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Protein

Protein C-ets-2

Gene

ETS2

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable transcription factor.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi373 – 453ETSPROSITE-ProRule annotationAdd BLAST81

GO - Molecular functioni

GO - Biological processi

  • branching involved in blood vessel morphogenesis Source: DFLAT
  • cell differentiation Source: GO_Central
  • coronary artery morphogenesis Source: DFLAT
  • regulation of transcription by RNA polymerase II Source: GO_Central
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-GGA-2559585 Oncogene Induced Senescence

Names & Taxonomyi

Protein namesi
Recommended name:
Protein C-ets-2
Gene namesi
Name:ETS2
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Keywords - Diseasei

Proto-oncogene

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002040761 – 479Protein C-ets-2Add BLAST479

Proteomic databases

PaxDbiP10157

Expressioni

Gene expression databases

BgeeiENSGALG00000016059

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000025826

Structurei

3D structure databases

ProteinModelPortaliP10157
SMRiP10157
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 173PNTPROSITE-ProRule annotationAdd BLAST86

Sequence similaritiesi

Belongs to the ETS family.Curated

Phylogenomic databases

eggNOGiKOG3806 Eukaryota
ENOG410Z0ZF LUCA
GeneTreeiENSGT00760000118907
HOGENOMiHOG000285953
HOVERGENiHBG003088
InParanoidiP10157
KOiK21932
OMAiFGMNGQV
OrthoDBiEOG091G0HJF
PhylomeDBiP10157

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000418 Ets_dom
IPR003118 Pointed_dom
IPR013761 SAM/pointed_sf
IPR016311 Transform_prot_C-ets
IPR027276 Transform_prot_C-ets-2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00178 Ets, 1 hit
PF02198 SAM_PNT, 1 hit
PIRSFiPIRSF501032 C-ets-2, 1 hit
PIRSF001698 Transforming_factor_C-ets, 1 hit
PRINTSiPR00454 ETSDOMAIN
SMARTiView protein in SMART
SM00413 ETS, 1 hit
SM00251 SAM_PNT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS00345 ETS_DOMAIN_1, 1 hit
PS00346 ETS_DOMAIN_2, 1 hit
PS50061 ETS_DOMAIN_3, 1 hit
PS51433 PNT, 1 hit

Sequencei

Sequence statusi: Complete.

P10157-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEFAIRNMD QVAPVSNMYR GMLKRQPAFD TFDSSNSLFA GYFLSLNEDQ
60 70 80 90 100
TLQEVPTGFD STSYESNNCE LPLLTPCSKA VMSQALKDTF SGFTKEQCRL
110 120 130 140 150
GIPNNPWLWT EQHVCQWLAW ATNEFSLANV NIHQFLMSGQ DLCNLGKERF
160 170 180 190 200
LELAPDYVGD ILWEHLEQMI KDSQEKTQDQ YVESSHLTSV PHWVNNNSLT
210 220 230 240 250
VNVDQTPYGI QMPGYPKALS YPKPNLLSDI CQTSTGPNLL SPEQDFSLFP
260 270 280 290 300
KTQVDAVSVN YCTVNQDFTR SNLNLLIDNS GKLREHESSE SGAESYESSD
310 320 330 340 350
SMLQSWNSQS SLVDLQRVPS YESFEDDCSQ SLCMSKPTMS FKDYIQDRSD
360 370 380 390 400
PVEQGKPVIP AAILAGFTGS GPIQLWQFLL ELLTDKSCQS FISWTGDGWE
410 420 430 440 450
FKLADPDEVA RRWGRRKNKP KMNYEKLSRG LRYYYDKNII HKTSGKRYVY
460 470
RFVCDLQNLL GYTAEELHAM LGVQPDTED
Length:479
Mass (Da):54,540
Last modified:July 1, 1989 - v1
Checksum:i91BCD5206972E867
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07202 mRNA Translation: CAA30178.1
PIRiS00386 TVCHE2
RefSeqiNP_990643.1, NM_205312.1
UniGeneiGga.4768

Genome annotation databases

EnsembliENSGALT00000025873; ENSGALP00000025826; ENSGALG00000016059
GeneIDi396250
KEGGigga:396250

Similar proteinsi

Entry informationi

Entry nameiETS2_CHICK
AccessioniPrimary (citable) accession number: P10157
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: May 23, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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