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Protein

60S ribosomal protein L41-B

Gene

RPL41B

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.1 Publication

Miscellaneous

Present with 4910 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for eL41 in yeast.Curated

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29533-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L41-B1 Publication
Alternative name(s):
L47
Large ribosomal subunit protein eL41-B1 Publication
YL41
Gene namesi
Name:RPL41B1 Publication
Synonyms:RPL47B, YL41B
Ordered Locus Names:YDL133C-A
ORF Names:YDL133BC
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

SGDiS000002293 RPL41B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004104481 – 2560S ribosomal protein L41-BAdd BLAST25

Expressioni

Gene expression databases

ExpressionAtlasiP0CX87 differential

Interactioni

Subunit structurei

Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:9559554, PubMed:22096102).1 Publication1 Publication

Protein-protein interaction databases

BioGridi31860, 85 interactors
31928, 51 interactors

Structurei

3D structure databases

ProteinModelPortaliP0CX87
SMRiP0CX87
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2 – 23Arg-richAdd BLAST22

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00860000136181
KOiK02928

Family and domain databases

InterProiView protein in InterPro
IPR007836 Ribosomal_L41
PfamiView protein in Pfam
PF05162 Ribosomal_L41, 1 hit

Sequencei

Sequence statusi: Complete.

P0CX87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
MRAKWRKKRT RRLKRKRRKV RARSK
Length:25
Mass (Da):3,337
Last modified:June 28, 2011 - v1
Checksum:iBD2629DD9ED85381
GO

Mass spectrometryi

Molecular mass is 3335.103 Da from positions 1 - 25. Determined by ESI. Monoisotopic mass.1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16066 Genomic DNA Translation: CAA34202.1
X96876 Genomic DNA Translation: CAA65626.1
Z74181 Genomic DNA Translation: CAA98705.1
Z74182 Genomic DNA Translation: CAA98706.1
BK006938 Genomic DNA Translation: DAA11725.1
PIRiS22246 R6BY4B
RefSeqiNP_010097.1, NM_001180244.1
NP_010148.1, NM_001180194.1

Genome annotation databases

EnsemblFungiiYDL133C-A; YDL133C-A; YDL133C-A
YDL184C; YDL184C; YDL184C
GeneIDi851344
851422
KEGGisce:YDL133C-A
sce:YDL184C

Similar proteinsi

Entry informationi

Entry nameiRL41B_YEAST
AccessioniPrimary (citable) accession number: P0CX87
Secondary accession number(s): D6VRG8, P05746
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: June 28, 2011
Last modified: July 18, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

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