Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Paraneoplastic antigen-like protein 6A

Gene

PNMA6A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Paraneoplastic antigen-like protein 6ACurated
Gene namesi
Name:PNMA6AImported
Synonyms:PNMA6CImported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000235961.5
HGNCiHGNC:28248 PNMA6A
MIMi300917 gene
neXtProtiNX_P0CW24

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000235961

Polymorphism and mutation databases

BioMutaiPNMA6C
DMDMi342165258

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003112191 – 399Paraneoplastic antigen-like protein 6AAdd BLAST399

Proteomic databases

PaxDbiP0CW24
PeptideAtlasiP0CW24
PRIDEiP0CW24
ProteomicsDBi52523
52524

PTM databases

iPTMnetiP0CW24
PhosphoSitePlusiP0CW24

Expressioni

Tissue specificityi

Expressed in the brain.1 Publication

Gene expression databases

BgeeiENSG00000235961 Expressed in 133 organ(s), highest expression level in substantia nigra
CleanExiHS_PNMA6A

Organism-specific databases

HPAiHPA045007
HPA052115

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PNMA1Q8ND906EBI-721270,EBI-302345

Protein-protein interaction databases

BioGridi124398, 2 interactors
IntActiP0CW24, 4 interactors

Structurei

3D structure databases

ProteinModelPortaliP0CW24
SMRiP0CW24
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PNMA family.Curated

Phylogenomic databases

eggNOGiENOG410J9MD Eukaryota
ENOG41117XE LUCA
GeneTreeiENSGT00530000062986
HOGENOMiHOG000013079
HOVERGENiHBG052488
InParanoidiP0CW24
OMAiRWMGVSA
OrthoDBiEOG091G0BG9
PhylomeDBiP0CW24
TreeFamiTF335054

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
PANTHERiPTHR23095 PTHR23095, 2 hits
PfamiView protein in Pfam
PF14893 PNMA, 1 hit

Sequencei

Sequence statusi: Complete.

P0CW24-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVTMLQDWC RWMGVNARRG LLILGIPEDC DDAEFQESLE AALRPMGHFT
60 70 80 90 100
VLGKAFREED NATAALVELD REVNYALVPR EIPGTGGPWN VVFVPRCSGE
110 120 130 140 150
EFLGLGRVFH FPEQEGQMVE SVAGALGVGL RRVCWLRSIG QAVQPWVEAV
160 170 180 190 200
RCQSLGVFSG RDQPAPGEES FEVWLDHTTE MLHVWQGVSE RERRRRLLEG
210 220 230 240 250
LRGTALQLVH ALLAENPART AQDCLAALAQ VFGDNESQAT IRVKCLTAQQ
260 270 280 290 300
QSGERLSAFV LRLEVLLQKA MEKEALARAS ADRVRLRQML TRAHLTEPLD
310 320 330 340 350
EALRKLRMAG RSPSFLEMLG LVRESEAWEA SLARSVRAQT QEGAGARAGA
360 370 380 390
QAVARASTKV EAVPGGPGRE PEGLLQAGGQ EAEELLQEGL KPVLEECDN
Length:399
Mass (Da):43,875
Last modified:October 14, 2015 - v2
Checksum:i256F5733C3EBB07D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055322 mRNA Translation: BAB70902.1
AK289879 mRNA Translation: BAF82568.1
AC243374 Genomic DNA No translation available.
AC243428 Genomic DNA No translation available.
CH471172 Genomic DNA Translation: EAW72886.1
CH471172 Genomic DNA Translation: EAW72887.1
BC007631 mRNA Translation: AAH07631.1
CCDSiCCDS14719.1
RefSeqiNP_116271.3, NM_032882.5
UniGeneiHs.533301
Hs.721963

Genome annotation databases

EnsembliENST00000421798; ENSP00000391488; ENSG00000235961
GeneIDi84968
KEGGihsa:84968

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055322 mRNA Translation: BAB70902.1
AK289879 mRNA Translation: BAF82568.1
AC243374 Genomic DNA No translation available.
AC243428 Genomic DNA No translation available.
CH471172 Genomic DNA Translation: EAW72886.1
CH471172 Genomic DNA Translation: EAW72887.1
BC007631 mRNA Translation: AAH07631.1
CCDSiCCDS14719.1
RefSeqiNP_116271.3, NM_032882.5
UniGeneiHs.533301
Hs.721963

3D structure databases

ProteinModelPortaliP0CW24
SMRiP0CW24
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124398, 2 interactors
IntActiP0CW24, 4 interactors

PTM databases

iPTMnetiP0CW24
PhosphoSitePlusiP0CW24

Polymorphism and mutation databases

BioMutaiPNMA6C
DMDMi342165258

Proteomic databases

PaxDbiP0CW24
PeptideAtlasiP0CW24
PRIDEiP0CW24
ProteomicsDBi52523
52524

Protocols and materials databases

DNASUi84968
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000421798; ENSP00000391488; ENSG00000235961
GeneIDi84968
KEGGihsa:84968

Organism-specific databases

CTDi84968
EuPathDBiHostDB:ENSG00000235961.5
GeneCardsiPNMA6A
HGNCiHGNC:28248 PNMA6A
HPAiHPA045007
HPA052115
MIMi300917 gene
neXtProtiNX_P0CW24
OpenTargetsiENSG00000235961
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J9MD Eukaryota
ENOG41117XE LUCA
GeneTreeiENSGT00530000062986
HOGENOMiHOG000013079
HOVERGENiHBG052488
InParanoidiP0CW24
OMAiRWMGVSA
OrthoDBiEOG091G0BG9
PhylomeDBiP0CW24
TreeFamiTF335054

Miscellaneous databases

GenomeRNAii84968
PROiPR:P0CW24
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000235961 Expressed in 133 organ(s), highest expression level in substantia nigra
CleanExiHS_PNMA6A

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
PANTHERiPTHR23095 PTHR23095, 2 hits
PfamiView protein in Pfam
PF14893 PNMA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPNM6A_HUMAN
AccessioniPrimary (citable) accession number: P0CW24
Secondary accession number(s): A8K1G4
, D3DWT8, P0CW26, Q96A40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: October 14, 2015
Last modified: November 7, 2018
This is version 58 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again