rplF

Functionⁱ

This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

GO - Molecular functionⁱ

rRNA binding Source: UniProtKB-KW
structural constituent of ribosome Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

translation Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Molecular function

Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 50S ribosomal protein L6UniRule annotation
Gene namesⁱ	Name:rplFUniRule annotation Ordered Locus Names:TTHA1677
Organismⁱ	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifierⁱ	300852 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus › Thermus thermophilus
Proteomesⁱ	UP000000532 Componentⁱ: Chromosome

Subcellular locationⁱ

GO - Cellular componentⁱ

ribosome Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		Removed1 Publication
ChainⁱPRO_0000131072	2 – 180	50S ribosomal protein L6Add BLAST		179

Interactionⁱ

Subunit structureⁱ

Part of the 50S ribosomal subunit.

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	21 – 28	Combined sources	8
Beta strandⁱ	31 – 36	Combined sources	6
Beta strandⁱ	47 – 49	Combined sources	3
Helixⁱ	59 – 79	Combined sources	21
Beta strandⁱ	86 – 93	Combined sources	8
Beta strandⁱ	95 – 99	Combined sources	5
Beta strandⁱ	102 – 106	Combined sources	5
Beta strandⁱ	108 – 111	Combined sources	4
Beta strandⁱ	113 – 115	Combined sources	3
Beta strandⁱ	121 – 124	Combined sources	4
Beta strandⁱ	126 – 138	Combined sources	13
Helixⁱ	139 – 150	Combined sources	12
Beta strandⁱ	161 – 163	Combined sources	3

Show more details

3D structure databases

SMRⁱ	P0DOY8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the universal ribosomal protein uL6 family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4108R5J Bacteria COG0097 LUCA
HOGENOMⁱ	HOG000039903
KEGG Orthology (KO) More...KOⁱ	K02933
OMAⁱ	INNMVVG
PhylomeDBⁱ	Q5SHQ3

Family and domain databases

Gene3Dⁱ	3.90.930.12, 2 hits
HAMAPⁱ	MF_01365_B Ribosomal_L6_B, 1 hit
InterProⁱ	View protein in InterPro IPR000702 Ribosomal_L6 IPR020040 Ribosomal_L6_a/b-dom IPR036789 Ribosomal_L6_a/b-dom_sf IPR019906 Ribosomal_L6_bac-type
PANTHERⁱ	PTHR11655 PTHR11655, 1 hit PTHR11655:SF14 PTHR11655:SF14, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00347 Ribosomal_L6, 2 hits
PIRSFⁱ	PIRSF002162 Ribosomal_L6, 1 hit
PRINTSⁱ	PR00059 RIBOSOMALL6
SUPFAMⁱ	SSF56053 SSF56053, 2 hits
TIGRFAMsⁱ	TIGR03654 L6_bact, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P0DOY8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSRIGRLPIP VPKGVSVEVA PGRVKVKGPK GELEVPVSPE MRVVVEEGVV 
        60         70         80         90        100
RVERPSDERR HKSLHGLTRT LIANAVKGVS EGYSKELLIK GIGYRARLVG 
       110        120        130        140        150
RALELTVGFS HPVVVEPPEG ITFEVPEPTR VRVSGIDKQK VGQVAANIRA 
       160        170        180
IRKPSAYHEK GIYYAGEPVR LKPGKAGAKK

Length:180

Mass (Da):19,532

Last modified:March 15, 2017 - v1

Checksum:ⁱ1913833C0C30E95D

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	19 – 20	VA → AV AA sequence (PubMed:11154066).Curated	2
Sequence conflictⁱ	25	K → L AA sequence (PubMed:11154066).Curated	1
Sequence conflictⁱ	27	K → Y AA sequence (PubMed:11154066).Curated	1

Mass spectrometryⁱ

Molecular mass is 19401 Da from positions 2 - 180. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AP008226 Genomic DNA Translation: BAD71500.1
PIRⁱ	S15442
NCBI Reference Sequences More...RefSeqⁱ	WP_011173704.1, NC_006461.1 YP_144943.1, NC_006461.1

Genome annotation databases

GeneIDⁱ	3169807
KEGGⁱ	ttj:TTHA1677

Protein	Similar proteins		Species	Score	Length	Source
P0DOY8	50S ribosomal protein L6	)	THET2		180	UniRef100_Q72I19
50S ribosomal protein L6	)	THETH		180
50S ribosomal protein L6		Thermus thermophilus JL-18		180
UPI00062CAFC2		THET8		174
UPI000CF5D9FC		THET8		173
+6

Protein	Similar proteins		Species	Score	Length	Source
P0DOY8	50S ribosomal protein L6	)	THET2		180	UniRef90_Q72I19
50S ribosomal protein L6	)	THETH		180
50S ribosomal protein L6		THEAQ		180
50S ribosomal protein L6		Thermus thermophilus JL-18		180
50S ribosomal protein L6		Thermus aquaticus Y51MC23		180
+13

Protein	Similar proteins		Species	Score	Length	Source
P0DOY8	50S ribosomal protein L6	)	DEIRA		185	UniRef50_Q9RSL3
50S ribosomal protein L6		CLOP1		179
50S ribosomal protein L6		CLOPE		179
50S ribosomal protein L6		CLOPS		179
50S ribosomal protein L6		DESRM		182
+1595

Entry informationⁱ

Entry nameⁱ	RL6_THET8
Accessionⁱ	P0DOY8Primary (citable) accession number: P0DOY8 Secondary accession number(s): Q5SHQ3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	March 15, 2017
	Last sequence update:	March 15, 2017
	Last modified:	September 12, 2018
	This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

UniProtKB - P0DOY8 (RL6_THET8)

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50S ribosomal protein L6

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Molecule processing

Interactionⁱ

Subunit structureⁱ

Structureⁱ

Secondary structure

3D structure databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Mass spectrometryⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

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UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P0DOY8 (RL6_THET8)

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50S ribosomal protein L6

rplF

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

<p>This subsection of the ‘Sequence’ section reports information derived from mass spectrometry experiments done on the entire protein or on biologically active derived peptide(s).<p><a href='/help/mass_spectrometry' target='_top'>More...</a></p>Mass spectrometryi

Sequence databases

Genome annotation databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Mass spectrometryⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ