Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Coiled-coil domain-containing protein 166

Gene

CCDC166

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 166
Gene namesi
Name:CCDC166
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000255181.3
HGNCiHGNC:41910 CCDC166
neXtProtiNX_P0CW27

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000255181

Polymorphism and mutation databases

BioMutaiCCDC166
DMDMi347602472

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004122241 – 439Coiled-coil domain-containing protein 166Add BLAST439

Proteomic databases

PaxDbiP0CW27
PeptideAtlasiP0CW27
PRIDEiP0CW27
ProteomicsDBi52525

PTM databases

iPTMnetiP0CW27
PhosphoSitePlusiP0CW27

Expressioni

Gene expression databases

BgeeiENSG00000255181 Expressed in 5 organ(s), highest expression level in testis

Organism-specific databases

HPAiHPA025058

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000437468

Structurei

3D structure databases

ProteinModelPortaliP0CW27
SMRiP0CW27
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili27 – 74Sequence analysisAdd BLAST48
Coiled coili121 – 213Sequence analysisAdd BLAST93

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi288 – 410Ser-richAdd BLAST123

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IWCJ Eukaryota
ENOG4111HGH LUCA
GeneTreeiENSGT00510000049871
InParanoidiP0CW27
OMAiHREHEDT
OrthoDBiEOG091G0TEA
PhylomeDBiP0CW27
TreeFamiTF343581

Family and domain databases

InterProiView protein in InterPro
IPR029584 CCDC166
IPR032777 DUF4515
PANTHERiPTHR14845:SF4 PTHR14845:SF4, 1 hit
PfamiView protein in Pfam
PF14988 DUF4515, 1 hit

Sequencei

Sequence statusi: Complete.

P0CW27-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPKKKRGPS AGSQPGGAAA AGAEQPLSER AQYLQREHAL LSEQLDTCEE
60 70 80 90 100
SVDQVLRENA FLDREALRLR EENRLYASYV SARAQRCAKA IVRLDEQNRV
110 120 130 140 150
DLAQIHWQRA ELASLYHGRE DGVRAQLLEM EARAAQMAQQ VQELQPYKVL
160 170 180 190 200
QLEQLARIRA LERELLHMRV EHTQLLHRVK RRFLEDKAAF EREARQRVQS
210 220 230 240 250
LARRAEREAV RALVAHTQAI KADNGRLRQE LLLLLRRTQL LHHTRRQLLE
260 270 280 290 300
QREQLHREHE DTRDLARVHG WLRRGPGGPP LWERPAFSQP TSRPGSLAAP
310 320 330 340 350
ISPSRAASQT PSVVPSRAAP RASSVVPSRE ASRVPSLVLS SMDSRVPSLA
360 370 380 390 400
TSKVGSRMPS LTASRAGSRA LSLVQSLEGS GISSGSSPRV SSQDTLRSTK
410 420 430
SGPKLLSGLS RDRDPALLPP QSEDSVNAEA AAEASPGRA
Length:439
Mass (Da):48,709
Last modified:September 21, 2011 - v1
Checksum:i6394873C2985C8A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105219 Genomic DNA No translation available.
CCDSiCCDS55280.1
RefSeqiNP_001156386.1, NM_001162914.1
UniGeneiHs.730002

Genome annotation databases

EnsembliENST00000533508; ENSP00000437315; ENSG00000278749
ENST00000542437; ENSP00000437468; ENSG00000255181
GeneIDi100130274
KEGGihsa:100130274
UCSCiuc011lkr.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105219 Genomic DNA No translation available.
CCDSiCCDS55280.1
RefSeqiNP_001156386.1, NM_001162914.1
UniGeneiHs.730002

3D structure databases

ProteinModelPortaliP0CW27
SMRiP0CW27
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000437468

PTM databases

iPTMnetiP0CW27
PhosphoSitePlusiP0CW27

Polymorphism and mutation databases

BioMutaiCCDC166
DMDMi347602472

Proteomic databases

PaxDbiP0CW27
PeptideAtlasiP0CW27
PRIDEiP0CW27
ProteomicsDBi52525

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000533508; ENSP00000437315; ENSG00000278749
ENST00000542437; ENSP00000437468; ENSG00000255181
GeneIDi100130274
KEGGihsa:100130274
UCSCiuc011lkr.2 human

Organism-specific databases

CTDi100130274
EuPathDBiHostDB:ENSG00000255181.3
GeneCardsiCCDC166
HGNCiHGNC:41910 CCDC166
HPAiHPA025058
neXtProtiNX_P0CW27
OpenTargetsiENSG00000255181
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IWCJ Eukaryota
ENOG4111HGH LUCA
GeneTreeiENSGT00510000049871
InParanoidiP0CW27
OMAiHREHEDT
OrthoDBiEOG091G0TEA
PhylomeDBiP0CW27
TreeFamiTF343581

Miscellaneous databases

PROiPR:P0CW27

Gene expression databases

BgeeiENSG00000255181 Expressed in 5 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR029584 CCDC166
IPR032777 DUF4515
PANTHERiPTHR14845:SF4 PTHR14845:SF4, 1 hit
PfamiView protein in Pfam
PF14988 DUF4515, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCC166_HUMAN
AccessioniPrimary (citable) accession number: P0CW27
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 7, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again