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Protein

Protein PET100 homolog, mitochondrial

Gene

PET100

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • unfolded protein binding Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PET100 homolog, mitochondrial
Gene namesi
Name:PET100
Synonyms:C19orf79
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000229833.9
HGNCiHGNC:40038 PET100
MIMi614770 gene
neXtProtiNX_P0DJ07

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 24HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane, Mitochondrion

Pathology & Biotechi

Organism-specific databases

DisGeNETi100131801
MalaCardsiPET100
OpenTargetsiENSG00000229833
Orphaneti255241 Leigh syndrome with leukodystrophy

Polymorphism and mutation databases

DMDMi353558869

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000413099? – 73Protein PET100 homolog, mitochondrial
Transit peptidei1 – ?Mitochondrion

Proteomic databases

EPDiP0DJ07
MaxQBiP0DJ07
PaxDbiP0DJ07
PeptideAtlasiP0DJ07
PRIDEiP0DJ07
ProteomicsDBi52536
TopDownProteomicsiP0DJ07

PTM databases

iPTMnetiP0DJ07
PhosphoSitePlusiP0DJ07

Expressioni

Gene expression databases

BgeeiENSG00000229833 Expressed in 95 organ(s), highest expression level in heart
ExpressionAtlasiP0DJ07 baseline and differential
GenevisibleiP0DJ07 HS

Organism-specific databases

HPAiHPA067288

Interactioni

Subunit structurei

Interacts with COX7A2.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9606.ENSP00000470539

Structurei

3D structure databases

ProteinModelPortaliP0DJ07
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PET100 family.Curated

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4702 Eukaryota
ENOG411230W LUCA
GeneTreeiENSGT00390000016884
InParanoidiP0DJ07
KOiK18186
OMAiLEVFRMT
OrthoDBiEOG091G16E5
PhylomeDBiP0DJ07
TreeFamiTF314727

Family and domain databases

InterProiView protein in InterPro
IPR018625 Pet100
PANTHERiPTHR33968 PTHR33968, 1 hit
PfamiView protein in Pfam
PF09803 Pet100, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P0DJ07-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVKLEIFRM IIYLTFPVAM FWVSNQAEWF EDDVIQRKRE LWPPEKLQEI
60 70
EEFKERLRKR REEKLLRDAQ QNS
Length:73
Mass (Da):9,114
Last modified:October 19, 2011 - v1
Checksum:iCE20E13A4155616C
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QZ55M0QZ55_HUMAN
Protein PET100 homolog, mitochondri...
PET100
46Annotation score:
M0R022M0R022_HUMAN
Protein PET100 homolog, mitochondri...
PET100
68Annotation score:
A0A0A0MSK2A0A0A0MSK2_HUMAN
Protein PET100 homolog, mitochondri...
PET100
44Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008763 Genomic DNA No translation available.
BC150496 mRNA No translation available.
CCDSiCCDS54208.1
RefSeqiNP_001164626.1, NM_001171155.1
UniGeneiHs.728837

Genome annotation databases

EnsembliENST00000594797; ENSP00000470539; ENSG00000229833
GeneIDi100131801
KEGGihsa:100131801
UCSCiuc010dvi.3 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008763 Genomic DNA No translation available.
BC150496 mRNA No translation available.
CCDSiCCDS54208.1
RefSeqiNP_001164626.1, NM_001171155.1
UniGeneiHs.728837

3D structure databases

ProteinModelPortaliP0DJ07
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000470539

PTM databases

iPTMnetiP0DJ07
PhosphoSitePlusiP0DJ07

Polymorphism and mutation databases

DMDMi353558869

Proteomic databases

EPDiP0DJ07
MaxQBiP0DJ07
PaxDbiP0DJ07
PeptideAtlasiP0DJ07
PRIDEiP0DJ07
ProteomicsDBi52536
TopDownProteomicsiP0DJ07

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000594797; ENSP00000470539; ENSG00000229833
GeneIDi100131801
KEGGihsa:100131801
UCSCiuc010dvi.3 human

Organism-specific databases

CTDi100131801
DisGeNETi100131801
EuPathDBiHostDB:ENSG00000229833.9
GeneCardsiPET100
HGNCiHGNC:40038 PET100
HPAiHPA067288
MalaCardsiPET100
MIMi614770 gene
neXtProtiNX_P0DJ07
OpenTargetsiENSG00000229833
Orphaneti255241 Leigh syndrome with leukodystrophy
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4702 Eukaryota
ENOG411230W LUCA
GeneTreeiENSGT00390000016884
InParanoidiP0DJ07
KOiK18186
OMAiLEVFRMT
OrthoDBiEOG091G16E5
PhylomeDBiP0DJ07
TreeFamiTF314727

Miscellaneous databases

ChiTaRSiPET100 human
PROiPR:P0DJ07
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000229833 Expressed in 95 organ(s), highest expression level in heart
ExpressionAtlasiP0DJ07 baseline and differential
GenevisibleiP0DJ07 HS

Family and domain databases

InterProiView protein in InterPro
IPR018625 Pet100
PANTHERiPTHR33968 PTHR33968, 1 hit
PfamiView protein in Pfam
PF09803 Pet100, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPT100_HUMAN
AccessioniPrimary (citable) accession number: P0DJ07
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 7, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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