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Protein

Neuroblastoma breakpoint family member 9

Gene

NBPF9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neuroblastoma breakpoint family member 9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NBPF9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:31991 NBPF9

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
613999 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P0DPF3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000269713

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002880441 – 1111Neuroblastoma breakpoint family member 9Add BLAST1111

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P0DPF3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in a neuroblastoma cell line.1 Publication

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA038748
HPA042595
HPA043105
HPA043692
HPA044023
HPA046971
HPA058050

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini165 – 259NBPF 1PROSITE-ProRule annotationAdd BLAST95
Domaini436 – 528NBPF 2PROSITE-ProRule annotationAdd BLAST93
Domaini529 – 600NBPF 3PROSITE-ProRule annotationAdd BLAST72
Domaini601 – 692NBPF 4PROSITE-ProRule annotationAdd BLAST92
Domaini695 – 750NBPF 5PROSITE-ProRule annotationAdd BLAST56
Domaini751 – 843NBPF 6PROSITE-ProRule annotationAdd BLAST93
Domaini844 – 919NBPF 7PROSITE-ProRule annotationAdd BLAST76
Domaini920 – 1012NBPF 8PROSITE-ProRule annotationAdd BLAST93
Domaini1013 – 1111NBPF 9PROSITE-ProRule annotationAdd BLAST99

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili70 – 130Sequence analysisAdd BLAST61
Coiled coili341 – 401Sequence analysisAdd BLAST61

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NBPF family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00420000029746

Database of Orthologous Groups

More...
OrthoDBi
372685at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010630 Olduvai_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06758 Olduvai, 9 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01148 DUF1220, 9 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51316 NBPF, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P0DPF3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVVSAGPWSS EKAEMNILEI NEKLRPQLAE NKQQFGNLKE RCFLTQLAGF
60 70 80 90 100
LANRQKKYKY EECKDLIKFM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH
110 120 130 140 150
SQERELTQLK EKLREGRDAS RSLNEHLQAL LTPDEPDKSQ GQDLQEQLAE
160 170 180 190 200
GCRLAQHLVQ KLSPENDEDE DEDVQVEEDE KVLESSAPRE VQKAEESKVA
210 220 230 240 250
EDSLEECAIT CSNSHGPCDS NQPHKNIKIT FEEDEVNSTL VVDRESSHDE
260 270 280 290 300
CQDALNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLRPQLA
310 320 330 340 350
EKKQQFRNLK EKCFLTQLAG FLANQQNKYK YEECKDLIKF MLRNERQFKE
360 370 380 390 400
EKLAEQLKQA EELRQYKVLV HAQERELTQL REKLREGRDA SRSLNEHLQA
410 420 430 440 450
LLTPDEPDKS QGQDLQEQLA EGCRLAQHLV QKLSPENDND DDEDVQIEVA
460 470 480 490 500
EKVQKSSAPR EMQKAEEKEV PEDSLEECAI TYSNSHGPYD SNQPHRKTKI
510 520 530 540 550
TFEEDKVDST LIGSSSHVER EDAVHIIPEN ESDDEEEEEK GPVSPRNLQE
560 570 580 590 600
SEEEEVPQES WDEGYSTPSI PPEMLASYKS YSSTFHSLEE QQVCMAVDIG
610 620 630 640 650
RHRWDQVKKE DQEATGPRLS RELLDEKGPE VLQDSLDRCY STPSGCLELT
660 670 680 690 700
DSCQPYRSAF YVLEQQRVGL AVDMDEIEKY QEVEEDQDPS CPRLSRELLD
710 720 730 740 750
EKEPEVLQDS LGRWYSTPSG YLELPDLGQP YSSAVYSLEE QYLGLALDLD
760 770 780 790 800
RIKKDQEEEE DQGPPCPRLS RELLEVVEPE VLQDSLDRCY STPSSCLEQP
810 820 830 840 850
DSCQPYGSSF YALEEKHVGF SLDVGEIEKK GKGKKRRGRR SKKKRRRGRK
860 870 880 890 900
EGEENQNPPC PRLSRELLDE KEPEVLQDSL DRCYSTPSGY LELPDLGQPY
910 920 930 940 950
SSAVYSLEEQ YLGLALDVDR IKKDQEEEED QGPPCPRLSR ELLEVVEPEV
960 970 980 990 1000
LQDSLDRCYS TPSSCLEQPD SCQPYGSSFY ALEEKHVGFS LDVGEIEKKG
1010 1020 1030 1040 1050
KGKKRRGRRS KKERRRGRKE GEEDQNPPCP RLNGVLMEVE EPEVLQDSLD
1060 1070 1080 1090 1100
GCYSTPSMYF ELPDSFQHYR SVFYSFEEQH ISFALYVDNR FFTLTVTSLH
1110
LVFQMEVIFP Q
Note: No experimental confirmation available. Derived from EST data.
Length:1,111
Mass (Da):127,756
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i45ECF606F97DB02E
GO
Isoform 2 (identifier: P0DPF3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     765-933: Missing.

Show »
Length:942
Mass (Da):108,436
Checksum:i36F219C4C792FAC4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WVG0A0A087WVG0_HUMAN
Neuroblastoma breakpoint family mem...
NBPF9
867Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X0Y3A0A087X0Y3_HUMAN
Neuroblastoma breakpoint family mem...
NBPF9
299Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WYQ9A0A087WYQ9_HUMAN
Neuroblastoma breakpoint family mem...
NBPF9
942Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WZE1A0A087WZE1_HUMAN
Neuroblastoma breakpoint family mem...
NBPF9
981Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti186S → P in AAX85113 (PubMed:16079250).Curated1
Sequence conflicti200A → T in AAX85113 (PubMed:16079250).Curated1
Sequence conflicti442D → N in AAX85113 (PubMed:16079250).Curated1
Sequence conflicti447I → V in AAX85113 (PubMed:16079250).Curated1
Sequence conflicti637D → Y in AAX85113 (PubMed:16079250).Curated1
Sequence conflicti722L → P in AAX85113 (PubMed:16079250).Curated1
Sequence conflicti972C → W in AAX85113 (PubMed:16079250).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_059364765 – 933Missing in isoform 2. 1 PublicationAdd BLAST169

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY894574 mRNA Translation: AAX85113.1
AC239804 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS72895.1 [P0DPF3-2]
CCDS72896.1 [P0DPF3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001032764.2, NM_001037675.3 [P0DPF3-2]
NP_001264373.1, NM_001277444.1 [P0DPF3-1]
XP_006711380.1, XM_006711317.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.445080
Hs.714127

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000584027; ENSP00000463665; ENSG00000269713 [P0DPF3-1]
ENST00000610300; ENSP00000481471; ENSG00000269713 [P0DPF3-2]
ENST00000613595; ENSP00000483900; ENSG00000269713 [P0DPF3-2]
ENST00000615421; ENSP00000477979; ENSG00000269713 [P0DPF3-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
400818

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:400818

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY894574 mRNA Translation: AAX85113.1
AC239804 Genomic DNA No translation available.
CCDSiCCDS72895.1 [P0DPF3-2]
CCDS72896.1 [P0DPF3-1]
RefSeqiNP_001032764.2, NM_001037675.3 [P0DPF3-2]
NP_001264373.1, NM_001277444.1 [P0DPF3-1]
XP_006711380.1, XM_006711317.2
UniGeneiHs.445080
Hs.714127

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Proteomic databases

jPOSTiP0DPF3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000584027; ENSP00000463665; ENSG00000269713 [P0DPF3-1]
ENST00000610300; ENSP00000481471; ENSG00000269713 [P0DPF3-2]
ENST00000613595; ENSP00000483900; ENSG00000269713 [P0DPF3-2]
ENST00000615421; ENSP00000477979; ENSG00000269713 [P0DPF3-1]
GeneIDi400818
KEGGihsa:400818

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
400818

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NBPF9
HGNCiHGNC:31991 NBPF9
HPAiHPA038748
HPA042595
HPA043105
HPA043692
HPA044023
HPA046971
HPA058050
MIMi613999 gene
neXtProtiNX_P0DPF3
OpenTargetsiENSG00000269713

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00420000029746
OrthoDBi372685at2759

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P0DPF3

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR010630 Olduvai_dom
PfamiView protein in Pfam
PF06758 Olduvai, 9 hits
SMARTiView protein in SMART
SM01148 DUF1220, 9 hits
PROSITEiView protein in PROSITE
PS51316 NBPF, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNBPF9_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0DPF3
Secondary accession number(s): A0A075B761
, A0A087WVA0, A0A087WY26, Q3BBV1, Q3BBW0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 28, 2018
Last sequence update: March 28, 2018
Last modified: January 16, 2019
This is version 10 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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