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UniProtKB - P0CN88 (ALG13_CRYNJ)
Protein
UDP-N-acetylglucosamine transferase subunit ALG13
Gene
ALG13
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
Status
Functioni
Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity).
By similarityCatalytic activityi
- N-acetyl-α-D-glucosaminyl-diphosphodolichol + UDP-N-acetyl-α-D-glucosamine = H+ + N,N'-diacetylchitobiosyl diphosphodolichol + UDPEC:2.4.1.141
GO - Molecular functioni
- N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- dolichol-linked oligosaccharide biosynthetic process Source: InterPro
Keywordsi
Molecular function | Glycosyltransferase, Transferase |
Names & Taxonomyi
Protein namesi | Recommended name: UDP-N-acetylglucosamine transferase subunit ALG13 (EC:2.4.1.141)Alternative name(s): Asparagine-linked glycosylation protein 13 |
Gene namesi | Name:ALG13 Ordered Locus Names:CNB05490 |
Organismi | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
Taxonomic identifieri | 214684 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Tremellomycetes › Tremellales › Cryptococcaceae › Cryptococcus › Cryptococcus neoformans species complex › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | FungiDB:CNB05490 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum By similarity
Endoplasmic reticulum
- endoplasmic reticulum Source: UniProtKB-SubCell
Keywords - Cellular componenti
Endoplasmic reticulumPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000215600 | 1 – 200 | UDP-N-acetylglucosamine transferase subunit ALG13Add BLAST | 200 |
Proteomic databases
PaxDbi | P0CN88 |
Interactioni
Subunit structurei
Heterodimer with ALG14 to form a functional enzyme.
By similarityProtein-protein interaction databases
STRINGi | 5207.AAW41985 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glycosyltransferase 28 family.Curated
Phylogenomic databases
eggNOGi | KOG3349, Eukaryota |
InParanoidi | P0CN88 |
OrthoDBi | 1575485at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR039042, Alg13-like IPR007235, Glyco_trans_28_C |
PANTHERi | PTHR12867, PTHR12867, 1 hit |
Pfami | View protein in Pfam PF04101, Glyco_tran_28_C, 1 hit |
i Sequence
Sequence statusi: Complete.
P0CN88-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAHPFTLLVT VGSTLFPSLT SHVLLPTFLS LLQSLGVQRL VVQYGRAELK
60 70 80 90 100
LQDDVKQTLN IDSQGDGIGV WSDNDGDRVR DEKQNGMVVE VMRFTNDFEG
110 120 130 140 150
LVGKSDAVIS HAGSGSILTV LRRAPPIPLL VVPNRSLMDD HQSELADALY
160 170 180 190 200
KDGYVMVASV EDLEEKVQPF LKIWPSQAKL FPETRKEVFR EVVDDLMGYD
Sequence cautioni
The sequence AAW41985 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017342 Genomic DNA Translation: AAW41985.1 Sequence problems. |
RefSeqi | XP_569292.1, XM_569292.1 |
Genome annotation databases
EnsemblFungii | AAW41985; AAW41985; CNB05490 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017342 Genomic DNA Translation: AAW41985.1 Sequence problems. |
RefSeqi | XP_569292.1, XM_569292.1 |
3D structure databases
AlphaFoldDBi | P0CN88 |
SMRi | P0CN88 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 5207.AAW41985 |
Proteomic databases
PaxDbi | P0CN88 |
Genome annotation databases
EnsemblFungii | AAW41985; AAW41985; CNB05490 |
Organism-specific databases
VEuPathDBi | FungiDB:CNB05490 |
Phylogenomic databases
eggNOGi | KOG3349, Eukaryota |
InParanoidi | P0CN88 |
OrthoDBi | 1575485at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR039042, Alg13-like IPR007235, Glyco_trans_28_C |
PANTHERi | PTHR12867, PTHR12867, 1 hit |
Pfami | View protein in Pfam PF04101, Glyco_tran_28_C, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ALG13_CRYNJ | |
Accessioni | P0CN88Primary (citable) accession number: P0CN88 Secondary accession number(s): Q55YI6, Q5KLF2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 28, 2011 |
Last sequence update: | June 28, 2011 | |
Last modified: | May 25, 2022 | |
This is version 32 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families