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Entry version 24 (08 May 2019)
Sequence version 1 (27 May 2015)
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Protein

Cancer/testis antigen family 45 member A10

Gene

CT45A10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • snRNA 3'-end processing Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cancer/testis antigen family 45 member A10Imported
Alternative name(s):
Cancer/testis antigen 45A10Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CT45A10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:51263 CT45A10

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P0DMU9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000269586

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CT45A10

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004330321 – 189Cancer/testis antigen family 45 member A10Add BLAST189

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P0DMU9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P0DMU9

PeptideAtlas

More...
PeptideAtlasi
P0DMU9

PRoteomics IDEntifications database

More...
PRIDEi
P0DMU9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P0DMU9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P0DMU9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000269586 Expressed in 33 organ(s), highest expression level in testis

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044735
HPA044757
HPA046872
HPA046987

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
SDCBPO005604EBI-12153495,EBI-727004

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
P0DMU9, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000484601

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P0DMU9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CT45 family.

Phylogenomic databases

Ensembl GeneTree

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GeneTreei
ENSGT00390000016655

Identification of Orthologs from Complete Genome Data

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OMAi
VVKEIRC

Database of Orthologous Groups

More...
OrthoDBi
1187027at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P0DMU9

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR029307 INT_SG_DDX_CT_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P0DMU9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS
60 70 80 90 100
AMSKEKKLMT GHAIPPSQLD SQIDDFTGFS KDGMMQKPGS NAPVGGNVTS
110 120 130 140 150
NFSGDDLECR GIASSPKSQQ EINADIKCQV VKEIRCLGRK YEKIFEMLEG
160 170 180
VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI
Length:189
Mass (Da):21,145
Last modified:May 27, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0C4B366EE7BB9E49
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK292207 mRNA Translation: BAF84896.1
AC240441 Genomic DNA No translation available.
BC070138 mRNA Translation: AAH70138.1
BC144429 mRNA Translation: AAI44430.1
BC144430 mRNA Translation: AAI44431.1
BC144527 mRNA Translation: AAI44528.1
BC144528 mRNA Translation: AAI44529.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS76035.1

NCBI Reference Sequences

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RefSeqi
NP_001278456.1, NM_001291527.1
NP_001278457.1, NM_001291528.1
NP_001278458.1, NM_001291529.1
NP_001278459.1, NM_001291530.1
XP_011529540.1, XM_011531238.2
XP_011529541.1, XM_011531239.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000611668; ENSP00000484601; ENSG00000269586
ENST00000617981; ENSP00000481558; ENSG00000269586

Database of genes from NCBI RefSeq genomes

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GeneIDi
102723631

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:102723631

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK292207 mRNA Translation: BAF84896.1
AC240441 Genomic DNA No translation available.
BC070138 mRNA Translation: AAH70138.1
BC144429 mRNA Translation: AAI44430.1
BC144430 mRNA Translation: AAI44431.1
BC144527 mRNA Translation: AAI44528.1
BC144528 mRNA Translation: AAI44529.1
CCDSiCCDS76035.1
RefSeqiNP_001278456.1, NM_001291527.1
NP_001278457.1, NM_001291528.1
NP_001278458.1, NM_001291529.1
NP_001278459.1, NM_001291530.1
XP_011529540.1, XM_011531238.2
XP_011529541.1, XM_011531239.1

3D structure databases

SMRiP0DMU9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP0DMU9, 4 interactors
STRINGi9606.ENSP00000484601

PTM databases

iPTMnetiP0DMU9
PhosphoSitePlusiP0DMU9

Polymorphism and mutation databases

BioMutaiCT45A10

Proteomic databases

jPOSTiP0DMU9
PaxDbiP0DMU9
PeptideAtlasiP0DMU9
PRIDEiP0DMU9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000611668; ENSP00000484601; ENSG00000269586
ENST00000617981; ENSP00000481558; ENSG00000269586
GeneIDi102723631
KEGGihsa:102723631

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
102723631

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CT45A10
HGNCiHGNC:51263 CT45A10
HPAiHPA044735
HPA044757
HPA046872
HPA046987
neXtProtiNX_P0DMU9
OpenTargetsiENSG00000269586

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00390000016655
OMAiVVKEIRC
OrthoDBi1187027at2759
PhylomeDBiP0DMU9

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
102723631

Protein Ontology

More...
PROi
PR:P0DMU9

Gene expression databases

BgeeiENSG00000269586 Expressed in 33 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR029307 INT_SG_DDX_CT_C
PfamiView protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCT45A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0DMU9
Secondary accession number(s): A8K842, B7ZMC5, Q6NSH3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2015
Last sequence update: May 27, 2015
Last modified: May 8, 2019
This is version 24 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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