UniProtKB - P0CW24 (PNM6A_HUMAN)
Protein
Paraneoplastic antigen-like protein 6A
Gene
PNMA6A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Paraneoplastic antigen-like protein 6ACurated |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:28248, PNMA6A |
MIMi | 300917, gene |
neXtProti | NX_P0CW24 |
VEuPathDBi | HostDB:ENSG00000235961.5 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000235961 |
Miscellaneous databases
Pharosi | P0CW24, Tdark |
Genetic variation databases
BioMutai | PNMA6A |
DMDMi | 342165258 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000311219 | 1 – 399 | Paraneoplastic antigen-like protein 6AAdd BLAST | 399 |
Proteomic databases
jPOSTi | P0CW24 |
MassIVEi | P0CW24 |
PaxDbi | P0CW24 |
PeptideAtlasi | P0CW24 |
PRIDEi | P0CW24 |
ProteomicsDBi | 52523 52524 |
PTM databases
iPTMneti | P0CW24 |
PhosphoSitePlusi | P0CW24 |
Expressioni
Tissue specificityi
Expressed in the brain.1 Publication
Gene expression databases
Bgeei | ENSG00000235961, Expressed in substantia nigra and 159 other tissues |
Organism-specific databases
HPAi | ENSG00000235961, Tissue enhanced (brain) |
Interactioni
Binary interactionsi
Hide detailsP0CW24
With | #Exp. | IntAct |
---|---|---|
ARMC7 [Q9H6L4] | 3 | EBI-721270,EBI-742909 |
CCDC103 [Q8IW40] | 3 | EBI-721270,EBI-10261970 |
CRX [O43186] | 3 | EBI-721270,EBI-748171 |
PNMA1 [Q8ND90] | 7 | EBI-721270,EBI-302345 |
Protein-protein interaction databases
BioGRIDi | 124398, 6 interactors |
IntActi | P0CW24, 5 interactors |
STRINGi | 9606.ENSP00000391488 |
Miscellaneous databases
RNActi | P0CW24, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the PNMA family.Curated
Phylogenomic databases
eggNOGi | KOG3544, Eukaryota |
GeneTreei | ENSGT01010000222436 |
InParanoidi | P0CW24 |
OMAi | VCWLRSI |
OrthoDBi | 820525at2759 |
PhylomeDBi | P0CW24 |
TreeFami | TF335054 |
Family and domain databases
InterProi | View protein in InterPro IPR026523, PNMA |
PANTHERi | PTHR23095, PTHR23095, 1 hit |
Pfami | View protein in Pfam PF14893, PNMA, 1 hit |
i Sequence
Sequence statusi: Complete.
P0CW24-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAVTMLQDWC RWMGVNARRG LLILGIPEDC DDAEFQESLE AALRPMGHFT
60 70 80 90 100
VLGKAFREED NATAALVELD REVNYALVPR EIPGTGGPWN VVFVPRCSGE
110 120 130 140 150
EFLGLGRVFH FPEQEGQMVE SVAGALGVGL RRVCWLRSIG QAVQPWVEAV
160 170 180 190 200
RCQSLGVFSG RDQPAPGEES FEVWLDHTTE MLHVWQGVSE RERRRRLLEG
210 220 230 240 250
LRGTALQLVH ALLAENPART AQDCLAALAQ VFGDNESQAT IRVKCLTAQQ
260 270 280 290 300
QSGERLSAFV LRLEVLLQKA MEKEALARAS ADRVRLRQML TRAHLTEPLD
310 320 330 340 350
EALRKLRMAG RSPSFLEMLG LVRESEAWEA SLARSVRAQT QEGAGARAGA
360 370 380 390
QAVARASTKV EAVPGGPGRE PEGLLQAGGQ EAEELLQEGL KPVLEECDN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK055322 mRNA Translation: BAB70902.1 AK289879 mRNA Translation: BAF82568.1 AC243374 Genomic DNA No translation available. AC243428 Genomic DNA No translation available. CH471172 Genomic DNA Translation: EAW72886.1 CH471172 Genomic DNA Translation: EAW72887.1 BC007631 mRNA Translation: AAH07631.1 |
CCDSi | CCDS14719.1 |
RefSeqi | NP_116271.3, NM_032882.5 |
Genome annotation databases
Ensembli | ENST00000421798; ENSP00000391488; ENSG00000235961 |
GeneIDi | 84968 |
KEGGi | hsa:84968 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK055322 mRNA Translation: BAB70902.1 AK289879 mRNA Translation: BAF82568.1 AC243374 Genomic DNA No translation available. AC243428 Genomic DNA No translation available. CH471172 Genomic DNA Translation: EAW72886.1 CH471172 Genomic DNA Translation: EAW72887.1 BC007631 mRNA Translation: AAH07631.1 |
CCDSi | CCDS14719.1 |
RefSeqi | NP_116271.3, NM_032882.5 |
3D structure databases
SMRi | P0CW24 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 124398, 6 interactors |
IntActi | P0CW24, 5 interactors |
STRINGi | 9606.ENSP00000391488 |
PTM databases
iPTMneti | P0CW24 |
PhosphoSitePlusi | P0CW24 |
Genetic variation databases
BioMutai | PNMA6A |
DMDMi | 342165258 |
Proteomic databases
jPOSTi | P0CW24 |
MassIVEi | P0CW24 |
PaxDbi | P0CW24 |
PeptideAtlasi | P0CW24 |
PRIDEi | P0CW24 |
ProteomicsDBi | 52523 52524 |
Protocols and materials databases
Antibodypediai | 72662, 71 antibodies |
DNASUi | 84968 |
Genome annotation databases
Ensembli | ENST00000421798; ENSP00000391488; ENSG00000235961 |
GeneIDi | 84968 |
KEGGi | hsa:84968 |
Organism-specific databases
CTDi | 84968 |
GeneCardsi | PNMA6A |
HGNCi | HGNC:28248, PNMA6A |
HPAi | ENSG00000235961, Tissue enhanced (brain) |
MIMi | 300917, gene |
neXtProti | NX_P0CW24 |
OpenTargetsi | ENSG00000235961 |
VEuPathDBi | HostDB:ENSG00000235961.5 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3544, Eukaryota |
GeneTreei | ENSGT01010000222436 |
InParanoidi | P0CW24 |
OMAi | VCWLRSI |
OrthoDBi | 820525at2759 |
PhylomeDBi | P0CW24 |
TreeFami | TF335054 |
Enzyme and pathway databases
PathwayCommonsi | P0CW24 |
Miscellaneous databases
BioGRID-ORCSi | 84968, 47 hits in 520 CRISPR screens |
GenomeRNAii | 84968 |
Pharosi | P0CW24, Tdark |
PROi | PR:P0CW24 |
RNActi | P0CW24, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000235961, Expressed in substantia nigra and 159 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR026523, PNMA |
PANTHERi | PTHR23095, PTHR23095, 1 hit |
Pfami | View protein in Pfam PF14893, PNMA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PNM6A_HUMAN | |
Accessioni | P0CW24Primary (citable) accession number: P0CW24 Secondary accession number(s): A8K1G4 Q96A40 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 27, 2011 |
Last sequence update: | October 14, 2015 | |
Last modified: | April 7, 2021 | |
This is version 74 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome X
Human chromosome X: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families