UniProtKB - P0DKQ1 (CM3F_CONCN)
Protein
Conotoxin CnIIIF
Gene
N/A
Organism
Conus consors (Singed cone)
Status
Functioni
Shows a paralytic effect in fish.1 Publication
Miscellaneous
Found in injectable (milked) (IV) venom.1 Publication
GO - Molecular functioni
- toxin activity Source: UniProtKB-KW
Keywordsi
Molecular function | Neurotoxin, Toxin |
Names & Taxonomyi
Protein namesi | Recommended name: Conotoxin CnIIIF |
Organismi | Conus consors (Singed cone) |
Taxonomic identifieri | 101297 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Lophotrochozoa › Mollusca › Gastropoda › Caenogastropoda › Neogastropoda › Conoidea › Conidae › Conus › Pionoconus |
Subcellular locationi
Extracellular region or secreted
- Secreted 1 Publication
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
PeptideiPRO_0000419880 | 1 – 22 | Conotoxin CnIIIFAdd BLAST | 22 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 2 ↔ 21 | By similarity | ||
Disulfide bondi | 3 ↔ 19 | By similarity | ||
Disulfide bondi | 9 ↔ 22 | By similarity |
Keywords - PTMi
Disulfide bondExpressioni
Tissue specificityi
Expressed by the venom duct.1 Publication
Family & Domainsi
Domaini
The cysteine framework is III (CC-C-C-CC). Classified in the M-1 branch, since 1 residue stands between the fourth and the fifth cysteine residues.Curated
Sequence similaritiesi
Belongs to the conotoxin M superfamily.Curated
i Sequence
Sequence statusi: Complete.
Mass spectrometryi
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
MobiDBi | Search... |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Family and domain databases
ProtoNeti | Search... |
Entry informationi
Entry namei | CM3F_CONCN | |
Accessioni | P0DKQ1Primary (citable) accession number: P0DKQ1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2012 |
Last sequence update: | October 31, 2012 | |
Last modified: | September 12, 2018 | |
This is version 8 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Animal Toxin Annotation Program |