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UniProtKB - P0DJR0 (GIMD1_HUMAN)
Protein
GTPase IMAP family member GIMD1
Gene
GIMD1
Organism
Homo sapiens (Human)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 36 | GTPBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 15 – 23 | GTPBy similarity | 9 | |
Nucleotide bindingi | 148 – 150 | GTPBy similarity | 3 |
GO - Molecular functioni
- GTP binding Source: UniProtKB-KW
Keywordsi
Ligand | GTP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: GTPase IMAP family member GIMD1Alternative name(s): GIMAP family P-loop NTPase domain-containing protein 1 |
Gene namesi | Name:GIMD1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:44141, GIMD1 |
neXtProti | NX_P0DJR0 |
VEuPathDBi | HostDB:ENSG00000250298 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 100507096 |
OpenTargetsi | ENSG00000250298 |
Miscellaneous databases
Pharosi | P0DJR0, Tdark |
Genetic variation databases
BioMutai | GIMD1 |
DMDMi | 408407619 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000419199 | 1 – 217 | GTPase IMAP family member GIMD1Add BLAST | 217 |
Proteomic databases
MassIVEi | P0DJR0 |
PeptideAtlasi | P0DJR0 |
PRIDEi | P0DJR0 |
PTM databases
iPTMneti | P0DJR0 |
PhosphoSitePlusi | P0DJR0 |
Expressioni
Gene expression databases
ExpressionAtlasi | P0DJR0, baseline and differential |
Organism-specific databases
HPAi | ENSG00000250298, Tissue enriched (intestine) |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 217 | AIG1-type GPROSITE-ProRule annotationAdd BLAST | 212 |
Sequence similaritiesi
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.Curated
Phylogenomic databases
GeneTreei | ENSGT00530000069080 |
InParanoidi | P0DJR0 |
OMAi | WKDFTAV |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR006703, G_AIG1 IPR045058, GIMA/IAN/Toc IPR027417, P-loop_NTPase |
PANTHERi | PTHR10903, PTHR10903, 1 hit |
Pfami | View protein in Pfam PF04548, AIG1, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS51720, G_AIG1, 1 hit |
i Sequence
Sequence statusi: Complete.
P0DJR0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTDPNKMIIN LALFGMTQSG KSSAGNILLG STDFHSSFAP CSVTTCCSLG
60 70 80 90 100
RSCHLHSFMR RGGLEVALQV QVLDTPGYPH SRLSKKYVKQ EVKEALAHHF
110 120 130 140 150
GQGGLHLALL VQRADVPFCG QEVTDPVQMI QELLGHAWMN YTAILFTHAE
160 170 180 190 200
KIEEAGLTED KYLHEASDTL KTLLNSIQHK YVFQYKKGKS LNEQRMKILE
210
RIMEFIKENC YQVLTFK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC093680 Genomic DNA No translation available. DN831977 mRNA No translation available. |
CCDSi | CCDS82942.1 |
RefSeqi | NP_001182067.1, NM_001195138.1 |
Genome annotation databases
Ensembli | ENST00000507153.2; ENSP00000489975.1; ENSG00000250298.6 ENST00000638719.4; ENSP00000491450.2; ENSG00000250298.6 |
GeneIDi | 100507096 |
KEGGi | hsa:100507096 |
MANE-Selecti | ENST00000638719.4; ENSP00000491450.2; NM_001195138.2; NP_001182067.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC093680 Genomic DNA No translation available. DN831977 mRNA No translation available. |
CCDSi | CCDS82942.1 |
RefSeqi | NP_001182067.1, NM_001195138.1 |
3D structure databases
AlphaFoldDBi | P0DJR0 |
SMRi | P0DJR0 |
ModBasei | Search... |
PTM databases
iPTMneti | P0DJR0 |
PhosphoSitePlusi | P0DJR0 |
Genetic variation databases
BioMutai | GIMD1 |
DMDMi | 408407619 |
Proteomic databases
MassIVEi | P0DJR0 |
PeptideAtlasi | P0DJR0 |
PRIDEi | P0DJR0 |
Protocols and materials databases
DNASUi | 100507096 |
Genome annotation databases
Ensembli | ENST00000507153.2; ENSP00000489975.1; ENSG00000250298.6 ENST00000638719.4; ENSP00000491450.2; ENSG00000250298.6 |
GeneIDi | 100507096 |
KEGGi | hsa:100507096 |
MANE-Selecti | ENST00000638719.4; ENSP00000491450.2; NM_001195138.2; NP_001182067.1 |
Organism-specific databases
CTDi | 100507096 |
DisGeNETi | 100507096 |
GeneCardsi | GIMD1 |
HGNCi | HGNC:44141, GIMD1 |
HPAi | ENSG00000250298, Tissue enriched (intestine) |
neXtProti | NX_P0DJR0 |
OpenTargetsi | ENSG00000250298 |
VEuPathDBi | HostDB:ENSG00000250298 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00530000069080 |
InParanoidi | P0DJR0 |
OMAi | WKDFTAV |
Miscellaneous databases
BioGRID-ORCSi | 100507096, 12 hits in 188 CRISPR screens |
Pharosi | P0DJR0, Tdark |
PROi | PR:P0DJR0 |
RNActi | P0DJR0, protein |
Gene expression databases
ExpressionAtlasi | P0DJR0, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR006703, G_AIG1 IPR045058, GIMA/IAN/Toc IPR027417, P-loop_NTPase |
PANTHERi | PTHR10903, PTHR10903, 1 hit |
Pfami | View protein in Pfam PF04548, AIG1, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS51720, G_AIG1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GIMD1_HUMAN | |
Accessioni | P0DJR0Primary (citable) accession number: P0DJR0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 3, 2012 |
Last sequence update: | October 3, 2012 | |
Last modified: | May 25, 2022 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 4
Human chromosome 4: entries, gene names and cross-references to MIM - SIMILARITY comments
Index of protein domains and families