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Protein

Cancer/testis antigen family 45 member A5

Gene

CT45A5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • snRNA 3'-end processing Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Cancer/testis antigen family 45 member A5Imported
Alternative name(s):
Cancer/testis antigen 45-51 Publication
Cancer/testis antigen 45A5Curated
Gene namesi
Name:CT45A5Imported
Synonyms:CT45-51 Publication
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000228836.8
HGNCiHGNC:33270 CT45A5
MIMi300796 gene
neXtProtiNX_P0DMU8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000228836
ENSG00000278289

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003089501 – 189Cancer/testis antigen family 45 member A5Add BLAST189

Proteomic databases

PRIDEiP0DMU8

PTM databases

iPTMnetiP0DMU8
PhosphoSitePlusiP0DMU8

Expressioni

Tissue specificityi

Testis specific. Expressed in cancer cell lines.1 Publication

Gene expression databases

BgeeiENSG00000228836 Expressed in 31 organ(s), highest expression level in lung

Organism-specific databases

HPAiHPA044735
HPA044757
HPA046872
HPA046987

Structurei

3D structure databases

ProteinModelPortaliP0DMU8
SMRiP0DMU8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CT45 family.

Phylogenomic databases

OMAiRIFKFEG
OrthoDBiEOG091G0L2U

Family and domain databases

InterProiView protein in InterPro
IPR029307 INT_SG_DDX_CT_C
PfamiView protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit

Sequencei

Sequence statusi: Complete.

P0DMU8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS
60 70 80 90 100
AMSKEKKLMT GHAIPPSQLD SQIDDFTGFS KDGMMQKPGS NAPVGGNVTS
110 120 130 140 150
SFSGDDLECR ETASSPKSQR EINADIKRKL VKELRCVGQK YEKIFEMLEG
160 170 180
VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI
Length:189
Mass (Da):21,232
Last modified:May 27, 2015 - v1
Checksum:i202C0D8DB6D6F042
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti101S → N in AAW66468 (PubMed:15905330).Curated1
Sequence conflicti101S → N in CAI41550 (PubMed:15772651).Curated1
Sequence conflicti111 – 112ET → GI in AAW66468 (PubMed:15905330).Curated2
Sequence conflicti111 – 112ET → GI in CAI41550 (PubMed:15772651).Curated2
Sequence conflicti120R → Q in AAW66468 (PubMed:15905330).Curated1
Sequence conflicti120R → Q in CAI41550 (PubMed:15772651).Curated1
Sequence conflicti128 – 139RKLVK…RCVGQ → CQVVKEIRCLGR in AAW66468 (PubMed:15905330).CuratedAdd BLAST12
Sequence conflicti128 – 139RKLVK…RCVGQ → CQVVKEIRCLGR in CAI41550 (PubMed:15772651).CuratedAdd BLAST12

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY743713 mRNA Translation: AAW66468.1
AC240441 Genomic DNA No translation available.
AL590618 Genomic DNA Translation: CAI41550.1
CCDSiCCDS35406.1
RefSeqiNP_001007552.2, NM_001007551.4
NP_001017438.2, NM_001017438.2
NP_001165759.2, NM_001172288.2
NP_001278456.1, NM_001291527.1
NP_001278457.1, NM_001291528.1
NP_001278458.1, NM_001291529.1
NP_001278459.1, NM_001291530.1
NP_001278472.1, NM_001291543.1
XP_003960131.1, XM_003960082.4
XP_005262482.2, XM_005262425.4
XP_011529531.1, XM_011531229.2
XP_011529540.1, XM_011531238.2
XP_011529541.1, XM_011531239.1
XP_011529643.1, XM_011531341.2
XP_011529653.1, XM_011531351.1
UniGeneiHs.535080
Hs.535081
Hs.676560

Genome annotation databases

EnsembliENST00000487941; ENSP00000427342; ENSG00000228836
ENST00000617203; ENSP00000483658; ENSG00000228836
GeneIDi101060211
102723631
441521
541465
KEGGihsa:101060211
hsa:102723631
hsa:441521
hsa:541465

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY743713 mRNA Translation: AAW66468.1
AC240441 Genomic DNA No translation available.
AL590618 Genomic DNA Translation: CAI41550.1
CCDSiCCDS35406.1
RefSeqiNP_001007552.2, NM_001007551.4
NP_001017438.2, NM_001017438.2
NP_001165759.2, NM_001172288.2
NP_001278456.1, NM_001291527.1
NP_001278457.1, NM_001291528.1
NP_001278458.1, NM_001291529.1
NP_001278459.1, NM_001291530.1
NP_001278472.1, NM_001291543.1
XP_003960131.1, XM_003960082.4
XP_005262482.2, XM_005262425.4
XP_011529531.1, XM_011531229.2
XP_011529540.1, XM_011531238.2
XP_011529541.1, XM_011531239.1
XP_011529643.1, XM_011531341.2
XP_011529653.1, XM_011531351.1
UniGeneiHs.535080
Hs.535081
Hs.676560

3D structure databases

ProteinModelPortaliP0DMU8
SMRiP0DMU8
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiP0DMU8
PhosphoSitePlusiP0DMU8

Proteomic databases

PRIDEiP0DMU8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000487941; ENSP00000427342; ENSG00000228836
ENST00000617203; ENSP00000483658; ENSG00000228836
GeneIDi101060211
102723631
441521
541465
KEGGihsa:101060211
hsa:102723631
hsa:441521
hsa:541465

Organism-specific databases

CTDi101060211
102723631
441521
541465
EuPathDBiHostDB:ENSG00000228836.8
GeneCardsiCT45A5
HGNCiHGNC:33270 CT45A5
HPAiHPA044735
HPA044757
HPA046872
HPA046987
MIMi300796 gene
neXtProtiNX_P0DMU8
OpenTargetsiENSG00000228836
ENSG00000278289
GenAtlasiSearch...

Phylogenomic databases

OMAiRIFKFEG
OrthoDBiEOG091G0L2U

Miscellaneous databases

PROiPR:P0DMU8
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000228836 Expressed in 31 organ(s), highest expression level in lung

Family and domain databases

InterProiView protein in InterPro
IPR029307 INT_SG_DDX_CT_C
PfamiView protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCT455_HUMAN
AccessioniPrimary (citable) accession number: P0DMU8
Secondary accession number(s): A8K842, B7ZMC5, Q6NSH3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 7, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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