Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 22 (11 Dec 2019)
Sequence version 1 (24 Jul 2013)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Truncated polyprotein 1aTF

Gene
N/A
Organism
Porcine reproductive and respiratory syndrome virus (isolate Pig/United States/SD 01-08/2001) (PRRSV)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

is essential for viral subgenomic mRNA synthesis.By similarity
inhibits IFN-beta production. Counteracts the action of NF-kappaB by decreasing the phosphorylation of IkappaB-alpha, such that the degradation of IkappaB-alpha is suppressed. This leads to the blockage of NF-kappaB nuclear translocation and thus interference of NF-kappaB activation. Also seems to inhibit IRF3-dependent pathways (By similarity).By similarity
Nsp1-beta transactivates the programmed ribosomal frameshifting event leading to the expression of the 1aTF polyprotein.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei76For Nsp1-alpha papain-like cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei146For Nsp1-alpha papain-like cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei276For Nsp1-beta papain-like cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei345For Nsp1-beta papain-like cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei429For Nsp2 cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei498For Nsp2 cysteine proteinase activityPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri8 – 28C4-type; atypicalAdd BLAST21

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicase, Hydrolase, Protease, Thiol protease
Biological processHost-virus interaction
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Truncated polyprotein 1aTF
Cleaved into the following 4 chains:
Nsp1 (EC:3.4.22.-)
Nsp1-alpha papain-like cysteine proteinase (EC:3.4.22.-)
Alternative name(s):
PCP1-alpha
Nsp1-beta papain-like cysteine proteinase (EC:3.4.22.-)
Alternative name(s):
PCP1-beta
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPorcine reproductive and respiratory syndrome virus (isolate Pig/United States/SD 01-08/2001) (PRRSV)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri857306 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesRiboviriaNidoviralesArnidovirineaeArteriviridaeunclassified Arteriviridae
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiSus scrofa (Pig) [TaxID: 9823]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000937 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1119 – 1139HelicalSequence analysisAdd BLAST21
Transmembranei1153 – 1173HelicalSequence analysisAdd BLAST21
Transmembranei1194 – 1214HelicalSequence analysisAdd BLAST21
Transmembranei1233 – 1253HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm, Host endoplasmic reticulum, Host membrane, Host nucleus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Knockout mutants display reduced infectivity.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004231611 – 1268Truncated polyprotein 1aTFSequence analysisAdd BLAST1268
ChainiPRO_00004231621 – 384Nsp1By similarityAdd BLAST384
ChainiPRO_00004231631 – 180Nsp1-alpha papain-like cysteine proteinaseSequence analysisAdd BLAST180
ChainiPRO_0000423164181 – 385Nsp1-beta papain-like cysteine proteinaseSequence analysisAdd BLAST205
ChainiPRO_0000423165386 – 1268Nsp2TFBy similarityAdd BLAST883

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei180 – 181Cleavage; by autolysisSequence analysis2
Sitei385 – 386Cleavage; by autolysisBy similarity2

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P0DJY0

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P0DJY0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini69 – 180Peptidase C31PROSITE-ProRule annotationAdd BLAST112
Domaini269 – 385Peptidase C32PROSITE-ProRule annotationAdd BLAST117
Domaini420 – 527Peptidase C33PROSITE-ProRule annotationAdd BLAST108

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni69 – 182PCP1-alphaBy similarityAdd BLAST114
Regioni269 – 384PCP1-betaBy similarityAdd BLAST116

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri8 – 28C4-type; atypicalAdd BLAST21

Keywords - Domaini

Transmembrane, Transmembrane helix, Zinc-finger

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.70.60, 1 hit
3.90.70.70, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008743 Arterivirus_Nsp2_C33
IPR008741 AV_PCPalpha
IPR038155 AV_PCPalpha_sf
IPR025773 AV_PCPbeta
IPR038154 AV_PCPbeta_sf
IPR032855 NSP2-B_epitope
IPR032841 NSP2_assoc

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14757 NSP2-B_epitope, 1 hit
PF14758 NSP2_assoc, 1 hit
PF05410 Peptidase_C31, 1 hit
PF05411 Peptidase_C32, 1 hit
PF05412 Peptidase_C33, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51538 AV_CP, 1 hit
PS51539 AV_PCP_ALPHA, 1 hit
PS51540 AV_PCP_BETA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by ribosomal frameshifting. AlignAdd to basket
Isoform Truncated polyprotein 1aTF (identifier: P0DJY0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSGTFSRCMC TPAARVFWNA GQVFCTRCLS ARPLLSPELQ DTDLGVVGLF
60 70 80 90 100
YKPKDKIHWK VPIGIPQVEC TPSGCCWLSA VFPLARMTSG NHNFLQRLVK
110 120 130 140 150
VADVLYRDGC LAPRHLRELQ VYERGCSWYP ITGPVPGMGL FANSMHVSDQ
160 170 180 190 200
PFPGATHVLT NSPLPQRACR QPFCPFEEAH SDVYRWKKFV IFTDSSPNGR
210 220 230 240 250
FRMMWTPESD DSAALEVLPP ELERQVEILT RSFPAHHPIN LADWELTESP
260 270 280 290 300
ENGFSFGTSH SCGHIVQNPN VFDGKCWLTC FLGQSAEVCY HEEHLANALG
310 320 330 340 350
YQTKWGVHGK YLQRRLQVRG MRAVVDPDGP IHVEALSCSQ SWVRHLTLNN
360 370 380 390 400
DVTPGFVRLT SIRIVSNTEP TAFRIFRFGA HKWYGAAGKR ARAKRATKSG
410 420 430 440 450
KDSALAPKIA PPVPTCGITT YSPPTDGSCG WHVLAAIVNR MINGDFTSPL
460 470 480 490 500
PQYNRPEDDW ASDYDLAQAI QCLQLPATVV RNRACPNAKY LIKLNGVHWE
510 520 530 540 550
VEVRSGMAPR SLSRECVVGV CSEGCVAPPY PADGLPKRAL EALASAYRLP
560 570 580 590 600
SDCVSSGIAD FLADPPPQEF WTLDKMLTSP SPERSGFSSL YKLLLEVVPQ
610 620 630 640 650
KCGATEGAFV YAVERMLKDC PSPEQAMALL AKIKVPSSKA PSVSLDECFP
660 670 680 690 700
AGVPADFEPA FQERPRSPGA AVALCSPDAK GFEGTASEEA QESGHKAVHA
710 720 730 740 750
VPLAEGPNNE QVQVVAGEQL ELGGCGLAIG SAQSSSDSKR ENMHNSREDE
760 770 780 790 800
PLDLSHPAPA ATTTLVGEQT PDNPGSDASA LPIAVRGFVP TGPILRHVEH
810 820 830 840 850
CGTESGDSSS PLDLSFAQTL DQPLDLSLAA WPVKATASDP GWVRGRCEPV
860 870 880 890 900
FLKPRKAFSD GDSALQFGEL SESSSVIEFD QTKDTLVADA PVDLTTSNEA
910 920 930 940 950
LSAVDPSEFV ELRRPRHSAQ ALIDRGGPLA DVHAKIKNRV YEQCLQACEP
960 970 980 990 1000
GSRATPATRE WLDKMWDRVD MKTWRCTSQF QAGRILASLK FLPDMIQDTP
1010 1020 1030 1040 1050
PPVPRKNRAS DNAGLKQLVA RWDKKLSVTP PPKSAGLVLD QTVPPPTDIQ
1060 1070 1080 1090 1100
QEDATPSDGL SHASDFSSRV STSWSWKGLM LSGTRLAGSA GQRLMTWVFL
1110 1120 1130 1140 1150
KFTPISQLLY SHFSRRGALW LQAIGCLQVL FYLLSCSVVL TQYSDAFPYW
1160 1170 1180 1190 1200
VSFLVLCGVF VWVFLVLGWL LLYFYSRLHP TQSVLLVTTI RRNVMLSFWL
1210 1220 1230 1240 1250
LSSANFGNLC AALWLAPQVS YVSSLASYSV GHVISGMLSY VYACLQIWPF
1260
LLFMWCPKGV VTSVGESV
Note: Produced by -2 ribosomal frameshifting in the nsp2 gene.
Length:1,268
Mass (Da):139,092
Last modified:July 24, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1F4FC8488B70AA65
GO
Isoform Replicase polyprotein 1ab (identifier: A0MD28-1) [UniParc]FASTAAdd to basket
Also known as: pp1ab
The sequence of this isoform can be found in the external entry A0MD28.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:3,838
Mass (Da):418,948
GO
Isoform Replicase polyprotein 1a (identifier: A0MD28-2) [UniParc]FASTAAdd to basket
Also known as: pp1a, ORF1a polyprotein
The sequence of this isoform can be found in the external entry A0MD28.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:2,379
Mass (Da):257,784
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY375474 Genomic RNA No translation available.
DQ489311 Genomic RNA No translation available.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY375474 Genomic RNA No translation available.
DQ489311 Genomic RNA No translation available.

3D structure databases

SMRiP0DJY0
ModBaseiSearch...

Proteomic databases

PRIDEiP0DJY0

Family and domain databases

Gene3Di3.90.70.60, 1 hit
3.90.70.70, 1 hit
InterProiView protein in InterPro
IPR008743 Arterivirus_Nsp2_C33
IPR008741 AV_PCPalpha
IPR038155 AV_PCPalpha_sf
IPR025773 AV_PCPbeta
IPR038154 AV_PCPbeta_sf
IPR032855 NSP2-B_epitope
IPR032841 NSP2_assoc
PfamiView protein in Pfam
PF14757 NSP2-B_epitope, 1 hit
PF14758 NSP2_assoc, 1 hit
PF05410 Peptidase_C31, 1 hit
PF05411 Peptidase_C32, 1 hit
PF05412 Peptidase_C33, 1 hit
PROSITEiView protein in PROSITE
PS51538 AV_CP, 1 hit
PS51539 AV_PCP_ALPHA, 1 hit
PS51540 AV_PCP_BETA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry namei1ATF_PRRSS
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0DJY0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2013
Last sequence update: July 24, 2013
Last modified: December 11, 2019
This is version 22 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again