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Protein

Putative protein YbeM

Gene

ybeM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Pseudogene resulting from a nucleotide deletion that introduces a premature stop codon at position 66. This is the C-terminal fragment. The intact protein (AC A0A140NCB4) hydrolyzes deaminated glutathione (dGSH, 2-oxoglutaramate) to alpha-ketoglutarate (alpha-KG) and cysteinylglycine, has less activity against alpha-ketoglutaramate (a-KGM) and no activity on glutathione or L-glutamine (By similarity). May function as a metabolite repair enzyme (By similarity).By similarity

Caution

Could be the product of a pseudogene.Curated

GO - Biological processi

Enzyme and pathway databases

BioCyciEcoCyc:G6348-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein YbeM
Gene namesi
Name:ybeM
Ordered Locus Names:b4581, JW0621
ORF Names:b0626
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13162 ybeM

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002132581 – 187Putative protein YbeMAdd BLAST187

Structurei

3D structure databases

SMRiP0DP64
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 163CN hydrolasePROSITE-ProRule annotationAdd BLAST163

Sequence similaritiesi

Phylogenomic databases

KOiK11206

Family and domain databases

Gene3Di3.60.110.10, 1 hit
InterProiView protein in InterPro
IPR003010 C-N_Hydrolase
IPR036526 C-N_Hydrolase_sf
IPR001110 UPF0012_CS
PfamiView protein in Pfam
PF00795 CN_hydrolase, 1 hit
SUPFAMiSSF56317 SSF56317, 1 hit
PROSITEiView protein in PROSITE
PS50263 CN_HYDROLASE, 1 hit
PS01227 UPF0012, 1 hit

Sequencei

Sequence statusi: Complete.

P0DP64-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTTILTIHV PSTPGRAWNM LVALQAGNIV ARYAKLHLYD AFAIQESRRV
60 70 80 90 100
DAGNEIAPLL EVEGMKVGLM TCYDLRFPEL ALAQALQGAE ILVLPAAWVR
110 120 130 140 150
GPLKEHHWST LLAARALDTT CYMVAAGECG NKNIGQSRII DPFGVTIAAA
160 170 180
SEMPALIMAE VTPERVRQVR AQLPVLNNRR FAPPQLL
Length:187
Mass (Da):20,482
Last modified:July 5, 2017 - v1
Checksum:i18B5DD09806F9DC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA Translation: AAB40826.1
U00096 Genomic DNA No translation available.
AP009048 Genomic DNA Translation: BAA35269.1
U38811 Genomic DNA No translation available.
PIRiH64796
RefSeqiWP_001310635.1, NZ_LN832404.1

Genome annotation databases

KEGGiecj:JW0621

Entry informationi

Entry nameiYBEM_ECOLI
AccessioniPrimary (citable) accession number: P0DP64
Secondary accession number(s): P39874, P77104, P77192
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2017
Last sequence update: July 5, 2017
Last modified: June 20, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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