PNMA6A

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Paraneoplastic antigen-like protein 6ACurated
Gene namesⁱ	Name:PNMA6AImported Synonyms:PNMA6CImported
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome X

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000235961.5
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:28248 PNMA6A
MIMⁱ	300917 gene
neXtProtⁱ	NX_P0CW24

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000235961

OpenTargetsⁱ

ENSG00000235961

Polymorphism and mutation databases

BioMutaⁱ	PNMA6C
DMDMⁱ	342165258

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000311219	1 – 399	Paraneoplastic antigen-like protein 6AAdd BLAST		399

Proteomic databases

PaxDbⁱ	P0CW24
PeptideAtlas More...PeptideAtlasⁱ	P0CW24
PRIDEⁱ	P0CW24
ProteomicsDBⁱ	52523 52524

PTM databases

iPTMnetⁱ	P0CW24
PhosphoSitePlusⁱ	P0CW24

Expressionⁱ

Tissue specificityⁱ

Expressed in the brain.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000235961 Expressed in 133 organ(s), highest expression level in substantia nigra
CleanExⁱ	HS_PNMA6A

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA045007 HPA052115

HPAⁱ

HPA045007
HPA052115

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
PNMA1	Q8ND90	6	EBI-721270,EBI-302345

With

Entry

#Exp.

IntAct

Notes

PNMA1

Q8ND90

6

EBI-721270,EBI-302345

Protein-protein interaction databases

BioGridⁱ	124398, 2 interactors
IntActⁱ	P0CW24, 4 interactors

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P0CW24
SMRⁱ	P0CW24
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the PNMA family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG410J9MD Eukaryota ENOG41117XE LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000062986
HOGENOMⁱ	HOG000013079
HOVERGENⁱ	HBG052488
InParanoidⁱ	P0CW24
OMAⁱ	RWMGVSA
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BG9
PhylomeDBⁱ	P0CW24
TreeFamⁱ	TF335054

Family and domain databases

InterProⁱ	View protein in InterPro IPR026523 PNMA
PANTHERⁱ	PTHR23095 PTHR23095, 2 hits
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF14893 PNMA, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P0CW24-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAVTMLQDWC RWMGVNARRG LLILGIPEDC DDAEFQESLE AALRPMGHFT 
        60         70         80         90        100
VLGKAFREED NATAALVELD REVNYALVPR EIPGTGGPWN VVFVPRCSGE 
       110        120        130        140        150
EFLGLGRVFH FPEQEGQMVE SVAGALGVGL RRVCWLRSIG QAVQPWVEAV 
       160        170        180        190        200
RCQSLGVFSG RDQPAPGEES FEVWLDHTTE MLHVWQGVSE RERRRRLLEG 
       210        220        230        240        250
LRGTALQLVH ALLAENPART AQDCLAALAQ VFGDNESQAT IRVKCLTAQQ 
       260        270        280        290        300
QSGERLSAFV LRLEVLLQKA MEKEALARAS ADRVRLRQML TRAHLTEPLD 
       310        320        330        340        350
EALRKLRMAG RSPSFLEMLG LVRESEAWEA SLARSVRAQT QEGAGARAGA 
       360        370        380        390 
QAVARASTKV EAVPGGPGRE PEGLLQAGGQ EAEELLQEGL KPVLEECDN

Length:399

Mass (Da):43,875

Last modified:October 14, 2015 - v2

Checksum:ⁱ256F5733C3EBB07D

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK055322 mRNA Translation: BAB70902.1 AK289879 mRNA Translation: BAF82568.1 AC243374 Genomic DNA No translation available. AC243428 Genomic DNA No translation available. CH471172 Genomic DNA Translation: EAW72886.1 CH471172 Genomic DNA Translation: EAW72887.1 BC007631 mRNA Translation: AAH07631.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS14719.1
NCBI Reference Sequences More...RefSeqⁱ	NP_116271.3, NM_032882.5
UniGeneⁱ	Hs.533301 Hs.721963

Genome annotation databases

Ensemblⁱ	ENST00000421798; ENSP00000391488; ENSG00000235961
GeneIDⁱ	84968
KEGGⁱ	hsa:84968

Protein	Similar proteins		Species	Score	Length	Source
P0CW24	Uncharacterized protein		GORGO		400	UniRef90_P0CW24
PNMA6A isoform 1		PANTR		399
Uncharacterized protein		PONAB		399
Uncharacterized protein		PANPA		399
PNMA6A isoform 1		PONAB		399
+2

Protein	Similar proteins		Species	Score	Length	Source
P0CW24	Uncharacterized protein		GORGO		400	UniRef50_P0CW24
Uncharacterized protein		PONAB		399
PNMA6A isoform 1		PANTR		399
Uncharacterized protein		PANPA		399
Uncharacterized protein		CERAT		369
+43

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK055322 mRNA Translation: BAB70902.1 AK289879 mRNA Translation: BAF82568.1 AC243374 Genomic DNA No translation available. AC243428 Genomic DNA No translation available. CH471172 Genomic DNA Translation: EAW72886.1 CH471172 Genomic DNA Translation: EAW72887.1 BC007631 mRNA Translation: AAH07631.1
CCDSⁱ	CCDS14719.1
RefSeqⁱ	NP_116271.3, NM_032882.5
UniGeneⁱ	Hs.533301 Hs.721963

3D structure databases

ProteinModelPortalⁱ	P0CW24
SMRⁱ	P0CW24
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	124398, 2 interactors
IntActⁱ	P0CW24, 4 interactors

PTM databases

iPTMnetⁱ	P0CW24
PhosphoSitePlusⁱ	P0CW24

Polymorphism and mutation databases

BioMutaⁱ	PNMA6C
DMDMⁱ	342165258

Proteomic databases

PaxDbⁱ	P0CW24
PeptideAtlasⁱ	P0CW24
PRIDEⁱ	P0CW24
ProteomicsDBⁱ	52523 52524

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	84968
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000421798; ENSP00000391488; ENSG00000235961
GeneIDⁱ	84968
KEGGⁱ	hsa:84968

Organism-specific databases

CTDⁱ	84968
EuPathDBⁱ	HostDB:ENSG00000235961.5
GeneCardsⁱ	PNMA6A
HGNCⁱ	HGNC:28248 PNMA6A
HPAⁱ	HPA045007 HPA052115
MIMⁱ	300917 gene
neXtProtⁱ	NX_P0CW24
OpenTargetsⁱ	ENSG00000235961
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410J9MD Eukaryota ENOG41117XE LUCA
GeneTreeⁱ	ENSGT00530000062986
HOGENOMⁱ	HOG000013079
HOVERGENⁱ	HBG052488
InParanoidⁱ	P0CW24
OMAⁱ	RWMGVSA
OrthoDBⁱ	EOG091G0BG9
PhylomeDBⁱ	P0CW24
TreeFamⁱ	TF335054

Miscellaneous databases

GenomeRNAiⁱ	84968
Protein Ontology More...PROⁱ	PR:P0CW24
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000235961 Expressed in 133 organ(s), highest expression level in substantia nigra
CleanExⁱ	HS_PNMA6A

Family and domain databases

InterProⁱ	View protein in InterPro IPR026523 PNMA
PANTHERⁱ	PTHR23095 PTHR23095, 2 hits
Pfamⁱ	View protein in Pfam PF14893 PNMA, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	PNM6A_HUMAN
Accessionⁱ	P0CW24Primary (citable) accession number: P0CW24 Secondary accession number(s): A8K1G4 , D3DWT8, P0CW26, Q96A40
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 27, 2011
	Last sequence update:	October 14, 2015
	Last modified:	November 7, 2018
	This is version 58 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome X
Human chromosome X: entries, gene names and cross-references to MIM

UniProtKB

UniParc

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UniRef

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Supporting data

UniProtKB - P0CW24 (PNM6A_HUMAN)

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Paraneoplastic antigen-like protein 6A

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ