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Entry version 49 (16 Jan 2019)
Sequence version 1 (06 Feb 2013)
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Protein

Zinc finger protein 728

Gene

ZNF728

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri228 – 250C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri256 – 278C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 306C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri312 – 334C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri340 – 362C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri368 – 390C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri396 – 418C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri452 – 474C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri480 – 502C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri508 – 530C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri536 – 558C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri564 – 586C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri592 – 614C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 728
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF728
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000269067.1

Human Gene Nomenclature Database

More...
HGNCi
HGNC:32463 ZNF728

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P0DKX0

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000269067

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF728

Domain mapping of disease mutations (DMDM)

More...
DMDMi
449061972

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004210231 – 622Zinc finger protein 728Add BLAST622

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P0DKX0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P0DKX0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P0DKX0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P0DKX0

PeptideAtlas

More...
PeptideAtlasi
P0DKX0

PRoteomics IDEntifications database

More...
PRIDEi
P0DKX0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P0DKX0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P0DKX0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000269067 Expressed in 72 organ(s), highest expression level in heart

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P0DKX0 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000471593

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P0DKX0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P0DKX0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 75KRABPROSITE-ProRule annotationAdd BLAST72

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri228 – 250C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri256 – 278C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 306C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri312 – 334C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri340 – 362C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri368 – 390C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri396 – 418C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri452 – 474C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri480 – 502C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri508 – 530C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri536 – 558C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri564 – 586C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri592 – 614C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153236

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P0DKX0

Identification of Orthologs from Complete Genome Data

More...
OMAi
KWSSNLM

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 14 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 9 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P0DKX0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSLTFRDVA IQFSLEEWQC LDTAQQNLYR NVMLENYRNL VFLGIAAPKP
60 70 80 90 100
DLIIFLEQGK EPWNMKRHEL VKEPPVICSH FAQDLWPEQG REDSFQKVIL
110 120 130 140 150
RRYEKCGHEN LQLKIGCTNV DECKVHKKGY NKLNQSLTTT QSKVFQCGKY
160 170 180 190 200
ANIFHKCSNS KRHKIRHTGK KLLKCKEYVR SFCMLSHLSQ HKRIYTRENS
210 220 230 240 250
YKSEEHGKAF NWSSALTYKR IHTGEKPCKC EECGKAFSKF SILTKHKVIH
260 270 280 290 300
TGEKHYKCEE CGKAFTRSSS LIEHKRSHAG EKPYKCEECG KAFSKASTLT
310 320 330 340 350
AHKTIHAGEK PYKCEECGKA FNRSSNLMEH KRIHTGEKPC KCEECGKAFG
360 370 380 390 400
NFSTLTKHKV IHTGEKPYKC EECGKAFSWP SSLTEHKRIH AGDKPYKCEE
410 420 430 440 450
CGKTFKWSST LTKHKIIHTG EKPYKCEECG KAFTTFSSLT KHKVIHTGEK
460 470 480 490 500
HYKCEECGKV FSWSSSLTTH KAIHAGEKLY KCEECGKAFK WSSNLMEHKR
510 520 530 540 550
IHTGEKPYKC EECGKAFSKV ANLTKHKVIH TGEKQYKCEE CGKAFIWSSR
560 570 580 590 600
LSEHKRIHTG EKPYKCEECG KAFSWVSVLN KHKKIHAGKK FYKCEECGKD
610 620
FNQSSHLTTH KRIHTGGKTL QM
Length:622
Mass (Da):71,801
Last modified:February 6, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3C6857B813210100
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QZ07M0QZ07_HUMAN
Zinc finger protein 728
ZNF728
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC011502 Genomic DNA No translation available.
AC074135 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS59370.1

NCBI Reference Sequences

More...
RefSeqi
NP_001254645.1, NM_001267716.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.616766

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000594710; ENSP00000471593; ENSG00000269067

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
388523

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:388523

UCSC genome browser

More...
UCSCi
uc002nqz.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011502 Genomic DNA No translation available.
AC074135 Genomic DNA No translation available.
CCDSiCCDS59370.1
RefSeqiNP_001254645.1, NM_001267716.1
UniGeneiHs.616766

3D structure databases

ProteinModelPortaliP0DKX0
SMRiP0DKX0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000471593

PTM databases

iPTMnetiP0DKX0
PhosphoSitePlusiP0DKX0

Polymorphism and mutation databases

BioMutaiZNF728
DMDMi449061972

Proteomic databases

EPDiP0DKX0
jPOSTiP0DKX0
MaxQBiP0DKX0
PaxDbiP0DKX0
PeptideAtlasiP0DKX0
PRIDEiP0DKX0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000594710; ENSP00000471593; ENSG00000269067
GeneIDi388523
KEGGihsa:388523
UCSCiuc002nqz.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
388523
EuPathDBiHostDB:ENSG00000269067.1

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF728
HGNCiHGNC:32463 ZNF728
neXtProtiNX_P0DKX0
OpenTargetsiENSG00000269067

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000153236
InParanoidiP0DKX0
OMAiKWSSNLM
OrthoDBi1318335at2759

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
388523

Protein Ontology

More...
PROi
PR:P0DKX0

Gene expression databases

BgeeiENSG00000269067 Expressed in 72 organ(s), highest expression level in heart
ExpressionAtlasiP0DKX0 baseline and differential

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 11 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 14 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 9 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 14 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN728_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0DKX0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2013
Last sequence update: February 6, 2013
Last modified: January 16, 2019
This is version 49 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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