Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Conantokin-Ca2

Gene
N/A
Organism
Conus caracteristicus (Characteristic cone)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors.By similarity

Miscellaneous

The mature peptide does not contain cysteine residue.Curated

GO - Molecular functioni

Keywordsi

Molecular functionIon channel impairing toxin, Ionotropic glutamate receptor inhibitor, Neurotoxin, Postsynaptic neurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conantokin-Ca21 Publication
Short name:
Con-Ca21 Publication
OrganismiConus caracteristicus (Characteristic cone)
Taxonomic identifieri89440 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaNeogastropodaConoideaConidaeConus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00004393721 – 17Conantokin-Ca2Add BLAST17

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei34-carboxyglutamate1 Publication1
Modified residuei44-carboxyglutamate1 Publication1
Modified residuei64-carboxyglutamate1 Publication1
Modified residuei94-carboxyglutamate1 Publication1
Modified residuei134-carboxyglutamate1 Publication1

Keywords - PTMi

Gamma-carboxyglutamic acid

Expressioni

Tissue specificityi

Expressed by the venom duct.Curated

Sequencei

Sequence statusi: Complete.

Length:17
Mass (Da):2,023
Last modified:April 12, 2017 - v1
Checksum:iB4B6146F7DCB568E
GO

Similar proteinsi

Entry informationi

Entry nameiCKC_CONCB
AccessioniPrimary (citable) accession number: P0DOZ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2017
Last sequence update: April 12, 2017
Last modified: September 12, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again