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Protein

Conantokin-Gm

Gene
N/A
Organism
Conus gloriamaris (Glory-of-the-Seas cone)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors.By similarity

Miscellaneous

The mature peptide does not contain cysteine residue.Curated

GO - Molecular functioni

Keywordsi

Molecular functionIon channel impairing toxin, Ionotropic glutamate receptor inhibitor, Neurotoxin, Postsynaptic neurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conantokin-Gm1 Publication
Short name:
Con-Gm1 Publication
OrganismiConus gloriamaris (Glory-of-the-Seas cone)
Taxonomic identifieri37336 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaNeogastropodaConoideaConidaeConusCylinder

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00004393731 – 18Conantokin-GmAdd BLAST18

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei44-carboxyglutamate1 Publication1
Modified residuei94-carboxyglutamate1 Publication1
Modified residuei134-carboxyglutamate1 Publication1

Keywords - PTMi

Gamma-carboxyglutamic acid

Expressioni

Tissue specificityi

Expressed by the venom duct.Curated

Sequencei

Sequence statusi: Complete.

Length:18
Mass (Da):2,084
Last modified:April 12, 2017 - v1
Checksum:i436FF61E9EBACB5B
GO

Similar proteinsi

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiCKG_CONGL
AccessioniPrimary (citable) accession number: P0DOZ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2017
Last sequence update: April 12, 2017
Last modified: September 12, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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