSNNSHQ DEEELDDEEE DEEEDEDEDD EEENASMQSN
310 320 330 340 350
ADDMELDAQQ ETRTEPSATT QQQHQQQDTE DLEENKDAGE ASLNVSNNHN
360 370 380 390 400
TTDSNNSCSR KNNNGGNESE QHVASSAEDD DCANNNTNTS NNNNTSNTAT
410 420 430 440 450
SNTNNNNNNN SSSGNSEKRK KKNNNNNNGQ PAVLLAAKDK EIKALLDELQ
460 470 480 490 500
RLRAQEQTHL VQIQRLEEHL EVKRQHIIRL EARLDKQQIN EALAEATALS
510 520 530 540 550
AAASTNNNNN SQSSDNNKKL NTAAERPMDA SSNADLPEST KAPVPAEDDE
560 570 580 590 600
EDEDQAMLVD SEEAEDKPED SHHDDDEDED EDREAVNATT TDSNELKIKK
610 620 630 640 650
EQHSPLDLNV LSPNSAIAAA AAAAAAAACA NDPNKFQALL IERTKALAAE
660 670 680 690 700
ALKNGASDAL SEDAHHQQQQ HHQQQHQHQQ QHHQQQHLHQ QHHHHLQQQP
710 720 730 740 750
NSGSNSNPAS NDHHHGHHLH GHGLLHPSSA HHLHHQTTES NSNSSTPTAA
760 770 780 790 800
GNNNGSNNSS SNTNANSTAQ LAASLASTLN GTKSLMQEDS NGLAAVAMAA
810 820 830 840 850
HAQHAAALGP GFLPGLPAFQ FAAAQVAAGG DGRGHYRFAD SELQLPPGAS
860 870 880 890 900
MAGRLGESLI PKGDPMEAKL QEMLRYNMDK YANQALDTLH ISRRVRELLS
910 920 930 940 950
VHNIGQRLFA KYILGLSQGT VSELLSKPKP WDKLTEKGRD SYRKMHAWAC
960 970 980 990 1000
DDNAVMLLKS LIPKKDSGLP QYAGRGAGGA GGDDSMSEDR IAHILSEASS
1010 1020 1030 1040 1050
LMKQSSVAQH REQERRSHGG EDSHSNEDSK SPPQSCTSPF FKVENQLKQH
1060 1070 1080 1090 1100
QHLNPEQAAA QQREREREQR EREQQQRLRH DDQDKMARLY QELIARTPRE
1110 1120 1130 1140 1150
TAFPSFLFSP SLFGGAAGMP GAASNAFPAM ADENMRHVFE REIAKLQQHQ
1160 1170 1180 1190 1200
QQQQAAQAQA QFPNFSSLMA LQQQVLNGAQ DLSLAAAAAK DIKLNGQRSS
1210 1220 1230 1240 1250
LEHSAGSSSC SKDGERDDAY PSSLHGRKSE GGGTPAPPAP PSGPGTGAGA
1260 1270 1280 1290 1300
PPTAAPPTGG ASSNSAAPSP LSNSILPPAL SSQGEEFAAT ASPLQRMASI
1310 1320 1330 1340 1350
TNSLITQPPV TPHHSTPQRP TKAVLPPITQ QQFDMFNNLN TEDIVRRVKE
1360 1370 1380 1390 1400
ALSQYSISQR LFGESVLGLS QGSVSDLLAR PKPWHMLTQK GREPFIRMKM
1410 1420 1430 1440 1450
FLEDENAVHK LVASQYKIAP EKLMRTGSYS GSPQMPQGLA SKMQAASLPM
1460 1470 1480 1490 1500
QKMMSELKLQ EPAQAQHLMQ QMQAAAMSAA MQQQQVAQAQ QQAQQAQQAQ
1510 1520 1530 1540 1550
QHLQQQAQQH LQQQQHLAQQ QHPHQQHHQA AAAAAALHHQ SMLLTSPGLP
1560 1570 1580 1590 1600
PQHAISLPPS AGGAQPGGPG GNQGSSNPSN SEKKPMLMPV HGTNAMRSLH
1610 1620 1630 1640 1650
QHMSPTVYEM AALTQDLDTH DITTKIKEAL LANNIGQKIF GEAVLGLSQG
1660 1670 1680 1690 1700
SVSELLSKPK PWHMLSIKGR EPFIRMQLWL SDANNVERLQ LLKNERREAS
1710 1720 1730 1740 1750
KRRRSTGPNQ QDNSSDTSSN DTNDFYTSSP GPGSVGSGVG GAPPSKKQRV
1760 1770 1780 1790 1800
LFSEEQKEAL RLAFALDPYP NVGTIEFLAN ELGLATRTIT NWFHNHRMRL
1810 1820 1830 1840 1850
KQQVPHGPAG QDNPIPSRES TSATPFDPVQ FRILLQQRLL ELHKERMGMS
1860 1870 1880 1890 1900
GAPIPYPPYF AAAAILGRSL AGIPGAAAAA GAAAAAAAVG ASGGDELQAL
1910 1920 1930 1940 1950
NQAFKEQMSG LDLSMPTLKR ERSDDYQDDL ELEGGGHNLS DNESLEGQEP
1960 1970 1980 1990 2000
EDKTTDYEKV LHKSALAAAA AYMSNAVRSS RRKPAAPQWV NPAGAVTNPS
2010 2020 2030 2040 2050
AVVAAVAAAA AAAADNERII NGVCVMQASE YGRDDTDSNK PTDGGNDSDH
2060 2070 2080 2090 2100
EHAQLEIDQR FMEPEVHIKQ EEDDDEEQSG SVNLDNEDNA TSEQKLKVIN
2110 2120 2130 2140 2150
EEKLRMVRVR RLSSTGGGSS EEMPAPLAPP PPPPAASSSI VSGESTTSSS
2160 2170
SSSNTSSSTP AVTTAAATAA AGWNY
Length:2,175
Mass (Da):233,629
Last modified:July 1, 1989 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i08BF80C4861BD0AB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PGW9M9PGW9_DROME
Homeobox protein cut-like
ct BcDNA:GH10590, CT, Ct, CUT, Cut
2,174Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9NEA5M9NEA5_DROME
Homeobox protein cut-like
ct BcDNA:GH10590, CT, Ct, CUT, Cut
2,165Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X07985 mRNA Translation: CAA30794.1
AE014298 Genomic DNA Translation: AAF46264.2

Protein sequence database of the Protein Information Resource

More...
PIRi
S03170

NCBI Reference Sequences

More...
RefSeqi
NP_524764.1, NM_080025.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0071068; FBpp0071026; FBgn0004198

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
44540

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG11387

UCSC genome browser

More...
UCSCi
CG11387-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07985 mRNA Translation: CAA30794.1
AE014298 Genomic DNA Translation: AAF46264.2
PIRiS03170
RefSeqiNP_524764.1, NM_080025.2

3D structure databases

SMRiP10180
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi69119, 104 interactors
DIPiDIP-19788N
IntActiP10180, 10 interactors
STRINGi7227.FBpp0113105

PTM databases

iPTMnetiP10180

Proteomic databases

PaxDbiP10180

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
44540

Genome annotation databases

EnsemblMetazoaiFBtr0071068; FBpp0071026; FBgn0004198
GeneIDi44540
KEGGidme:Dmel_CG11387
UCSCiCG11387-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
44540
FlyBaseiFBgn0004198, ct
VEuPathDBiVectorBase:FBgn0004198

Phylogenomic databases

eggNOGiKOG2252, Eukaryota
GeneTreeiENSGT00940000172657
HOGENOMiCLU_001394_1_0_1
InParanoidiP10180

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
44540, 1 hit in 3 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ct, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
44540

Protein Ontology

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PROi
PR:P10180

Gene expression databases

BgeeiFBgn0004198, Expressed in central nervous system and 46 other tissues
ExpressionAtlasiP10180, baseline and differential
GenevisibleiP10180, DM

Family and domain databases

CDDicd00086, homeodomain, 1 hit
Gene3Di1.10.260.40, 3 hits
InterProiView protein in InterPro
IPR003350, CUT_dom
IPR009057, Homeobox-like_sf
IPR017970, Homeobox_CS
IPR001356, Homeobox_dom
IPR010982, Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376, CUT, 3 hits
PF00046, Homeodomain, 1 hit
SMARTiView protein in SMART
SM01109, CUT, 3 hits
SM00389, HOX, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
SSF47413, SSF47413, 3 hits
PROSITEiView protein in PROSITE
PS51042, CUT, 3 hits
PS00027, HOMEOBOX_1, 1 hit
PS50071, HOMEOBOX_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCUT_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P10180
Secondary accession number(s): Q9W3Q6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: September 29, 2021
This is version 201 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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