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Protein

Cancer/testis antigen family 45 member A6

Gene

CT45A6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • snRNA 3'-end processing Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Cancer/testis antigen family 45 member A6Imported
Alternative name(s):
Cancer/testis antigen 45-61 Publication
Cancer/testis antigen 45A6Curated
Gene namesi
Name:CT45A6Imported
Synonyms:CT45-61 Publication
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000278289.4
HGNCiHGNC:33271 CT45A6
MIMi300797 gene
neXtProtiNX_P0DMU7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000228836
ENSG00000278289

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004331171 – 189Cancer/testis antigen family 45 member A6Add BLAST189

Proteomic databases

PeptideAtlasiP0DMU7
PRIDEiP0DMU7

PTM databases

iPTMnetiP0DMU7
PhosphoSitePlusiP0DMU7

Expressioni

Tissue specificityi

Testis specific. Expressed in cancer cell lines.1 Publication

Gene expression databases

BgeeiENSG00000278289 Expressed in 23 organ(s), highest expression level in adenohypophysis

Organism-specific databases

HPAiHPA044735
HPA044757
HPA046872
HPA046987

Structurei

3D structure databases

ProteinModelPortaliP0DMU7
SMRiP0DMU7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CT45 family.

Phylogenomic databases

OrthoDBiEOG091G0L2U

Family and domain databases

InterProiView protein in InterPro
IPR029307 INT_SG_DDX_CT_C
PfamiView protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit

Sequencei

Sequence statusi: Complete.

P0DMU7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS
60 70 80 90 100
AMSKEKKLMT GHAIPPSQLD SQIDDFTGFS KDGMMQKPGS NAPVGGNVTS
110 120 130 140 150
SFSGDDLECR ETASSPKSQR EINADIKRKL VKELRCVGQK YEKIFEMLEG
160 170 180
VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI
Length:189
Mass (Da):21,232
Last modified:May 27, 2015 - v1
Checksum:i202C0D8DB6D6F042
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti55E → A in CAI41551 (PubMed:15772651).Curated1
Sequence conflicti55E → A in AAW66469 (PubMed:15905330).Curated1
Sequence conflicti83G → R in CAI41551 (PubMed:15772651).Curated1
Sequence conflicti83G → R in AAW66469 (PubMed:15905330).Curated1
Sequence conflicti120R → Q in CAI41551 (PubMed:15772651).Curated1
Sequence conflicti120R → Q in AAW66469 (PubMed:15905330).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY743714 mRNA Translation: AAW66469.1
AC240441 Genomic DNA No translation available.
AL590618 Genomic DNA Translation: CAI41551.1
CCDSiCCDS35407.1
RefSeqiNP_001007552.2, NM_001007551.4
NP_001017438.2, NM_001017438.2
NP_001165759.2, NM_001172288.2
NP_001278472.1, NM_001291543.1
XP_003960131.1, XM_003960082.4
XP_005262482.2, XM_005262425.4
XP_011529531.1, XM_011531229.2
XP_011529643.1, XM_011531341.2
XP_011529653.1, XM_011531351.1
UniGeneiHs.535080
Hs.676560

Genome annotation databases

EnsembliENST00000612878; ENSP00000483910; ENSG00000278289
ENST00000620654; ENSP00000479608; ENSG00000278289
GeneIDi101060211
441521
541465
KEGGihsa:101060211
hsa:441521
hsa:541465

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY743714 mRNA Translation: AAW66469.1
AC240441 Genomic DNA No translation available.
AL590618 Genomic DNA Translation: CAI41551.1
CCDSiCCDS35407.1
RefSeqiNP_001007552.2, NM_001007551.4
NP_001017438.2, NM_001017438.2
NP_001165759.2, NM_001172288.2
NP_001278472.1, NM_001291543.1
XP_003960131.1, XM_003960082.4
XP_005262482.2, XM_005262425.4
XP_011529531.1, XM_011531229.2
XP_011529643.1, XM_011531341.2
XP_011529653.1, XM_011531351.1
UniGeneiHs.535080
Hs.676560

3D structure databases

ProteinModelPortaliP0DMU7
SMRiP0DMU7
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiP0DMU7
PhosphoSitePlusiP0DMU7

Proteomic databases

PeptideAtlasiP0DMU7
PRIDEiP0DMU7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000612878; ENSP00000483910; ENSG00000278289
ENST00000620654; ENSP00000479608; ENSG00000278289
GeneIDi101060211
441521
541465
KEGGihsa:101060211
hsa:441521
hsa:541465

Organism-specific databases

CTDi101060211
441521
541465
EuPathDBiHostDB:ENSG00000278289.4
GeneCardsiCT45A6
HGNCiHGNC:33271 CT45A6
HPAiHPA044735
HPA044757
HPA046872
HPA046987
MIMi300797 gene
neXtProtiNX_P0DMU7
OpenTargetsiENSG00000228836
ENSG00000278289
GenAtlasiSearch...

Phylogenomic databases

OrthoDBiEOG091G0L2U

Miscellaneous databases

PROiPR:P0DMU7
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000278289 Expressed in 23 organ(s), highest expression level in adenohypophysis

Family and domain databases

InterProiView protein in InterPro
IPR029307 INT_SG_DDX_CT_C
PfamiView protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCT456_HUMAN
AccessioniPrimary (citable) accession number: P0DMU7
Secondary accession number(s): Q8N7B7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 7, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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